Published in Clin Sci (Lond) on March 30, 2010
The human adenocarcinoma-associated gene, AGR2, induces expression of amphiregulin through Hippo pathway co-activator YAP1 activation. J Biol Chem (2011) 1.31
Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2. Development (2012) 1.08
Elevated level of anterior gradient-2 in pancreatic juice from patients with pre-malignant pancreatic neoplasia. Mol Cancer (2010) 1.06
AGR2 gene function requires a unique endoplasmic reticulum localization motif. J Biol Chem (2011) 0.97
A highly sensitive targeted mass spectrometric assay for quantification of AGR2 protein in human urine and serum. J Proteome Res (2013) 0.94
Evaluation of midkine and anterior gradient 2 in a multimarker panel for the detection of ovarian cancer. J Exp Clin Cancer Res (2010) 0.88
Optimizing molecular-targeted therapies in ovarian cancer: the renewed surge of interest in ovarian cancer biomarkers and cell signaling pathways. J Oncol (2012) 0.88
Evaluation of the adenocarcinoma-associated gene AGR2 and the intestinal stem cell marker LGR5 as biomarkers in colorectal cancer. Int J Mol Sci (2012) 0.86
Loss of anterior gradient 2 (Agr2) expression results in hyperplasia and defective lineage maturation in the murine stomach. J Biol Chem (2012) 0.85
Anterior gradient protein 2 (AGR2) is an independent prognostic factor in ovarian high-grade serous carcinoma. Virchows Arch (2012) 0.83
The metastasis-inducing protein AGR2 is O-glycosylated upon secretion from mammary epithelial cells. Mol Cell Biochem (2015) 0.78
AGR3 in breast cancer: prognostic impact and suitable serum-based biomarker for early cancer detection. PLoS One (2015) 0.76
Tumor-secreted anterior gradient-2 binds to VEGF and FGF2 and enhances their activities by promoting their homodimerization. Oncogene (2017) 0.75
Tazarotene-induced gene 1 (TIG1) expression in prostate carcinomas and its relationship to tumorigenicity. J Natl Cancer Inst (2002) 2.41
Prognostic significance of the metastasis-associated protein osteopontin in human breast cancer. Cancer Res (2002) 1.99
Human homologue of cement gland protein, a novel metastasis inducer associated with breast carcinomas. Cancer Res (2005) 1.94
Multicellular spheroids in ovarian cancer metastases: Biology and pathology. Gynecol Oncol (2009) 1.82
Neutrophil gelatinase-associated lipocalin (NGAL) an early-screening biomarker for ovarian cancer: NGAL is associated with epidermal growth factor-induced epithelio-mesenchymal transition. Int J Cancer (2007) 1.63
Nuclear factor kappa B regulation of proinflammatory cytokines in human gestational tissues in vitro. Biol Reprod (2002) 1.63
The regulation and role of osteopontin in malignant transformation and cancer. Cytokine Growth Factor Rev (2006) 1.59
Rat Muc4 (sialomucin complex) reduces binding of anti-ErbB2 antibodies to tumor cell surfaces, a potential mechanism for herceptin resistance. Int J Cancer (2002) 1.50
Expression and splicing of the unfolded protein response gene XBP-1 are significantly associated with clinical outcome of endocrine-treated breast cancer. Int J Cancer (2008) 1.48
Induction of metastasis by S100P in a rat mammary model and its association with poor survival of breast cancer patients. Cancer Res (2006) 1.42
ERBB2 up-regulates S100A4 and several other prometastatic genes in medulloblastoma. Cancer Res (2003) 1.41
Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis. PLoS One (2013) 1.36
Association of S100A4 and osteopontin with specific prognostic factors and survival of patients with minimally invasive breast cancer. Clin Cancer Res (2006) 1.33
Common origins of MDA-MB-435 cells from various sources with those shown to have melanoma properties. Clin Exp Metastasis (2004) 1.29
Alpha2beta1 integrin affects metastatic potential of ovarian carcinoma spheroids by supporting disaggregation and proteolysis. J Carcinog (2007) 1.25
The metastasis-associated anterior gradient 2 protein is correlated with poor survival of breast cancer patients. Am J Pathol (2009) 1.19
Stanniocalcin 2 is an estrogen-responsive gene coexpressed with the estrogen receptor in human breast cancer. Cancer Res (2002) 1.18
Ets gene PEA3 cooperates with beta-catenin-Lef-1 and c-Jun in regulation of osteopontin transcription. J Biol Chem (2004) 1.18
