PubRank

Bernard Ducommun

Author PubWeight™ 70.62‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 CDC25 phosphatases in cancer cells: key players? Good targets? Nat Rev Cancer 2007 3.46
2 The human dynamin-related protein OPA1 is anchored to the mitochondrial inner membrane facing the inter-membrane space. FEBS Lett 2002 2.30
3 The when and wheres of CDC25 phosphatases. Curr Opin Cell Biol 2006 2.28
4 Phosphorylation of CDC25B by Aurora-A at the centrosome contributes to the G2-M transition. J Cell Sci 2004 1.93
5 Pharmacological inhibition of aurora-A but not aurora-B impairs interphase microtubule dynamics. Cell Cycle 2009 1.48
6 The cell cycle regulator CDC25A is a target for JAK2V617F oncogene. Blood 2011 1.47
7 3D imaging of the response to CDC25 inhibition in multicellular spheroids. Cancer Biol Ther 2009 1.45
8 Microcephalin and pericentrin regulate mitotic entry via centrosome-associated Chk1. J Cell Biol 2009 1.41
9 Multicellular tumor spheroid model to evaluate spatio-temporal dynamics effect of chemotherapeutics: application to the gemcitabine/CHK1 inhibitor combination in pancreatic cancer. BMC Cancer 2012 1.28
10 Cell cycle control by the CDC25 phosphatases. Anticancer Agents Med Chem 2008 1.22
11 OPA1 functions in mitochondria and dysfunctions in optic nerve. Int J Biochem Cell Biol 2009 1.19
12 CDC25B phosphorylation by Aurora-A occurs at the G2/M transition and is inhibited by DNA damage. Cell Cycle 2005 1.18
13 CHK1 phosphorylates CDC25B during the cell cycle in the absence of DNA damage. J Cell Sci 2006 1.16
14 Live cell division dynamics monitoring in 3D large spheroid tumor models using light sheet microscopy. Cell Div 2011 1.12
15 Human pEg3 kinase associates with and phosphorylates CDC25B phosphatase: a potential role for pEg3 in cell cycle regulation. Oncogene 2002 1.11
16 CDC25B involvement in the centrosome duplication cycle and in microtubule nucleation. Cancer Res 2007 1.06
17 Constitutive activation of the DNA damage signaling pathway in acute myeloid leukemia with complex karyotype: potential importance for checkpoint targeting therapy. Cancer Res 2009 1.03
18 Design, synthesis, and biological evaluation of novel naphthoquinone derivatives with CDC25 phosphatase inhibitory activity. Bioorg Med Chem 2005 1.03
19 Interaction of p21(CDKN1A) with PCNA regulates the histone acetyltransferase activity of p300 in nucleotide excision repair. Nucleic Acids Res 2008 1.01
20 Protein kinase CK2 regulates CDC25B phosphatase activity. Oncogene 2003 1.00
21 Genotoxic-activated G2-M checkpoint exit is dependent on CDC25B phosphatase expression. Mol Cancer Ther 2006 0.99
22 The polo-like kinase 1 regulates CDC25B-dependent mitosis entry. Biochim Biophys Acta 2009 0.98
23 Multicellular tumor spheroid models to explore cell cycle checkpoints in 3D. BMC Cancer 2013 0.95
24 Receptor-based virtual ligand screening for the identification of novel CDC25 phosphatase inhibitors. J Chem Inf Model 2007 0.94
25 What's new on CDC25 phosphatase inhibitors. Pharmacol Ther 2007 0.94
26 CDC25B phosphorylated by pEg3 localizes to the centrosome and the spindle poles at mitosis. Cell Cycle 2005 0.94
27 p21CDKN1A does not interfere with loading of PCNA at DNA replication sites, but inhibits subsequent binding of DNA polymerase delta at the G1/S phase transition. Cell Cycle 2003 0.93
28 Characterization of the antiproliferative activity of Xylopia aethiopica. Cell Div 2012 0.92
29 Moderate variations in CDC25B protein levels modulate the response to DNA damaging agents. Cell Cycle 2008 0.92
30 Deep and clear optical imaging of thick inhomogeneous samples. PLoS One 2012 0.91
31 CDC25B phosphorylation by p38 and MK-2. Cell Cycle 2006 0.91
32 Distinct pools of proliferating cell nuclear antigen associated to DNA replication sites interact with the p125 subunit of DNA polymerase delta or DNA ligase I. Exp Cell Res 2004 0.90
33 Identification of an unexpected link between the Shh pathway and a G2/M regulator, the phosphatase CDC25B. Dev Biol 2006 0.90
34 Inhibition of human tumor cell growth in vivo by an orally bioavailable inhibitor of CDC25 phosphatases. Mol Cancer Ther 2005 0.89
35 Linking PCNA-dependent replication and ATR by human Claspin. Biochem Biophys Res Commun 2007 0.88
36 IRC-083864, a novel bis quinone inhibitor of CDC25 phosphatases active against human cancer cells. Int J Cancer 2009 0.88
37 Mechanical stress impairs mitosis progression in multi-cellular tumor spheroids. PLoS One 2013 0.88
38 Inhibitors of the CDC25 phosphatases. Prog Cell Cycle Res 2003 0.87
39 Unscheduled expression of CDC25B in S-phase leads to replicative stress and DNA damage. Mol Cancer 2010 0.87
