Published in Br J Nutr on January 26, 2010
A novel nanoparticle drug delivery system: the anti-inflammatory activity of curcumin is enhanced when encapsulated in exosomes. Mol Ther (2010) 2.29
The delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiology. Physiol Rev (2012) 1.95
The targets of curcumin. Curr Drug Targets (2011) 1.76
Discovery of curcumin, a component of golden spice, and its miraculous biological activities. Clin Exp Pharmacol Physiol (2012) 1.72
Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells. Clin Epigenetics (2011) 1.31
Plants vs. cancer: a review on natural phytochemicals in preventing and treating cancers and their druggability. Anticancer Agents Med Chem (2012) 1.14
Curcumin nanodisks: formulation and characterization. Nanomedicine (2010) 1.12
Modulation of Wnt/β-catenin signaling pathway by bioactive food components. Carcinogenesis (2011) 1.06
Curcumin derivatives promote Schwann cell differentiation and improve neuropathy in R98C CMT1B mice. Brain (2012) 1.05
Inhibition of high glucose-induced inflammatory response and macrophage infiltration by a novel curcumin derivative prevents renal injury in diabetic rats. Br J Pharmacol (2012) 1.02
Curcumin pretreatment induces Nrf2 and an antioxidant response and prevents hemin-induced toxicity in primary cultures of cerebellar granule neurons of rats. Oxid Med Cell Longev (2013) 1.01
Measurement of spices and seasonings in India: opportunities for cancer epidemiology and prevention. Asian Pac J Cancer Prev (2010) 1.00
Nanobiotechnology applications of reconstituted high density lipoprotein. J Nanobiotechnology (2010) 0.97
Prolonged biologically active colonic tissue levels of curcumin achieved after oral administration--a clinical pilot study including assessment of patient acceptability. Cancer Prev Res (Phila) (2012) 0.96
Plant-derived anti-inflammatory compounds: hopes and disappointments regarding the translation of preclinical knowledge into clinical progress. Mediators Inflamm (2014) 0.96
Metabolism as a key to histone deacetylase inhibition. Crit Rev Biochem Mol Biol (2011) 0.95
The novel curcumin analog FLLL32 decreases STAT3 DNA binding activity and expression, and induces apoptosis in osteosarcoma cell lines. BMC Cancer (2011) 0.93
Effects of curcumin on the proliferation and mineralization of human osteoblast-like cells: implications of nitric oxide. Int J Mol Sci (2012) 0.92
The generation of induced pluripotent stem cells for macular degeneration as a drug screening platform: identification of curcumin as a protective agent for retinal pigment epithelial cells against oxidative stress. Front Aging Neurosci (2014) 0.92
The Attenuation of Pain Behavior and Serum COX-2 Concentration by Curcumin in a Rat Model of Neuropathic Pain. Korean J Pain (2014) 0.92
Curcumin Attenuates Iron Accumulation and Oxidative Stress in the Liver and Spleen of Chronic Iron-Overloaded Rats. PLoS One (2015) 0.92
The plant-based immunomodulator curcumin as a potential candidate for the development of an adjunctive therapy for cerebral malaria. Malar J (2011) 0.91
Diverse effects of a low dose supplement of lipidated curcumin in healthy middle aged people. Nutr J (2012) 0.90
Curcumin augments lung maturation, preventing neonatal lung injury by inhibiting TGF-β signaling. Am J Physiol Lung Cell Mol Physiol (2011) 0.88
Antioxidant therapy for treatment of inflammatory bowel disease: Does it work? Redox Biol (2015) 0.87
Dendrosomal curcumin nanoformulation downregulates pluripotency genes via miR-145 activation in U87MG glioblastoma cells. Int J Nanomedicine (2014) 0.87
Curcumin, the main part of turmeric, prevents learning and memory changes induced by sodium metabisulfite, a preservative agent, in rats. Exp Neurobiol (2013) 0.85
Synergistic anti-cancer mechanisms of curcumin and paclitaxel for growth inhibition of human brain tumor stem cells and LN18 and U138MG cells. Neurochem Int (2012) 0.85
Curcuminoid binding to embryonal carcinoma cells: reductive metabolism, induction of apoptosis, senescence, and inhibition of cell proliferation. PLoS One (2012) 0.84
Curcumin Enhances Docetaxel-Induced Apoptosis of 8505C Anaplastic Thyroid Carcinoma Cells. Endocrinol Metab (Seoul) (2014) 0.83
Global microRNA expression profiling: curcumin (diferuloylmethane) alters oxidative stress-responsive microRNAs in human ARPE-19 cells. Mol Vis (2013) 0.83
