Qing-Xin Hua

Author PubWeight™ 7.74‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Mutant INS-gene induced diabetes of youth: proinsulin cysteine residues impose dominant-negative inhibition on wild-type proinsulin transport. PLoS One 2010 1.27
2 How insulin binds: the B-chain alpha-helix contacts the L1 beta-helix of the insulin receptor. J Mol Biol 2004 1.15
3 In vitro refolding of human proinsulin. Kinetic intermediates, putative disulfide-forming pathway folding initiation site, and potential role of C-peptide in folding process. J Biol Chem 2003 1.00
4 Solution structure of proinsulin: connecting domain flexibility and prohormone processing. J Biol Chem 2010 0.99
5 An Achilles' heel in an amyloidogenic protein and its repair: insulin fibrillation and therapeutic design. J Biol Chem 2010 0.91
6 A cavity-forming mutation in insulin induces segmental unfolding of a surrounding alpha-helix. Protein Sci 2002 0.90
7 Crystal structure of a "nonfoldable" insulin: impaired folding efficiency despite native activity. J Biol Chem 2009 0.83
8 Design and folding of [GluA4(ObetaThrB30)]insulin ("ester insulin"): a minimal proinsulin surrogate that can be chemically converted into human insulin. Angew Chem Int Ed Engl 2010 0.79