PubRank

Marc F Hoylaerts

Author PubWeight™ 95.11‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The uremic retention solute p-cresyl sulfate and markers of endothelial damage. Am J Kidney Dis 2009 2.34
2 A functional genomics approach reveals novel quantitative trait loci associated with platelet signaling pathways. Blood 2009 2.25
3 Diesel exhaust particles in lung acutely enhance experimental peripheral thrombosis. Circulation 2003 2.12
4 Ultrafine particles affect experimental thrombosis in an in vivo hamster model. Am J Respir Crit Care Med 2002 2.06
5 Novel inhibitors of alkaline phosphatase suppress vascular smooth muscle cell calcification. J Bone Miner Res 2007 1.92
6 Gas6 promotes inflammation by enhancing interactions between endothelial cells, platelets, and leukocytes. Blood 2007 1.86
7 Possible mechanisms of the cardiovascular effects of inhaled particles: systemic translocation and prothrombotic effects. Toxicol Lett 2004 1.70
8 Pharmacological inhibition of PHOSPHO1 suppresses vascular smooth muscle cell calcification. J Bone Miner Res 2013 1.60
9 Role of Gas6 receptors in platelet signaling during thrombus stabilization and implications for antithrombotic therapy. J Clin Invest 2005 1.55
10 Progression of the prothrombotic state in aging Bmal1-deficient mice. Arterioscler Thromb Vasc Biol 2011 1.43
11 Elevated skeletal osteopontin levels contribute to the hypophosphatasia phenotype in Akp2(-/-) mice. J Bone Miner Res 2006 1.39
12 Residues determining the binding specificity of uncompetitive inhibitors to tissue-nonspecific alkaline phosphatase. J Bone Miner Res 2004 1.36
13 Thrombospondin-1 controls vascular platelet recruitment and thrombus adherence in mice by protecting (sub)endothelial VWF from cleavage by ADAMTS13. Blood 2005 1.35
14 Endothelial von Willebrand factor recruits platelets to atherosclerosis-prone sites in response to hypercholesterolemia. Blood 2002 1.33
15 Acute toxicity and prothrombotic effects of quantum dots: impact of surface charge. Environ Health Perspect 2008 1.32
16 Size effect of intratracheally instilled particles on pulmonary inflammation and vascular thrombosis. Toxicol Appl Pharmacol 2003 1.30
17 Pulmonary inflammation and thrombogenicity caused by diesel particles in hamsters: role of histamine. Am J Respir Crit Care Med 2003 1.29
18 Kinetic analysis of substrate utilization by native and TNAP-, NPP1-, or PHOSPHO1-deficient matrix vesicles. J Bone Miner Res 2010 1.29
19 Pharmacological stabilization of mast cells abrogates late thrombotic events induced by diesel exhaust particles in hamsters. Circulation 2004 1.25
20 Overexpression of the platelet P2X1 ion channel in transgenic mice generates a novel prothrombotic phenotype. Blood 2003 1.21
21 Platelet JNK1 is involved in secretion and thrombus formation. Blood 2010 1.20
22 Kinetic characterization of hypophosphatasia mutations with physiological substrates. J Bone Miner Res 2002 1.19
23 Effects of particulate air pollution on hemostasis. Clin Occup Environ Med 2006 1.14
24 A novel mechanism of sustained platelet αIIbβ3 activation via PEAR1. Blood 2012 1.12
25 Functional polymorphisms in the paternally expressed XLalphas and its cofactor ALEX decrease their mutual interaction and enhance receptor-mediated cAMP formation. Hum Mol Genet 2003 1.12
26 Involvement of the mitogen-activated protein kinase c-Jun NH2-terminal kinase 1 in thrombus formation. J Biol Chem 2007 1.12
27 Air pollution related prothrombotic changes in persons with diabetes. Environ Health Perspect 2010 1.11
28 A novel phosphatase upregulated in Akp3 knockout mice. Am J Physiol Gastrointest Liver Physiol 2007 1.09
29 Thrombospondin-1 deficiency accelerates atherosclerotic plaque maturation in ApoE-/- mice. Circ Res 2008 1.08
30 Lack of plasminogen activator inhibitor-1 promotes growth and abnormal matrix remodeling of advanced atherosclerotic plaques in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol 2002 1.05
31 Different substitutions at residue D218 of the X-linked transcription factor GATA1 lead to altered clinical severity of macrothrombocytopenia and anemia and are associated with variable skewed X inactivation. Hum Mol Genet 2002 1.03
32 Thrombogenicity of beta 2-glycoprotein I-dependent antiphospholipid antibodies in a photochemically induced thrombosis model in the hamster. Blood 2002 1.03
