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Shinsan M Su
Author PubWeight™ 58.88
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Top papers
Rank
Title
Journal
Year
PubWeight™
‹?›
1
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate.
Nature
2009
19.65
2
The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate.
Cancer Cell
2010
13.13
3
Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations.
J Exp Med
2010
5.68
4
An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells.
Science
2013
5.10
5
IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics.
Nature
2012
4.04
6
Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation.
Science
2013
3.72
7
IDH mutations in glioma and acute myeloid leukemia.
Trends Mol Med
2010
2.83
8
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate.
Nature
2010
2.21
9
D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function.
Genes Dev
2012
2.10
10
Small molecule activation of PKM2 in cancer cells induces serine auxotrophy.
Chem Biol
2012
1.96
11
Non-invasive detection of 2-hydroxyglutarate and other metabolites in IDH1 mutant glioma patients using magnetic resonance spectroscopy.
J Neurooncol
2011
1.67