ApoE enhances nanodisk-mediated curcumin delivery to glioblastoma multiforme cells. Nanomedicine (Lond) (2013) 0.83
Phototoxic effect of curcumin on methicillin-resistant Staphylococcus aureus and L929 fibroblasts. Lasers Med Sci (2012) 0.83
The critical roles of miR-21 in anti-cancer effects of curcumin. Ann Transl Med (2015) 0.83
Synthesis and characterization of dextran coated magnetite nanoparticles for diagnostics and therapy. Bioimpacts (2015) 0.82
Natural compounds as anticancer agents: Experimental evidence. World J Exp Med (2012) 0.82
Pre-administration of turmeric prevents methotrexate-induced liver toxicity and oxidative stress. BMC Complement Altern Med (2015) 0.82
High glucose induces Smad activation via the transcriptional coregulator p300 and contributes to cardiac fibrosis and hypertrophy. Cardiovasc Diabetol (2014) 0.82
Novel Curcumin Diclofenac Conjugate Enhanced Curcumin Bioavailability and Efficacy in Streptococcal Cell Wall-induced Arthritis. Indian J Pharm Sci (2014) 0.81
Cytotoxic effects of curcumin in human retinal pigment epithelial cells. PLoS One (2013) 0.81
In vitro synergistic effect of curcumin in combination with third generation cephalosporins against bacteria associated with infectious diarrhea. Biomed Res Int (2014) 0.81
Oxidative Transformation of Demethoxy- and Bisdemethoxycurcumin: Products, Mechanism of Formation, and Poisoning of Human Topoisomerase IIα. Chem Res Toxicol (2015) 0.81
Curcumin: An effective adjunct in patients with statin-associated muscle symptoms? J Cachexia Sarcopenia Muscle (2016) 0.81
Molecular mechanisms of curcumin and its semisynthetic analogues in prostate cancer prevention and treatment. Life Sci (2016) 0.81
Bisdemethoxycurcumin inhibits PDGF-induced vascular smooth muscle cell motility and proliferation. Mol Nutr Food Res (2013) 0.81
Inhibition of HIV-1 by curcumin A, a novel curcumin analog. Drug Des Devel Ther (2015) 0.80
Streptococcus mutans photoinactivation by combination of short exposure of a broad-spectrum visible light and low concentrations of photosensitizers. Photomed Laser Surg (2014) 0.80
Drug treatment of cancer cell lines: a way to select for cancer stem cells? Cancers (Basel) (2011) 0.80
Curcumin inhibits interferon-γ signaling in colonic epithelial cells. Am J Physiol Gastrointest Liver Physiol (2011) 0.80
Design and in vitro evaluation of a new nano-microparticulate system for enhanced aqueous-phase solubility of curcumin. Biomed Res Int (2013) 0.80
Curcumin-induced heme oxygenase-1 expression prevents H2O2-induced cell death in wild type and heme oxygenase-2 knockout adipose-derived mesenchymal stem cells. Int J Mol Sci (2014) 0.80
Understanding the molecular mechanisms of cancer prevention by dietary phytochemicals: From experimental models to clinical trials. World J Biol Chem (2016) 0.79
Farmer to pharmacist: curcumin as an anti-invasive and antimetastatic agent for the treatment of cancer. Front Chem (2014) 0.79
Curcuminoids limit neutrophil-mediated reperfusion injury in experimental stroke by targeting the endothelium. Microcirculation (2013) 0.79
Analysis of the gene expression profile of curcumin-treated kidney on endotoxin-induced renal inflammation. Inflammation (2013) 0.78
Effect of curcumin on Bcl-2 and Bax expression in nude mice prostate cancer. Int J Clin Exp Pathol (2015) 0.78
Marchantin M Induces Apoptosis of Prostate Cancer Cells Through Endoplasmic Reticulum Stress. Med Sci Monit (2015) 0.78
Mechanistic targets and phytochemical strategies for breaking the obesity-cancer link. Front Oncol (2013) 0.78
Novel low molecular weight lignins as potential anti-emphysema agents: In vitro triple inhibitory activity against elastase, oxidation and inflammation. Pulm Pharmacol Ther (2012) 0.77
Unfolded protein response, treatment and CMT1B. Rare Dis (2013) 0.77
Curcumin Ameliorates Functional and Structural Abnormalities in Cisplatin-induced Neuropathy. Exp Neurobiol (2015) 0.77
Photodynamic inactivation of a multispecies biofilm using curcumin and LED light. Lasers Med Sci (2016) 0.76
Urine and serum analysis of consumed curcuminoids using an IkappaB-luciferase surrogate marker assay. In Vivo (2010) 0.76
Curcumin potentiates antitumor activity of cisplatin in bladder cancer cell lines via ROS-mediated activation of ERK1/2. Oncotarget (2016) 0.76
