Published in J Neurotrauma on May 01, 2010
Microglial activation induced by brain trauma is suppressed by post-injury treatment with a PARP inhibitor. J Neuroinflammation (2012) 1.22
Neurotransmitter signaling in the pathophysiology of microglia. Front Cell Neurosci (2013) 0.98
Molecular probes for the A2A adenosine receptor based on a pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine scaffold. Bioorg Med Chem Lett (2010) 0.97
Expression of the 2',3'-cAMP-adenosine pathway in astrocytes and microglia. J Neurochem (2011) 0.95
Adenosine augments IL-10 production by microglial cells through an A2B adenosine receptor-mediated process. J Immunol (2011) 0.94
Mechanical stimulation evokes rapid increases in extracellular adenosine concentration in the prefrontal cortex. J Neurochem (2014) 0.92
The brain in vivo expresses the 2',3'-cAMP-adenosine pathway. J Neurochem (2012) 0.92
Temporal patterns of cortical proliferation of glial cell populations after traumatic brain injury in mice. ASN Neuro (2014) 0.87
Emerging therapies in traumatic brain injury. Semin Neurol (2015) 0.86
Treatment of mild traumatic brain injury with an erythropoietin-mimetic peptide. J Neurotrauma (2012) 0.85
2',3'-cAMP, 3'-AMP, 2'-AMP and adenosine inhibit TNF-α and CXCL10 production from activated primary murine microglia via A2A receptors. Brain Res (2014) 0.83
Role of A1 receptors in renal sympathetic neurotransmission in the mouse kidney. Am J Physiol Renal Physiol (2012) 0.82
Role of microglia adenosine A(2A) receptors in retinal and brain neurodegenerative diseases. Mediators Inflamm (2014) 0.80
Stuck at the bench: Potential natural neuroprotective compounds for concussion. Surg Neurol Int (2011) 0.78
Guanosine inhibits LPS-induced pro-inflammatory response and oxidative stress in hippocampal astrocytes through the heme oxygenase-1 pathway. Purinergic Signal (2015) 0.78
Adenosine kinase facilitated astrogliosis-induced cortical neuronal death in traumatic brain injury. J Mol Histol (2016) 0.77
Different analgesic effects of adenosine between postoperative and neuropathic pain. J Orthop Sci (2012) 0.75
Adenosine production by brain cells. J Neurochem (2017) 0.75
Acetate supplementation modulates brain adenosine metabolizing enzymes and adenosine A₂A receptor levels in rats subjected to neuroinflammation. J Neuroinflammation (2014) 0.75
Mini Review of Controlled Cortical Impact: A Well-Suited Device for Concussion Research. Brain Sci (2017) 0.75
Microglia: active sensor and versatile effector cells in the normal and pathologic brain. Nat Neurosci (2007) 11.11
Immortalization of murine microglial cells by a v-raf/v-myc carrying retrovirus. J Neuroimmunol (1990) 4.37
Selective ablation of proliferating microglial cells exacerbates ischemic injury in the brain. J Neurosci (2007) 3.93
Nonconvulsive electrographic seizures after traumatic brain injury result in a delayed, prolonged increase in intracranial pressure and metabolic crisis. Crit Care Med (2007) 3.08
Mediation of tubuloglomerular feedback by adenosine: evidence from mice lacking adenosine 1 receptors. Proc Natl Acad Sci U S A (2001) 2.65
Enhanced expression of Iba1, ionized calcium-binding adapter molecule 1, after transient focal cerebral ischemia in rat brain. Stroke (2001) 2.51
Spatial and temporal characteristics of neurodegeneration after controlled cortical impact in mice: more than a focal brain injury. J Neurotrauma (2005) 2.03
Evolution of post-traumatic neurodegeneration after controlled cortical impact traumatic brain injury in mice and rats as assessed by the de Olmos silver and fluorojade staining methods. J Neurotrauma (2008) 1.67
