PubRank

Marc Diederich

Author PubWeight™ 105.29‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Chemopreventive and therapeutic effects of curcumin. Cancer Lett 2004 2.40
2 Molecular and therapeutic potential and toxicity of valproic acid. J Biomed Biotechnol 2010 2.13
3 The role of cyclooxygenase-2 in cell proliferation and cell death in human malignancies. Int J Cell Biol 2010 1.51
4 Modulation of anti-apoptotic and survival pathways by curcumin as a strategy to induce apoptosis in cancer cells. Biochem Pharmacol 2008 1.41
5 Gold from the sea: marine compounds as inhibitors of the hallmarks of cancer. Biotechnol Adv 2011 1.25
6 Chemopreventive potential of curcumin in prostate cancer. Genes Nutr 2009 1.14
7 A beginner's guide to NF-kappaB signaling pathways. Ann N Y Acad Sci 2004 1.13
8 Melatonin: a pleiotropic molecule regulating inflammation. Biochem Pharmacol 2010 1.13
9 Multistep and multitask Bax activation. Mitochondrion 2010 1.11
10 A survey of marine natural compounds and their derivatives with anti-cancer activity reported in 2011. Molecules 2013 1.11
11 Epigenomics of leukemia: from mechanisms to therapeutic applications. Epigenomics 2011 1.11
12 Sustained exposure to the DNA demethylating agent, 2'-deoxy-5-azacytidine, leads to apoptotic cell death in chronic myeloid leukemia by promoting differentiation, senescence, and autophagy. Biochem Pharmacol 2010 1.05
13 Traditional West African pharmacopeia, plants and derived compounds for cancer therapy. Biochem Pharmacol 2012 1.03
14 A LIM domain protein from tobacco involved in actin-bundling and histone gene transcription. Mol Plant 2012 1.03
15 Heteronemin, a spongean sesterterpene, inhibits TNF alpha-induced NF-kappa B activation through proteasome inhibition and induces apoptotic cell death. Biochem Pharmacol 2010 1.02
16 Modulation of poly(ADP-ribosylation) in apoptotic cells. Biochem Pharmacol 2004 1.01
17 DNA demethylation increases sensitivity of neuroblastoma cells to chemotherapeutic drugs. Biochem Pharmacol 2012 1.00
18 Dietary chalcones with chemopreventive and chemotherapeutic potential. Genes Nutr 2011 1.00
19 Inhibition of TNFalpha-induced activation of nuclear factor kappaB by kava (Piper methysticum) derivatives. Biochem Pharmacol 2006 0.99
20 DNA damage response: the emerging role of c-Abl as a regulatory switch? Biochem Pharmacol 2011 0.99
21 Marine natural products as targeted modulators of the transcription factor NF-kappaB. Biochem Pharmacol 2007 0.98
22 Epigenetics Offer New Horizons for Colorectal Cancer Prevention. Curr Colorectal Cancer Rep 2012 0.97
23 Reply to: Cisplatin-induced primordial follicle oocyte killing and loss of fertility are not prevented by imatinib. Nat Med 2012 0.97
24 Curcumin as a regulator of epigenetic events. Mol Nutr Food Res 2013 0.97
25 Potential of the dietary antioxidants resveratrol and curcumin in prevention and treatment of hematologic malignancies. Molecules 2010 0.96
26 GATA-1: friends, brothers, and coworkers. Ann N Y Acad Sci 2004 0.96
27 Dermacozines, a new phenazine family from deep-sea dermacocci isolated from a Mariana Trench sediment. Org Biomol Chem 2010 0.95
28 Anti-proliferative potential of curcumin in androgen-dependent prostate cancer cells occurs through modulation of the Wingless signaling pathway. Int J Oncol 2011 0.95
29 Antioxidant and anti-proliferative properties of lycopene. Free Radic Res 2011 0.95
30 Targeting COX-2 expression by natural compounds: a promising alternative strategy to synthetic COX-2 inhibitors for cancer chemoprevention and therapy. Biochem Pharmacol 2010 0.95
31 Synthesis and cytotoxic potential of heterocyclic cyclohexanone analogues of curcumin. Bioorg Med Chem 2010 0.95
32 Assembling the puzzle of anti-cancer mechanisms triggered by cardiac glycosides. Mitochondrion 2012 0.95
33 Tumor necrosis factor alpha inhibits erythroid differentiation in human erythropoietin-dependent cells involving p38 MAPK pathway, GATA-1 and FOG-1 downregulation and GATA-2 upregulation. Biochem Pharmacol 2008 0.95
