PubRank

Ni Ai

Author PubWeight™ 22.83‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines. Cancer Res 2003 3.72
2 Bisphenol A and its analogues activate human pregnane X receptor. Environ Health Perspect 2012 1.81
3 Lack of androgenicity and estrogenicity of the three monomers used in Eastman's Tritan™ copolyesters. Food Chem Toxicol 2012 1.76
4 Human pregnane X receptor antagonists and agonists define molecular requirements for different binding sites. Mol Pharmacol 2007 1.39
5 Evolving carbapenemases: can medicinal chemists advance one step ahead of the coming storm? J Med Chem 2010 1.09
6 Evolution of the bile salt nuclear receptor FXR in vertebrates. J Lipid Res 2008 1.08
7 Ligand specificity and evolution of liver X receptors. J Steroid Biochem Mol Biol 2008 1.06
8 Inhibition of human liver catechol-O-methyltransferase by tea catechins and their metabolites: structure-activity relationship and molecular-modeling studies. Biochem Pharmacol 2005 1.04
9 Computational discovery of novel low micromolar human pregnane X receptor antagonists. Mol Pharmacol 2008 0.98
10 Potent inhibitors of human organic anion transporters 1 and 3 from clinical drug libraries: discovery and molecular characterization. Mol Pharm 2012 0.89
11 Identification of previously unrecognized antiestrogenic chemicals using a novel virtual screening approach. Chem Res Toxicol 2006 0.89
12 The evolution of farnesoid X, vitamin D, and pregnane X receptors: insights from the green-spotted pufferfish (Tetraodon nigriviridis) and other non-mammalian species. BMC Biochem 2011 0.89
13 The major human pregnane X receptor (PXR) splice variant, PXR.2, exhibits significantly diminished ligand-activated transcriptional regulation. Drug Metab Dispos 2009 0.87
14 Relating anatomical therapeutic indications by the ensemble similarity of drug sets. J Chem Inf Model 2013 0.82
15 LTMap: a web server for assessing the potential liver toxicity by genome-wide transcriptional expression data. J Appl Toxicol 2013 0.82
16 Progenetix: 12 years of oncogenomic data curation. Nucleic Acids Res 2013 0.82
17 Pregnane X receptor mediates dyslipidemia induced by the HIV protease inhibitor amprenavir in mice. Mol Pharmacol 2013 0.81
18 Two farnesoid X receptor alpha isoforms in Japanese medaka (Oryzias latipes) are differentially activated in vitro. Aquat Toxicol 2010 0.81
19 Dissecting active ingredients of Chinese medicine by content-weighted ingredient-target network. Mol Biosyst 2014 0.81
20 Human ADA3 regulates RARalpha transcriptional activity through direct contact between LxxLL motifs and the receptor coactivator pocket. Nucleic Acids Res 2010 0.81
21 Benzotropolone inhibitors of estradiol methylation: kinetics and in silico modeling studies. Bioorg Med Chem 2005 0.75
22 Dissecting functional chemome of Xiaoqinglong decoction analogous formulae using network formulaology approach. Zhongguo Zhong Yao Za Zhi 2015 0.75
23 [Toxicogenomics and its application in safety evaluation of traditional Chinese medicine]. Zhongguo Zhong Yao Za Zhi 2015 0.75
24 Network-based Assessment on Chemical-induced Cholestatic Liver Injury. Curr Top Med Chem 2016 0.75