A1 adenosine receptor upregulation and activation attenuates neuroinflammation and demyelination in a model of multiple sclerosis. J Neurosci (2004) 1.66
Magnetic resonance imaging assessment of macrophage accumulation in mouse brain after experimental traumatic brain injury. J Neurotrauma (2009) 1.60
Adenosine A1 receptors are crucial in keeping an epileptic focus localized. Exp Neurol (2006) 1.40
Physiological and structural evidence for hippocampal involvement in persistent seizure susceptibility after traumatic brain injury. J Neurosci (2001) 1.39
Adenosine A1 receptor knockout mice develop lethal status epilepticus after experimental traumatic brain injury. J Cereb Blood Flow Metab (2006) 1.37
Microglia in cerebral ischemia: molecular actions and interactions. Can J Physiol Pharmacol (2006) 1.36
Status epilepticus induces a particular microglial activation state characterized by enhanced purinergic signaling. J Neurosci (2008) 1.35
Experimental model of pediatric asphyxial cardiopulmonary arrest in rats. Pediatr Crit Care Med (2004) 1.24
Enhanced oxidative stress in iNOS-deficient mice after traumatic brain injury: support for a neuroprotective role of iNOS. J Cereb Blood Flow Metab (2005) 1.23
Inducible nitric oxide synthase is an endogenous neuroprotectant after traumatic brain injury in rats and mice. J Clin Invest (1999) 1.21
Traumatic brain injury in the immature mouse brain: characterization of regional vulnerability. Exp Neurol (2002) 1.17
Modulation of glial cell functions by adenosine receptors. Physiol Behav (2007) 1.09
Chronic but not acute treatment with caffeine attenuates traumatic brain injury in the mouse cortical impact model. Neuroscience (2007) 1.04
Adenosine modulates transmission at the hippocampal mossy fibre synapse via direct inhibition of presynaptic calcium channels. J Physiol (2007) 1.03
Evidence for functional adenosine A3 receptors in microglia cells. J Neurochem (2003) 1.01
A1 adenosine receptors in microglia control glioblastoma-host interaction. Cancer Res (2006) 0.99
Isoquinoline and quinazoline urea analogues as antagonists for the human adenosine A(3) receptor. J Med Chem (2000) 0.97
Seizures accelerate anoxia-induced neuronal death in the neonatal rat hippocampus. Ann Neurol (2000) 0.95
Combination of low dose ethanol and caffeine protects brain from damage produced by focal ischemia in rats. Neuropharmacology (2000) 0.95
Deletion of the adenosine A1 receptor gene does not alter neuronal damage following ischaemia in vivo or in vitro. Eur J Neurosci (2004) 0.94
Mice lacking the adenosine A1 receptor have normal spatial learning and plasticity in the CA1 region of the hippocampus, but they habituate more slowly. Synapse (2005) 0.91
Adenosine and propentofylline inhibit the proliferation of cultured microglial cells. Exp Neurol (1996) 0.89
Administration of adenosine receptor agonists or antagonists after controlled cortical impact in mice: effects on function and histopathology. Brain Res (2002) 0.89
Both adenosine A1- and A2-receptors are required to stimulate microglial proliferation. Neurochem Int (1996) 0.89
ATP and adenosine induce ramification of microglia in vitro. J Neuroimmunol (2001) 0.86
Increases in cerebrospinal fluid caffeine concentration are associated with favorable outcome after severe traumatic brain injury in humans. J Cereb Blood Flow Metab (2007) 0.81
A proteomics approach to understanding protein ubiquitination. Nat Biotechnol (2003) 10.51
Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation. Cell (2009) 6.16
Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents--second edition. Pediatr Crit Care Med (2012) 4.65
Clinical trials in head injury. J Neurotrauma (2002) 4.34
