Published in BMC Med Genet on January 30, 2010
Innate immune recognition of Mycobacterium tuberculosis. Clin Dev Immunol (2011) 1.90
Toll-like receptor -1, -2, and -6 polymorphisms and pulmonary tuberculosis susceptibility: a systematic review and meta-analysis. PLoS One (2013) 1.19
Cellular and humoral mechanisms involved in the control of tuberculosis. Clin Dev Immunol (2012) 1.16
Mycobacterium tuberculosis lipoproteins directly regulate human memory CD4(+) T cell activation via Toll-like receptors 1 and 2. Infect Immun (2010) 1.07
TLR1, 2, 4, 6 and 9 Variants Associated with Tuberculosis Susceptibility: A Systematic Review and Meta-Analysis. PLoS One (2015) 0.93
Variants in toll-like receptor 9 gene influence susceptibility to tuberculosis in a Mexican population. J Transl Med (2013) 0.88
Antitubercular therapy in patients with cirrhosis: challenges and options. World J Gastroenterol (2014) 0.86
The involvement of NADPH oxidase-mediated ROS in cytokine secretion from macrophages induced by Mycobacterium tuberculosis ESAT-6. Inflammation (2014) 0.81
Genetic polymorphisms in Toll-like receptors among pediatric patients with renal parenchymal infections of different clinical severities. PLoS One (2013) 0.80
Genetic polymorphisms of CCL1 rs2072069 G/A and TLR2 rs3804099 T/C in pulmonary or meningeal tuberculosis patients. Int J Clin Exp Pathol (2015) 0.76
Acute Exposure to Crystalline Silica Reduces Macrophage Activation in Response to Bacterial Lipoproteins. Front Immunol (2016) 0.75
Histone H3K14 hypoacetylation and H3K27 hypermethylation along with HDAC1 up-regulation and KDM6B down-regulation are associated with active pulmonary tuberculosis disease. Am J Transl Res (2017) 0.75
Population structure and infectious disease risk in southern Africa. Mol Genet Genomics (2017) 0.75
Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics (2004) 125.23
A haplotype map of the human genome. Nature (2005) 105.70
Statistical significance for genomewide studies. Proc Natl Acad Sci U S A (2003) 88.64
Toll-like receptors in the induction of the innate immune response. Nature (2000) 12.23
FASTSNP: an always up-to-date and extendable service for SNP function analysis and prioritization. Nucleic Acids Res (2006) 5.60
Human toll-like receptors mediate cellular activation by Mycobacterium tuberculosis. J Immunol (1999) 4.77
Toll-like receptor 2 controls expansion and function of regulatory T cells. J Clin Invest (2006) 4.72
Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: selective expression of TLR3 in dendritic cells. J Immunol (2000) 4.07
Diagnosis and treatment of tuberculous pleural effusion in 2006. Chest (2007) 2.87
The Arg753GLn polymorphism of the human toll-like receptor 2 gene in tuberculosis disease. Eur Respir J (2004) 2.38
Toll-like receptor 2 as a major gene for asthma in children of European farmers. J Allergy Clin Immunol (2004) 2.10
An association study of asthma and total serum immunoglobin E levels for Toll-like receptor polymorphisms in a Japanese population. Clin Exp Allergy (2004) 2.10
How good are systemic symptoms and blood inflammatory markers at detecting individuals with tuberculosis? Int J Tuberc Lung Dis (2008) 1.79
The 19-kDa Mycobacterium tuberculosis protein induces macrophage apoptosis through Toll-like receptor-2. J Immunol (2003) 1.66
A polymorphism in human TLR2 is associated with increased susceptibility to tuberculous meningitis. Genes Immun (2007) 1.57
The importance of Toll-like receptor 2 polymorphisms in severe infections. Clin Infect Dis (2005) 1.57
Execution of macrophage apoptosis by PE_PGRS33 of Mycobacterium tuberculosis is mediated by Toll-like receptor 2-dependent release of tumor necrosis factor-alpha. J Biol Chem (2006) 1.43
Transcriptional regulation of the human toll-like receptor 2 gene in monocytes and macrophages. J Immunol (2002) 1.40
Toll-like receptor 2 -196 to 174del polymorphism influences the susceptibility of Japanese people to gastric cancer. Cancer Sci (2007) 1.23
