Tony Mok

Author PubWeight™ 124.73‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling. Science 2007 32.68
2 Crizotinib versus chemotherapy in advanced ALK-positive lung cancer. N Engl J Med 2013 14.78
3 Phase III study of afatinib or cisplatin plus pemetrexed in patients with metastatic lung adenocarcinoma with EGFR mutations. J Clin Oncol 2013 11.68
4 First-line crizotinib versus chemotherapy in ALK-positive lung cancer. N Engl J Med 2014 10.91
5 Gefitinib versus docetaxel in previously treated non-small-cell lung cancer (INTEREST): a randomised phase III trial. Lancet 2008 10.74
6 Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC. Cancer Cell 2010 7.78
7 Molecular predictors of outcome with gefitinib and docetaxel in previously treated non-small-cell lung cancer: data from the randomized phase III INTEREST trial. J Clin Oncol 2009 4.27
8 Intercalated combination of chemotherapy and erlotinib for patients with advanced stage non-small-cell lung cancer (FASTACT-2): a randomised, double-blind trial. Lancet Oncol 2013 4.20
9 Management of non-small-cell lung cancer: recent developments. Lancet 2013 3.51
10 Activating mutations in the tyrosine kinase domain of the epidermal growth factor receptor are associated with improved survival in gefitinib-treated chemorefractory lung adenocarcinomas. Clin Cancer Res 2005 2.81
11 Epidermal growth factor receptor mutations and their correlation with gefitinib therapy in patients with non-small cell lung cancer: a meta-analysis based on updated individual patient data from six medical centers in mainland China. J Thorac Oncol 2007 2.15
12 Epidermal growth factor receptor mutation status in circulating free DNA in serum: from IPASS, a phase III study of gefitinib or carboplatin/paclitaxel in non-small cell lung cancer. J Thorac Oncol 2012 1.86
13 Clinical outcomes in non-small-cell lung cancer patients with EGFR mutations: pooled analysis. J Cell Mol Med 2009 1.62
14 Treatment Rationale Study Design for the MetLung Trial: A Randomized, Double-Blind Phase III Study of Onartuzumab (MetMAb) in Combination With Erlotinib Versus Erlotinib Alone in Patients Who Have Received Standard Chemotherapy for Stage IIIB or IV Met-Positive Non-Small-Cell Lung Cancer. Clin Lung Cancer 2012 1.16
15 Cost-effectiveness of epidermal growth factor receptor mutation testing and first-line treatment with gefitinib for patients with advanced adenocarcinoma of the lung. Cancer 2011 1.10
16 A multicenter phase II trial of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP, Triapine) and gemcitabine in advanced non-small-cell lung cancer with pharmacokinetic evaluation using peripheral blood mononuclear cells. Invest New Drugs 2007 1.04
17 Pooled analysis of clinical outcome for EGFR TKI-treated patients with EGFR mutation-positive NSCLC. J Cell Mol Med 2014 1.00
18 A phase II study of patients with metastatic or locoregionally recurrent nasopharyngeal carcinoma and evaluation of plasma Epstein-Barr virus DNA as a biomarker of efficacy. Cancer Chemother Pharmacol 2007 1.00
19 Liver resection after irinotecan, 5-fluorouracil, and folinic acid for patients with unresectable colorectal liver metastases: a multicenter phase II study by the Cancer Therapeutic Research Group. Med Oncol 2005 0.96
20 CRIPTO1 expression in EGFR-mutant NSCLC elicits intrinsic EGFR-inhibitor resistance. J Clin Invest 2014 0.95
21 PARP inhibition in BRCA-mutated breast and ovarian cancers. Lancet 2010 0.94
22 INSPIRE: A phase III study of the BLP25 liposome vaccine (L-BLP25) in Asian patients with unresectable stage III non-small cell lung cancer. BMC Cancer 2011 0.92
23 EGFR mutation testing practices within the Asia Pacific region: results of a multicenter diagnostic survey. J Thorac Oncol 2015 0.88
24 Smoking history as a predictive factor of treatment response in advanced non-small-cell lung cancer: a systematic review. Clin Lung Cancer 2011 0.88
25 Chemotherapy response in East Asian non-small cell lung cancer patients harboring wild-type or activating mutation of epidermal growth factor receptors. J Thorac Oncol 2010 0.88
26 Management of hepatocellular carcinoma: beyond sorafenib. Curr Oncol Rep 2012 0.87
27 First-line crizotinib in ALK-positive lung cancer. N Engl J Med 2015 0.86
28 Phase III, randomized, open-label, first-line study in Asia of gefitinib versus carboplatin/paclitaxel in clinically selected patients with advanced non-small-cell lung cancer: evaluation of patients recruited from mainland China. Asia Pac J Clin Oncol 2012 0.86
29 Epigenomic analysis of lung adenocarcinoma reveals novel DNA methylation patterns associated with smoking. Onco Targets Ther 2013 0.85
30 Tumor p16M is a possible marker of advanced stage in non-small cell lung cancer. J Surg Oncol 2002 0.84
31 Targeted agents in the third-/fourth-line treatment of patients with advanced (stage III/IV) non-small cell lung cancer (NSCLC). Cancer Treat Rev 2012 0.83
32 Unresectable hepatocellular carcinoma: randomized controlled trial of transarterial ethanol ablation versus transcatheter arterial chemoembolization. Radiology 2013 0.83
33 Third generation triplet cytotoxic chemotherapy in advanced non-small cell lung cancer: a systematic overview. Lung Cancer 2008 0.82
34 Reviewing the safety of erlotinib in non-small cell lung cancer. Expert Opin Drug Saf 2010 0.81
35 [Consensus on dignosis for ALK positive non-small cell lung cancer in China, the 2013 version]. Zhonghua Bing Li Xue Za Zhi 2013 0.80
36 Symptomatic reduction in free testosterone levels secondary to crizotinib use in male cancer patients. Cancer 2013 0.78
37 Systemic nonhormonal management of advanced prostate cancer and its likely impact on patients' survival and quality of life. Anticancer Drugs 2008 0.77
38 Phase II trial of gemcitabine-carboplatin-paclitaxel as neoadjuvant chemotherapy for operable non-small cell lung cancer. J Thorac Oncol 2006 0.77
39 Immediate Versus Delayed Treatment with EGFR Tyrosine Kinase Inhibitors after First-line Therapy in Advanced Non-small-cell Lung CANCER. Chin J Cancer Res 2011 0.75
40 Piloting electronic self report symptom assessment - Cancer (ESRA-C) in Hong Kong: a mixed method approach. Eur J Oncol Nurs 2010 0.75