| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Chronic pancreatitis is essential for induction of pancreatic ductal adenocarcinoma by K-Ras oncogenes in adult mice.
|
Cancer Cell
|
2007
|
8.47
|
|
2
|
Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context.
|
Cancer Cell
|
2003
|
5.17
|
|
3
|
Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice.
|
Nat Genet
|
2003
|
4.74
|
|
4
|
Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6.
|
Cell
|
2004
|
4.39
|
|
5
|
Cdk1 is sufficient to drive the mammalian cell cycle.
|
Nature
|
2007
|
4.26
|
|
6
|
A synthetic lethal interaction between K-Ras oncogenes and Cdk4 unveils a therapeutic strategy for non-small cell lung carcinoma.
|
Cancer Cell
|
2010
|
3.97
|
|
7
|
Genomic stability and tumour suppression by the APC/C cofactor Cdh1.
|
Nat Cell Biol
|
2008
|
3.31
|
|
8
|
c-Raf, but not B-Raf, is essential for development of K-Ras oncogene-driven non-small cell lung carcinoma.
|
Cancer Cell
|
2011
|
2.28
|
|
9
|
Helicobacter pylori infection recruits bone marrow-derived cells that participate in gastric preneoplasia in mice.
|
Gastroenterology
|
2011
|
2.13
|
|
10
|
Kallikrein 5 induces atopic dermatitis-like lesions through PAR2-mediated thymic stromal lymphopoietin expression in Netherton syndrome.
|
J Exp Med
|
2009
|
1.83
|
|
11
|
Cdk2 is dispensable for cell cycle inhibition and tumor suppression mediated by p27(Kip1) and p21(Cip1).
|
Cancer Cell
|
2005
|
1.78
|
|
12
|
Genetic rescue of Cdk4 null mice restores pancreatic beta-cell proliferation but not homeostatic cell number.
|
Oncogene
|
2003
|
1.62
|
|
13
|
Inactivation of TIF1gamma cooperates with Kras to induce cystic tumors of the pancreas.
|
PLoS Genet
|
2009
|
1.55
|
|
14
|
Peroxisome proliferator-activated receptor gamma regulates E-cadherin expression and inhibits growth and invasion of prostate cancer.
|
Mol Cell Biol
|
2006
|
1.37
|
|
15
|
Cdk4 promotes adipogenesis through PPARgamma activation.
|
Cell Metab
|
2005
|
1.31
|
|
16
|
Protein farnesyltransferase in embryogenesis, adult homeostasis, and tumor development.
|
Cancer Cell
|
2005
|
1.23
|
|
17
|
PRIME importance of pathology expertise.
|
Nat Biotechnol
|
2009
|
1.19
|
|
18
|
Mantle cell lymphoma-like lymphomas in c-myc-3'RR/p53+/- mice and c-myc-3'RR/Cdk4R24C mice: differential oncogenic mechanisms but similar cellular origin.
|
Oncotarget
|
2012
|
1.17
|
|
19
|
A comparative analysis of FISH, RT-PCR, PCR, and immunohistochemistry for the diagnosis of mantle cell lymphomas.
|
Mod Pathol
|
2002
|
1.11
|
|
20
|
Elastase 2 is expressed in human and mouse epidermis and impairs skin barrier function in Netherton syndrome through filaggrin and lipid misprocessing.
|
J Clin Invest
|
2010
|
1.08
|
|
21
|
CDKN2A-CDKN2B deletion defines an aggressive subset of cutaneous T-cell lymphoma.
|
Mod Pathol
|
2010
|
1.06
|
|
22
|
Mice thrive without Cdk4 and Cdk2.
|
Mol Oncol
|
2007
|
1.02
|
|
23
|
A defect of the INK4-Cdk4 checkpoint and Myc collaborate in blastoid mantle cell lymphoma-like lymphoma formation in mice.
|
Am J Pathol
|
2012
|
0.99
|
|
24
|
Cooperation between Cdk4 and p27kip1 in tumor development: a preclinical model to evaluate cell cycle inhibitors with therapeutic activity.
|
Cancer Res
|
2005
|
0.96
|
|
25
|
Pathology of the laboratory mouse: an International Workshop on Challenges for High Throughput Phenotyping.
|
Toxicol Pathol
|
2011
|
0.95
|
|
26
|
Driving the cell cycle to cancer.
|
Adv Exp Med Biol
|
2003
|
0.93
|
|
27
|
The relative levels of cyclin D1a and D1b alternative transcripts in mantle cell lymphoma may depend more on sample origin than on CCND1 polymorphism.
|
Haematologica
|
2005
|
0.92
|
|
28
|
Transcription factor E4F1 is essential for epidermal stem cell maintenance and skin homeostasis.
|
Proc Natl Acad Sci U S A
|
2010
|
0.92
|
|
29
|
Mucosa-associated lymphoid tissue of the thymus hyperplasia vs lymphoma.
|
Am J Clin Pathol
|
2002
|
0.91
|
|
30
|
Mucosal intraepithelial T-lymphocytes in refractory celiac disease: a neoplastic population with a variable CD8 phenotype.
|
Am J Surg Pathol
|
2008
|
0.90
|
|
31
|
Tif1γ suppresses murine pancreatic tumoral transformation by a Smad4-independent pathway.
|
Am J Pathol
|
2012
|
0.89
|
|
32
|
Interphase fluorescence in situ hybridization is more sensitive than BIOMED-2 polymerase chain reaction protocol in detecting IGH-BCL2 rearrangement in both fixed and frozen lymph node with follicular lymphoma.
