Serge Haan

Author PubWeight™ 34.48‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Principles of interleukin (IL)-6-type cytokine signalling and its regulation. Biochem J 2003 10.77
2 Activation of STAT3 by IL-6 and IL-10 in primary human macrophages is differentially modulated by suppressor of cytokine signaling 3. J Immunol 2003 1.92
3 Sustained IL-6/STAT-3 signaling in cholangiocarcinoma cells due to SOCS-3 epigenetic silencing. Gastroenterology 2006 1.68
4 Nucleocytoplasmic shuttling of persistently activated STAT3. J Cell Sci 2007 1.31
5 Suppressor of cytokine signaling-3 is recruited to the activated granulocyte-colony stimulating factor receptor and modulates its signal transduction. J Immunol 2002 1.29
6 Janus kinase (Jak) subcellular localization revisited: the exclusive membrane localization of endogenous Janus kinase 1 by cytokine receptor interaction uncovers the Jak.receptor complex to be equivalent to a receptor tyrosine kinase. J Biol Chem 2004 1.22
7 Perspectives for the use of structural information and chemical genetics to develop inhibitors of Janus kinases. J Cell Mol Med 2010 1.19
8 A new high affinity binding site for suppressor of cytokine signaling-3 on the erythropoietin receptor. Eur J Biochem 2002 1.12
9 The Jak1 SH2 domain does not fulfill a classical SH2 function in Jak/STAT signaling but plays a structural role for receptor interaction and up-regulation of receptor surface expression. J Biol Chem 2005 1.10
10 Interleukin-27 displays interferon-gamma-like functions in human hepatoma cells and hepatocytes. Hepatology 2009 1.07
11 Cell density dependent increase of constitutive signal transducers and activators of transcription 3 activity in melanoma cells is mediated by Janus kinases. Mol Cancer Res 2007 1.02
12 STAT3 is enriched in nuclear bodies. J Cell Sci 2003 1.00
13 The role of the inhibitors of interleukin-6 signal transduction SHP2 and SOCS3 for desensitization of interleukin-6 signalling. Biochem J 2004 0.98
14 Mechanisms of SOCS3 phosphorylation upon interleukin-6 stimulation. Contributions of Src- and receptor-tyrosine kinases. J Biol Chem 2005 0.98
15 Are STATS arginine-methylated? J Biol Chem 2005 0.95
16 Development of an IL-6 inhibitor based on the functional analysis of murine IL-6Ralpha(1). Chem Biol 2009 0.87
17 A fusion protein of the gp130 and interleukin-6Ralpha ligand-binding domains acts as a potent interleukin-6 inhibitor. J Biol Chem 2003 0.86
18 An unusual insertion in Jak2 is crucial for kinase activity and differentially affects cytokine responses. J Immunol 2009 0.85
19 The chemoattractants, IL-8 and formyl-methionyl-leucyl-phenylalanine, regulate granulocyte colony-stimulating factor signaling by inducing suppressor of cytokine signaling-1 expression. J Immunol 2004 0.85
20 Interleukin-27 acts on hepatic stellate cells and induces signal transducer and activator of transcription 1-dependent responses. Cell Commun Signal 2010 0.83
21 Determinants governing the potency of STAT3 activation via the individual STAT3-recruiting motifs of gp130. Cell Signal 2005 0.79
22 Bow to your partner for signaling. Nat Struct Mol Biol 2005 0.77
23 Co-immunoprecipitation protocol to investigate cytokine receptor-associated proteins, e.g., Janus kinases or other associated signaling proteins. Methods Mol Biol 2013 0.77
24 JAK2-V617F-induced MAPK activity is regulated by PI3K and acts synergistically with PI3K on the proliferation of JAK2-V617F-positive cells. JAKSTAT 2013 0.76
25 Software tools of the Computis European project to process mass spectrometry images. Eur J Mass Spectrom (Chichester, Eng) 2014 0.75