A2A adenosine receptor protects tumors from antitumor T cells. Proc Natl Acad Sci U S A (2006) 4.25
Adenosine A1 receptors mediate local anti-nociceptive effects of acupuncture. Nat Neurosci (2010) 3.38
Innate gender-based proclivity in response to cytotoxicity and programmed cell death pathway. J Biol Chem (2004) 3.06
Semiquantitative proteomic analysis of rat forebrain postsynaptic density fractions by mass spectrometry. J Biol Chem (2004) 2.84
IL-1β associations with posttraumatic epilepsy development: a genetics and biomarker cohort study. Epilepsia (2014) 2.59
Adenosine is crucial for deep brain stimulation-mediated attenuation of tremor. Nat Med (2007) 2.59
Prolyl 4-hydroxylation regulates Argonaute 2 stability. Nature (2008) 2.51
Major contribution of tubular secretion to creatinine clearance in mice. Kidney Int (2009) 2.46
Incidence of postoperative hyponatremia and complications in critically-ill children treated with hypotonic and normotonic solutions. J Pediatr (2007) 2.42
Inhaled anesthetics and immobility: mechanisms, mysteries, and minimum alveolar anesthetic concentration. Anesth Analg (2003) 2.41
Analysis of the large inactive P-TEFb complex indicates that it contains one 7SK molecule, a dimer of HEXIM1 or HEXIM2, and two P-TEFb molecules containing Cdk9 phosphorylated at threonine 186. J Biol Chem (2005) 2.24
A new naturally occurring GABA(A) receptor subunit partnership with high sensitivity to ethanol. Nat Neurosci (2006) 2.21
Generation and accumulation of immunosuppressive adenosine by human CD4+CD25highFOXP3+ regulatory T cells. J Biol Chem (2009) 2.18
Impairment of tubuloglomerular feedback regulation of GFR in ecto-5'-nucleotidase/CD73-deficient mice. J Clin Invest (2004) 2.12
GABA(A) receptor changes in delta subunit-deficient mice: altered expression of alpha4 and gamma2 subunits in the forebrain. J Comp Neurol (2002) 2.11
Acute care clinical indicators associated with discharge outcomes in children with severe traumatic brain injury. Crit Care Med (2014) 2.04
Intra-mitochondrial poly(ADP-ribosylation) contributes to NAD+ depletion and cell death induced by oxidative stress. J Biol Chem (2003) 2.04
AT1A angiotensin receptors in the renal proximal tubule regulate blood pressure. Cell Metab (2011) 2.03
Autophosphorylated CaMKIIalpha acts as a scaffold to recruit proteasomes to dendritic spines. Cell (2010) 2.02
Cytochrome c/cardiolipin relations in mitochondria: a kiss of death. Free Radic Biol Med (2009) 2.00
Serum neuron-specific enolase, S100B, and myelin basic protein concentrations after inflicted and noninflicted traumatic brain injury in children. J Neurosurg (2005) 1.99
Neurological sequelae of 2009 influenza A (H1N1) in children: a case series observed during a pandemic. Pediatr Crit Care Med (2010) 1.95
Thrombospondin-1 supports blood pressure by limiting eNOS activation and endothelial-dependent vasorelaxation. Cardiovasc Res (2010) 1.91
Functional expression of the olfactory signaling system in the kidney. Proc Natl Acad Sci U S A (2009) 1.90
A tertiary care center's experience with therapeutic hypothermia after pediatric cardiac arrest. Pediatr Crit Care Med (2010) 1.90
Regulation of renin in mice with Cre recombinase-mediated deletion of G protein Gsalpha in juxtaglomerular cells. Am J Physiol Renal Physiol (2006) 1.86
Critical time window for intra-arrest cooling with cold saline flush in a dog model of cardiopulmonary resuscitation. Circulation (2006) 1.84
Neuronal adenosine release, and not astrocytic ATP release, mediates feedback inhibition of excitatory activity. Proc Natl Acad Sci U S A (2012) 1.74
Sex hormones and hypertension. Cardiovasc Res (2002) 1.74
