Published in J Nat Prod on February 26, 2010
Screening for antimalarial and acetylcholinesterase inhibitory activities of some Iranian seaweeds. Res Pharm Sci (2013) 0.94
Antiprotozoal activities of organic extracts from French marine seaweeds. Mar Drugs (2011) 0.92
Bromophycolide A targets heme crystallization in the human malaria parasite Plasmodium falciparum. ChemMedChem (2011) 0.88
The structural diversity and promise of antiparasitic marine invertebrate-derived small molecules. Curr Opin Biotechnol (2010) 0.84
Unusual antimalarial meroditerpenes from tropical red macroalgae. Bioorg Med Chem Lett (2010) 0.84
Bioactivity of seagrass against the dengue fever mosquito Aedes aegypti larvae. Asian Pac J Trop Biomed (2012) 0.81
Bromophycoic acids: bioactive natural products from a Fijian red alga Callophycus sp. J Org Chem (2012) 0.80
Assessment of dual life stage antiplasmodial activity of british seaweeds. Mar Drugs (2013) 0.78
High content live cell imaging for the discovery of new antimalarial marine natural products. BMC Infect Dis (2012) 0.77
A short asymmetric route to the bromophycolide A and D skeleton. Org Lett (2011) 0.75
Red algal bromophenols as glucose 6-phosphate dehydrogenase inhibitors. Mar Drugs (2013) 0.75
Pharmacokinetics, metabolism, and in vivo efficacy of the antimalarial natural product bromophycolide A. ACS Med Chem Lett (2013) 0.75
Simple and inexpensive fluorescence-based technique for high-throughput antimalarial drug screening. Antimicrob Agents Chemother (2004) 7.51
Marine natural products. Nat Prod Rep (2009) 3.41
BMS-247550: a novel epothilone analog with a mode of action similar to paclitaxel but possessing superior antitumor efficacy. Clin Cancer Res (2001) 2.64
Desorption electrospray ionization mass spectrometry reveals surface-mediated antifungal chemical defense of a tropical seaweed. Proc Natl Acad Sci U S A (2009) 1.86
In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis. Antimicrob Agents Chemother (2005) 1.81
Antineoplastic diterpene-benzoate macrolides from the Fijian red alga Callophycus serratus. Org Lett (2005) 1.73
Bromophycolides C-I from the Fijian red alga Callophycus serratus. J Nat Prod (2006) 1.43
Callophycoic acids and callophycols from the Fijian red alga Callophycus serratus. J Org Chem (2007) 1.29
Antimalarial bromophycolides J-Q from the Fijian red alga Callophycus serratus. J Org Chem (2009) 1.19
Opposing effects of native and exotic herbivores on plant invasions. Science (2006) 4.29
A competitive ELISA to detect brevetoxins from Karenia brevis (formerly Gymnodinium breve) in seawater, shellfish, and mammalian body fluid. Environ Health Perspect (2002) 4.14
Herbivore species richness and feeding complementarity affect community structure and function on a coral reef. Proc Natl Acad Sci U S A (2008) 2.95
A systematic map of genetic variation in Plasmodium falciparum. PLoS Pathog (2006) 2.92
Herbivore vs. nutrient control of marine primary producers: context-dependent effects. Ecology (2006) 2.90
Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis. Antimicrob Agents Chemother (2007) 2.80
Chemically rich seaweeds poison corals when not controlled by herbivores. Proc Natl Acad Sci U S A (2010) 2.54
Discovery of anticancer agents of diverse natural origin. Pure Appl Chem (2009) 2.00
Desorption electrospray ionization mass spectrometry reveals surface-mediated antifungal chemical defense of a tropical seaweed. Proc Natl Acad Sci U S A (2009) 1.86
Consumer diversity interacts with prey defenses to drive ecosystem function. Ecology (2013) 1.82
Macroalgal terpenes function as allelopathic agents against reef corals. Proc Natl Acad Sci U S A (2011) 1.82
In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis. Antimicrob Agents Chemother (2005) 1.81
Antineoplastic diterpene-benzoate macrolides from the Fijian red alga Callophycus serratus. Org Lett (2005) 1.73
Nucleosome landscape and control of transcription in the human malaria parasite. Genome Res (2010) 1.70
Structure-activity relationships for a series of quinoline-based compounds active against replicating and nonreplicating Mycobacterium tuberculosis. J Med Chem (2009) 1.69