The association between microsatellite polymorphisms in intron II of the human Toll-like receptor 2 gene and tuberculosis among Koreans. Genes Immun (2006) 1.21
Human NK cells directly recognize Mycobacterium bovis via TLR2 and acquire the ability to kill monocyte-derived DC. Int Immunol (2008) 1.20
A microsatellite polymorphism in intron 2 of human Toll-like receptor 2 gene: functional implications and racial differences. FEMS Immunol Med Microbiol (2004) 1.14
Mycobacteria induce IFN-gamma production in human dendritic cells via triggering of TLR2. J Immunol (2006) 1.02
Toll-like receptor 2-mediated human B cell differentiation. Clin Immunol (2006) 0.99
Mycobacterium tuberculosis-induced gamma interferon production by natural killer cells requires cross talk with antigen-presenting cells involving Toll-like receptors 2 and 4 and the mannose receptor in tuberculous pleurisy. Infect Immun (2007) 0.99
Genetic polymorphisms of CD14 and Toll-like receptor-2 (TLR2) in patients with ulcerative colitis. J Gastroenterol Hepatol (2007) 0.96
Association between microsatellite polymorphisms in intron II of the human Toll-like receptor 2 gene and nontuberculous mycobacterial lung disease in a Korean population. Hum Immunol (2008) 0.94
TLR2 and TLR4 expression on the immune cells of tuberculous pleural fluid. Immunol Lett (2007) 0.92
Shifts of T4/T8 T lymphocytes from BAL fluid and peripheral blood by clinical grade in patients with pulmonary tuberculosis. Chest (2002) 0.89
Attenuated variants of Lesch-Nyhan disease. Brain (2010) 2.80
Acute respiratory distress syndrome in scrub typhus. Am J Trop Med Hyg (2007) 2.48
Association of a programmed death 1 gene polymorphism with the development of rheumatoid arthritis, but not systemic lupus erythematosus. Arthritis Rheum (2004) 2.18
Living donor liver transplantation: the Asian perspective. Transplantation (2014) 2.13
Extremely elevated CA19-9 in acute cholangitis. Dig Dis Sci (2007) 2.08
Antimicrobial drug-resistant microbes associated with hospitalized community-acquired and healthcare-associated pneumonia: a multi-center study in Taiwan. J Formos Med Assoc (2012) 2.03
Urinary Mycobacterium szulgai infection in an immunocompetent patient. South Med J (2009) 2.02
Neuronal specificity of acupuncture response: a fMRI study with electroacupuncture. Neuroimage (2002) 1.73
Impact of artificial sunlight therapy on the progress of non-alcoholic fatty liver disease in rats. J Hepatol (2010) 1.67
Correlation of pandemic (H1N1) 2009 viral load with disease severity and prolonged viral shedding in children. Emerg Infect Dis (2010) 1.64
Evolution of EV71 genogroup in Taiwan from 1998 to 2005: an emerging of subgenogroup C4 of EV71. J Med Virol (2006) 1.58
Obstructive jaundice alters proliferating cell nuclear antigen expression in rat small intestine. World J Surg (2003) 1.49
Steatosis correlates with hepatic expression of death receptors and activation of nuclear factor-kappaB in chronic hepatitis C. Liver Int (2008) 1.44
Z-LLY-FMK attenuates intestinal apoptosis after bile duct ligation in rats. Dig Dis Sci (2008) 1.41
Tumor necrosis factor-α antagonist therapy for concomitant rheumatoid arthritis and hepatitis C virus infection: a case series study. Clin Rheumatol (2015) 1.39
Comprehensive risk factors, asthma control, and life quality pathways in adults with asthma: A structural equation modeling analysis. Allergy Asthma Proc (2016) 1.38
Differences in clinical and laboratory characteristics and disease severity between children and adults with dengue virus infection in Taiwan, 2002. Trans R Soc Trop Med Hyg (2009) 1.33
FibroScan and ultrasonography in the prediction of hepatic fibrosis in patients with chronic viral hepatitis. J Gastroenterol (2009) 1.27
Laboratory-based surveillance and molecular epidemiology of influenza virus in Taiwan. J Clin Microbiol (2005) 1.26