40 A screen for deubiquitinating enzymes involved in the G₂/M checkpoint identifies USP50 as a regulator of HSP90-dependent Wee1 stability. Cell Cycle 2010 0.87
41 The CDC25B phosphatase shortens the G2 phase of neural progenitors and promotes efficient neuron production. Development 2012 0.86
42 Nuclear localization of CDC25B1 and serine 146 integrity are required for induction of mitosis. J Biol Chem 2002 0.85
43 Synthesis and biological evaluation of novel heterocyclic quinones as inhibitors of the dual specificity protein phosphatase CDC25C. Bioorg Med Chem Lett 2005 0.84
44 Asymmetric localization of the CDC25B phosphatase to the mother centrosome during interphase. Cell Cycle 2007 0.84
45 Evaluation of checkpoint kinase targeting therapy in acute myeloid leukemia with complex karyotype. Cancer Biol Ther 2012 0.83
46 Evaluation of Polo-like Kinase 1 inhibition on the G2/M checkpoint in Acute Myelocytic Leukaemia. Eur J Pharmacol 2008 0.83
47 CDC25B overexpression stabilises centrin 2 and promotes the formation of excess centriolar foci. PLoS One 2013 0.83
48 Mitotic phosphorylation of Cdc25B Ser321 disrupts 14-3-3 binding to the high affinity Ser323 site. J Biol Chem 2010 0.83
49 A novel synthetic inhibitor of CDC25 phosphatases: BN82002. Cancer Res 2004 0.83
50 Pharmacologic inhibition of CDC25 phosphatases impairs interphase microtubule dynamics and mitotic spindle assembly. Mol Cancer Ther 2007 0.82
51 NanoLC-MS/MS analysis provides new insights into the phosphorylation pattern of Cdc25B in vivo: full overlap with sites of phosphorylation by Chk1 and Cdk1/cycB kinases in vitro. J Proteome Res 2008 0.82
52 A versatile sample holder for single plane illumination microscopy. J Microsc 2013 0.80
53 PKB/Akt phosphorylates the CDC25B phosphatase and regulates its intracellular localisation. Biol Cell 2003 0.80
54 Phosphorylation of CDC25C at S263 controls its intracellular localisation. FEBS Lett 2007 0.80
55 Identification of N-terminally truncated stable nuclear isoforms of CDC25B that are specifically involved in G2/M checkpoint recovery. Cancer Res 2011 0.79
56 UV-induced downregulation of the CDC25B protein in human cells. FEBS Lett 2010 0.79
57 Human CDC25B and CDC25C differ by their ability to restore a functional checkpoint response after gene replacement in fission yeast. Biochem Biophys Res Commun 2002 0.78
58 Cell adhesion regulates CDC25A expression and proliferation in acute myeloid leukemia. Cancer Res 2006 0.78
59 A new mitotic-cell specific monoclonal antibody. Cell Cycle 2007 0.78
60 Evolutionary conservation of a novel splice variant of the Cds1/CHK2 checkpoint kinase restricted to its regulatory domain. Cell Cycle 2004 0.78
61 CDC25B associates with a centrin 2-containing complex and is involved in maintaining centrosome integrity. Biol Cell 2011 0.78
62 Study of the docking-dependent PLK1 phosphorylation of the CDC25B phosphatase. Biochem Biophys Res Commun 2011 0.78
63 [Bacterial cyclostatin, or how do bacteria manipulate the eukaryotic cell cycle]. Med Sci (Paris) 2003 0.78
64 LIM-only protein FHL3 interacts with CDC25B2 phosphatase. Exp Cell Res 2003 0.78
65 Novel naphthoquinone and quinolinedione inhibitors of CDC25 phosphatase activity with antiproliferative properties. Bioorg Med Chem 2008 0.77
66 What similarity between human and fission yeast proteins is required for orthology? Yeast 2002 0.77
67 Microdevice arrays of high aspect ratio poly(dimethylsiloxane) pillars for the investigation of multicellular tumour spheroid mechanical properties. Lab Chip 2014 0.76
68 Synthesis of small molecule CDC25 phosphatases inhibitors. Bioorg Med Chem Lett 2004 0.76
69 Structure Tensor Based Analysis of Cells and Nuclei Organization in Tissues. IEEE Trans Med Imaging 2015 0.76
70 Ability of human CDC25B phosphatase splice variants to replace the function of the fission yeast Cdc25 cell cycle regulator. FEMS Yeast Res 2004 0.76
71 The "starter" and "gas pedal" of mitosis reside at the centrosome. Commentary on "characterization of centrosomal localization and dynamics of CDC25C phosphatase in mitosis" by Bonnet et al. Cell Cycle 2008 0.75
72 Chromatibody, a novel non-invasive molecular tool to explore and manipulate chromatin in living cells. Development 2016 0.75
73 5-Substituted [1]pyrindine derivatives with antiproliferative activity. Eur J Med Chem 2009 0.75
74 Development of novel thiazolopyrimidines as CDC25B phosphatase inhibitors. ChemMedChem 2009 0.75
75 A fission yeast strain expressing human CDC25A phosphatase: a tool for selectivity studies of pharmacological inhibitors of CDC25. Curr Genet 2004 0.75
76 Synthesis and biological evaluation of analogs of the marine alkaloids granulatimide and isogranulatimide. Eur J Med Chem 2012 0.75