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1
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Ventricular septal defect and cardiomyopathy in mice lacking the transcription factor CHF1/Hey2.
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Proc Natl Acad Sci U S A
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2002
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2.04
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2
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Essential role for miR-196a in brown adipogenesis of white fat progenitor cells.
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PLoS Biol
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2012
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1.53
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3
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Angiotensin II accelerates osteoporosis by activating osteoclasts.
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FASEB J
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2008
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1.42
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4
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NF-kappaB is a key mediator of cerebral aneurysm formation.
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Circulation
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2007
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1.39
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5
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Role of angiotensin II-regulated apoptosis through distinct AT1 and AT2 receptors in neointimal formation.
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Circulation
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2002
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1.35
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6
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Estrogen inhibits vascular calcification via vascular RANKL system: common mechanism of osteoporosis and vascular calcification.
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Circ Res
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2010
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1.17
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7
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Transfection of human hepatocyte growth factor gene ameliorates secondary lymphedema via promotion of lymphangiogenesis.
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Circulation
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2006
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1.13
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8
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ACE inhibitor improves insulin resistance in diabetic mouse via bradykinin and NO.
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Hypertension
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2002
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1.13
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9
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Transcription factor CHF1/Hey2 suppresses cardiac hypertrophy through an inhibitory interaction with GATA4.
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Am J Physiol Heart Circ Physiol
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2006
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1.10
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10
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Ubiquitin carboxyl-terminal hydrolase L1, a novel deubiquitinating enzyme in the vasculature, attenuates NF-kappaB activation.
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Arterioscler Thromb Vasc Biol
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2007
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1.07
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11
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Zyxin mediates actin fiber reorganization in epithelial-mesenchymal transition and contributes to endocardial morphogenesis.
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Mol Biol Cell
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2009
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1.04
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12
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Magnetic nanoparticles with surface modification enhanced gene delivery of HVJ-E vector.
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Biochem Biophys Res Commun
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2005
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0.98
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13
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Priming with angiopoietin-1 augments the vasculogenic potential of the peripheral blood stem cells mobilized with granulocyte colony-stimulating factor through a novel Tie2/Ets-1 pathway.
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Circulation
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2009
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0.97
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14
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Lymphedema and therapeutic lymphangiogenesis.
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Biomed Res Int
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2013
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0.97
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15
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Moderate to high concentrations of high-density lipoprotein from healthy subjects paradoxically impair human endothelial progenitor cells and related angiogenesis by activating Rho-associated kinase pathways.
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Arterioscler Thromb Vasc Biol
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2012
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0.94
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16
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Cross-talk of receptor activator of nuclear factor-κB ligand signaling with renin-angiotensin system in vascular calcification.
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Arterioscler Thromb Vasc Biol
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2013
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0.94
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17
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Pitavastatin suppresses formation and progression of cerebral aneurysms through inhibition of the nuclear factor kappaB pathway.
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Neurosurgery
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2009
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0.93
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18
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Dipeptidyl peptidase-4 inhibitor improves neovascularization by increasing circulating endothelial progenitor cells.
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Br J Pharmacol
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2012
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0.93
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19
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The transcription factors Tbx18 and Wt1 control the epicardial epithelial-mesenchymal transition through bi-directional regulation of Slug in murine primary epicardial cells.
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PLoS One
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2013
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0.93
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20
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Prevention of osteoporosis by angiotensin-converting enzyme inhibitor in spontaneous hypertensive rats.
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Hypertens Res
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2009
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0.92
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21
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Fluvastatin enhances the inhibitory effects of a selective angiotensin II type 1 receptor blocker, valsartan, on vascular neointimal formation.
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Circulation
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2003
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0.91
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22
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Effect of an antimicrobial agent on atherosclerotic plaques: assessment of metalloproteinase activity by molecular imaging.
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J Am Coll Cardiol
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2010
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0.90
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23
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Effect of angiotensin II type 1 receptor blockade on cardiac remodeling in angiotensin II type 2 receptor null mice.
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Arterioscler Thromb Vasc Biol
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2002
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0.89
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24
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Increase in nuclease resistance and incorporation of NF-kappaB decoy oligodeoxynucleotides by modification of the 3'-terminus.
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J Gene Med
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2007
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0.88
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25
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Modification of decoy oligodeoxynucleotides to achieve the stability and therapeutic efficacy.
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Curr Top Med Chem
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2012
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0.88
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26
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FHL-2 suppresses VEGF-induced phosphatidylinositol 3-kinase/Akt activation via interaction with sphingosine kinase-1.
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Arterioscler Thromb Vasc Biol
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2009
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0.88
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27
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New treatment of periodontal diseases by using NF-kappaB decoy oligodeoxynucleotides via prevention of bone resorption and promotion of wound healing.
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Antioxid Redox Signal
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2009
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0.88
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28
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Angiotensin II subtype 2 receptor activation inhibits insulin-induced phosphoinositide 3-kinase and Akt and induces apoptosis in PC12W cells.
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Mol Endocrinol
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2002
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0.88
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29
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Gene therapy and cell-based therapies for therapeutic angiogenesis in peripheral artery disease.
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Biomed Res Int
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2013
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0.87
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30
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Variation in OSBPL10 is associated with dyslipidemia.
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Hypertens Res
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2010
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0.86
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31
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Potential role of CYLD (Cylindromatosis) as a deubiquitinating enzyme in vascular cells.
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Am J Pathol
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2008
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0.85
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32
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Estrogen activates phosphatases and antagonizes growth-promoting effect of angiotensin II.