Purinergic signaling during inflammation. N Engl J Med (2013) 1.25
Dermatofibrosarcoma protuberans of the breast. Tumori (2009) 1.23
Thoracic aortic aneurysm with aortobronchial fistula: a thirteen-year experience. Heart Lung (2004) 1.16
Massive bleeding from an ectopic lingual thyroid follicular adenoma during pregnancy. Am J Otolaryngol (2002) 1.15
Pathologic fracture of the distal femur in osteitis fibrosa cystica simulating metastatic disease. Arch Orthop Trauma Surg (2004) 1.14
Dengue fever with acute acalculous cholecystitis. Am J Trop Med Hyg (2003) 1.14
The role of the cuff leak test in predicting the effects of corticosteroid treatment on postextubation stridor. Chang Gung Med J (2007) 1.14
Normal tension glaucoma in patients with obstructive sleep apnea/hypopnea syndrome. J Glaucoma (2011) 1.14
Associations of a non-synonymous variant in SLC2A9 with gouty arthritis and uric acid levels in Han Chinese subjects and Solomon Islanders. Ann Rheum Dis (2009) 1.11
The cuff-leak test is a simple tool to verify severe laryngeal edema in patients undergoing long-term mechanical ventilation. Crit Care Med (2006) 1.10
Stress response to hepatectomy in patients with a healthy or a diseased liver. World J Surg (2003) 1.10
Cancers Complicating Inflammatory Bowel Disease. N Engl J Med (2015) 1.09
Giant cavernous hemangioma of the liver with coagulopathy: adult Kasabach-Merritt syndrome. Surgery (2007) 1.09
Acute respiratory failure in adult patients with dengue virus infection. Am J Trop Med Hyg (2007) 1.07
Clinical significance of hepatitis B virus (HBV) genotypes and precore and core promoter mutations affecting HBV e antigen expression in Taiwan. J Clin Microbiol (2005) 1.07
Outcome of lung cancer patients with acute respiratory failure requiring mechanical ventilation. Respir Med (2004) 1.06
Decreased retinal nerve fiber layer thickness in patients with obstructive sleep apnea/hypopnea syndrome. Graefes Arch Clin Exp Ophthalmol (2010) 1.06
Immunohistochemical expression of p16INK4A, Ki-67, and Mcm2 proteins in gastrointestinal stromal tumors: prognostic implications and correlations with risk stratification of NIH consensus criteria. Ann Surg Oncol (2006) 1.06
Genetic polymorphisms of viral infection-associated Toll-like receptors in Chinese population. Transl Res (2007) 1.06
Inflammatory Muscle Diseases. N Engl J Med (2015) 1.05
Endobronchial ultrasonography-guided transbronchial needle aspiration increases the diagnostic yield of peripheral pulmonary lesions: a randomized trial. Chest (2008) 1.04
Fine needle aspiration cytodiagnosis of liver tumors. Acta Cytol (2004) 1.04
Malignant diffuse-type tenosynovial giant cell tumors: a series of 7 cases comparing with 24 benign lesions with review of the literature. Am J Surg Pathol (2008) 1.04
Prognostic factors of tracheobronchial mucoepidermoid carcinoma--15 years experience. Respirology (2008) 1.03
Natural course of hepatic focal nodular hyperplasia: a long-term follow-up study with sonography. J Clin Ultrasound (2009) 1.02
Association of mitochondrial deoxyribonucleic acid 16189 variant (T->C transition) with metabolic syndrome in Chinese adults. J Clin Endocrinol Metab (2005) 1.02
Detecting Epstein-Barr virus DNA from peripheral blood mononuclear cells in adult patients with systemic lupus erythematosus in Taiwan. Med Microbiol Immunol (2004) 1.01
Linkage and interaction of loci on 1q23 and 16q12 may contribute to susceptibility to systemic lupus erythematosus. Arthritis Rheum (2002) 1.01
Association of vitamin D receptor gene polymorphism with sporadic breast cancer in Taiwanese patients. Breast Cancer Res Treat (2002) 1.00
Endobronchial ultrasonography with distance for peripheral pulmonary lesions. Respir Med (2006) 0.99
Characterization of liver enzymes on living related liver transplantation patients with acute rejection. Hepatogastroenterology (2005) 0.98
Basaloid squamous cell carcinoma of the sinonasal tract: report of two cases. Otolaryngol Head Neck Surg (2006) 0.98
