1
|
N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial trafficking.
|
J Neurosci
|
2008
|
2.18
|
2
|
Expression of mutant huntingtin in mouse brain astrocytes causes age-dependent neurological symptoms.
|
Proc Natl Acad Sci U S A
|
2009
|
1.87
|
3
|
Proteasomal dysfunction in aging and Huntington disease.
|
Neurobiol Dis
|
2010
|
1.85
|
4
|
Accumulation of N-terminal mutant huntingtin in mouse and monkey models implicated as a pathogenic mechanism in Huntington's disease.
|
Hum Mol Genet
|
2008
|
1.70
|
5
|
Polyglutamine domain modulates the TBP-TFIIB interaction: implications for its normal function and neurodegeneration.
|
Nat Neurosci
|
2007
|
1.46
|
6
|
Differential activities of the ubiquitin-proteasome system in neurons versus glia may account for the preferential accumulation of misfolded proteins in neurons.
|
J Neurosci
|
2008
|
1.41
|
7
|
Expression of Huntington's disease protein results in apoptotic neurons in the brains of cloned transgenic pigs.
|
Hum Mol Genet
|
2010
|
1.33
|
8
|
Mutant huntingtin in glial cells exacerbates neurological symptoms of Huntington disease mice.
|
J Biol Chem
|
2010
|
1.25
|
9
|
Inhibiting the ubiquitin-proteasome system leads to preferential accumulation of toxic N-terminal mutant huntingtin fragments.
|
Hum Mol Genet
|
2010
|
1.08
|
10
|
Neuronal expression of TATA box-binding protein containing expanded polyglutamine in knock-in mice reduces chaperone protein response by impairing the function of nuclear factor-Y transcription factor.
|
Brain
|
2011
|
1.03
|
11
|
Polyglutamine expansion reduces the association of TATA-binding protein with DNA and induces DNA binding-independent neurotoxicity.
|
J Biol Chem
|
2008
|
0.98
|
12
|
Huntingtin-associated protein-1 interacts with pro-brain-derived neurotrophic factor and mediates its transport and release.
|
J Biol Chem
|
2009
|
0.96
|
13
|
Preferential accumulation of N-terminal mutant huntingtin in the nuclei of striatal neurons is regulated by phosphorylation.
|
Hum Mol Genet
|
2011
|
0.96
|
14
|
Neuronal Abelson helper integration site-1 (Ahi1) deficiency in mice alters TrkB signaling with a depressive phenotype.
|
Proc Natl Acad Sci U S A
|
2010
|
0.92
|
15
|
Sex-dependent effect of BAG1 in ameliorating motor deficits of Huntington disease transgenic mice.
|
J Biol Chem
|
2008
|
0.92
|
16
|
Differential ubiquitination and degradation of huntingtin fragments modulated by ubiquitin-protein ligase E3A.
|
Proc Natl Acad Sci U S A
|
2014
|
0.91
|
17
|
Impaired mitochondrial trafficking in Huntington's disease.
|
Biochim Biophys Acta
|
2009
|
0.91
|
18
|
Activation of gene transcription by heat shock protein 27 may contribute to its neuronal protection.
|
J Biol Chem
|
2009
|
0.90
|
19
|
Huntingtin-associated protein-1 deficiency in orexin-producing neurons impairs neuronal process extension and leads to abnormal behavior in mice.
|
J Biol Chem
|
2010
|
0.88
|
20
|
Synaptic mutant huntingtin inhibits synapsin-1 phosphorylation and causes neurological symptoms.
|
J Cell Biol
|
2013
|
0.86
|
21
|
Polyglutamine toxicity in non-neuronal cells.
|
Cell Res
|
2010
|
0.86
|
22
|
Nuclear accumulation of polyglutamine disease proteins and neuropathology.
|
Mol Brain
|
2009
|
0.85
|
23
|
Transcriptional dysregulation of TrkA associates with neurodegeneration in spinocerebellar ataxia type 17.
|
Hum Mol Genet
|
2009
|
0.85
|
24
|
14-3-3 protein interacts with Huntingtin-associated protein 1 and regulates its trafficking.
|
J Biol Chem
|
2006
|
0.85
|
25
|
Impaired alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor trafficking and function by mutant huntingtin.
|
J Biol Chem
|
2011
|
0.84
|
26
|
Loss of Ahi1 affects early development by impairing BM88/Cend1-mediated neuronal differentiation.
|
J Neurosci
|
2013
|
0.82
|
27
|
Influence of species differences on the neuropathology of transgenic Huntington's disease animal models.
|
J Genet Genomics
|
2012
|
0.82
|
28
|
Interacting proteins as genetic modifiers of Huntington disease.
|
Trends Genet
|
2007
|
0.81
|
29
|
Clearance of mutant huntingtin.
|
Autophagy
|
2010
|
0.79
|
30
|
Large Animal Models of Huntington's Disease.
|
Curr Top Behav Neurosci
|
2015
|
0.79
|
31
|
Biomineralization-based virus shell-engineering: towards neutralization escape and tropism expansion.
|
Adv Healthc Mater
|
2012
|
0.79
|
32
|
Loss of huntingtin-associated protein 1 impairs insulin secretion from pancreatic β-cells.
|
Cell Mol Life Sci
|
2011
|
0.79
|
33
|
Hypothalamic Ahi1 mediates feeding behavior through interaction with 5-HT2C receptor.
|
J Biol Chem
|
2011
|
0.79
|
34
|
Zika Virus Causes Testis Damage and Leads to Male Infertility in Mice.
|
Cell
|
2017
|
0.77
|
35
|
Lack of interleukin-1 type 1 receptor enhances the accumulation of mutant huntingtin in the striatum and exacerbates the neurological phenotypes of Huntington's disease mice.
|
Mol Brain
|
2010
|
0.76
|
36
|
TDP-43 causes differential pathology in neuronal versus glial cells in the mouse brain.
|
Hum Mol Genet
|
2013
|
0.76
|
37
|
Robust control of nonlinear MAGLEV suspension system with mismatched uncertainties via DOBC approach.
|
ISA Trans
|
2011
|
0.75
|
38
|
p53 protein activates the transcription of human proliferating cell nuclear antigen in response to 4-nitroquinoline N-oxide treatment.
|
Int J Biochem Cell Biol
|
2005
|
0.75
|
39
|
Preparation of phenylboronic acid-silica hybrid monolithic column with one-pot approach for capillary liquid chromatography of biomolecules.
|
J Chromatogr A
|
2012
|
0.75
|
40
|
Synergistic application of geometric and radiometric features of LiDAR data for urban land cover mapping.
|
Opt Express
|
2015
|
0.75
|
41
|
Distributed finite-time containment control for double-integrator multiagent systems.
|
IEEE Trans Cybern
|
2014
|
0.75
|
42
|
Composite Backstepping Consensus Algorithms of Leader-Follower Higher-Order Nonlinear Multiagent Systems Subject to Mismatched Disturbances.
|
IEEE Trans Cybern
|
2017
|
0.75
|
43
|
Control-oriented modeling and real-time control for the ozone dosing process of drinking water treatment.
|
Environ Sci Technol
|
2013
|
0.75
|