33 Function assignment to conserved residues in mammalian alkaline phosphatases. J Biol Chem 2002 1.00
34 The pituitary adenylate cyclase-activating polypeptide is a physiological inhibitor of platelet activation. J Clin Invest 2004 0.99
35 Proteoliposomes harboring alkaline phosphatase and nucleotide pyrophosphatase as matrix vesicle biomimetics. J Biol Chem 2010 0.96
36 Activation of alphaIIbbeta3 is a sufficient but also an imperative prerequisite for activation of alpha2beta1 on platelets. Blood 2006 0.95
37 Differential Involvement of ERK2 and p38 in platelet adhesion to collagen. J Biol Chem 2005 0.95
38 Thrombospondin-1 activates medial smooth muscle cells and triggers neointima formation upon mouse carotid artery ligation. Arterioscler Thromb Vasc Biol 2007 0.95
39 Impact of clock gene Bmal1 deficiency on nutritionally induced obesity in mice. Obesity (Silver Spring) 2010 0.95
40 Platelets, thrombospondin-1 and human dermal fibroblasts cooperate for stimulation of endothelial cell tubulogenesis through VEGF and PAI-1 regulation. Exp Cell Res 2006 0.94
41 Silica particles enhance peripheral thrombosis: key role of lung macrophage-neutrophil cross-talk. Am J Respir Crit Care Med 2005 0.93
42 Fibrin formation by staphylothrombin facilitates Staphylococcus aureus-induced platelet aggregation. Thromb Haemost 2012 0.92
43 The role of staphylothrombin-mediated fibrin deposition in catheter-related Staphylococcus aureus infections. J Infect Dis 2013 0.92
44 P2X1-mediated ERK2 activation amplifies the collagen-induced platelet secretion by enhancing myosin light chain kinase activation. J Biol Chem 2003 0.92
45 Thrombotic risk assessment in the antiphospholipid syndrome requires more than the quantification of lupus anticoagulants. Blood 2009 0.91
46 Monoclonal antibody IAC-1 is specific for activated alpha2beta1 and binds to amino acids 199 to 201 of the integrin alpha2 I-domain. Blood 2004 0.91
47 PACAP and its receptor VPAC1 regulate megakaryocyte maturation: therapeutic implications. Blood 2007 0.90
48 Pathophysiological role of vascular smooth muscle alkaline phosphatase in medial artery calcification. J Bone Miner Res 2015 0.90
49 Molecular cloning and characterization of the GATA1 cofactor human FOG1 and assessment of its binding to GATA1 proteins carrying D218 substitutions. Hum Genet 2002 0.90
50 PEAR1 attenuates megakaryopoiesis via control of the PI3K/PTEN pathway. Blood 2013 0.90
51 Pseudohypoparathyroidism type Ib with disturbed imprinting in the GNAS1 cluster and Gsalpha deficiency in platelets. Hum Mol Genet 2002 0.89
52 Gallic acid antagonizes P-selectin-mediated platelet-leukocyte interactions: implications for the French paradox. Circulation 2005 0.88
53 ATP augments von Willebrand factor-dependent shear-induced platelet aggregation through Ca2+-calmodulin and myosin light chain kinase activation. J Biol Chem 2004 0.87
54 Hemostasis and inflammation: two of a kind? Thromb J 2009 0.87
55 Challenges in the diagnosis of the antiphospholipid syndrome. Clin Chem 2010 0.87
56 Specific inhibition of P-selectin-mediated cell adhesion by phage display-derived peptide antagonists. Blood 2002 0.86
57 Laboratory diagnosis of the antiphospholipid syndrome: a plethora of obstacles to overcome. Eur J Haematol 2009 0.86
58 Air pollution-associated procoagulant changes: the role of circulating microvesicles. J Thromb Haemost 2012 0.86
59 Traffic air pollution and oxidized LDL. PLoS One 2011 0.85
60 P2X(1)-mediated activation of extracellular signal-regulated kinase 2 contributes to platelet secretion and aggregation induced by collagen. Blood 2002 0.85
61 Short-term effect of infliximab is reflected in the clot lysis profile of patients with inflammatory bowel disease: a prospective study. Inflamm Bowel Dis 2015 0.84
62 Ablation of osteopontin improves the skeletal phenotype of phospho1(-/-) mice. J Bone Miner Res 2014 0.84
63 Platelet receptors. Handb Exp Pharmacol 2012 0.83
64 Rational optimization of a short human P-selectin-binding peptide leads to nanomolar affinity antagonists. J Biol Chem 2003 0.83
65 Effect of premature aging on murine adipose tissue. Exp Gerontol 2012 0.82
66 Effect of ageing on the murine venous circulation. Histochem Cell Biol 2012 0.81
67 Obesity promotes injury induced femoral artery thrombosis in mice. Thromb Res 2008 0.81
68 Age-associated adaptations in murine adipose tissues. Endocr J 2010 0.81