Potential Antiosteoporotic Natural Product Lead Compounds That Inhibit 17β-Hydroxysteroid Dehydrogenase Type 2. J Nat Prod (2017) 0.75
Curcumin protects against the intestinal ischemia-reperfusion injury: involvement of the tight junction protein ZO-1 and TNF-α related mechanism. Korean J Physiol Pharmacol (2016) 0.75
Polyphenol compounds and PKC signaling. Biochim Biophys Acta (2016) 0.75
Interaction between the antioxidant activity of curcumin and cholinergic system on memory retention in adult male Wistar rats. Iran J Basic Med Sci (2015) 0.75
Effects of Steroids and Curcumin on Prevention of Laryngeal Stenosis Secondary to Trauma. Iran J Otorhinolaryngol (2016) 0.75
Investigation of the effect of short-term supplementation with curcuminoids on circulating small dense low-density lipoprotein concentrations in obese dyslipidemic subjects: A randomized double-blind placebo-controlled cross-over trial. ARYA Atheroscler (2014) 0.75
Synthesis of Aromatic Retinoids and Curcuminoids and Evaluation of their Antiproliferative, Antiradical, and Anti-inflammatory Activities. ChemistryOpen (2016) 0.75
Interleukin (IL)-1β Is a Strong Inducer of IL-36γ Expression in Human Colonic Myofibroblasts. PLoS One (2015) 0.75
Oral Curcumin (Meriva) Is Effective as an Adjuvant Treatment and Is Able to Reduce IL-22 Serum Levels in Patients with Psoriasis Vulgaris. Biomed Res Int (2015) 0.75
Antioxidant activities of curcumin in allergic rhinitis. Eur Arch Otorhinolaryngol (2016) 0.75
Curcumin is a promising inhibitor of genotype 2 porcine reproductive and respiratory syndrome virus infection. BMC Vet Res (2017) 0.75
Curcumin and Curcuma longa L. extract ameliorate lipid accumulation through the regulation of the endoplasmic reticulum redox and ER stress. Sci Rep (2017) 0.75
Photodynamic therapy controls of Staphylococcus aureus intradermal infection in mice. Lasers Med Sci (2017) 0.75
Diarrhoea in children: an interface between developing and developed countries. Lancet (2004) 2.87
Regulation of gut inflammation and th17 cell response by interleukin-21. Gastroenterology (2008) 2.38
Smad7 controls resistance of colitogenic T cells to regulatory T cell-mediated suppression. Gastroenterology (2008) 1.88
IL-23/IL-17 axis in IBD. Inflamm Bowel Dis (2010) 1.71
Anti-inflammatory and growth-stimulating effects precede nutritional restitution during enteral feeding in Crohn disease. J Pediatr Gastroenterol Nutr (2004) 1.65
IL-21 regulates experimental colitis by modulating the balance between Treg and Th17 cells. Eur J Immunol (2007) 1.49
Involvement of interleukin-21 in the epidermal hyperplasia of psoriasis. Nat Med (2009) 1.45
Markers to measure immunomodulation in human nutrition intervention studies. Br J Nutr (2005) 1.42
A functional role for interleukin-21 in promoting the synthesis of the T-cell chemoattractant, MIP-3alpha, by gut epithelial cells. Gastroenterology (2006) 1.38
Prevalence and management of anemia in children, adolescents, and adults with inflammatory bowel disease. Inflamm Bowel Dis (2011) 1.36
Intestinal inflammation-induced growth retardation acts through IL-6 in rats and depends on the -174 IL-6 G/C polymorphism in children. Proc Natl Acad Sci U S A (2005) 1.25
Clinical features affecting final adult height in patients with pediatric-onset Crohn's disease. Pediatrics (2006) 1.18
Delayed puberty associated with inflammatory bowel disease. Pediatr Res (2003) 1.17
New players in the cytokine orchestra of inflammatory bowel disease. Inflamm Bowel Dis (2007) 1.15
Gastrin-induced cyclooxygenase-2 expression in Barrett's carcinogenesis. Clin Cancer Res (2004) 1.12
Interferon-gamma-expressing cells are a major source of interleukin-21 in inflammatory bowel diseases. Inflamm Bowel Dis (2010) 1.12
A rapid diagnostic test for human regulatory T-cell function to enable regulatory T-cell therapy. Blood (2012) 1.10
Dextran sulfate sodium-induced inflammation is enhanced by intestinal epithelial cell chemokine expression in mice. Pediatr Res (2003) 1.08
Myofibroblast matrix metalloproteinases activate the neutrophil chemoattractant CXCL7 from intestinal epithelial cells. Gastroenterology (2006) 1.08
Protease-activated receptor-2 activation in gastric cancer cells promotes epidermal growth factor receptor trans-activation and proliferation. Am J Pathol (2006) 1.06