Silvestrol and episilvestrol, potential anticancer rocaglate derivatives from Aglaia silvestris. J Org Chem (2004) 1.69
Marine actinomycetes: a new source of compounds against the human malaria parasite. PLoS One (2008) 1.67
Chemical cues induce consumer-specific defenses in a bloom-forming marine phytoplankton. Proc Natl Acad Sci U S A (2007) 1.62
Thiosemicarbazones, semicarbazones, dithiocarbazates and hydrazide/hydrazones: anti-Mycobacterium tuberculosis activity and cytotoxicity. Eur J Med Chem (2010) 1.62
A microbiological assessment of novel nitrofuranylamides as anti-tuberculosis agents. J Antimicrob Chemother (2008) 1.58
Marine actinomycetes: an ongoing source of novel bioactive metabolites. Microbiol Res (2012) 1.57
Targeting mycobacterium protein tyrosine phosphatase B for antituberculosis agents. Proc Natl Acad Sci U S A (2010) 1.57
Advent of Imidazo[1,2-a]pyridine-3-carboxamides with Potent Multi- and Extended Drug Resistant Antituberculosis Activity. ACS Med Chem Lett (2011) 1.54
Preclinical efficacy spectrum and pharmacokinetics of ixabepilone. Cancer Chemother Pharmacol (2008) 1.53
Genetic variation of the bloom-forming Cyanobacterium Microcystis aeruginosa within and among lakes: implications for harmful algal blooms. Appl Environ Microbiol (2005) 1.48
Improved green fluorescent protein reporter gene-based microplate screening for antituberculosis compounds by utilizing an acetamidase promoter. Antimicrob Agents Chemother (2003) 1.46
Bromophycolides C-I from the Fijian red alga Callophycus serratus. J Nat Prod (2006) 1.43
New fish-killing alga in coastal Delaware produces neurotoxins. Environ Health Perspect (2002) 1.42
Community and ecosystem level consequences of chemical cues in the plankton. J Chem Ecol (2002) 1.41
Design, synthesis, and pharmacological evaluation of mefloquine-based ligands as novel antituberculosis agents. ChemMedChem (2007) 1.38
Impact of herbivore identity on algal succession and coral growth on a Caribbean reef. PLoS One (2010) 1.36
New perspectives on natural products in TB drug research. Life Sci (2005) 1.29
Callophycoic acids and callophycols from the Fijian red alga Callophycus serratus. J Org Chem (2007) 1.29
Herbivore preference for native vs. exotic plants: generalist herbivores from multiple continents prefer exotic plants that are evolutionarily naïve. PLoS One (2011) 1.28
A systematic approach to understand the mechanism of action of the bisthiazolium compound T4 on the human malaria parasite, Plasmodium falciparum. BMC Genomics (2008) 1.27
Manadomanzamines A and B: a novel alkaloid ring system with potent activity against mycobacteria and HIV-1. J Am Chem Soc (2003) 1.27
Manzamine B and E and ircinal A related alkaloids from an Indonesian Acanthostrongylophora sponge and their activity against infectious, tropical parasitic, and Alzheimer's diseases. J Nat Prod (2006) 1.25
Design, synthesis, and SAR studies of mefloquine-based ligands as potential antituberculosis agents. ChemMedChem (2006) 1.23
Synthesis, antimalarial and antitubercular activity of acetylenic chalcones. Bioorg Med Chem Lett (2009) 1.22
Effects of herbivory, nutrients, and reef protection on algal proliferation and coral growth on a tropical reef. Oecologia (2011) 1.22
Plasmodium falciparum: genome wide perturbations in transcript profiles among mixed stage cultures after chloroquine treatment. Exp Parasitol (2007) 1.21
Chemically mediated competition between microbes and animals: microbes as consumers in food webs. Ecology (2006) 1.20
Preclinical discovery of ixabepilone, a highly active antineoplastic agent. Cancer Chemother Pharmacol (2008) 1.19
Antimalarial bromophycolides J-Q from the Fijian red alga Callophycus serratus. J Org Chem (2009) 1.19
Discovery of aminothiazole inhibitors of cyclin-dependent kinase 2: synthesis, X-ray crystallographic analysis, and biological activities. J Med Chem (2002) 1.18
Polysome profiling reveals translational control of gene expression in the human malaria parasite Plasmodium falciparum. Genome Biol (2013) 1.18