N-Acetyl-cysteine inhibits phospholipid metabolism, proinflammatory cytokine release, protease activity, and nuclear factor-kappaB deoxyribonucleic acid-binding activity in human fetal membranes in vitro. J Clin Endocrinol Metab (2003) 1.18
Direct actions of urotensin II on the heart: implications for cardiac fibrosis and hypertrophy. Circ Res (2003) 1.18
Release and regulation of leptin, resistin and adiponectin from human placenta, fetal membranes, and maternal adipose tissue and skeletal muscle from normal and gestational diabetes mellitus-complicated pregnancies. J Endocrinol (2005) 1.17
Single-molecule imaging and fluorescence lifetime imaging microscopy show different structures for high- and low-affinity epidermal growth factor receptors in A431 cells. Biophys J (2007) 1.15
Alpha(v)beta(6) integrin-A marker for the malignant potential of epithelial ovarian cancer. J Histochem Cytochem (2002) 1.15
Sulfasalazine and BAY 11-7082 interfere with the nuclear factor-kappa B and I kappa B kinase pathway to regulate the release of proinflammatory cytokines from human adipose tissue and skeletal muscle in vitro. Endocrinology (2004) 1.13
Ovarian cancer cell invasiveness is associated with discordant exosomal sequestration of Let-7 miRNA and miR-200. J Transl Med (2014) 1.13
High-level expression of cutaneous fatty acid-binding protein in prostatic carcinomas and its effect on tumorigenicity. Oncogene (2003) 1.13
Screening for biomarkers predictive of gestational diabetes mellitus. Acta Diabetol (2008) 1.09
Adenoviral-directed expression of the type 1A angiotensin receptor promotes cardiomyocyte hypertrophy via transactivation of the epidermal growth factor receptor. Circ Res (2002) 1.08
Expression of S100A4 protein is associated with metastasis and reduced survival in human bladder cancer. J Pathol (2002) 1.07
Hypoxia-induced changes in the bioactivity of cytotrophoblast-derived exosomes. PLoS One (2013) 1.05
Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. J Transl Med (2014) 1.02
Joining S100 proteins and migration: for better or for worse, in sickness and in health. Cell Mol Life Sci (2013) 1.02
The basic C-terminal amino acids of calcium-binding protein S100A4 promote metastasis. Carcinogenesis (2008) 1.02
Sex hormones and cardiomyopathic phenotype induced by cardiac beta 2-adrenergic receptor overexpression. Endocrinology (2003) 1.00
Mice lacking three myeloid colony-stimulating factors (G-CSF, GM-CSF, and M-CSF) still produce macrophages and granulocytes and mount an inflammatory response in a sterile model of peritonitis. J Immunol (2007) 1.00
Self-association of calcium-binding protein S100A4 and metastasis. J Biol Chem (2009) 0.97
Mutually antagonistic actions of S100A4 and S100A1 on normal and metastatic phenotypes. Oncogene (2005) 0.95
The crystal structure at 2A resolution of the Ca2+ -binding protein S100P. J Mol Biol (2003) 0.95
Statistical association of basal cell keratins with metastasis-inducing proteins in a prognostically unfavorable group of sporadic breast cancers. Am J Pathol (2011) 0.95
Advanced glycation endproducts mediate pro-inflammatory actions in human gestational tissues via nuclear factor-kappaB and extracellular signal-regulated kinase 1/2. J Endocrinol (2007) 0.95
Significance of the Fanconi anemia FANCD2 protein in sporadic and metastatic human breast cancer. Am J Pathol (2010) 0.94
Matrix metalloproteinase-3 and coronary remodelling: implications for unstable coronary disease. Cardiovasc Res (2007) 0.94
Regulation of proinflammatory cytokines in human gestational tissues by peroxisome proliferator-activated receptor-gamma: effect of 15-deoxy-Delta(12,14)-PGJ(2) and troglitazone. J Clin Endocrinol Metab (2002) 0.94
5 Beta-dihydroprogesterone and steroid 5 beta-reductase decrease in association with human parturition at term. Mol Hum Reprod (2005) 0.94
Regulation of phospholipase isozymes by nuclear factor-kappaB in human gestational tissues in vitro. J Clin Endocrinol Metab (2004) 0.93
Proteomic analysis and characterisation of human cervico-vaginal fluid proteins. Aust N Z J Obstet Gynaecol (2007) 0.93
Cross talk between corticosteroids and alpha-adrenergic signalling augments cardiomyocyte hypertrophy: a possible role for SGK1. Cardiovasc Res (2006) 0.93
RanGTPase: a candidate for Myc-mediated cancer progression. J Natl Cancer Inst (2013) 0.93
Transfection of S100A4 produces metastatic variants of an orthotopic model of bladder cancer. Am J Pathol (2002) 0.93