34 UNBS1450, a steroid cardiac glycoside inducing apoptotic cell death in human leukemia cells. Biochem Pharmacol 2010 0.93
35 Curcumin-the paradigm of a multi-target natural compound with applications in cancer prevention and treatment. Toxins (Basel) 2010 0.93
36 Natural compounds as regulators of the cancer cell metabolism. Int J Cell Biol 2013 0.91
37 The inhibition of TNF-alpha-induced NF-kappaB activation by marine natural products. Biochem Pharmacol 2009 0.90
38 Chemical properties and mechanisms determining the anti-cancer action of garlic-derived organic sulfur compounds. Anticancer Agents Med Chem 2011 0.90
39 Embellicines A and B: absolute configuration and NF-κB transcriptional inhibitory activity. J Med Chem 2013 0.89
40 Dietary compounds as potent inhibitors of the signal transducers and activators of transcription (STAT) 3 regulatory network. Genes Nutr 2012 0.89
41 Anticancer effect of altersolanol A, a metabolite produced by the endophytic fungus Stemphylium globuliferum, mediated by its pro-apoptotic and anti-invasive potential via the inhibition of NF-κB activity. Bioorg Med Chem 2013 0.88
42 Sp proteins play a critical role in histone deacetylase inhibitor-mediated derepression of CYP46A1 gene transcription. J Neurochem 2010 0.88
43 An introduction to the molecular mechanisms of apoptosis. Ann N Y Acad Sci 2003 0.88
44 Linking anemia to inflammation and cancer: the crucial role of TNFalpha. Biochem Pharmacol 2009 0.88
45 Curcumin regulates signal transducer and activator of transcription (STAT) expression in K562 cells. Biochem Pharmacol 2006 0.88
46 Anti-inflammatory, pro-apoptotic, and anti-proliferative effects of a methanolic neem (Azadirachta indica) leaf extract are mediated via modulation of the nuclear factor-κB pathway. Genes Nutr 2010 0.87
47 Effect of curcumin on nuclear factor kappaB signaling pathways in human chronic myelogenous K562 leukemia cells. Ann N Y Acad Sci 2009 0.87
48 Chromatin-modifying agents in anti-cancer therapy. Biochimie 2012 0.86
49 Venus Flytrap (Dionaea muscipula Solander ex Ellis) Contains Powerful Compounds that Prevent and Cure Cancer. Front Oncol 2013 0.86
50 ROS-independent JNK activation and multisite phosphorylation of Bcl-2 link diallyl tetrasulfide-induced mitotic arrest to apoptosis. Carcinogenesis 2012 0.86
51 Melatonin antagonizes the intrinsic pathway of apoptosis via mitochondrial targeting of Bcl-2. J Pineal Res 2008 0.86
52 Parkinson's disease: a complex interplay of mitochondrial DNA alterations and oxidative stress. Int J Mol Sci 2013 0.86
53 NF-kappaB-inhibiting naphthopyrones from the Fijian echinoderm Comanthus parvicirrus. J Nat Prod 2007 0.85
54 Induction of apoptosis by curcumin: mediation by glutathione S-transferase P1-1 inhibition. Biochem Pharmacol 2003 0.85
55 Anticancer bioactivity of compounds from medicinal plants used in European medieval traditions. Biochem Pharmacol 2013 0.85
56 Oxidative, multistep activation of the noncanonical NF-kappaB pathway via disulfide Bcl-3/p50 complex. FASEB J 2008 0.85
57 Histone deacetylase 6 in health and disease. Epigenomics 2015 0.85
58 Selective modulation of the glucocorticoid receptor can distinguish between transrepression of NF-κB and AP-1. Cell Mol Life Sci 2013 0.84
59 Cox-2 inhibitors induce early c-Myc downregulation and lead to expression of differentiation markers in leukemia cells. Cell Cycle 2011 0.84
60 Diallylpolysulfides induce growth arrest and apoptosis. Int J Oncol 2010 0.84
61 MicroRNAs in cancer management and their modulation by dietary agents. Biochem Pharmacol 2012 0.84
62 Tumor necrosis factor alpha induces gamma-glutamyltransferase expression via nuclear factor-kappaB in cooperation with Sp1. Biochem Pharmacol 2008 0.84
63 Anti-inflammatory and anticancer drugs from nature. Cancer Treat Res 2014 0.84
