Published in Biochim Biophys Acta on February 12, 2010
Genetics of salt-sensitive hypertension. Curr Hypertens Rep (2011) 1.21
Diagnostic tools for hypertension and salt sensitivity testing. Curr Opin Nephrol Hypertens (2013) 1.21
Proximal nephron. Compr Physiol (2013) 1.02
Dopamine, the kidney, and hypertension. Curr Hypertens Rep (2012) 0.99
Abnormalities in renal dopamine signaling and hypertension: the role of GRK4. Curr Opin Nephrol Hypertens (2012) 0.97
Renal dopamine receptors, oxidative stress, and hypertension. Int J Mol Sci (2013) 0.96
Role of GRK4 in the regulation of arterial AT1 receptor in hypertension. Hypertension (2013) 0.95
Altered functioning of both renal dopamine D1 and angiotensin II type 1 receptors causes hypertension in old rats. Hypertension (2012) 0.95
Deficient dopamine D2 receptor function causes renal inflammation independently of high blood pressure. PLoS One (2012) 0.90
Common variants of the G protein-coupled receptor type 4 are associated with human essential hypertension and predict the blood pressure response to angiotensin receptor blockade. Pharmacogenomics J (2015) 0.89
The renal dopaminergic system: novel diagnostic and therapeutic approaches in hypertension and kidney disease. Transl Res (2014) 0.88
A linear relationship between the ex-vivo sodium mediated expression of two sodium regulatory pathways as a surrogate marker of salt sensitivity of blood pressure in exfoliated human renal proximal tubule cells: the virtual renal biopsy. Clin Chim Acta (2013) 0.88
Physiologic and pathophysiologic roles of cyclooxygenase-2 in the kidney. Trans Am Clin Climatol Assoc (2013) 0.87
Novel role of sorting nexin 5 in renal D(1) dopamine receptor trafficking and function: implications for hypertension. FASEB J (2012) 0.87
Genomics and Pharmacogenomics of Salt-sensitive Hypertension. Curr Hypertens Rev (2015) 0.86
FXR agonist INT-747 upregulates DDAH expression and enhances insulin sensitivity in high-salt fed Dahl rats. PLoS One (2013) 0.83
Blood pressure decrease in spontaneously hypertensive rats folowing renal denervation or dopamine β-hydroxylase inhibition with etamicastat. Hypertens Res (2015) 0.83
The dopamine D3 receptor knockout mouse mimics aging-related changes in autonomic function and cardiac fibrosis. PLoS One (2013) 0.82
Genome-wide meta-analysis of systolic blood pressure in children with sickle cell disease. PLoS One (2013) 0.81
Regulation of blood pressure, oxidative stress and AT1R by high salt diet in mutant human dopamine D5 receptor transgenic mice. Hypertens Res (2015) 0.78
Characteristic expressions of GABA receptors and GABA producing/transporting molecules in rat kidney. PLoS One (2014) 0.77
The Role of Aldosterone in Obesity-Related Hypertension. Am J Hypertens (2016) 0.77
New insights into sodium transport regulation in the distal nephron: Role of G-protein coupled receptors. World J Biol Chem (2016) 0.76
Structure and Function of the Hypertension Variant A486V of G Protein-coupled Receptor Kinase 4. J Biol Chem (2015) 0.76
Genomics and pharmacogenomics of salt-sensitive hypertension Minireview. Curr Hypertens Rev (2015) 0.75
Human disposition, metabolism and excretion of etamicastat, a reversible, peripherally selective dopamine β-hydroxylase inhibitor. Br J Clin Pharmacol (2014) 0.75
Increased renal oxidative stress in salt-sensitive human GRK4γ486V transgenic mice. Free Radic Biol Med (2017) 0.75
Variation in genes that regulate blood pressure are associated with glomerular filtration rate in Chinese. PLoS One (2014) 0.75
Urinary Dopamine as a Potential Index of the Transport Activity of Multidrug and Toxin Extrusion in the Kidney. Int J Mol Sci (2016) 0.75
Dopamine regulates renal osmoregulation during hyposaline stress via DRD1 in the spotted scat (Scatophagus argus). Sci Rep (2016) 0.75
Association between GRK4 and DRD1 gene polymorphisms and hypertension: a meta-analysis. Clin Interv Aging (2015) 0.75
Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44
Genome-wide association study of blood pressure and hypertension. Nat Genet (2009) 11.54
