N B La Thangue

Author PubWeight™ 78.45‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 p300/CBP proteins: HATs for transcriptional bridges and scaffolds. J Cell Sci 2001 5.74
2 Adenovirus E1a prevents the retinoblastoma gene product from complexing with a cellular transcription factor. Nature 1991 4.62
3 Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein. Nature 1995 3.32
4 Cyclin A and the retinoblastoma gene product complex with a common transcription factor. Nature 1991 3.15
5 A new component of the transcription factor DRTF1/E2F. Nature 1993 2.65
6 Functional synergy between DP-1 and E2F-1 in the cell cycle-regulating transcription factor DRTF1/E2F. EMBO J 1993 2.55
7 Adenovirus E1a prevents the retinoblastoma gene product from repressing the activity of a cellular transcription factor. EMBO J 1992 2.11
8 A novel cofactor for p300 that regulates the p53 response. Mol Cell 1999 2.11
9 Acetylation control of the retinoblastoma tumour-suppressor protein. Nat Cell Biol 2001 2.05
10 An adenovirus E1A-like transcription factor is regulated during the differentiation of murine embryonal carcinoma stem cells. Cell 1987 1.96
11 DP and E2F proteins: coordinating transcription with cell cycle progression. Curr Opin Cell Biol 1994 1.94
12 Transcriptional repression by the Rb-related protein p107. Mol Biol Cell 1993 1.72
13 Functional interaction between nucleosome assembly proteins and p300/CREB-binding protein family coactivators. Mol Cell Biol 2000 1.55
14 HDAC inhibitor-based therapies and haematological malignancy. Ann Oncol 2009 1.45
15 Control of E2F activity by p21Waf1/Cip1. Oncogene 1999 1.41
16 Promoter specificity and stability control of the p53-related protein p73. Oncogene 1999 1.36
17 Lysine methylation regulates the pRb tumour suppressor protein. Oncogene 2010 1.30
18 Regulation of E2F transcription by cyclin E-Cdk2 kinase mediated through p300/CBP co-activators. Nat Cell Biol 2000 1.28
19 DP-1: a cell cycle-regulated and phosphorylated component of transcription factor DRTF1/E2F which is functionally important for recognition by pRb and the adenovirus E4 orf 6/7 protein. EMBO J 1994 1.24
20 Role of LXCXE motif-dependent interactions in the activity of the retinoblastoma protein. Oncogene 2001 1.16
21 Nuclear accumulation of the E2F heterodimer regulated by subunit composition and alternative splicing of a nuclear localization signal. J Cell Sci 1996 1.13
22 A TPR motif cofactor contributes to p300 activity in the p53 response. Mol Cell 2001 1.12
23 Functional interplay between p53 and E2F through co-activator p300. Oncogene 1998 1.10
24 Isolation of cDNA clones derived from a cellular gene transcriptionally induced by herpes simplex virus. Nucleic Acids Res 1986 1.10
25 Functional conservation of the cell cycle-regulating transcription factor DRTF1/E2F and its pathway of control in Drosophila melanogaster. J Cell Sci 1995 1.06
26 Apoptotic and growth-promoting activity of E2F modulated by MDM2. Mol Cell Biol 2000 1.06
27 Functional interaction between DP-1 and p53. Mol Cell Biol 1996 1.06
28 Diversity within the pRb pathway: is there a code of conduct? Oncogene 2012 1.03
29 Molecular and functional characterisation of E2F-5, a new member of the E2F family. Oncogene 1995 1.02
30 Multicomponent differentiation-regulated transcription factors in F9 embryonal carcinoma stem cells. Mol Cell Biol 1991 0.99
31 Cellular proteins expressed in herpes simplex virus transformed cells also accumulate on herpes simplex virus infection. EMBO J 1985 0.99
32 Integration of a growth-suppressing BTB/POZ domain protein with the DP component of the E2F transcription factor. EMBO J 1999 0.99
33 Regulation of E2F4 mitogenic activity during terminal differentiation by its heterodimerization partners for nuclear translocation. Cancer Res 1998 0.98
34 A new component of the transcription factor DRTF1/E2F. Nature 1993 0.98
35 Proto-oncogenic properties of the DP family of proteins. Oncogene 1995 0.97
36 A multiplicity of differentiation-regulated ATF site-binding activities in embryonal carcinoma cells with distinct sequence and promoter specificities. New Biol 1990 0.97
37 E2F-1 regulation by an unusual DNA damage-responsive DP partner subunit. Cell Death Differ 2010 0.96
38 A new member of the DP family, DP-3, with distinct protein products suggests a regulatory role for alternative splicing in the cell cycle transcription factor DRTF1/E2F. Oncogene 1995 0.96
39 Distinct mechanisms of nuclear accumulation regulate the functional consequence of E2F transcription factors. J Cell Sci 1997 0.95
40 Hypoxia-driven cell motility reflects the interplay between JMY and HIF-1α. Oncogene 2011 0.93
41 Transcriptional induction of cellular gene expression during lytic infection with herpes simplex virus. Biosci Rep 1986 0.91
42 A developmentally regulated and tissue-dependent transcription factor complexes with the retinoblastoma gene product. EMBO J 1991 0.90
43 Molecular characterization of Xenopus laevis DP proteins. Mol Biol Cell 1994 0.89
44 A regulatory circuit that involves HR23B and HDAC6 governs the biological response to HDAC inhibitors. Cell Death Differ 2013 0.89
45 Apoptosis induced in mammalian cells by small peptides that functionally antagonize the Rb-regulated E2F transcription factor. Nat Biotechnol 1997 0.87
46 A functionally distinct member of the DP family of E2F subunits. Oncogene 2006 0.86
47 The herpes simplex virus type 1 immediate-early protein ICP27 is obligately required for the accumulation of a cellular protein during viral infection. Virology 1989 0.86
48 A structural similarity between mammalian and yeast transcription factors for cell-cycle-regulated genes. Trends Cell Biol 1993 0.84
49 Monoclonal antibodies to herpes simplex virus type 1 glycoproteins show that epitope location influences virus neutralization. J Med Virol 1984 0.82
50 The regulation of cellular transcription by Simian virus 40 large T-antigen. Proc R Soc Lond B Biol Sci 1985 0.80
51 Control of gene expression and the cell cycle. Essays Biochem 2001 0.79
52 The predominant E2F complex in human primary haemopoietic cells and in AML blasts contains E2F-4, DP-1 and p130. Br J Haematol 1997 0.78
53 The human Mr 90,000 heat shock protein and the Escherichia coli Lon protein share an antigenic determinant. Comp Biochem Physiol B 1987 0.78
54 Signal transduction blockade and cancer: combination therapy or multi-targeted inhibitors? Ann Oncol 2004 0.77
55 Genomic structure and developmental expression of the mouse cell cycle regulatory transcription factor DP1. Oncogene 1996 0.76
56 Chromatin research gathers pace. Trends Cell Biol 1997 0.76
57 Cellular polypeptides overexpressed after herpes simplex infection permit virus subtyping and may help diagnose cervical cancer. Genitourin Med 1988 0.75
58 DRTFI/E2F transcription factor: an integrator of cell-cycle events with the transcriptional apparatus. Biochem Soc Trans 1993 0.75