Published in ChemMedChem on April 06, 2010
High content screening of diverse compound libraries identifies potent modulators of tubulin dynamics. ACS Med Chem Lett (2014) 0.78
Inhibiting androgen receptor nuclear entry in castration-resistant prostate cancer. Nat Chem Biol (2016) 0.75
Toxicity and tissue distribution of magnetic nanoparticles in mice. Toxicol Sci (2005) 1.83
A robust small-molecule microarray platform for screening cell lysates. Chem Biol (2006) 1.52
Specific targeting, cell sorting, and bioimaging with smart magnetic silica core-shell nanomaterials. Small (2006) 1.39
Skeletal diversity via a branched pathway: efficient synthesis of 29 400 discrete, polycyclic compounds and their arraying into stock solutions. J Am Chem Soc (2002) 1.24
Orphan nuclear receptor estrogen-related receptor γ (ERRγ) is key regulator of hepatic gluconeogenesis. J Biol Chem (2012) 1.18
Hypoxia-induced methylation of a pontin chromatin remodeling factor. Proc Natl Acad Sci U S A (2011) 1.06
A practical procedure for producing silver nanocoated fabric and its antibacterial evaluation for biomedical applications. Chem Commun (Camb) (2007) 1.05
SUMOylation of pontin chromatin-remodeling complex reveals a signal integration code in prostate cancer cells. Proc Natl Acad Sci U S A (2007) 1.03
Transcriptional corepressor SMILE recruits SIRT1 to inhibit nuclear receptor estrogen receptor-related receptor gamma transactivation. J Biol Chem (2009) 1.02
Bioinspired polymerization of dopamine to generate melanin-like nanoparticles having an excellent free-radical-scavenging property. Biomacromolecules (2011) 1.02
Hypoxia induces PDK4 gene expression through induction of the orphan nuclear receptor ERRγ. PLoS One (2012) 1.02
Crystal structure of Tpa1 from Saccharomyces cerevisiae, a component of the messenger ribonucleoprotein complex. Nucleic Acids Res (2009) 1.00
Estrogen-related receptor γ (ERRγ) is a novel transcriptional regulator of phosphatidic acid phosphatase, LIPIN1, and inhibits hepatic insulin signaling. J Biol Chem (2011) 0.99
Expanding the functional group compatibility of small-molecule microarrays: discovery of novel calmodulin ligands. Angew Chem Int Ed Engl (2003) 0.99
Diversity-oriented synthesis of privileged benzopyranyl heterocycles from s-cis-enones. J Org Chem (2008) 0.96
Inverse agonist of nuclear receptor ERRγ mediates antidiabetic effect through inhibition of hepatic gluconeogenesis. Diabetes (2013) 0.90
Breast cancer metastasis suppressor 1 (BRMS1) is destabilized by the Cul3-SPOP E3 ubiquitin ligase complex. Biochem Biophys Res Commun (2011) 0.90
Concise and diversity-oriented synthesis of novel scaffolds embedded with privileged benzopyran motif. Chem Commun (Camb) (2006) 0.89
Bcl3-dependent stabilization of CtBP1 is crucial for the inhibition of apoptosis and tumor progression in breast cancer. Biochem Biophys Res Commun (2010) 0.89
Development of a cy3-labeled glucose bioprobe and its application in bioimaging and screening for anticancer agents. Angew Chem Int Ed Engl (2007) 0.89
Antitumor activity of HM781-36B, a highly effective pan-HER inhibitor in erlotinib-resistant NSCLC and other EGFR-dependent cancer models. Int J Cancer (2011) 0.89
A newly identified CG301269 improves lipid and glucose metabolism without body weight gain through activation of peroxisome proliferator-activated receptor alpha and gamma. Diabetes (2011) 0.88
Bio-inspired, melanin-like nanoparticles as a highly efficient contrast agent for T1-weighted magnetic resonance imaging. Biomacromolecules (2013) 0.87
Fluorescent probe for detection of fluoride in water and bioimaging in A549 human lung carcinoma cells. Chem Commun (Camb) (2009) 0.87
Natural polyphenols antagonize the antimyeloma activity of proteasome inhibitor bortezomib by direct chemical interaction. Br J Haematol (2009) 0.86
Biomimetic asymmetric total synthesis of (-)-laurefucin via an organoselenium-mediated intramolecular hydroxyetherification. J Am Chem Soc (2008) 0.86
Catalytic nickel nanoparticles embedded in a mesoporous metal-organic framework. Chem Commun (Camb) (2010) 0.85
De novo analysis of protein N-terminal sequence utilizing MALDI signal enhancing derivatization with Br signature. Anal Bioanal Chem (2011) 0.85
Practical solid-phase parallel synthesis of Delta(5)-2-oxopiperazines via N-acyliminium ion cyclization. J Comb Chem (2007) 0.85