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Hypertension
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2002
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0.85
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33
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Teneligliptin : expectations for its pleiotropic action.
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Expert Opin Pharmacother
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2015
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0.85
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34
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Development of a novel antimicrobial peptide, AG-30, with angiogenic properties.
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J Cell Mol Med
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2008
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0.84
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35
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Alpha-synuclein elicits glucose uptake and utilization in adipocytes through the Gab1/PI3K/Akt transduction pathway.
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Cell Mol Life Sci
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2012
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0.83
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36
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Identification of evidence suggestive of an association with peripheral arterial disease at the OSBPL10 locus by genome-wide investigation in the Japanese population.
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J Atheroscler Thromb
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2010
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0.83
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37
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Therapeutic vaccine against DPP4 improves glucose metabolism in mice.
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Proc Natl Acad Sci U S A
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2014
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0.82
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38
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Systemic administration of ribbon-type decoy oligodeoxynucleotide against nuclear factor κB and ets prevents abdominal aortic aneurysm in rat model.
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Mol Ther
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2010
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0.82
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39
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Critical roles of cold shock domain protein A as an endogenous angiogenesis inhibitor in skeletal muscle.
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Antioxid Redox Signal
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2011
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0.81
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40
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Hypoxia-induced renal epithelial cell death through caspase-dependent pathway: role of Bcl-2, Bcl-xL and Bax in tubular injury.
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Int J Mol Med
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2004
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0.81
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41
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HIG1, a novel regulator of mitochondrial γ-secretase, maintains normal mitochondrial function.
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FASEB J
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2012
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0.81
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42
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Irbesartan improves endothelial dysfunction, abnormal lipid profile, proteinuria and liver dysfunction in Zucker diabetic fatty rats independent of glucose and insulin levels.
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Exp Ther Med
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2011
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0.80
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43
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Inorganic polyphosphate differentiates human mesenchymal stem cells into osteoblastic cells.
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J Bone Miner Metab
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2010
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0.80
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44
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Role of central nervous system periostin in cerebral ischemia.
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Stroke
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2012
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0.80
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45
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Gene therapy for peripheral arterial disease.
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Expert Opin Biol Ther
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2014
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0.80
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46
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Decrease in blood pressure and regression of cardiovascular complications by angiotensin II vaccine in mice.
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PLoS One
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2013
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0.80
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47
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Therapeutic effect of ribbon-type nuclear factor-κB decoy oligonucleotides in a rat model of inflammatory bowel disease.
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Curr Gene Ther
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2012
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0.80
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48
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Estrogen attenuates vascular remodeling in Lp(a) transgenic mice.
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Atherosclerosis
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2010
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0.79
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49
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Unique remodeling processes after vascular injury in intracranial arteries: analysis using a novel mouse model.
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J Cereb Blood Flow Metab
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2013
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0.79
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50
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Cold shock domain protein A (CSDA) overexpression inhibits tumor growth and lymph node metastasis in a mouse model of squamous cell carcinoma.
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Clin Exp Metastasis
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2010
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0.78
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51
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Development of high-throughput functional screening of therapeutic genes, using a hemagglutinating virus of Japan envelope vector.
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Hum Gene Ther
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2006
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0.77
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52
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Development of nucleic acid drugs for neurological disorders.
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Curr Top Med Chem
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2012
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0.77
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53
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Fluvastatin improves osteoporosis in fructose-fed insulin resistant model rats through blockade of the classical mevalonate pathway and antioxidant action.
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Int J Mol Med
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2009
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0.77
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54
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Cilnidipine, but not amlodipine, ameliorates osteoporosis in ovariectomized hypertensive rats through inhibition of the N-type calcium channel.
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Hypertens Res
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2011
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0.77
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55
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Involvement of gamma-secretase in postnatal angiogenesis.
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Biochem Biophys Res Commun
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2007
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56
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Development of novel DNA vaccine for VEGF in murine cancer model.
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Sci Rep
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2013
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57
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Inhibition of neointima formation through DNA vaccination for apolipoprotein(a): a new therapeutic strategy for lipoprotein(a).
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Sci Rep
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2013
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0.75
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58
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Do angiotensin receptor blockers protect against Alzheimer's disease?
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Drugs Aging
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2013
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0.75
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59
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No influence of tumor growth by intramuscular injection of hepatocyte growth factor plasmid DNA: safety evaluation of therapeutic angiogenesis gene therapy in mice.
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Biochem Biophys Res Commun
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2004
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0.75
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60
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[Activation of osteoclasts by RAAS and strategy of target therapy on bone metabolic diseases].
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Nihon Rinsho
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2012
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61
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A novel lipoprotein (a) lowering drug, D-47, decreases neointima thickening after vascular injury.
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J Med Invest
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2017
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Novel drug delivery system by surface modified magnetic nanoparticles.
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J Nanosci Nanotechnol
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2006
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0.75
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63
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N141I mutant presenilin-2 gene enhances neuronal cell death and decreases bcl-2 expression.
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Life Sci
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2002
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0.75
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64
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[Bone metabolism and cardiovascular function update. Cross link of hypertension, bone loss and vascular calcification - common back grounds in renin angiotensin system with anti-aging aspect -].
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Clin Calcium
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2014
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0.75
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65
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Nucleic acid drugs for preventing restenosis after coronary revascularization.
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Curr Top Med Chem
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2012
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66
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[Common molecular mechanism of osteoporosis and vascular diseases].
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Nihon Ronen Igakkai Zasshi
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2011
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0.75
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