Human LSD2/KDM1b/AOF1 regulates gene transcription by modulating intragenic H3K4me2 methylation. Mol Cell (2010) 1.73
Micropuncture determination of nephron function in mice without tissue angiotensin-converting enzyme. Am J Physiol Renal Physiol (2004) 1.73
Neurological injury markers in children with septic shock. Pediatr Crit Care Med (2008) 1.71
Blast exposure in rats with body shielding is characterized primarily by diffuse axonal injury. J Neurotrauma (2011) 1.71
2-Methoxyestradiol, an estradiol metabolite, inhibits neointima formation and smooth muscle cell growth via double blockade of the cell cycle. Circ Res (2006) 1.70
Therapeutic hypothermia preserves antioxidant defenses after severe traumatic brain injury in infants and children. Crit Care Med (2009) 1.70
Ecto-5'-nucleotidase deficiency exacerbates pressure-overload-induced left ventricular hypertrophy and dysfunction. Hypertension (2008) 1.70
Adenosine production by human B cells and B cell-mediated suppression of activated T cells. Blood (2013) 1.70
Guideline Adherence and Hospital Costs in Pediatric Severe Traumatic Brain Injury. Pediatr Crit Care Med (2016) 1.69
Increases in serum levels of troponin I are associated with cardiac dysfunction and disease severity in pediatric patients with septic shock. Pediatr Crit Care Med (2004) 1.69
Urinary S100B concentrations are increased after brain injury in children: A preliminary study. Pediatr Crit Care Med (2006) 1.68
Induced hyperthermia exacerbates neurologic neuronal histologic damage after asphyxial cardiac arrest in rats. Crit Care Med (2003) 1.68
Spatiotemporal specificity of GABAA receptor-mediated regulation of adult hippocampal neurogenesis. Eur J Neurosci (2011) 1.68
Nuclear Akt associates with PKC-phosphorylated Ebp1, preventing DNA fragmentation by inhibition of caspase-activated DNase. EMBO J (2006) 1.67
A1 adenosine receptor upregulation and activation attenuates neuroinflammation and demyelination in a model of multiple sclerosis. J Neurosci (2004) 1.66
Increased ectonucleotidase expression and activity in regulatory T cells of patients with head and neck cancer. Clin Cancer Res (2009) 1.66
Intracranial pressure-monitoring systems in children with traumatic brain injury: combining therapeutic and diagnostic tools. Pediatr Crit Care Med (2011) 1.65
Molecular determinants of polyubiquitin linkage selection by an HECT ubiquitin ligase. EMBO J (2006) 1.64
Mild hypothermia during prolonged cardiopulmonary cerebral resuscitation increases conscious survival in dogs. Crit Care Med (2004) 1.62
Magnetic resonance imaging assessment of macrophage accumulation in mouse brain after experimental traumatic brain injury. J Neurotrauma (2009) 1.60
Therapeutic hypothermia-induced pharmacokinetic alterations on CYP2E1 chlorzoxazone-mediated metabolism in a cardiac arrest rat model. Crit Care Med (2006) 1.59
Dual mechanism of brain injury and novel treatment strategy in maple syrup urine disease. Brain (2009) 1.59
Gabrb3 gene deficient mice exhibit impaired social and exploratory behaviors, deficits in non-selective attention and hypoplasia of cerebellar vermal lobules: a potential model of autism spectrum disorder. Behav Brain Res (2007) 1.58
Proteomic characterization of postmortem amyloid plaques isolated by laser capture microdissection. J Biol Chem (2004) 1.58
Lipidomics identifies cardiolipin oxidation as a mitochondrial target for redox therapy of brain injury. Nat Neurosci (2012) 1.58
Functional consequences of GABAA receptor alpha 4 subunit deletion on synaptic and extrasynaptic currents in mouse dentate granule cells. Alcohol Clin Exp Res (2007) 1.57
