Published in Int J Diabetes Dev Ctries on April 01, 2009
Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. Nat Genet (2009) 16.53
Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes. Science (2009) 16.35
Incidence trends for childhood type 1 diabetes in Europe during 1989-2003 and predicted new cases 2005-20: a multicentre prospective registration study. Lancet (2009) 10.02
GAD treatment and insulin secretion in recent-onset type 1 diabetes. N Engl J Med (2008) 5.74
Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice. Proc Natl Acad Sci U S A (1994) 3.77
CD3 antibody-induced dominant self tolerance in overtly diabetic NOD mice. J Immunol (1997) 2.89
The Environmental Determinants of Diabetes in the Young (TEDDY) Study. Ann N Y Acad Sci (2008) 2.65
B cell immunobiology in disease: evolving concepts from the clinic. Annu Rev Immunol (2006) 2.49
Rituximab: expanding role in therapy for lymphomas and autoimmune diseases. Annu Rev Med (2004) 1.66
Type 1 Diabetes TrialNet--an international collaborative clinical trials network. Ann N Y Acad Sci (2008) 1.44
The generation of a humanized, non-mitogenic CD3 monoclonal antibody which retains in vitro immunosuppressive properties. Eur J Immunol (1993) 1.44
B-cells promote intra-islet CD8+ cytotoxic T-cell survival to enhance type 1 diabetes. Diabetes (2008) 1.12
Approaches in type 1 diabetes research: A status report. Int J Diabetes Dev Ctries (2009) 1.08
B cells in autoimmune diabetes. Rev Diabet Stud (2005) 0.93
The effect of aglycosylation on the immunogenicity of a humanized therapeutic CD3 monoclonal antibody. Transplantation (1995) 0.87