69 Increased Gs signalling in platelets and impaired collagen activation, due to a defect in the dystrophin gene, result in increased blood loss during spinal surgery. Hum Mol Genet 2007 0.81
70 Dabigatran inhibits Staphylococcus aureus coagulase activity. J Clin Microbiol 2010 0.80
71 Short-term ethinyl estradiol treatment suppresses inferior caval vein thrombosis in obese mice. Thromb Haemost 2009 0.80
72 Laboratory detection of the antiphospholipid syndrome via calibrated automated thrombography. Thromb Haemost 2009 0.80
73 The intracellular tyrosine residues of the ATP-gated P2X(1) ion channel are essential for its function. FEBS Lett 2002 0.80
74 The P2X1 ion channel in platelet function. Platelets 2010 0.79
75 Does rosiglitazone affect adiposity and cardiac function in genetic diabetic mice? Eur J Pharmacol 2012 0.79
76 Hemostatic effects of recombinant DisBa-01, a disintegrin from Bothrops alternatus. Front Biosci 2008 0.79
77 Thrombogenic changes in young and old mice upon subchronic exposure to air pollution in an urban roadside tunnel. Thromb Haemost 2012 0.79
78 Thrombin generation in plasma of healthy adults and children: chromogenic versus fluorogenic thrombogram analysis. Thromb Haemost 2007 0.78
79 Inhibition of von Willebrand factor-GPIb/IX/V interactions as a strategy to prevent arterial thrombosis. Expert Rev Cardiovasc Ther 2003 0.78
80 Facilitating roles of murine platelet glycoprotein Ib and alphaIIbbeta3 in phosphatidylserine exposure during vWF-collagen-induced thrombus formation. J Physiol 2004 0.78
81 Dietary enrichment of apolipoprotein E-deficient mice with extra virgin olive oil in combination with seal oil inhibits atherogenesis. Lipids Health Dis 2011 0.78
82 Thrombospondin-1 in von Willebrand factor function. Curr Drug Targets 2008 0.78
83 Plasma glycocalicin as a source of GPIbalpha in the von Willebrand factor ristocetin cofactor ELISA. Thromb Haemost 2005 0.77
84 Factor V Leiden mutation is associated with enhanced arterial thrombotic tendency in lean but not in obese mice. Thromb Haemost 2007 0.77
85 Diagnostic test combinations associated with thrombosis in lupus anticoagulant positive patients. Thromb Haemost 2011 0.77
86 Effect of VPAC1 Blockade on Adipose Tissue Formation and Composition in Mouse Models of Nutritionally Induced Obesity. J Obes 2010 0.77
87 Mechanical stress activates platelets at a subhemolysis level: an in vitro study. Artif Organs 2007 0.77
88 Is there an association between complement activation and antiphospholipid antibody-related thrombosis? Thromb Haemost 2010 0.77
89 Evaluation of the profibrinolytic properties of an anti-TAFI monoclonal antibody in a mouse thromboembolism model. Blood 2011 0.76
90 Thrombopoietic effect of VPAC1 inhibition during megakaryopoiesis. Br J Haematol 2010 0.76
91 Prothrombotic effect of Rofecoxib in a murine venous thrombosis model. Thromb Res 2008 0.76
92 Relationship between inflammation and venous thromboembolism as studied by microparticle assessment in plasma. J Am Coll Cardiol 2005 0.76
93 Effects of pH on the production of phosphate and pyrophosphate by matrix vesicles' biomimetics. Calcif Tissue Int 2013 0.76
94 Does the P(2X1del) variant lacking 17 amino acids in its extracellular domain represent a relevant functional ion channel in platelets? Blood 2002 0.75
95 Shielding the front-strand beta 3 of the von Willebrand factor A1 domain inhibits its binding to platelet glycoprotein Ibalpha. Blood 2002 0.75
96 Thrombophilia in mice expressing a tissue factor variant lacking its transmembrane and cytosolic domain. Biochem Biophys Res Commun 2005 0.75
97 Fibrin- and collagen-based matrices attenuate inflammatory and procoagulant responses in human endothelial cell cultures exposed to Staphylococcus aureus. Tissue Eng Part A 2011 0.75
98 Thrombin Generation by Fetoscopic Trauma to the Fetal Membranes: An in vivo and in vitro Study. Fetal Diagn Ther 2015 0.75
99 ADAMTS13 deficiency promotes microthrombosis in a murine model of diet-induced liver steatosis. Thromb Haemost 2016 0.75
100 Structure, genomic DNA typing, and kinetic characterization of the D allozyme of placental alkaline phosphatase (PLAP/ALPP). Hum Mutat 2002 0.75
101 Three-dimensional reconstruction of thrombus formation during photochemically induced arterial and venous thrombosis. Ann Biomed Eng 2003 0.75
102 Age-associated pro-inflammatory adaptations of the mouse thoracic aorta. Thromb Haemost 2013 0.75