Micronutrient supplementation has limited effects on intestinal infectious disease and mortality in a Zambian population of mixed HIV status: a cluster randomized trial. Am J Clin Nutr (2008) 1.04
Interleukin-21 (IL-21)-mediated pathways in T cell-mediated disease. Cytokine Growth Factor Rev (2009) 1.03
Role of IL-15 in immune-mediated and infectious diseases. Cytokine Growth Factor Rev (2010) 1.01
The effect of specific caspase inhibitors on TNF-alpha and butyrate-induced apoptosis of intestinal epithelial cells. Exp Cell Res (2004) 1.01
Interleukin-21 as a new therapeutic target for immune-mediated diseases. Trends Pharmacol Sci (2009) 1.00
Interleukin-25: a two-edged sword in the control of immune-inflammatory responses. Cytokine Growth Factor Rev (2010) 0.98
Gastric and intestinal barrier impairment in tropical enteropathy and HIV: limited impact of micronutrient supplementation during a randomised controlled trial. BMC Gastroenterol (2010) 0.93
Genetically modified enterotoxigenic Escherichia coli vaccines induce mucosal immune responses without inflammation. Gut (2007) 0.93
Intestinal infections and environmental enteropathy: Working Group report of the second World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition. J Pediatr Gastroenterol Nutr (2004) 0.93
Smad7 expression in T cells prevents colitis-associated cancer. Cancer Res (2011) 0.93
Butyrate regulates the expression of pathogen-triggered IL-8 in intestinal epithelia. Pediatr Res (2007) 0.92
A role for gut-associated lymphoid tissue in shaping the human B cell repertoire. J Exp Med (2013) 0.91
Intestinal antimicrobial gene expression: impact of micronutrients in malnourished adults during a randomized trial. J Infect Dis (2010) 0.90
Breast milk lactoferrin regulates gene expression by binding bacterial DNA CpG motifs but not genomic DNA promoters in model intestinal cells. Pediatr Res (2006) 0.89
Effect of inflammation on cyclooxygenase (COX)-2 expression in benign and malignant oesophageal cells. Carcinogenesis (2005) 0.88
Sodium butyrate-mediated Sp3 acetylation represses human insulin-like growth factor binding protein-3 expression in intestinal epithelial cells. J Pediatr Gastroenterol Nutr (2006) 0.87
Compartmentalised expression of meprin in small intestinal mucosa: enhanced expression in lamina propria in coeliac disease. Biol Chem (2007) 0.86
Always one step ahead: How pathogenic bacteria use the type III secretion system to manipulate the intestinal mucosal immune system. J Inflamm (Lond) (2011) 0.86
Staphylococcal enterotoxins G and I, a cause of severe but reversible neonatal enteropathy. Clin Gastroenterol Hepatol (2007) 0.84
IL-25 prevents and cures fulminant hepatitis in mice through a myeloid-derived suppressor cell-dependent mechanism. Hepatology (2013) 0.84
The pathophysiologic rationale for biological therapies in inflammatory bowel disease. Curr Opin Gastroenterol (2005) 0.83
Iron status and Helicobacter pylori infection in symptomatic children: an international multi-centered study. PLoS One (2013) 0.83
The role of interleukin 17 in Crohn's disease-associated intestinal fibrosis. Fibrogenesis Tissue Repair (2013) 0.83
Interleukin-21 in cancer immunotherapy: Friend or foe? Oncoimmunology (2012) 0.83
A mouse model of intestinal fibrosis? Gastroenterology (2003) 0.82
Targeting interleukin-21 in immune-mediated pathologies. Curr Drug Targets (2010) 0.82
Inhibition of colon carcinogenesis by 2-methoxy-5-amino-N-hydroxybenzamide, a novel derivative of mesalamine. Gastroenterology (2009) 0.82
Helicobacter pylori regulates the expression of inhibitors of DNA binding (Id) proteins by gastric epithelial cells. Microbes Infect (2006) 0.77
Involvement of CD40-CD40 ligand in uncomplicated and refractory celiac disease. Am J Gastroenterol (2010) 0.77
The immunomodulatory properties of viable Lactobacillus salivarius ssp. salivarius CECT5713 are not restricted to the large intestine. Eur J Nutr (2011) 0.76
IL-1β stimulation of CCD-18co myofibroblasts enhances repair of epithelial monolayers through Wnt-5a. Am J Physiol Gastrointest Liver Physiol (2012) 0.76
Stromelysin-1 and macrophage metalloelastase expression in the intestinal mucosa of Crohn's disease patients treated with infliximab. Eur J Gastroenterol Hepatol (2009) 0.76
Immunology. Curr Opin Gastroenterol (2005) 0.75