Deciphering the ubiquitin-mediated pathway in apicomplexan parasites: a potential strategy to interfere with parasite virulence. PLoS One (2008) 1.18
Hapalindole-related alkaloids from the cultured cyanobacterium Fischerella ambigua. Phytochemistry (2010) 1.17
Mechanisms of gene regulation in Plasmodium. Am J Trop Med Hyg (2007) 1.15
Counter-current chromatography based analysis of synergy in an anti-tuberculosis ethnobotanical. J Chromatogr A (2007) 1.14
"Studies on biodiversity of Vietnam and Laos" 1998-2005: examining the impact. J Nat Prod (2006) 1.14
Seaweed allelopathy against coral: surface distribution of a seaweed secondary metabolite by imaging mass spectrometry. J Chem Ecol (2012) 1.09
Purity-activity relationships of natural products: the case of anti-TB active ursolic acid. J Nat Prod (2008) 1.07
Regulatory motifs uncovered among gene expression clusters in Plasmodium falciparum. Mol Biochem Parasitol (2007) 1.06
From serendipity to rational antituberculosis drug discovery of mefloquine-isoxazole carboxylic acid esters. J Med Chem (2009) 1.06
Synthesis and structure-activity relationships of varied ether linker analogues of the antitubercular drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5h-imidazo[2,1-b][1,3]oxazine (PA-824). J Med Chem (2011) 1.05
Synthesis and structure-activity studies of biphenyl analogues of the tuberculosis drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824). J Med Chem (2010) 1.04
Generation and exploration of new classes of antitubercular agents: The optimization of oxazolines, oxazoles, thiazolines, thiazoles to imidazo[1,2-a]pyridines and isomeric 5,6-fused scaffolds. Bioorg Med Chem (2012) 1.03
Synergistic antitumor activity of ixabepilone (BMS-247550) plus bevacizumab in multiple in vivo tumor models. Clin Cancer Res (2008) 1.02
Predator release of the gastropod Cyphoma gibbosum increases predation on gorgonian corals. Oecologia (2007) 1.02
Reactive desorption electrospray ionization mass spectrometry (DESI-MS) of natural products of a marine alga. Anal Bioanal Chem (2009) 1.02
Discovery of selective menaquinone biosynthesis inhibitors against Mycobacterium tuberculosis. J Med Chem (2012) 1.02
Competing phytoplankton undermines allelopathy of a bloom-forming dinoflagellate. Proc Biol Sci (2008) 1.01
Structural basis for catalysis of a tetrameric class IIa fructose 1,6-bisphosphate aldolase from Mycobacterium tuberculosis. J Mol Biol (2009) 1.01
Rational design of 5-phenyl-3-isoxazolecarboxylic acid ethyl esters as growth inhibitors of Mycobacterium tuberculosis. a potent and selective series for further drug development. J Med Chem (2010) 1.01
Identification and initial characterization of three novel cyclin-related proteins of the human malaria parasite Plasmodium falciparum. J Biol Chem (2003) 1.01
Enhancing hit identification in Mycobacterium tuberculosis drug discovery using validated dual-event Bayesian models. PLoS One (2013) 1.01
Cytotoxic flavone analogues of vitexicarpin, a constituent of the leaves of Vitex negundo. J Nat Prod (2003) 1.00
Prevalence of chemical defenses among freshwater plants. J Chem Ecol (2005) 0.99
Conservation of progesterone hormone function in invertebrate reproduction. Proc Natl Acad Sci U S A (2010) 0.99
BMS-536924 reverses IGF-IR-induced transformation of mammary epithelial cells and causes growth inhibition and polarization of MCF7 cells. Clin Cancer Res (2009) 0.97
Natural product leads for drug discovery: isolation, synthesis and biological evaluation of 6-cyano-5-methoxyindolo[2,3-a]carbazole based ligands as antibacterial agents. Bioorg Med Chem (2009) 0.97
A Plasmodium falciparum transcriptional cyclin-dependent kinase-related kinase with a crucial role in parasite proliferation associates with histone deacetylase activity. Eukaryot Cell (2010) 0.96
Geographic and genetic variation in feeding preference for chemically defended seaweeds. Evolution (2003) 0.96
Competition induces allelopathy but suppresses growth and anti-herbivore defence in a chemically rich seaweed. Proc Biol Sci (2014) 0.96