Unravelling the molecular basis of the selectivity of the HIV-1 fusion inhibitor sifuvirtide towards phosphatidylcholine-rich rigid membranes.

PubWeight™: 0.78‹?›

🔗 View Article (PMID 20153294)

Published in Biochim Biophys Acta on February 11, 2010

Authors

Henri G Franquelim1, A Salomé Veiga, G Weissmüller, Nuno C Santos, Miguel A R B Castanho

Author Affiliations

1: Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, 1649-028 Lisboa, Portugal.

Articles by these authors

Enhanced lithium depletion in Sun-like stars with orbiting planets. Nature (2009) 2.25

Cell-penetrating peptides and antimicrobial peptides: how different are they? Biochem J (2006) 1.92

Antimicrobial peptides: linking partition, activity and high membrane-bound concentrations. Nat Rev Microbiol (2009) 1.79

An extrasolar planetary system with three Neptune-mass planets. Nature (2006) 1.73

From antimicrobial to anticancer peptides. A review. Front Microbiol (2013) 1.56

Quantifying molecular partition into model systems of biomembranes: an emphasis on optical spectroscopic methods. Biochim Biophys Acta (2003) 1.32

Escherichia coli cell surface perturbation and disruption induced by antimicrobial peptides BP100 and pepR. J Biol Chem (2010) 1.27

Evaluation of lipopolysaccharide aggregation by light scattering spectroscopy. Chembiochem (2003) 1.11

Translocation of beta-galactosidase mediated by the cell-penetrating peptide pep-1 into lipid vesicles and human HeLa cells is driven by membrane electrostatic potential. Biochemistry (2005) 1.10

An overview of the biophysical applications of atomic force microscopy. Biophys Chem (2004) 1.07

Atomic force microscopy-based molecular recognition of a fibrinogen receptor on human erythrocytes. ACS Nano (2010) 1.06

Decoding the membrane activity of the cyclotide kalata B1: the importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities. J Biol Chem (2011) 1.06

rBPI(21) promotes lipopolysaccharide aggregation and exerts its antimicrobial effects by (hemi)fusion of PG-containing membranes. PLoS One (2009) 1.06

A mechanistic paradigm for broad-spectrum antivirals that target virus-cell fusion. PLoS Pathog (2013) 1.05

What can light scattering spectroscopy do for membrane-active peptide studies? J Pept Sci (2008) 1.05

Design and characterization of novel antimicrobial peptides, R-BP100 and RW-BP100, with activity against Gram-negative and Gram-positive bacteria. Biochim Biophys Acta (2012) 1.04

Dengue virus capsid protein binding to hepatic lipid droplets (LD) is potassium ion dependent and is mediated by LD surface proteins. J Virol (2011) 1.04

Extracellular alpha-synuclein oligomers modulate synaptic transmission and impair LTP via NMDA-receptor activation. J Neurosci (2012) 1.01

Omiganan interaction with bacterial membranes and cell wall models. Assigning a biological role to saturation. Biochim Biophys Acta (2007) 0.97

HIV fusion inhibitor peptide T-1249 is able to insert or adsorb to lipidic bilayers. Putative correlation with improved efficiency. J Am Chem Soc (2004) 0.95

PrP(106-126) does not interact with membranes under physiological conditions. Biophys J (2008) 0.95

Quantitative imaging of endosome acidification and single retrovirus fusion with distinct pools of early endosomes. Proc Natl Acad Sci U S A (2012) 0.95

Putative role of membranes in the HIV fusion inhibitor enfuvirtide mode of action at the molecular level. Biochem J (2004) 0.94

Phosphatidylethanolamine binding is a conserved feature of cyclotide-membrane interactions. J Biol Chem (2012) 0.92

The disordered N-terminal region of dengue virus capsid protein contains a lipid-droplet-binding motif. Biochem J (2012) 0.92

Arginine-rich self-assembling peptides as potent antibacterial gels. Biomaterials (2012) 0.92

Interactions of HIV-1 antibodies 2F5 and 4E10 with a gp41 epitope prebound to host and viral membrane model systems. Chembiochem (2009) 0.92

How to address CPP and AMP translocation? Methods to detect and quantify peptide internalization in vitro and in vivo (Review). Mol Membr Biol (2007) 0.90

Study of nanomechanical properties of human hair shaft in a case of pili annulati by atomic force microscopy. J Eur Acad Dermatol Venereol (2007) 0.90

Quantitative assessment of peptide-lipid interactions. Ubiquitous fluorescence methodologies. Biochim Biophys Acta (2010) 0.90

Re-evaluating the role of strongly charged sequences in amphipathic cell-penetrating peptides: a fluorescence study using Pep-1. FEBS Lett (2005) 0.89

Atomic force microscopy study of tooth surfaces. J Struct Biol (1999) 0.89

Anionic lipids are required for vesicular stomatitis virus G protein-mediated single particle fusion with supported lipid bilayers. J Biol Chem (2013) 0.88

Sifuvirtide screens rigid membrane surfaces. establishment of a correlation between efficacy and membrane domain selectivity among HIV fusion inhibitor peptides. J Am Chem Soc (2008) 0.88

Conjugation of cholesterol to HIV-1 fusion inhibitor C34 increases peptide-membrane interactions potentiating its action. PLoS One (2013) 0.88

Biophysical characterization of polymyxin B interaction with LPS aggregates and membrane model systems. Biopolymers (2012) 0.88

HIV-1 fusion inhibitor peptides enfuvirtide and T-1249 interact with erythrocyte and lymphocyte membranes. PLoS One (2010) 0.87