|
Hum Pathol
|
2006
|
0.89
|
|
33
|
Loss of epidermal hypoxia-inducible factor-1α accelerates epidermal aging and affects re-epithelialization in human and mouse.
|
J Cell Sci
|
2011
|
0.89
|
|
34
|
Outcome-based determination of optimal pyrosequencing assay for MGMT methylation detection in glioblastoma patients.
|
J Neurooncol
|
2014
|
0.88
|
|
35
|
micro-Opioid receptor activation prevents acute hepatic inflammation and cell death.
|
Gut
|
2007
|
0.86
|
|
36
|
FGFR3 has tumor suppressor properties in cells with epithelial phenotype.
|
Mol Cancer
|
2013
|
0.85
|
|
37
|
Essential role of the N-terminal region of TFII-I in viability and behavior.
|
BMC Med Genet
|
2010
|
0.85
|
|
38
|
Molecular blocking of CD23 supports its role in the pathogenesis of arthritis.
|
PLoS One
|
2009
|
0.85
|
|
39
|
In vivo gene transfer targeting in pancreatic adenocarcinoma with cell surface antigens.
|
Mol Cancer
|
2012
|
0.85
|
|
40
|
E4F1 deficiency results in oxidative stress-mediated cell death of leukemic cells.
|
J Exp Med
|
2011
|
0.85
|
|
41
|
Telomerase functions beyond telomere maintenance in primary cutaneous T-cell lymphoma.
|
Blood
|
2014
|
0.84
|
|
42
|
Inactivation of p16INK4a/CDKN2A gene may be a diagnostic feature of large B cell lymphoma leg type among cutaneous B cell lymphomas.
|
Virchows Arch
|
2008
|
0.83
|
|
43
|
Neoplastic cells do not carry bcl2-JH rearrangements detected in a subset of primary cutaneous follicle center B-cell lymphomas.
|
Am J Surg Pathol
|
2004
|
0.82
|
|
44
|
The RNA-binding protein Unr prevents mouse embryonic stem cells differentiation toward the primitive endoderm lineage.
|
Stem Cells
|
2011
|
0.82
|
|
45
|
Cellular mesoblastic nephroma: morphologic, cytogenetic and molecular links with congenital fibrosarcoma.
|
Pathol Res Pract
|
2003
|
0.81
|
|
46
|
Clinical, histological and molecular follow-up of 60 patients with gastric marginal zone lymphoma of mucosa-associated lymphoid tissue.
|
Virchows Arch
|
2005
|
0.81
|
|
47
|
Metabolic correction of congenital erythropoietic porphyria with iPSCs free of reprogramming factors.
|
Am J Hum Genet
|
2012
|
0.81
|
|
48
|
Variable behavior of iPSCs derived from CML patients for response to TKI and hematopoietic differentiation.
|
PLoS One
|
2013
|
0.81
|
|
49
|
The anti-metastatic nm23-1 gene is needed for the final step of mammary duct maturation of the mouse nipple.
|
PLoS One
|
2011
|
0.80
|
|
50
|
Neonatal bone marrow transplantation prevents liver disease in a murine model of erythropoietic protoporphyria.
|
J Hepatol
|
2010
|
0.78
|
|
51
|
Bone marrow histopathologic and molecular staging in epidermotropic T-cell lymphomas.
|
Am J Clin Pathol
|
2003
|
0.77
|
|
52
|
Primary Lung Small B-Cell Lymphoma versus Lymphoid Hyperplasia: Evaluation of Diagnostic Criteria in 26 Cases.
|
Am J Surg Pathol
|
2002
|
0.77
|
|
53
|
Hepatic lesions observed in hepatitis C virus transgenic mice infected by Helicobacter hepaticus.
|
Helicobacter
|
2012
|
0.77
|
|
54
|
Genetic characterization of the role of the Cip/Kip family of proteins as cyclin-dependent kinase inhibitors and assembly factors.
|
Mol Cell Biol
|
2014
|
0.76
|
|
55
|
An Eighteen-Month Helicobacter Infection Does Not Induce Amyloid Plaques or Neuroinflammation in Brains of Wild Type C57BL/6J Mice.
|
J Alzheimers Dis
|
2015
|
0.76
|
|
56
|
CDK4 is an essential insulin effector in adipocytes.
|
J Clin Invest
|
2015
|
0.75
|
|
57
|
[Composite lymphoma: association of a follicular lymphoma and a chronic lymphocytic leukemia].
|
Ann Pathol
|
2008
|
0.75
|
|
58
|
[The mouse as preclinical models of lung cancer].
|
Bull Cancer
|
2012
|
0.75
|
|
59
|
[CDK4, a specific target in the treatment of lung adenocarcinomas mutated for KRAS].
|
Med Sci (Paris)
|
2010
|
0.75
|
|
60
|
A solitary minute thyroid lymphoma of MALT-type without lymphoid thyroiditis.
|
Endocr Pathol
|
2002
|
0.75
|
|
61
|
Sequential development of Hodgkin's disease and CD30+ diffuse large B-cell lymphoma in a patient with MALT-type lymphoma: evidence of different clonal origin of single microdissected Reed-Sternberg cells.
|
Am J Surg Pathol
|
2002
|
0.75
|
|
62
|
[CRAF, a key player in lung adenocarcinomas induced by K-Ras oncogene].
|
Med Sci (Paris)
|
2011
|
0.75
|
|
63
|
[Interphase FISH analysis on histologic sections of fixed tissues for t(11;14) (q13;q32) detection in mantle cell lymphoma and t(8;14)(q24;q32) in Burkitt's lymphoma].
|
Ann Pathol
|
2002
|
0.75
|