PubRank

Charles S Redwood

Author PubWeight™ 18.15‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Familial dilated cardiomyopathy caused by an alpha-tropomyosin mutation: the distinctive natural history of sarcomeric dilated cardiomyopathy. J Am Coll Cardiol 2010 1.83
2 Dilated and hypertrophic cardiomyopathy mutations in troponin and alpha-tropomyosin have opposing effects on the calcium affinity of cardiac thin filaments. Circ Res 2007 1.80
3 Mutations in fast skeletal troponin I, troponin T, and beta-tropomyosin that cause distal arthrogryposis all increase contractile function. FASEB J 2006 1.27
4 Myofibrillar Ca(2+) sensitivity is uncoupled from troponin I phosphorylation in hypertrophic obstructive cardiomyopathy due to abnormal troponin T. Cardiovasc Res 2012 0.99
5 Modulation of thin filament activation by breakdown or isoform switching of thin filament proteins: physiological and pathological implications. Circ Res 2003 0.97
6 Mutation analysis of AMP-activated protein kinase subunits in inherited cardiomyopathies: implications for kinase function and disease pathogenesis. J Mol Cell Cardiol 2003 0.97
7 Molecular mechanism of the E99K mutation in cardiac actin (ACTC Gene) that causes apical hypertrophy in man and mouse. J Biol Chem 2011 0.91
8 Conserved noncanonical residue Gly-126 confers instability to the middle part of the tropomyosin molecule. J Biol Chem 2011 0.90
9 DCM troponin C mutant Gly159Asp blunts the response to troponin phosphorylation. Biochem Biophys Res Commun 2007 0.81
10 Functional effects of the DCM mutant Gly159Asp troponin C in skinned muscle fibres. Pflugers Arch 2006 0.81
11 Changes in the cardiac metabolome caused by perhexiline treatment in a mouse model of hypertrophic cardiomyopathy. Mol Biosyst 2015 0.80
12 A revised method of troponin exchange in permeabilised cardiac trabeculae using vanadate: functional consequences of a HCM-causing mutation in troponin I. J Muscle Res Cell Motil 2006 0.79
13 The effect of the dilated cardiomyopathy-causing Glu40Lys TPM1 mutation on actin-myosin interactions during the ATPase cycle. Biochem Biophys Res Commun 2011 0.79
14 Modulation of the effects of tropomyosin on actin and myosin conformational changes by troponin and Ca2+. Biochim Biophys Acta 2008 0.79
15 The effect of the dilated cardiomyopathy-causing mutation Glu54Lys of alpha-tropomyosin on actin-myosin interactions during the ATPase cycle. Arch Biochem Biophys 2009 0.79
16 The effect of the Asp175Asn and Glu180Gly TPM1 mutations on actin-myosin interaction during the ATPase cycle. Biochim Biophys Acta 2011 0.78
17 Dilated cardiomyopathy mutations in alpha-tropomyosin inhibit its movement during the ATPase cycle. Biochem Biophys Res Commun 2009 0.78
18 Effects of troponin C isoform on the action of the cardiotonic agent EMD 57033. Biochem J 2005 0.77
19 Hypertrophic cardiomyopathy-causing Asp175asn and Glu180gly Tpm1 mutations shift tropomyosin strands further towards the open position during the ATPase cycle. Biochem Biophys Res Commun 2011 0.76
20 The nemaline myopathy-causing E117K mutation in β-tropomyosin reduces thin filament activation. Arch Biochem Biophys 2013 0.75