Extracorporeal versus conventional cardiopulmonary resuscitation after ventricular fibrillation cardiac arrest in rats: a feasibility trial. Crit Care Med (2013) 1.57
Contribution of the basolateral isoform of the Na-K-2Cl- cotransporter (NKCC1/BSC2) to renin secretion. Am J Physiol Renal Physiol (2005) 1.57
Mild hypothermia decreases fentanyl and midazolam steady-state clearance in a rat model of cardiac arrest. Crit Care Med (2012) 1.57
Brain injuries and neurological system failure are the most common proximate causes of death in children admitted to a pediatric intensive care unit. Pediatr Crit Care Med (2011) 1.56
Polynitroxylated pegylated hemoglobin: a novel neuroprotective hemoglobin for acute volume-limited fluid resuscitation after combined traumatic brain injury and hemorrhagic hypotension in mice. Crit Care Med (2011) 1.54
Effects of hypothermia on drug disposition, metabolism, and response: A focus of hypothermia-mediated alterations on the cytochrome P450 enzyme system. Crit Care Med (2007) 1.53
Intranuclear localization of apoptosis-inducing factor (AIF) and large scale DNA fragmentation after traumatic brain injury in rats and in neuronal cultures exposed to peroxynitrite. J Neurochem (2002) 1.52
Survival without brain damage after clinical death of 60-120 mins in dogs using suspended animation by profound hypothermia. Crit Care Med (2003) 1.52
Effects of adenosine deaminase and A1 receptor deficiency in normoxic and ischaemic mouse hearts. Cardiovasc Res (2006) 1.52
Serum biomarkers of brain injury to classify outcome after pediatric cardiac arrest*. Crit Care Med (2014) 1.52
Therapeutic hypothermia decreases phenytoin elimination in children with traumatic brain injury. Crit Care Med (2013) 1.51
Renal phenotype of UT-A urea transporter knockout mice. J Am Soc Nephrol (2005) 1.51
Vascular consequences of menopause and hormone therapy: importance of timing of treatment and type of estrogen. Cardiovasc Res (2005) 1.51
Moderate hypothermia prevents cardiac arrest-mediated suppression of drug metabolism and induction of interleukin-6 in rats. Crit Care Med (2009) 1.49
Bench-to-bedside review: Apoptosis/programmed cell death triggered by traumatic brain injury. Crit Care (2004) 1.49
Starving neurons show sex difference in autophagy. J Biol Chem (2008) 1.49
Dysautonomia after pediatric brain injury. Dev Med Child Neurol (2012) 1.49
Cold aortic flush and chest compressions enable good neurologic outcome after 15 mins of ventricular fibrillation in cardiac arrest in pigs. Crit Care Med (2010) 1.48
National variability in intracranial pressure monitoring and craniotomy for children with moderate to severe traumatic brain injury. Neurosurgery (2013) 1.48
Attenuated renovascular constrictor responses to angiotensin II in adenosine 1 receptor knockout mice. Am J Physiol Regul Integr Comp Physiol (2003) 1.48
Polyubiquitin linkage profiles in three models of proteolytic stress suggest the etiology of Alzheimer disease. J Biol Chem (2011) 1.48
Systematic approach for validating the ubiquitinated proteome. Anal Chem (2008) 1.47
Therapeutic hypothermia after cardiac arrest. N Engl J Med (2002) 1.46
Winning the cold war: inroads into implementation of mild hypothermia after cardiac arrest in adults from the European Resuscitation Council Hypothermia After Cardiac Arrest Registry Study Group. Crit Care Med (2007) 1.46
Emergency preservation and delayed resuscitation allows normal recovery after exsanguination cardiac arrest in rats: a feasibility trial. Crit Care Med (2007) 1.46
Brain tissue oxygen monitoring after severe traumatic brain injury in children: relationship to outcome and association with other clinical parameters. J Neurosurg Pediatr (2012) 1.45