A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits. Nat Genet (2009) 7.65
Finding genes that underlie complex traits. Science (2002) 7.39
Desensitization of G protein-coupled receptors and neuronal functions. Annu Rev Neurosci (2004) 4.44
A genome-wide association study of hypertension and blood pressure in African Americans. PLoS Genet (2009) 4.28
New strategies for identifying gene-gene interactions in hypertension. Ann Med (2002) 4.19
Signal transduction mechanisms mediating the physiological and pathophysiological actions of angiotensin II in vascular smooth muscle cells. Pharmacol Rev (2000) 3.40
From the Cover: Whole-genome association study identifies STK39 as a hypertension susceptibility gene. Proc Natl Acad Sci U S A (2008) 3.39
G protein-coupled receptor kinase 4 gene variants in human essential hypertension. Proc Natl Acad Sci U S A (2002) 1.87
Use of phospho-specific antibodies to determine the phosphorylation of endogenous Na+/H+ exchanger NHE3 at PKA consensus sites. Am J Physiol Renal Physiol (2005) 1.84
Multilocus analysis of hypertension: a hierarchical approach. Hum Hered (2004) 1.82
G protein-coupled receptor kinase GRK4. Molecular analysis of the four isoforms and ultrastructural localization in spermatozoa and germinal cells. J Biol Chem (1997) 1.78
The D1 dopamine receptor is constitutively phosphorylated by G protein-coupled receptor kinase 4. Mol Pharmacol (2005) 1.75
G-protein-coupled receptor kinase 4 polymorphisms and blood pressure response to metoprolol among African Americans: sex-specificity and interactions. Am J Hypertens (2009) 1.66
Population-based sample reveals gene-gender interactions in blood pressure in White Americans. Hypertension (2006) 1.64
G protein-coupled receptor kinase 2 expression and activity are associated with blood pressure in black Americans. Hypertension (2009) 1.62
Renal dopamine receptors and hypertension. Exp Biol Med (Maywood) (2003) 1.61
alpha-Adducin Gly460Trp polymorphism is associated with low renin hypertension in younger subjects in the Ohasama study. J Hypertens (2002) 1.55
Evidence that intrarenal dopamine acts as a paracrine substance at the renal tubule. Am J Physiol (1989) 1.55
Single-nucleotide polymorphisms for diagnosis of salt-sensitive hypertension. Clin Chem (2006) 1.51
Combinations of variations in multiple genes are associated with hypertension. Hypertension (2000) 1.51
Characterization of the G protein-coupled receptor kinase GRK4. Identification of four splice variants. J Biol Chem (1996) 1.49
Prolactin and dopamine: what is the connection? A review article. J Psychopharmacol (2008) 1.45
Dopamine-induced recruitment of dopamine D1 receptors to the plasma membrane. Proc Natl Acad Sci U S A (1998) 1.45
Mechanisms of disease: the role of GRK4 in the etiology of essential hypertension and salt sensitivity. Nat Clin Pract Nephrol (2006) 1.40
Vascular-targeted overexpression of G protein-coupled receptor kinase-2 in transgenic mice attenuates beta-adrenergic receptor signaling and increases resting blood pressure. Mol Pharmacol (2002) 1.38
Differential regulation of dopamine D1A receptor responsiveness by various G protein-coupled receptor kinases. J Biol Chem (1996) 1.37
Phenotypic analysis of dopamine receptor knockout mice; recent insights into the functional specificity of dopamine receptor subtypes. Neuropharmacology (2004) 1.37
Functional genomics of the dopaminergic system in hypertension. Physiol Genomics (2004) 1.32
Effects of dietary sodium and of acute saline infusion on the interrelationship between dopamine excretion and adrenergic activity in man. J Clin Invest (1974) 1.32
D5 dopamine receptor regulation of reactive oxygen species production, NADPH oxidase, and blood pressure. Am J Physiol Regul Integr Comp Physiol (2006) 1.32
Dopamine 5 receptor mediates Ang II type 1 receptor degradation via a ubiquitin-proteasome pathway in mice and human cells. J Clin Invest (2008) 1.31
Association study with 33 single-nucleotide polymorphisms in 11 candidate genes for hypertension in Chinese. Hypertension (2006) 1.30
