PubRank

Witold K Surewicz

Author PubWeight™ 51.96‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Mammalian prions generated from bacterially expressed prion protein in the absence of any mammalian cofactors. J Biol Chem 2010 2.57
2 Molecular architecture of human prion protein amyloid: a parallel, in-register beta-structure. Proc Natl Acad Sci U S A 2007 2.55
3 Molecular basis of barriers for interspecies transmissibility of mammalian prions. Mol Cell 2004 2.39
4 Beta-sheet core of human prion protein amyloid fibrils as determined by hydrogen/deuterium exchange. Proc Natl Acad Sci U S A 2007 2.14
5 Fibril conformation as the basis of species- and strain-dependent seeding specificity of mammalian prion amyloids. Cell 2005 2.06
6 Structural organization of brain-derived mammalian prions examined by hydrogen-deuterium exchange. Nat Struct Mol Biol 2011 1.90
7 Interaction between human prion protein and amyloid-beta (Abeta) oligomers: role OF N-terminal residues. J Biol Chem 2010 1.88
8 Molecular conformation and dynamics of the Y145Stop variant of human prion protein in amyloid fibrils. Proc Natl Acad Sci U S A 2008 1.86
9 Prion diseases and their biochemical mechanisms. Biochemistry 2009 1.65
10 PrP conformational transitions alter species preference of a PrP-specific antibody. J Biol Chem 2010 1.62
11 Conformational flexibility of Y145Stop human prion protein amyloid fibrils probed by solid-state nuclear magnetic resonance spectroscopy. J Am Chem Soc 2010 1.55
12 The effect of disease-associated mutations on the folding pathway of human prion protein. J Biol Chem 2004 1.34
13 Distinct structures of scrapie prion protein (PrPSc)-seeded versus spontaneous recombinant prion protein fibrils revealed by hydrogen/deuterium exchange. J Biol Chem 2009 1.27
14 Polymorphism at residue 129 modulates the conformational conversion of the D178N variant of human prion protein 90-231. Biochemistry 2005 1.21
15 Nucleation-dependent conformational conversion of the Y145Stop variant of human prion protein: structural clues for prion propagation. Proc Natl Acad Sci U S A 2003 1.14
16 Kinetic intermediate in the folding of human prion protein. J Biol Chem 2002 1.13
17 Intermolecular alignment in Y145Stop human prion protein amyloid fibrils probed by solid-state NMR spectroscopy. J Am Chem Soc 2011 1.10
18 Early intermediate in human prion protein folding as evidenced by ultrarapid mixing experiments. J Am Chem Soc 2006 1.09
19 Disease-associated F198S mutation increases the propensity of the recombinant prion protein for conformational conversion to scrapie-like form. J Biol Chem 2002 1.08
20 Small protease sensitive oligomers of PrPSc in distinct human prions determine conversion rate of PrP(C). PLoS Pathog 2012 1.07
21 Conformational diversity in prion protein variants influences intermolecular beta-sheet formation. EMBO J 2009 1.07
22 Molecular biology and pathology of prion strains in sporadic human prion diseases. Acta Neuropathol 2010 1.06
23 The role of glycophosphatidylinositol anchor in the amplification of the scrapie isoform of prion protein in vitro. FEBS Lett 2009 1.04
24 Atypical effect of salts on the thermodynamic stability of human prion protein. J Biol Chem 2003 1.03
25 Prion protein amyloid formation under native-like conditions involves refolding of the C-terminal alpha-helical domain. J Biol Chem 2008 1.02
26 Soluble prion protein inhibits amyloid-β (Aβ) fibrillization and toxicity. J Biol Chem 2012 0.96
27 Crystal structure of a human prion protein fragment reveals a motif for oligomer formation. J Am Chem Soc 2013 0.94
28 Role of N-terminal familial mutations in prion protein fibrillization and prion amyloid propagation in vitro. J Biol Chem 2006 0.93
29 Functional interactions of nucleocapsid protein of feline immunodeficiency virus and cellular prion protein with the viral RNA. J Mol Biol 2002 0.93
30 Conformational stability of mammalian prion protein amyloid fibrils is dictated by a packing polymorphism within the core region. J Biol Chem 2013 0.92
31 Antimicrobial activity of human prion protein is mediated by its N-terminal region. PLoS One 2009 0.90
32 Structural polymorphism in amyloids: new insights from studies with Y145Stop prion protein fibrils. J Biol Chem 2011 0.89
33 Cellular prion protein regulates its own α-cleavage through ADAM8 in skeletal muscle. J Biol Chem 2012 0.88
34 Cellular oxidant stress and advanced glycation endproducts of albumin: caveats of the dichlorofluorescein assay. Arch Biochem Biophys 2002 0.87
35 Mechanism of stabilization of Bacillus circulans xylanase upon the introduction of disulfide bonds. Biophys Chem 2006 0.84
36 Nanomechanical properties of human prion protein amyloid as probed by force spectroscopy. Biophys J 2008 0.82
37 Recombinant human prion protein inhibits prion propagation in vitro. Sci Rep 2013 0.82
38 The effect of β2-α2 loop mutation on amyloidogenic properties of the prion protein. FEBS Lett 2013 0.79
39 Interaction between prion protein and Aβ amyloid fibrils revisited. ACS Chem Neurosci 2014 0.78
40 Prion strains under the magnifying glass. Nat Struct Mol Biol 2007 0.77
41 Thermodynamic stabilization of the folded domain of prion protein inhibits prion infection in vivo. Cell Rep 2013 0.77
42 Structural underpinnings of prion protein conversion. J Biol Chem 2011 0.75
43 Protein science: discriminating taste of prions. Nature 2007 0.75