Link between colorectal cancer and polymorphisms in the uridine-diphosphoglucuronosyltransferase 1A7 and 1A1 genes. World J Gastroenterol (2005) 0.98
Altered p38 mitogen-activated protein kinase expression in different leukocytes with increment of immunosuppressive mediators in patients with severe acute respiratory syndrome. J Immunol (2004) 0.97
Skp2 overexpression is highly representative of intrinsic biological aggressiveness and independently associated with poor prognosis in primary localized myxofibrosarcomas. Clin Cancer Res (2006) 0.97
Homogenous phenomenon of graft liver CYP2C19 genotypes after living donor liver transplantation. Eur J Clin Invest (2011) 0.96
Disseminated liposarcoma in a dog. J Vet Diagn Invest (2005) 0.96
Retroperitoneal mucinous cystadenoma. Dig Dis Sci (2006) 0.95
Influence of CYP2C19 genotypes on graft pathological findings and postoperative liver function in recipients after living-donor liver transplantation. Ann Transplant (2010) 0.95
Molecular signature of clinical severity in recovering patients with severe acute respiratory syndrome coronavirus (SARS-CoV). BMC Genomics (2005) 0.95
Experience of cancer care for metastasis-induced acute pancreatitis patients with lung cancer. J Thorac Oncol (2009) 0.95
Familiality and co-occurrence of clinical features of systemic lupus erythematosus. Arthritis Rheum (2002) 0.95
Serum levels of hepatocyte growth factor in patients with breast cancer. Cancer Epidemiol Biomarkers Prev (2005) 0.95
Diagnostic sensitivity of hepatocellular carcinoma imaging and its application to non-cirrhotic patients. J Gastroenterol Hepatol (2011) 0.95
Right lobe living donor liver transplantation-addressing the middle hepatic vein controversy. Ann Surg (2003) 0.94
Propofol pretreatment attenuates LPS-induced granulocyte-macrophage colony-stimulating factor production in cultured hepatocytes by suppressing MAPK/ERK activity and NF-kappaB translocation. Toxicol Appl Pharmacol (2008) 0.94
Lamivudine for the treatment of hepatitis B virus reactivation following chemotherapy for non-Hodgkin's lymphoma. Br J Haematol (2002) 0.93
Effect of bile acid replacement on endotoxin-induced tumor necrosis factor-alpha production in obstructive jaundice. World J Surg (2002) 0.93
Lipid A fraction of LPS induces a discrete MAPK activation in acute lung injury. Am J Physiol Lung Cell Mol Physiol (2007) 0.93
Prognostic value of signal transducers and activators of transcription 3 in breast cancer. Cancer Epidemiol Biomarkers Prev (2008) 0.93
Ovarian metastasis originating from bronchioloalveolar carcinoma: a rare presentation of lung cancer. Jpn J Clin Oncol (2003) 0.93
Association of Staphylococcus aureus colonization in parturient mothers and their babies. Pediatr Infect Dis J (2009) 0.93
Impact of clinical severity index, infective pathogens, and initial empiric antibiotic use on hospital mortality in patients with ventilator-associated pneumonia. Am J Infect Control (2012) 0.93
Solitary pulmonary nodules differentiated by dynamic F-18 FDG PET in a region with high prevalence of granulomatous disease. J Radiat Res (2012) 0.93
High value of combined serum C-reactive protein and BODE score for mortality prediction in patients with stable COPD. Arch Bronconeumol (2011) 0.92
Esophageal carcinoma. N Engl J Med (2015) 0.91
Massive hemoptysis and hemothorax caused by pleuropulmonary angiosarcoma. Am J Emerg Med (2002) 0.91
Risks of exposure to occupational asthmogens in atopic and nonatopic asthma: a case-control study in Taiwan. Am J Respir Crit Care Med (2010) 0.91
Promoter polymorphism of the CD14 endotoxin receptor gene is associated with biliary atresia and idiopathic neonatal cholestasis. Pediatrics (2005) 0.91
Computed tomographic presentation of mesenteric fibromatosis. Dig Dis Sci (2005) 0.91
Living donor liver transplantation for hepatocellular carcinoma: a single-center experience in Taiwan. Transplantation (2008) 0.91