Olivier Hyrien

Author PubWeight™ 25.54‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Impact of replication timing on non-CpG and CpG substitution rates in mammalian genomes. Genome Res 2010 2.37
2 Control of replication origin density and firing time in Xenopus egg extracts: role of a caffeine-sensitive, ATR-dependent checkpoint. J Biol Chem 2004 2.05
3 Replication of the chicken beta-globin locus: early-firing origins at the 5' HS4 insulator and the rho- and betaA-globin genes show opposite epigenetic modifications. Mol Cell Biol 2003 1.31
4 Broadening of DNA replication origin usage during metazoan cell differentiation. EMBO Rep 2006 1.26
5 A dynamic stochastic model for DNA replication initiation in early embryos. PLoS One 2008 1.24
6 Evidence for sequential and increasing activation of replication origins along replication timing gradients in the human genome. PLoS Comput Biol 2011 1.20
7 Cdc45 is a critical effector of myc-dependent DNA replication stress. Cell Rep 2013 1.16
8 Universal temporal profile of replication origin activation in eukaryotes. PLoS One 2009 1.14
9 Replication fork polarity gradients revealed by megabase-sized U-shaped replication timing domains in human cell lines. PLoS Comput Biol 2012 1.12
10 ATR/Chk1 pathway is essential for resumption of DNA synthesis and cell survival in UV-irradiated XP variant cells. Hum Mol Genet 2010 1.05
11 Topoisomerase II-DNA complexes trapped by ICRF-193 perturb chromatin structure. EMBO Rep 2005 1.02
12 Replication-associated mutational asymmetry in the human genome. Mol Biol Evol 2011 1.02
13 Proliferating human cells hypomorphic for origin recognition complex 2 and pre-replicative complex formation have a defect in p53 activation and Cdk2 kinase activation. J Biol Chem 2006 0.98
14 A simple and optimized method of producing silanized surfaces for FISH and replication mapping on combed DNA fibers. Biotechniques 2008 0.97
15 Y RNA functions at the initiation step of mammalian chromosomal DNA replication. J Cell Sci 2009 0.96
16 DNA replication timing is deterministic at the level of chromosomal domains but stochastic at the level of replicons in Xenopus egg extracts. Nucleic Acids Res 2008 0.96
17 Site-specific and temporally controlled initiation of DNA replication in a human cell-free system. Nucleic Acids Res 2002 0.91
18 Use of DNA combing to study DNA replication in Xenopus and human cell-free systems. Methods Mol Biol 2009 0.91
19 Multiscale analysis of genome-wide replication timing profiles using a wavelet-based signal-processing algorithm. Nat Protoc 2012 0.89
20 Replication-fork stalling and processing at a single psoralen interstrand crosslink in Xenopus egg extracts. PLoS One 2011 0.87
21 Do replication forks control late origin firing in Saccharomyces cerevisiae? Nucleic Acids Res 2011 0.82
22 Visualization of bidirectional initiation of chromosomal DNA replication in a human cell free system. Nucleic Acids Res 2005 0.81
23 DNA topoisomerase IIα controls replication origin cluster licensing and firing time in Xenopus egg extracts. Nucleic Acids Res 2013 0.80
24 Single-molecule, antibody-free fluorescent visualisation of replication tracts along barcoded DNA molecules. Int J Dev Biol 2016 0.75