PubRank

Yulin Lam

Author PubWeight™ 20.16‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Retracted SphK1 regulates proinflammatory responses associated with endotoxin and polymicrobial sepsis. Science 2010 3.63
2 Synthesis and evaluation of sphingosine analogues as inhibitors of sphingosine kinases. J Med Chem 2009 1.08
3 CdpA is a Burkholderia pseudomallei cyclic di-GMP phosphodiesterase involved in autoaggregation, flagellum synthesis, motility, biofilm formation, cell invasion, and cytotoxicity. Infect Immun 2010 1.04
4 Synthesis and biological evaluation of polyenylpyrrole derivatives as anticancer agents acting through caspases-dependent apoptosis. J Med Chem 2010 0.99
5 Solid-phase synthesis of 3,4-dihydro-1H-pyrimidine-2-ones using sodium benzenesulfinate as a traceless linker. J Comb Chem 2005 0.91
6 Traceless solid-phase synthesis and biological evaluation of purine analogs as inhibitors of multidrug resistance protein 4. J Comb Chem 2007 0.87
7 Traceless solid-phase synthesis of substituted xanthines. J Comb Chem 2006 0.85
8 A facile solid-phase synthesis of 1,2,4,5-tetrasubstituted imidazoles using sodium benzenesulfinate as a traceless linker. J Comb Chem 2005 0.83
9 Synthesis and disulfide bond connectivity-activity studies of a kalata B1-inspired cyclopeptide against dengue NS2B-NS3 protease. Bioorg Med Chem 2009 0.82
10 Clinical and therapeutic relevance of PIM1 kinase in gastric cancer. Gastric Cancer 2011 0.81
11 Polyenylpyrrole derivatives inhibit NLRP3 inflammasome activation and inflammatory mediator expression by reducing reactive oxygen species production and mitogen-activated protein kinase activation. PLoS One 2013 0.78
12 Synthesis and in vitro evaluation of West Nile virus protease inhibitors based on the 2-{6-[2-(5-phenyl-4H-{1,2,4]triazol-3-ylsulfanyl)acetylamino]benzothiazol-2-ylsulfanyl}acetamide scaffold. ChemMedChem 2013 0.78
13 Synthesis of pyrazolo[5,1-d][1,2,3,5]tetrazine-4(3H)-ones. J Comb Chem 2010 0.78
14 Synthesis and in vitro evaluation of West Nile virus protease inhibitors based on the 1,3,4,5-tetrasubstituted 1H-pyrrol-2(5H)-one scaffold. ChemMedChem 2013 0.78
15 Discovery, synthesis, and in vitro evaluation of West Nile virus protease inhibitors based on the 9,10-dihydro-3H,4aH-1,3,9,10a-tetraazaphenanthren-4-one scaffold. ChemMedChem 2012 0.77
16 Fluorous oxime palladacycle: a precatalyst for carbon-carbon coupling reactions in aqueous and organic medium. J Org Chem 2012 0.77
17 Specificity and inhibitory mechanism of andrographolide and its analogues as antiasthma agents on NF-κB p50. J Nat Prod 2015 0.77
18 Synthesis of cyclic di-nucleotidic acids as potential inhibitors targeting diguanylate cyclase. Bioorg Med Chem 2010 0.76
19 Solid-phase synthesis of pyrazolines and isoxazolines with sodium benzenesulfinate as a traceless linker. Org Lett 2003 0.76
20 Generation of reactive oxygen species by polyenylpyrroles derivatives causes DNA damage leading to G2/M arrest and apoptosis in human oral squamous cell carcinoma cells. PLoS One 2013 0.76
21 Traceless solid-phase synthesis of heteroannulated 1,3-oxazin-6-ones. J Comb Chem 2009 0.75
22 Hydrogen peroxide enhances enterokinase-catalysed proteolytic cleavage of fusion protein. Recent Pat Biotechnol 2008 0.75
23 Traceless solid-phase synthesis of N1,N7-disubstituted purines. J Comb Chem 2005 0.75
24 [3+2] cycloaddition reactions in the solid-phase synthesis of 1,2,3-triazoles. Org Lett 2006 0.75
25 [3 + 2] Cycloaddition reactions in the synthesis of triazolo[4,5-b]pyridin-5-ones and pyrrolo[3,4-b]pyridin-2-ones. J Comb Chem 2008 0.75
26 Allylic and benzylic sp3 C-H oxidation in water. Org Biomol Chem 2014 0.75
27 Microwave-assisted synthesis of substituted 2-(benzylthio)imidazo[1,2a]pyrimidin-5-ones. J Comb Chem 2010 0.75
28 Regiospecific solid-phase strategy to N7-substituted purines and its application to 8-azapurines and [I]-condensed purines. J Comb Chem 2007 0.75
29 An efficient solid-phase synthesis of 3-substituted and 3,3-disubstituted 1,2-dialkylpyrazolidine-3,5-diones. Org Biomol Chem 2008 0.75
30 Synthesis of 2,4-disubstituted 5-aminoimidazoles using microwave irradiation. J Comb Chem 2006 0.75
31 Traceless solid-phase synthesis of nitrogen-containing heterocycles and their biological evaluations as inhibitors of neuronal sodium channels. J Comb Chem 2004 0.75
32 An efficient and expeditious synthesis of di- and monosubstituted 2-aminoimidazoles. J Comb Chem 2007 0.75
33 Traceless solid-phase synthesis of 6-amino- and 6-hydroxyimino-1,3,5-triazine-2,4-diones and 1,3,5-triazine-2,4,6-triones. J Comb Chem 2009 0.75
34 A versatile thiouronium-based solid-phase synthesis of 1,3,5-triazines. Chemistry 2011 0.75
35 Synthesis and the biological evaluation of 2-benzenesulfonylalkyl-5-substituted-sulfanyl-[1,3,4]-oxadiazoles as potential anti-hepatitis B virus agents. Antiviral Res 2006 0.75
36 A highly efficient solid-phase synthesis of 1,3-substituted xanthines. J Comb Chem 2005 0.75
37 Solid-phase synthesis of imidazo[1,2-a]pyridine using sodium benzenesulfinate as a traceless linker. Org Lett 2002 0.75