Enhanced efficacy of 7-hydroxy-3-methoxycadalene via glycosylation in in vivo xenograft study. Bioorg Med Chem Lett (2007) 0.85
Discovery and target identification of an antiproliferative agent in live cells using fluorescence difference in two-dimensional gel electrophoresis. Angew Chem Int Ed Engl (2012) 0.85
Privileged structures: efficient chemical "navigators" toward unexplored biologically relevant chemical spaces. J Am Chem Soc (2014) 0.84
Emission wavelength prediction of a full-color-tunable fluorescent core skeleton, 9-aryl-1,2-dihydropyrrolo[3,4-b]indolizin-3-one. J Am Chem Soc (2011) 0.83
Rational perturbation of the fluorescence quantum yield in emission-tunable and predictable fluorophores (Seoul-Fluors) by a facile synthetic method involving C-H activation. Angew Chem Int Ed Engl (2014) 0.83
Optimization of AAV expression cassettes to improve packaging capacity and transgene expression in neurons. Mol Brain (2014) 0.83
Chemistry as a prism: a review of light-emitting materials having tunable emission wavelengths. Chem Asian J (2009) 0.83
Synthesis and in vitro photodynamic activities of water-soluble fluorinated tetrapyridylporphyrins as tumor photosensitizers. Bioorg Med Chem Lett (2007) 0.83
A two-photon tracer for glucose uptake. Angew Chem Int Ed Engl (2009) 0.83
Ethanol and reactive species increase basal sequence heterogeneity of hepatitis C virus and produce variants with reduced susceptibility to antivirals. PLoS One (2011) 0.83
Repeated aerosol delivery of carboxyl-terminal modulator protein suppresses tumor in the lungs of K-rasLA1 mice. Am J Respir Crit Care Med (2009) 0.82
Abc amino acids: design, synthesis, and properties of new photoelastic amino acids. J Org Chem (2006) 0.82
An efficient one-step synthesis of heterobiaryl pyrazolo[3,4-b]pyridines via indole ring opening. Org Lett (2009) 0.82
Effect of saikosaponin-A, a triterpenoid glycoside, isolated from Bupleurum falcatum on experimental allergic asthma. Phytother Res (2002) 0.82
Efficient discovery of selective small molecule agonists of estrogen-related receptor gamma using combinatorial approach. J Comb Chem (2009) 0.81
Combinatorial discovery of full-color-tunable emissive fluorescent probes using a single core skeleton, 1,2-dihydropyrrolo[3,4-beta]indolizin-3-one. J Am Chem Soc (2008) 0.81
One-dimensional organometallic molecular wires via assembly of Rh(CO)2Cl(amine): chemical control of interchain distances and optical properties. J Am Chem Soc (2009) 0.81
Regioselective synthesis of tetrasubstituted pyrroles by 1,3-dipolar cycloaddition and spontaneous decarboxylation. Org Lett (2009) 0.81
Polo-like kinase 2 gene expression is regulated by the orphan nuclear receptor estrogen receptor-related receptor gamma (ERRgamma). Biochem Biophys Res Commun (2007) 0.81
Development of fluorescent glucose bioprobes and their application on real-time and quantitative monitoring of glucose uptake in living cells. Chemistry (2011) 0.81
A Seoul-Fluor-based bioprobe for lipid droplets and its application in image-based high throughput screening. Chem Commun (Camb) (2012) 0.80
Diastereoselective synthesis of polycyclic acetal-fused pyrano[3,2-c]pyran-5(2H)-one derivatives. J Org Chem (2009) 0.80
A synthetic route to highly substituted 1,2,3,4-tetrahydroisoquinolines via Yb(OTf)3 -catalyzed diastereoselective ring opening of bridged oxazolidines: asymmetric synthesis of 2-azapodophyllotoxin. Chemistry (2011) 0.80
Discovery of a novel Her-1/Her-2 dual tyrosine kinase inhibitor for the treatment of Her-1 selective inhibitor-resistant non-small cell lung cancer. J Med Chem (2009) 0.80
Crystallization and preliminary X-ray diffraction analysis of importin-alpha complexed with NLS peptidomimetics. Biochim Biophys Acta (2005) 0.79
A selective Seoul-Fluor-based bioprobe, SfBP, for vaccinia H1-related phosphatase--a dual-specific protein tyrosine phosphatase. Chem Commun (Camb) (2012) 0.79
Lentiviral vector-mediated shRNA against AIMP2-DX2 suppresses lung cancer cell growth through blocking glucose uptake. Mol Cells (2012) 0.79
Optimization of Seoul-Fluor-based lipid droplet bioprobes and their application in microalgae for bio-fuel study. Mol Biosyst (2013) 0.79
Discovery of carbohybrid-based 2-aminopyrimidine analogues as a new class of rapid-acting antimalarial agents using image-based cytological profiling assay. J Med Chem (2014) 0.79
