Published in J Chem Inf Model on February 22, 2010
Evaluation of simultaneous cranioplasty and ventriculoperitoneal shunt procedures. J Neurosurg (2014) 1.99
The prevalence and significance of incidental thyroid nodules identified on computed tomography. J Comput Assist Tomogr (2008) 1.24
Nuclear factor-kappaB activation correlates with better prognosis and Akt activation in human gastric cancer. Clin Cancer Res (2005) 1.22
Akt/PKB activation in gastric carcinomas correlates with clinicopathologic variables and prognosis. APMIS (2003) 1.21
A hypoxia-independent up-regulation of hypoxia-inducible factor-1 by AKT contributes to angiogenesis in human gastric cancer. Carcinogenesis (2007) 1.01
Antitumor agents 252. Application of validated QSAR models to database mining: discovery of novel tylophorine derivatives as potential anticancer agents. J Comput Aided Mol Des (2007) 1.01
Combinatorial QSAR of ambergris fragrance compounds. J Chem Inf Comput Sci (2004) 0.98
Electrostatic steering at acetylcholine binding sites. Biophys J (2006) 0.94
HTS and rational drug design to generate a class of 5-HT(2C)-selective ligands for possible use in schizophrenia. ChemMedChem (2010) 0.94
Constitutive activation of signal transducers and activators of transcription 3 correlates with better prognosis, cell proliferation and hypoxia-inducible factor-1α in human gastric cancer. Pathobiology (2011) 0.94
Manganese superoxide dismutase expression correlates with a poor prognosis in gastric cancer. Pathobiology (2003) 0.93
Constitutive phosphorylation of the FOXO1A transcription factor as a prognostic variable in gastric cancer. Mod Pathol (2007) 0.92
Prediction of aqueous solubility of organic compounds using a quantitative structure-property relationship. J Pharm Sci (2002) 0.92
Anticancer activity of 3-O-acyl and alkyl-(-)-epicatechin derivatives. Bioorg Med Chem Lett (2004) 0.91
Computed pore potentials of the nicotinic acetylcholine receptor. Biophys J (2006) 0.89
Manganese superoxide dismutase expression correlates with chemosensitivity in human gastric cancer cell lines. Clin Cancer Res (2003) 0.88
Transcriptome analysis in the midgut of the earthworm (Eisenia andrei) using expressed sequence tags. Biochem Biophys Res Commun (2005) 0.88
Rational Drug Design Leading to the Identification of a Potent 5-HT(2C) Agonist Lacking 5-HT(2B) Activity. ACS Med Chem Lett (2011) 0.86
Osteosarcoma of the ethmoid sinus. Skeletal Radiol (2004) 0.85
Immunohistochemical analysis of cell cycle-related molecules in gastric carcinoma: prognostic significance, correlation with clinicopathological parameters, proliferation and apoptosis. Pathobiology (2008) 0.85
Morphological study of sinus flow in the confluence of sinuses. Clin Anat (2008) 0.85
Application of QSAR and shape pharmacophore modeling approaches for targeted chemical library design. Methods Mol Biol (2011) 0.84
Constitutive activation of glycogen synthase kinase-3beta correlates with better prognosis and cyclin-dependent kinase inhibitors in human gastric cancer. BMC Gastroenterol (2010) 0.84
Recent progress in the computational prediction of aqueous solubility and absorption. AAPS J (2006) 0.84
Scoring protein interaction decoys using exposed residues (SPIDER): a novel multibody interaction scoring function based on frequent geometric patterns of interfacial residues. Proteins (2012) 0.84
A synergistic interaction between transcription factors nuclear factor-κB and signal transducers and activators of transcription 3 promotes gastric cancer cell migration and invasion. BMC Gastroenterol (2013) 0.83
Novel approach to structure-based pharmacophore search using computational geometry and shape matching techniques. J Chem Inf Model (2008) 0.82
Anaplastic thyroid carcinoma: computed tomographic differentiation from other thyroid masses. Acta Radiol (2008) 0.82