64 Valproic acid perturbs hematopoietic homeostasis by inhibition of erythroid differentiation and activation of the myelo-monocytic pathway. Biochem Pharmacol 2010 0.84
65 Selective antimicrobial activity associated with sulfur nanoparticles. J Biomed Nanotechnol 2011 0.84
66 A novel coumarin-quinone derivative SV37 inhibits CDC25 phosphatases, impairs proliferation, and induces cell death. Mol Carcinog 2013 0.84
67 COX-2 inhibitors block chemotherapeutic agent-induced apoptosis prior to commitment in hematopoietic cancer cells. Biochem Pharmacol 2011 0.83
68 Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells. J Med Chem 2014 0.83
69 Tumor necrosis factor α-mediated inhibition of erythropoiesis involves GATA-1/GATA-2 balance impairment and PU.1 over-expression. Biochem Pharmacol 2011 0.83
70 Tanzawaic acids isolated from a marine-derived fungus of the genus Penicillium with cytotoxic activities. Org Biomol Chem 2015 0.83
71 Histone deacetylase modulators provided by Mother Nature. Genes Nutr 2012 0.83
72 Regulation of glutathione S-transferase P1-1 gene expression by NF-kappaB in tumor necrosis factor alpha-treated K562 leukemia cells. Biochem Pharmacol 2004 0.83
73 Long and short non-coding RNAs as regulators of hematopoietic differentiation. Int J Mol Sci 2013 0.83
74 NF kappa B inhibitors and antitrypanosomal metabolites from endophytic fungus Penicillium sp. isolated from Limonium tubiflorum. Bioorg Med Chem 2010 0.82
75 A survey of marine natural compounds and their derivatives with anti-cancer activity reported in 2010. Molecules 2011 0.82
76 Marine natural products targeting phospholipases A2. Biochem Pharmacol 2010 0.82
77 The inhibitory effect of the proinflammatory cytokine TNFalpha on erythroid differentiation involves erythroid transcription factor modulation. Int J Oncol 2009 0.82
78 Synthesis and selective anticancer activity of organochalcogen based redox catalysts. J Med Chem 2010 0.82
79 Protein kinase and HDAC inhibitors from the endophytic fungus Epicoccum nigrum. J Nat Prod 2013 0.82
80 Targeting the wingless signaling pathway with natural compounds as chemopreventive or chemotherapeutic agents. Curr Pharm Biotechnol 2012 0.81
81 Oxidative upregulation of Bcl-2 in healthy lymphocytes. Ann N Y Acad Sci 2006 0.81
82 PPARγ-inactive Δ2-troglitazone independently triggers ER stress and apoptosis in breast cancer cells. Mol Carcinog 2013 0.81
83 Pro-apoptotic and immunostimulatory tetrahydroxanthone dimers from the endophytic fungus Phomopsis longicolla. J Org Chem 2013 0.81
84 The dual role of calcium as messenger and stressor in cell damage, death, and survival. Int J Cell Biol 2010 0.81
85 UNBS1450 from Calotropis procera as a regulator of signaling pathways involved in proliferation and cell death. Biochem Pharmacol 2009 0.81
86 Cell cycle arrest in early mitosis and induction of caspase-dependent apoptosis in U937 cells by diallyltetrasulfide (Al2S4). Apoptosis 2009 0.81
87 Radicicol-mediated inhibition of Bcr-Abl in K562 cells induced p38-MAPK dependent erythroid differentiation and PU.1 down-regulation. Biofactors 2008 0.80
88 Effect of chemopreventive agents on glutathione S-transferase P1-1 gene expression mechanisms via activating protein 1 and nuclear factor kappaB inhibition. Biochem Pharmacol 2004 0.80
89 Gene expression profiling related to anti-inflammatory properties of curcumin in K562 leukemia cells. Ann N Y Acad Sci 2009 0.80
90 Oxidative Stress, DNA Damage, and c-Abl Signaling: At the Crossroad in Neurodegenerative Diseases? Int J Cell Biol 2012 0.80
91 Induction of heat shock response by curcumin in human leukemia cells. Cancer Lett 2009 0.80
92 Natural compounds as inflammation inhibitors. Genes Nutr 2011 0.80
93 The aromatic ketone 4'-hydroxychalcone inhibits TNFα-induced NF-κB activation via proteasome inhibition. Biochem Pharmacol 2011 0.80
94 Reversible epigenetic fingerprint-mediated glutathione-S-transferase P1 gene silencing in human leukemia cell lines. Biochem Pharmacol 2011 0.80
95 Role of Histone Acetylation in Cell Cycle Regulation. Curr Top Med Chem 2016 0.79