Estrogen-related receptor gamma induces cardiac hypertrophy by activating GATA4. J Mol Cell Cardiol (2013) 0.79
Synthesis and library construction of privileged tetra-substituted Δ5-2-oxopiperazine as β-turn structure mimetics. ACS Comb Sci (2013) 0.79
Antiallergic activity of a disaccharide isolated from Sanguisorba officinalis. Phytother Res (2004) 0.79
Efficient parallel synthesis of privileged benzopyranylpyrazoles via regioselective condensation of beta-keto aldehydes with hydrazines. J Comb Chem (2009) 0.79
Surface modification for small-molecule microarrays and its application to the discovery of a tyrosinase inhibitor. Mol Biosyst (2010) 0.78
Reversible interpenetration in a metal-organic framework triggered by ligand removal and addition. Angew Chem Int Ed Engl (2012) 0.78
Construction of a polyheterocyclic benzopyran library with diverse core skeletons through diversity-oriented synthesis pathway. J Comb Chem (2010) 0.78
Synthesis and biological evaluation of pyrimidine-based dual inhibitors of human epidermal growth factor receptor 1 (HER-1) and HER-2 tyrosine kinases. J Med Chem (2012) 0.78
Anti-obesity agents: a focused review on the structural classification of therapeutic entities. Curr Top Med Chem (2009) 0.78
A design strategy for drug-like polyheterocycles with privileged substructures for discovery of specific small-molecule modulators. Chem Commun (Camb) (2011) 0.78
From noncovalent to covalent bonds: a paradigm shift in target protein identification. Mol Biosyst (2013) 0.78
Surface Selective Deposition of PMMA on Layered Double Hydroxide Nanocrystals Immobilized on Solid Substrates. Adv Mater (2009) 0.78
Unique photophysical properties of 9-styryl-1,2-dihydropyrrolo[3,4-β]indolizin-3-one and its efficient synthesis via direct C-H activation. Org Biomol Chem (2015) 0.78
Synthesis and biological evaluation of α-galactosylceramide analogues with heteroaromatic rings and varying positions of a phenyl group in the sphingosine backbone. J Med Chem (2013) 0.77
Impact of molecular charge on GLUT-specific cellular uptake of glucose bioprobes and in vivo application of the glucose bioprobe, GB2-Cy3. Chem Commun (Camb) (2014) 0.77
Nonspecific protein labeling of photoaffinity linkers correlates with their molecular shapes in living cells. Chem Commun (Camb) (2016) 0.76
Pharmacophore-based strategy for the development of general and specific scFv biosensors for abused antibiotics. Bioconjug Chem (2010) 0.76
A nonthiazolidinedione peroxisome proliferator-activated receptor α/γ dual agonist CG301360 alleviates insulin resistance and lipid dysregulation in db/db mice. Mol Pharmacol (2010) 0.76
Privileged substructure-based diversity-oriented synthesis pathway for diverse pyrimidine-embedded polyheterocycles. Org Lett (2013) 0.76
Antidiabetic and antiobesity effects of Ampkinone (6f), a novel small molecule activator of AMP-activated protein kinase. J Med Chem (2010) 0.76
Small molecule microarray: functional-group specific immobilization of small molecules. Methods Mol Biol (2010) 0.76
Protein kinase C-δ-mediated recycling of active KIT in colon cancer. Clin Cancer Res (2013) 0.76
A high-content screening platform with fluorescent chemical probes for the discovery of first-in-class therapeutics. Chem Commun (Camb) (2016) 0.75
Differences in styles of writing about a tragic public event over time. Psychol Rep (2004) 0.75
An analysis of linguistic styles by inferred age in tv dramas. Psychol Rep (2006) 0.75
Phenotypic screening to identify small-molecule enhancers for glucose uptake: target identification and rational optimization of their efficacy. Angew Chem Int Ed Engl (2014) 0.75
Exploiting the mechanism of cellular glucose uptake to develop an image-based high-throughput screening system in living cells. Chem Commun (Camb) (2013) 0.75
[The effect of treadmill exercise on ischemic neuronal injury in the stroke animal model: potentiation of cerebral vascular integrity]. J Korean Acad Nurs (2011) 0.75
Writing styles of a Korean sample by age: an exploratory study. Psychol Rep (2010) 0.75
Passivated ambipolar black phosphorus transistors. Nanoscale (2016) 0.75
Ratiometric analysis of zidovudine (ZDV) incorporation by reverse transcriptases or polymerases via bio-orthogonal click chemistry. Chem Commun (Camb) (2011) 0.75
Integrated Magneto-Chemical Sensor For On-Site Food Allergen Detection. ACS Nano (2017) 0.75