Angiographic results of indirect and combined bypass surgery for adult moyamoya disease. J Cerebrovasc Endovasc Neurosurg (2012) 0.81
Who are susceptible to pseudomembranous colitis among patients with presumed antibiotic-associated diarrhea? Dis Colon Rectum (2006) 0.81
A facile one-pot preparation of alkyl aminoaryl sulfides for the synthesis of GW7647 as an agonist of peroxisome proliferator-activated receptor alpha. J Org Chem (2006) 0.80
Molecular shape technologies in drug discovery: methods and applications. Curr Top Med Chem (2010) 0.80
The COX-2-1195AA Genotype Is Associated with Diffuse-Type Gastric Cancer in Korea. Gut Liver (2012) 0.80
Synthesis and antimicrobial activities of 3-O-alkyl analogues of (+)-catechin: improvement of stability and proposed action mechanism. Eur J Med Chem (2009) 0.80
A new structure-based QSAR method affords both descriptive and predictive models for phosphodiesterase-4 inhibitors. Curr Chem Genomics (2008) 0.79
Unconventional 2D shape similarity method affords comparable enrichment as a 3D shape method in virtual screening experiments. J Chem Inf Model (2009) 0.79
Synthesis and antifungal activity of a novel series of 13-(4-isopropylbenzyl)berberine derivatives. Bioorg Med Chem Lett (2010) 0.78
Receptor-based pharmacophore and pharmacophore key descriptors for virtual screening and QSAR modeling. Curr Comput Aided Drug Des (2011) 0.78
Discovery, design and synthesis of Y-shaped peroxisome proliferator-activated receptor δ agonists as potent anti-obesity agents in vivo. Eur J Med Chem (2012) 0.78
[Frequency of loss of heterozygosity on chromosome 17 in intrahepatic cholangiocarcinoma]. Korean J Gastroenterol (2006) 0.77
Structure-based shape pharmacophore modeling for the discovery of novel anesthetic compounds. Bioorg Med Chem (2009) 0.77
Development of improved models for phosphodiesterase-4 inhibitors with a multi-conformational structure-based QSAR method. Curr Chem Genomics (2009) 0.77
Signal transducers and activators of transcription 3-induced metastatic potential in gastric cancer cells is enhanced by glycogen synthase kinase-3β. APMIS (2015) 0.77
Hybrid quantum mechanical/molecular mechanical molecular dynamics simulations of HIV-1 integrase/inhibitor complexes. Biophys J (2007) 0.77
Informatics approach to the rational design of siRNA libraries. Methods Mol Biol (2011) 0.76
Prognostic significance of computed tomography defined ascites in advanced gastric cancer. J Korean Surg Soc (2012) 0.76
Sudden migration of a thalamic hemorrhage into the ventricles. J Korean Neurosurg Soc (2010) 0.75
Morphometric study of the upper thoracic sympathetic Ganglia. J Korean Neurosurg Soc (2011) 0.75
Assay development and multivariate scoring for high-content discovery of chemoprotectants of endoplasmic-reticulum-stress-mediated amylin-induced cytotoxicity in pancreatic beta cells. Assay Drug Dev Technol (2014) 0.75
Insights of a Lead Optimization Study and Biological Evaluation of Novel 4-Hydroxytamoxifen Analogs as Estrogen-Related Receptor γ (ERRγ) Inverse Agonists. J Med Chem (2016) 0.75
A PCR-based analysis of Hox genes in an earthworm, Eisenia andrei (Annelida: Oligochaeta). Biochem Genet (2004) 0.75
Antimicrobial activity of 3-O-acyl-(-)-epicatechin and 3-O-acyl-(+)-catechin derivatives. Planta Med (2004) 0.75
Testing non-additivity of biological activity in a combinatorial library. Comb Chem High Throughput Screen (2002) 0.75
Structure-based quantitative structure--activity relationship modeling of estrogen receptor β-ligands. Future Med Chem (2011) 0.75
Impairment of nuclear factor-kappaB activation increased glutamate excitotoxicity in a motoneuron-neuroblastoma hybrid cell line expressing mutant (G93A) Cu/Zn-superoxide dismutase. J Neurosci Res (2010) 0.75
Rational principles of compound selection for combinatorial library design. Comb Chem High Throughput Screen (2002) 0.75