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1
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Flow-cytometric isolation of human antibodies from a nonimmune Saccharomyces cerevisiae surface display library.
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Nat Biotechnol
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2003
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3.34
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2
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Preliminary evaluation of (177)Lu-labeled knottin peptides for integrin receptor-targeted radionuclide therapy.
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Eur J Nucl Med Mol Imaging
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2010
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1.75
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3
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Targeted contrast-enhanced ultrasound imaging of tumor angiogenesis with contrast microbubbles conjugated to integrin-binding knottin peptides.
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J Nucl Med
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2010
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1.50
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4
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Fine epitope mapping of anti-epidermal growth factor receptor antibodies through random mutagenesis and yeast surface display.
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J Mol Biol
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2004
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1.43
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5
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Design and fabrication of an artificial cornea based on a photolithographically patterned hydrogel construct.
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Biomed Microdevices
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2007
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1.38
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6
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Engineered knottin peptides: a new class of agents for imaging integrin expression in living subjects.
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Cancer Res
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2009
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1.38
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7
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Identification of the epitope for the epidermal growth factor receptor-specific monoclonal antibody 806 reveals that it preferentially recognizes an untethered form of the receptor.
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J Biol Chem
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2004
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1.23
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8
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Engineered cystine knot peptides that bind alphavbeta3, alphavbeta5, and alpha5beta1 integrins with low-nanomolar affinity.
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Proteins
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2009
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1.21
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9
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Engineered cystine-knot peptides that bind alpha(v)beta(3) integrin with antibody-like affinities.
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J Mol Biol
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2008
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1.12
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10
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Antibodies specifically targeting a locally misfolded region of tumor associated EGFR.
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Proc Natl Acad Sci U S A
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2009
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1.07
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11
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Soluble peptide-MHC monomers cause activation of CD8+ T cells through transfer of the peptide to T cell MHC molecules.
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Proc Natl Acad Sci U S A
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2002
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1.06
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12
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Directed evolution of the epidermal growth factor receptor extracellular domain for expression in yeast.
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Proteins
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2006
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1.03
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13
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Toward the development of an artificial cornea: improved stability of interpenetrating polymer networks.
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J Biomed Mater Res B Appl Biomater
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2011
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1.02
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14
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A dual-labeled knottin peptide for PET and near-infrared fluorescence imaging of integrin expression in living subjects.
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Bioconjug Chem
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2010
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1.00
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15
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An engineered knottin peptide labeled with 18F for PET imaging of integrin expression.
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Bioconjug Chem
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2009
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0.98
|
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16
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Development of hydrogel-based keratoprostheses: a materials perspective.
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Biotechnol Prog
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2008
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0.95
|
|
17
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PET Imaging of Integrin Positive Tumors Using F Labeled Knottin Peptides.
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Theranostics
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2011
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0.92
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18
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Beyond antibodies: using biological principles to guide the development of next-generation protein therapeutics.
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Curr Opin Biotechnol
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2013
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0.92
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19
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PET imaging of tumor neovascularization in a transgenic mouse model with a novel 64Cu-DOTA-knottin peptide.
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Cancer Res
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2010
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0.92
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20
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Developing therapeutic proteins by engineering ligand-receptor interactions.
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Trends Biotechnol
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2008
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0.91
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21
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Antagonistic VEGF variants engineered to simultaneously bind to and inhibit VEGFR2 and alphavbeta3 integrin.
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Proc Natl Acad Sci U S A
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2011
|
0.90
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|
22
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Engineering hepatocyte growth factor fragments with high stability and activity as Met receptor agonists and antagonists.
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Proc Natl Acad Sci U S A
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2011
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0.87
|
|
23
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Engineered knottin peptide enables noninvasive optical imaging of intracranial medulloblastoma.
|
Proc Natl Acad Sci U S A
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2013
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0.86
|
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24
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Functional mutation of multiple solvent-exposed loops in the Ecballium elaterium trypsin inhibitor-II cystine knot miniprotein.
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PLoS One
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2011
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0.84
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25
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Engineering knottins as novel binding agents.
|
Methods Enzymol
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2012
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0.84
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26
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Interrogating and predicting tolerated sequence diversity in protein folds: application to E. elaterium trypsin inhibitor-II cystine-knot miniprotein.
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PLoS Comput Biol
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2009
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0.83
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|
27
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A novel radiofluorinated agouti-related protein for tumor angiogenesis imaging.
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Amino Acids
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2012
|
0.83
|
|
28
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Elucidation of the interleukin-15 binding site on its alpha receptor by NMR.
|
Biochemistry
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2007
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0.83
|
|
29
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Engineering agatoxin, a cystine-knot peptide from spider venom, as a molecular probe for in vivo tumor imaging.
|
PLoS One
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2013
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0.82
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30
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A chemically cross-linked knottin dimer binds integrins with picomolar affinity and inhibits tumor cell migration and proliferation.
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J Am Chem Soc
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2014
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0.82
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31
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Bioactive interpenetrating polymer network hydrogels that support corneal epithelial wound healing.
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J Biomed Mater Res A
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2009
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0.82
|
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32
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Cystine-knot peptides engineered with specificities for α(IIb)β(3) or α(IIb)β(3) and α(v)β(3) integrins are potent inhibitors of platelet aggregation.
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J Mol Recognit
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2011
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0.82
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33
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111In-labeled cystine-knot peptides based on the Agouti-related protein for targeting tumor angiogenesis.
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J Biomed Biotechnol
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2012
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0.82
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34
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Cystine-knot peptides: emerging tools for cancer imaging and therapy.
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Expert Rev Proteomics
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2014
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0.80
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35
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Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies.
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J Clin Invest
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2016
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0.79
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36
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Applications of Yeast Surface Display for Protein Engineering.
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Methods Mol Biol
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2015
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0.79
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37
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Engineered epidermal growth factor mutants with faster binding on-rates correlate with enhanced receptor activation.
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FEBS Lett
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2011
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0.79
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38
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Discovery of improved EGF agonists using a novel in vitro screening platform.
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J Mol Biol
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2011
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0.78
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39
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Diffusion of protein through the human cornea.
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Ophthalmic Res
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2012
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0.75
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40
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SARS-CoV-2 Antibody Responses Correlate with Resolution of RNAemia But Are Short-Lived in Patients with Mild Illness.
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medRxiv
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2020
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0.75
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41
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Interpenetrating polymer network hydrogel scaffolds for artificial cornea periphery.
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J Mater Sci Mater Med
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2015
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0.75
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42
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Development of a Protease Biosensor Based on a Dimerization-Dependent Red Fluorescent Protein.
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ACS Chem Biol
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2017
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0.75
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