Atomic force microscopy-based force spectroscopy--biological and biomedical applications. IUBMB Life (2012) 0.87

Variations on fibrinogen-erythrocyte interactions during cell aging. PLoS One (2011) 0.87

Omiganan pentahydrochloride in the front line of clinical applications of antimicrobial peptides. Recent Pat Antiinfect Drug Discov (2006) 0.87

Cell-penetrating peptides: A tool for effective delivery in gene-targeted therapies. IUBMB Life (2014) 0.87

Energy-independent translocation of cell-penetrating peptides occurs without formation of pores. A biophysical study with pep-1. Mol Membr Biol (2007) 0.86

Interaction between dengue virus fusion peptide and lipid bilayers depends on peptide clustering. Mol Membr Biol (2008) 0.86

Conformational and orientational guidance of the analgesic dipeptide kyotorphin induced by lipidic membranes: putative correlation toward receptor docking. J Phys Chem B (2006) 0.86

Prediction of antibacterial activity from physicochemical properties of antimicrobial peptides. PLoS One (2011) 0.86

Fluorescence spectroscopy evaluation of fibrinogen-beta-estradiol binding. J Photochem Photobiol B (2006) 0.86

Anti-HIV-1 antibodies 2F5 and 4E10 interact differently with lipids to bind their epitopes. AIDS (2011) 0.85

Using zeta-potential measurements to quantify peptide partition to lipid membranes. Eur Biophys J (2011) 0.85

Interaction of the Dengue virus fusion peptide with membranes assessed by NMR: The essential role of the envelope protein Trp101 for membrane fusion. J Mol Biol (2009) 0.85

Translocation or membrane disintegration? Implication of peptide-membrane interactions in pep-1 activity. J Pept Sci (2008) 0.85

Isoelectric point determination for Glossoscolex paulistus extracellular hemoglobin: oligomeric stability in acidic pH and relevance to protein-surfactant interactions. Langmuir (2010) 0.84

Shiga toxin B-subunit sequential binding to its natural receptor in lipid membranes. Biochim Biophys Acta (2006) 0.84

The antimicrobial activity of Sub3 is dependent on membrane binding and cell-penetrating ability. Chembiochem (2013) 0.83

Molecular characterization of the interaction of crotamine-derived nucleolar targeting peptides with lipid membranes. Biochim Biophys Acta (2012) 0.83

Fold-unfold transitions in the selectivity and mechanism of action of the N-terminal fragment of the bactericidal/permeability-increasing protein (rBPI(21)). Biophys J (2009) 0.83

Drug-lipid interaction evaluation: why a 19th century solution? Trends Pharmacol Sci (2010) 0.82

Environmental factors that enhance the action of the cell penetrating peptide pep-1 A spectroscopic study using lipidic vesicles. Biochim Biophys Acta (2005) 0.82

Filipin orientation revealed by linear dichroism. Implication for a model of action. J Am Chem Soc (2004) 0.82

Dynamic light scattering and optical absorption spectroscopy study of pH and temperature stabilities of the extracellular hemoglobin of Glossoscolex paulistus. Biophys J (2007) 0.82

Complexation and full characterization of the tretinoin and dimethyl-β-cyclodextrin complex. AAPS PharmSciTech (2011) 0.82

Interaction of peptides with biomembranes assessed by potential-sensitive fluorescent probes. J Pept Sci (2008) 0.82

Anticancer peptide SVS-1: efficacy precedes membrane neutralization. Biochemistry (2012) 0.82

Evaluation of the membrane lipid selectivity of the pea defensin Psd1. Biochim Biophys Acta (2012) 0.81

The toxicity of prion protein fragment PrP(106-126) is not mediated by membrane permeabilization as shown by a M112W substitution. Biochemistry (2009) 0.81

Nucleic acid delivery by cell penetrating peptides derived from dengue virus capsid protein: design and mechanism of action. FEBS J (2013) 0.81

Decoding distinct membrane interactions of HIV-1 fusion inhibitors using a combined atomic force and fluorescence microscopy approach. Biochim Biophys Acta (2013) 0.80

The Mechanism of Action of Antimicrobial Peptides: Lipid Vesicles vs. Bacteria. Front Immunol (2012) 0.80

Why are HIV-1 fusion inhibitors not effective against SARS-CoV? Biophysical evaluation of molecular interactions. Biochim Biophys Acta (2005) 0.80

The rigid amphipathic fusion inhibitor dUY11 acts through photosensitization of viruses. J Virol (2013) 0.80

Fibrinogen-beta-estradiol binding studied by fluorescence spectroscopy: denaturation and pH effects. J Fluoresc (2006) 0.80

Fast membrane association is a crucial factor in the peptide pep-1 translocation mechanism: a kinetic study followed by surface plasmon resonance. Biopolymers (2010) 0.80

Conjugated linoleic acid reduces permeability and fluidity of adipose plasma membranes from obese Zucker rats. Biochem Biophys Res Commun (2010) 0.79

Infection by Plasmodium changes shape and stiffness of hepatic cells. Nanomedicine (2011) 0.79

Translocating the blood-brain barrier using electrostatics. Front Cell Neurosci (2012) 0.79

Improvement of HIV fusion inhibitor C34 efficacy by membrane anchoring and enhanced exposure. J Antimicrob Chemother (2014) 0.79

Neuropeptide Kyotorphin (Tyrosyl-Arginine) has Decreased Levels in the Cerebro-Spinal Fluid of Alzheimer's Disease Patients: Potential Diagnostic and Pharmacological Implications. Front Aging Neurosci (2013) 0.79