PubRank

Eugenio Santos

Author PubWeight™ 39.39‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Ras in cancer and developmental diseases. Genes Cancer 2011 2.68
2 A genome-wide association study for myopia and refractive error identifies a susceptibility locus at 15q25. Nat Genet 2010 2.10
3 Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption. Proc Natl Acad Sci U S A 2011 2.01
4 Endogenous expression of Hras(G12V) induces developmental defects and neoplasms with copy number imbalances of the oncogene. Proc Natl Acad Sci U S A 2009 1.67
5 Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival. EMBO J 2010 1.66
6 Distinct utilization of effectors and biological outcomes resulting from site-specific Ras activation: Ras functions in lipid rafts and Golgi complex are dispensable for proliferation and transformation. Mol Cell Biol 2006 1.46
7 Functional specificity of ras isoforms: so similar but so different. Genes Cancer 2011 1.30
8 The RasGrf family of mammalian guanine nucleotide exchange factors. Biochim Biophys Acta 2010 1.22
9 Ras-GRF1 signaling is required for normal beta-cell development and glucose homeostasis. EMBO J 2003 1.21
10 RasGrf1 deficiency delays aging in mice. Aging (Albany NY) 2011 1.16
11 RasGRF1 disruption causes retinal photoreception defects and associated transcriptomic alterations. J Neurochem 2009 1.12
12 RasGRF2, a guanosine nucleotide exchange factor for Ras GTPases, participates in T-cell signaling responses. Mol Cell Biol 2007 1.07
13 RASGRF2 regulates alcohol-induced reinforcement by influencing mesolimbic dopamine neuron activity and dopamine release. Proc Natl Acad Sci U S A 2012 1.06
14 Mammalian son of sevenless Guanine nucleotide exchange factors: old concepts and new perspectives. Genes Cancer 2011 1.04
15 Targeted disruption of Ras-Grf2 shows its dispensability for mouse growth and development. Mol Cell Biol 2002 1.03
16 Diversity of genomic breakpoints in TFG-ALK translocations in anaplastic large cell lymphomas: identification of a new TFG-ALK(XL) chimeric gene with transforming activity. Am J Pathol 2002 0.99
17 Deletion of H-Ras decreases renal fibrosis and myofibroblast activation following ureteral obstruction in mice. Kidney Int 2009 0.97
18 Involvement of H- and N-Ras isoforms in transforming growth factor-beta1-induced proliferation and in collagen and fibronectin synthesis. Exp Cell Res 2006 0.90
19 H-ras and N-ras are dispensable for T-cell development and activation but critical for protective Th1 immunity. Blood 2011 0.89
20 H-Ras isoform modulates extracellular matrix synthesis, proliferation, and migration in fibroblasts. Am J Physiol Cell Physiol 2011 0.87
21 The use of knockout mice reveals a synergistic role of the Vav1 and Rasgrf2 gene deficiencies in lymphomagenesis and metastasis. PLoS One 2009 0.86
22 N-ras couples antigen receptor signaling to Eomesodermin and to functional CD8+ T cell memory but not to effector differentiation. J Exp Med 2013 0.85
23 Characterization of p87C3G, a novel, truncated C3G isoform that is overexpressed in chronic myeloid leukemia and interacts with Bcr-Abl. Exp Cell Res 2006 0.84
24 C3G-mediated suppression of oncogene-induced focus formation in fibroblasts involves inhibition of ERK activation, cyclin A expression and alterations of anchorage-independent growth. Oncogene 2004 0.83
25 Serum-dependent transcriptional networks identify distinct functional roles for H-Ras and N-Ras during initial stages of the cell cycle. Genome Biol 2009 0.83
26 C3G mediated suppression of malignant transformation involves activation of PP2A phosphatases at the subcortical actin cytoskeleton. Exp Cell Res 2007 0.83
27 The Ras-like protein R-Ras2/TC21 is important for proper mammary gland development. Mol Biol Cell 2012 0.81
28 Targeted genomic disruption of h-ras induces hypotension through a NO-cGMP-PKG pathway-dependent mechanism. Hypertension 2010 0.80
29 The small GTPase N-Ras regulates extracellular matrix synthesis, proliferation and migration in fibroblasts. Biochim Biophys Acta 2013 0.78
30 Rasgrf2 controls noradrenergic involvement in the acute and subchronic effects of alcohol in the brain. Psychopharmacology (Berl) 2014 0.78
31 Functional redundancy of Sos1 and Sos2 for lymphopoiesis and organismal homeostasis and survival. Mol Cell Biol 2013 0.78
32 Analysis of k-ras nuclear expression in fibroblasts and mesangial cells. PLoS One 2010 0.78
33 Overexpression of RasN17 fails to neutralize endogenous Ras in MCF7 breast cancer cells. J Biochem 2005 0.77
34 Activation of small GTPase Ras and renal fibrosis. J Nephrol 2005 0.77
35 Targeted genomic disruption of H-ras and N-ras has no effect on early renal changes after unilateral ureteral ligation. World J Urol 2009 0.77
36 Differential involvement of H- and K-Ras in Raf-1 activation determines the role of calmodulin in MAPK signaling. Cell Signal 2009 0.77
37 Transcriptional profiling reveals functional links between RasGrf1 and Pttg1 in pancreatic beta cells. BMC Genomics 2014 0.76
38 Monographs editor. Genes Cancer 2011 0.75