Phosphorylation-independent desensitization of GABA(B) receptor by GRK4. EMBO J (2003) 1.30
G protein-coupled receptor kinase-mediated phosphorylation regulates post-endocytic trafficking of the D2 dopamine receptor. J Biol Chem (2009) 1.27
Association of G-protein-coupled receptor kinase 4 haplotypes, but not HSD3B1 or PTP1B polymorphisms, with essential hypertension. J Hypertens (2004) 1.27
Analysis of Na+,K+-ATPase motion and incorporation into the plasma membrane in response to G protein-coupled receptor signals in living cells. Mol Biol Cell (2003) 1.25
The dopamine-1 agonist, SKF 82526, stimulates phospholipase-C activity independent of adenylate cyclase. J Pharmacol Exp Ther (1989) 1.25
Patterns of genetic variation in the hypertension candidate gene GRK4: ethnic variation and haplotype structure. Ann Hum Genet (2006) 1.23
The kinase Grk2 regulates Nedd4/Nedd4-2-dependent control of epithelial Na+ channels. Proc Natl Acad Sci U S A (2004) 1.23
Amelioration of genetic hypertension by suppression of renal G protein-coupled receptor kinase type 4 expression. Hypertension (2006) 1.22
G-Protein-coupled receptor kinase activity in hypertension : increased vascular and lymphocyte G-protein receptor kinase-2 protein expression. Hypertension (2000) 1.22
Dysregulation of dopamine-dependent mechanisms as a determinant of hypertension: studies in dopamine receptor knockout mice. Am J Physiol Heart Circ Physiol (2007) 1.21
Genotyping of essential hypertension single-nucleotide polymorphisms by a homogeneous PCR method with universal energy transfer primers. Clin Chem (2002) 1.20
D5 dopamine receptors are required for dopaminergic activation of phospholipase C. Mol Pharmacol (2008) 1.19
Calcium signaling by dopamine D5 receptor and D5-D2 receptor hetero-oligomers occurs by a mechanism distinct from that for dopamine D1-D2 receptor hetero-oligomers. Mol Pharmacol (2009) 1.19
Galpha12- and Galpha13-protein subunit linkage of D5 dopamine receptors in the nephron. Hypertension (2003) 1.17
Dopamine activates amiloride-sensitive sodium channels in alveolar type I cells in lung slice preparations. Am J Physiol Lung Cell Mol Physiol (2006) 1.17
The role of phosphorylation/dephosphorylation in agonist-induced desensitization of D1 dopamine receptor function: evidence for a novel pathway for receptor dephosphorylation. Mol Pharmacol (2001) 1.17
Perturbation of D1 dopamine and AT1 receptor interaction in spontaneously hypertensive rats. Hypertension (2003) 1.16
Desensitization of human renal D1 dopamine receptors by G protein-coupled receptor kinase 4. Kidney Int (2002) 1.16
The GRAFS classification system of G-protein coupled receptors in comparative perspective. Gen Comp Endocrinol (2005) 1.16
Genome scan for blood pressure in Dutch dyslipidemic families reveals linkage to a locus on chromosome 4p. Hypertension (2001) 1.16
Reactive oxygen species-dependent hypertension in dopamine D2 receptor-deficient mice. Hypertension (2006) 1.15
Calcium-sensing receptor regulation of PTH-inhibitable proximal tubule phosphate transport. Am J Physiol Renal Physiol (2003) 1.15
Members of the G protein-coupled receptor kinase family that phosphorylate the beta2-adrenergic receptor facilitate sequestration. Biochemistry (1996) 1.14
Impaired renal D(1)-like and D(2)-like dopamine receptor interaction in the spontaneously hypertensive rat. Am J Physiol Regul Integr Comp Physiol (2001) 1.13
Role of kidney dopamine in the natriuretic response to volume expansion in rats. Hypertension (1989) 1.12
Sequestration of dopamine D2 receptors depends on coexpression of G-protein-coupled receptor kinases 2 or 5. Eur J Biochem (1999) 1.12
Activation of dopamine D1-like receptors induces acute internalization of the renal Na+/phosphate cotransporter NaPi-IIa in mouse kidney and OK cells. Am J Physiol Renal Physiol (2004) 1.11
Dopamine acutely decreases apical membrane Na/H exchanger NHE3 protein in mouse renal proximal tubule. Kidney Int (2003) 1.11
Signaling pathways utilized by PTH and dopamine to inhibit phosphate transport in mouse renal proximal tubule cells. Am J Physiol Renal Physiol (2008) 1.10
