Shinsan M Su

Author PubWeight™ 58.88‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature 2009 19.65
2 The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate. Cancer Cell 2010 13.13
3 Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations. J Exp Med 2010 5.68
4 An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells. Science 2013 5.10
5 IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics. Nature 2012 4.04
6 Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation. Science 2013 3.72
7 IDH mutations in glioma and acute myeloid leukemia. Trends Mol Med 2010 2.83
8 Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature 2010 2.21
9 D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function. Genes Dev 2012 2.10
10 Small molecule activation of PKM2 in cancer cells induces serine auxotrophy. Chem Biol 2012 1.96
11 Non-invasive detection of 2-hydroxyglutarate and other metabolites in IDH1 mutant glioma patients using magnetic resonance spectroscopy. J Neurooncol 2011 1.67