Shihua Li

Author PubWeight™ 35.99‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial trafficking. J Neurosci 2008 2.18
2 Expression of mutant huntingtin in mouse brain astrocytes causes age-dependent neurological symptoms. Proc Natl Acad Sci U S A 2009 1.87
3 Proteasomal dysfunction in aging and Huntington disease. Neurobiol Dis 2010 1.85
4 Accumulation of N-terminal mutant huntingtin in mouse and monkey models implicated as a pathogenic mechanism in Huntington's disease. Hum Mol Genet 2008 1.70
5 Polyglutamine domain modulates the TBP-TFIIB interaction: implications for its normal function and neurodegeneration. Nat Neurosci 2007 1.46
6 Differential activities of the ubiquitin-proteasome system in neurons versus glia may account for the preferential accumulation of misfolded proteins in neurons. J Neurosci 2008 1.41
7 Expression of Huntington's disease protein results in apoptotic neurons in the brains of cloned transgenic pigs. Hum Mol Genet 2010 1.33
8 Mutant huntingtin in glial cells exacerbates neurological symptoms of Huntington disease mice. J Biol Chem 2010 1.25
9 Inhibiting the ubiquitin-proteasome system leads to preferential accumulation of toxic N-terminal mutant huntingtin fragments. Hum Mol Genet 2010 1.08
10 Neuronal expression of TATA box-binding protein containing expanded polyglutamine in knock-in mice reduces chaperone protein response by impairing the function of nuclear factor-Y transcription factor. Brain 2011 1.03
11 Polyglutamine expansion reduces the association of TATA-binding protein with DNA and induces DNA binding-independent neurotoxicity. J Biol Chem 2008 0.98
12 Huntingtin-associated protein-1 interacts with pro-brain-derived neurotrophic factor and mediates its transport and release. J Biol Chem 2009 0.96
13 Preferential accumulation of N-terminal mutant huntingtin in the nuclei of striatal neurons is regulated by phosphorylation. Hum Mol Genet 2011 0.96
14 Neuronal Abelson helper integration site-1 (Ahi1) deficiency in mice alters TrkB signaling with a depressive phenotype. Proc Natl Acad Sci U S A 2010 0.92
15 Sex-dependent effect of BAG1 in ameliorating motor deficits of Huntington disease transgenic mice. J Biol Chem 2008 0.92
16 Differential ubiquitination and degradation of huntingtin fragments modulated by ubiquitin-protein ligase E3A. Proc Natl Acad Sci U S A 2014 0.91
17 Impaired mitochondrial trafficking in Huntington's disease. Biochim Biophys Acta 2009 0.91
18 Activation of gene transcription by heat shock protein 27 may contribute to its neuronal protection. J Biol Chem 2009 0.90
19 Huntingtin-associated protein-1 deficiency in orexin-producing neurons impairs neuronal process extension and leads to abnormal behavior in mice. J Biol Chem 2010 0.88
20 Synaptic mutant huntingtin inhibits synapsin-1 phosphorylation and causes neurological symptoms. J Cell Biol 2013 0.86
21 Polyglutamine toxicity in non-neuronal cells. Cell Res 2010 0.86
22 Nuclear accumulation of polyglutamine disease proteins and neuropathology. Mol Brain 2009 0.85
23 Transcriptional dysregulation of TrkA associates with neurodegeneration in spinocerebellar ataxia type 17. Hum Mol Genet 2009 0.85
24 14-3-3 protein interacts with Huntingtin-associated protein 1 and regulates its trafficking. J Biol Chem 2006 0.85
25 Impaired alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor trafficking and function by mutant huntingtin. J Biol Chem 2011 0.84
26 Loss of Ahi1 affects early development by impairing BM88/Cend1-mediated neuronal differentiation. J Neurosci 2013 0.82
27 Influence of species differences on the neuropathology of transgenic Huntington's disease animal models. J Genet Genomics 2012 0.82
28 Interacting proteins as genetic modifiers of Huntington disease. Trends Genet 2007 0.81
29 Clearance of mutant huntingtin. Autophagy 2010 0.79
30 Large Animal Models of Huntington's Disease. Curr Top Behav Neurosci 2015 0.79
31 Biomineralization-based virus shell-engineering: towards neutralization escape and tropism expansion. Adv Healthc Mater 2012 0.79
32 Loss of huntingtin-associated protein 1 impairs insulin secretion from pancreatic β-cells. Cell Mol Life Sci 2011 0.79
33 Hypothalamic Ahi1 mediates feeding behavior through interaction with 5-HT2C receptor. J Biol Chem 2011 0.79
34 Zika Virus Causes Testis Damage and Leads to Male Infertility in Mice. Cell 2017 0.77
35 Lack of interleukin-1 type 1 receptor enhances the accumulation of mutant huntingtin in the striatum and exacerbates the neurological phenotypes of Huntington's disease mice. Mol Brain 2010 0.76
36 TDP-43 causes differential pathology in neuronal versus glial cells in the mouse brain. Hum Mol Genet 2013 0.76
37 Robust control of nonlinear MAGLEV suspension system with mismatched uncertainties via DOBC approach. ISA Trans 2011 0.75
38 p53 protein activates the transcription of human proliferating cell nuclear antigen in response to 4-nitroquinoline N-oxide treatment. Int J Biochem Cell Biol 2005 0.75
39 Preparation of phenylboronic acid-silica hybrid monolithic column with one-pot approach for capillary liquid chromatography of biomolecules. J Chromatogr A 2012 0.75
40 Synergistic application of geometric and radiometric features of LiDAR data for urban land cover mapping. Opt Express 2015 0.75
41 Distributed finite-time containment control for double-integrator multiagent systems. IEEE Trans Cybern 2014 0.75
42 Composite Backstepping Consensus Algorithms of Leader-Follower Higher-Order Nonlinear Multiagent Systems Subject to Mismatched Disturbances. IEEE Trans Cybern 2017 0.75
43 Control-oriented modeling and real-time control for the ozone dosing process of drinking water treatment. Environ Sci Technol 2013 0.75