96 Tumor necrosis factor alpha inhibits aclacinomycin A-induced erythroid differentiation of K562 cells via GATA-1. Cancer Lett 2005 0.79
97 Styryl-lactone goniothalamin inhibits TNF-α-induced NF-κB activation. Food Chem Toxicol 2013 0.79
98 Curcumin stability and its effect on glutathione S-transferase P1-1 mRNA expression in K562 cells. Ann N Y Acad Sci 2004 0.79
99 Antiproliferative effect of natural tetrasulfides in human breast cancer cells is mediated through the inhibition of the cell division cycle 25 phosphatases. Int J Oncol 2011 0.78
100 Expression of glutathione S-transferase P1-1 in leukemic cells is regulated by inducible AP-1 binding. Cancer Lett 2004 0.78
101 Increased glutathione S-transferase P1-1 expression by mRNA stabilization in hemin-induced differentiation of K562 cells. Biochem Pharmacol 2004 0.78
102 Intracellular prooxidant activity of melatonin induces a survival pathway involving NF-kappaB activation. Ann N Y Acad Sci 2009 0.78
103 Bioactive diterpene derivatives from the marine sponge Spongionella sp. J Nat Prod 2009 0.78
104 Redox regulation: natural compound as regulators of inflammation signaling. Biochem Pharmacol 2012 0.78
105 Identification of differentially expressed proteins in curcumin-treated prostate cancer cell lines. OMICS 2012 0.77
106 Phorbol ester regulation of the human gamma-glutamyltransferase gene promoter. Biochem Biophys Res Commun 2004 0.77
107 Transcriptional and post-transcriptional regulation of glutathione S-transferase P1 expression during butyric acid-induced differentiation of K562 cells. Leuk Res 2005 0.77
108 Expression of glutathione S-transferase P1-1 in differentiating K562: role of GATA-1. Biochem Biophys Res Commun 2003 0.77
109 The DNA hypomethylating agent, 5-aza-2'-deoxycytidine, enhances tumor cell invasion through a transcription-dependent modulation of MMP-1 expression in human fibrosarcoma cells. Mol Carcinog 2013 0.77
110 Sequential phases of Ca2+ alterations in pre-apoptotic cells. Apoptosis 2007 0.76
111 Metabolism and cancer: old and new players. Int J Cell Biol 2013 0.76
112 In vitro characterisation of the anti-intravasative properties of the marine product heteronemin. Arch Toxicol 2013 0.76
113 Subapoptogenic oxidative stress strongly increases the activity of the glycolytic key enzyme glyceraldehyde 3-phosphate dehydrogenase. Ann N Y Acad Sci 2009 0.76
114 Magnetic fields promote a pro-survival non-capacitative Ca2+ entry via phospholipase C signaling. Int J Biochem Cell Biol 2010 0.76
115 Aurones: interesting natural and synthetic compounds with emerging biological potential. Nat Prod Commun 2012 0.76
116 Effect of curcumin treatment on protein phosphorylation in K562 cells. Ann N Y Acad Sci 2007 0.75
117 Polyphenol tri-vanillic ester 13c inhibits P-JAK2V617F and Bcr-Abl oncokinase expression in correlation with STAT3/STAT5 inactivation and apoptosis induction in human leukemia cells. Cancer Lett 2013 0.75
118 Integrated cellular pathology-systems biology of human diseases. OMICS 2012 0.75
119 Integrated cellular pathology--systems biology of human diseases. Biochem Pharmacol 2011 0.75
120 Targeting inflammatory cell signaling mechanisms: a promising road to new therapeutic agents in chemoprevention and cancer therapy. J Exp Ther Oncol 2011 0.75
121 Decrypting the labyrinth of inflammatory cell signaling pathways: Editorial to the meeting "Inflammation 2010". J Cell Commun Signal 2010 0.75
122 Discovery and Characterization of R/S-N-3-Cyanophenyl-N'-(6-tert-butoxycarbonylamino-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-4-yl)urea, a New Histone Deacetylase Class III Inhibitor Exerting Antiproliferative Activity Against Cancer Cell Lines. J Med Chem 2017 0.75
123 Inflammation: novel arrows for an ancient target. Biochem Pharmacol 2010 0.75
124 Conference Scene: Omic technologies in human disease: extending the network of epigenetic control. Epigenomics 2011 0.75