Release of proinflammatory cytokines and 8-isoprostane from placenta, adipose tissue, and skeletal muscle from normal pregnant women and women with gestational diabetes mellitus. J Clin Endocrinol Metab (2004) 0.92
Why do membranes rupture at term? Evidence of increased cellular apoptosis in the supracervical fetal membranes. Am J Obstet Gynecol (2007) 0.92
Ran is a potential therapeutic target for cancer cells with molecular changes associated with activation of the PI3K/Akt/mTORC1 and Ras/MEK/ERK pathways. Clin Cancer Res (2011) 0.92
ATP depletion induces translocation of STIM1 to puncta and formation of STIM1-ORAI1 clusters: translocation and re-translocation of STIM1 does not require ATP. Pflugers Arch (2008) 0.92
The heparan sulfate co-receptor and the concentration of fibroblast growth factor-2 independently elicit different signalling patterns from the fibroblast growth factor receptor. Cell Commun Signal (2010) 0.91
Gastric HER2 Testing Study (GaTHER): an evaluation of gastric/gastroesophageal junction cancer testing accuracy in Australia. Am J Surg Pathol (2012) 0.91
Metastasis-promoting anterior gradient 2 protein has a dimeric thioredoxin fold structure and a role in cell adhesion. J Mol Biol (2012) 0.90
Asymmetric mode of Ca²⁺-S100A4 interaction with nonmuscle myosin IIA generates nanomolar affinity required for filament remodeling. Structure (2012) 0.90
The role of gangliosides in brain development and the potential benefits of perinatal supplementation. Nutr Res (2013) 0.90
Strategies for revealing lower abundance proteins in two-dimensional protein maps. J Chromatogr B Analyt Technol Biomed Life Sci (2005) 0.90
Genetic segregation of inflammatory lung disease and autoimmune disease severity in SHIP-1-/- mice. J Immunol (2011) 0.90
The effect of pre-existing maternal obesity on the placental proteome: two-dimensional difference gel electrophoresis coupled with mass spectrometry. J Mol Endocrinol (2012) 0.89
Repression of oxidant-induced nuclear factor-kappaB activity mediates placental cytokine responses in gestational diabetes. J Clin Endocrinol Metab (2004) 0.89
Adrenomedullin expression in rat uterus is correlated with plasma estradiol. Am J Physiol Endocrinol Metab (2002) 0.89
Plasminogen fragmentation and increased production of extracellular matrix-degrading proteinases are associated with serous epithelial ovarian cancer progression. Gynecol Oncol (2004) 0.89
The C-terminal region of S100A4 is important for its metastasis-inducing properties. Oncogene (2005) 0.89
BRCA1 suppresses osteopontin-mediated breast cancer. J Biol Chem (2006) 0.89
Evaluation of midkine and anterior gradient 2 in a multimarker panel for the detection of ovarian cancer. J Exp Clin Cancer Res (2010) 0.88
Complex CGH alterations on chromosome arm 8p at candidate tumor suppressor gene loci in breast cancer cell lines. Cancer Genet Cytogenet (2005) 0.88
The cryptome: a subset of the proteome, comprising cryptic peptides with distinct bioactivities. Drug Discov Today (2006) 0.88
S100P dissociates myosin IIA filaments and focal adhesion sites to reduce cell adhesion and enhance cell migration. J Biol Chem (2012) 0.87
The expression of C-FABP and PPARγ and their prognostic significance in prostate cancer. Int J Oncol (2013) 0.87
Interaction of metastasis-inducing S100A4 protein in vivo by fluorescence lifetime imaging microscopy. Eur Biophys J (2004) 0.87
2D-DIGE to identify proteins associated with gestational diabetes in omental adipose tissue. J Endocrinol (2013) 0.87
Assessing HER2 amplification in breast cancer: findings from the Australian In Situ Hybridization Program. Breast Cancer Res Treat (2012) 0.86
Increased chemerin concentrations in fetuses of obese mothers and correlation with maternal insulin sensitivity. J Matern Fetal Neonatal Med (2012) 0.85
The interplay of the interleukin 1 system in pregnancy and labor. Reprod Sci (2013) 0.84
2D-PAGE of ovarian cancer: analysis of soluble and insoluble fractions using medium-range immobilized pH gradients. Biochem Biophys Res Commun (2011) 0.83
Proteomic analysis of hyperoxia-induced responses in the human choriocarcinoma cell line JEG-3. Proteomics (2004) 0.83
The role of endocannabinoids in pregnancy. Reproduction (2013) 0.83
Effects of life event stress and social support on the odds of a >or= 2 cm breast cancer. Cancer Causes Control (2008) 0.82