Negative reciprocity between angiotensin II type 1 and dopamine D1 receptors in rat renal proximal tubule cells. Am J Physiol Renal Physiol (2008) 1.09
Sequestration of human muscarinic acetylcholine receptor hm1-hm5 subtypes: effect of G protein-coupled receptor kinases GRK2, GRK4, GRK5 and GRK6. J Pharmacol Exp Ther (1998) 1.09
Vascular smooth muscle overexpression of G protein-coupled receptor kinase 5 elevates blood pressure, which segregates with sex and is dependent on Gi-mediated signaling. Circulation (2005) 1.08
Attenuated renal response to dopaminergic drugs in spontaneously hypertensive rats. Hypertension (1990) 1.08
Proteomic analysis of long-term vasopressin action in the inner medullary collecting duct of the Brattleboro rat. Am J Physiol Renal Physiol (2003) 1.08
Blood pressure and renal sodium handling in relation to genetic variation in the DRD1 promoter and GRK4. Hypertension (2008) 1.08
Lipid rafts keep NADPH oxidase in the inactive state in human renal proximal tubule cells. Hypertension (2008) 1.07
G protein-coupled receptor kinase 4 (GRK4) regulates the phosphorylation and function of the dopamine D3 receptor. J Biol Chem (2009) 1.06
D1 dopamine receptor hyperphosphorylation in renal proximal tubules in hypertension. Kidney Int (2006) 1.06
Beta-arrestin- and G protein receptor kinase-mediated calcium-sensing receptor desensitization. Mol Endocrinol (2005) 1.05
The dopamine paradox in lung and kidney epithelia: sharing the same target but operating different signaling networks. Am J Respir Cell Mol Biol (2005) 1.05
Stimulated D(1) dopamine receptors couple to multiple Galpha proteins in different brain regions. J Neurochem (2001) 1.04
The Salted Food Addiction Hypothesis may explain overeating and the obesity epidemic. Med Hypotheses (2009) 1.02
The GRK4 subfamily of G protein-coupled receptor kinases. Alternative splicing, gene organization, and sequence conservation. J Biol Chem (1999) 1.02
Monoclonal antibodies reveal receptor specificity among G-protein-coupled receptor kinases. Proc Natl Acad Sci U S A (1996) 1.02
Role of G protein-coupled receptor kinase 4 and beta-arrestin 1 in agonist-stimulated metabotropic glutamate receptor 1 internalization and activation of mitogen-activated protein kinases. J Biol Chem (2003) 1.01
The 14-3-3 protein translates the NA+,K+-ATPase {alpha}1-subunit phosphorylation signal into binding and activation of phosphoinositide 3-kinase during endocytosis. J Biol Chem (2005) 1.01
Characterization of the desensitization properties of five dopamine receptor subtypes and alternatively spliced variants of dopamine D2 and D4 receptors. Biochem Biophys Res Commun (2006) 1.00
Drugs in the medical treatment of Cushing's syndrome. Expert Opin Emerg Drugs (2009) 1.00
G protein-coupled receptor kinase regulates dopamine D3 receptor signaling by modulating the stability of a receptor-filamin-beta-arrestin complex. A case of autoreceptor regulation. J Biol Chem (2005) 1.00
Dopamine regulates Na-K-ATPase in alveolar epithelial cells via MAPK-ERK-dependent mechanisms. Am J Physiol Lung Cell Mol Physiol (2001) 0.99
Behavioral sensitization, alternative splicing, and d3 dopamine receptor-mediated inhibitory function. Neuropsychopharmacology (2006) 0.99
Rosiglitazone restores renal D1A receptor-Gs protein coupling by reducing receptor hyperphosphorylation in obese rats. Am J Physiol Renal Physiol (2005) 0.98
Caveolin-1 and dopamine-mediated internalization of NaKATPase in human renal proximal tubule cells. Hypertension (2009) 0.98
Intrarenal dopamine production and distribution in the rat. Physiological control of sodium excretion. Hypertension (1997) 0.98
Arrestins and spinophilin competitively regulate Na+,K+-ATPase trafficking through association with a large cytoplasmic loop of the Na+,K+-ATPase. Mol Biol Cell (2007) 0.98
Angiotensin II regulation of AT1 and D3 dopamine receptors in renal proximal tubule cells of SHR. Hypertension (2002) 0.97
Interaction of MAP17 with NHERF3/4 induces translocation of the renal Na/Pi IIa transporter to the trans-Golgi. Am J Physiol Renal Physiol (2006) 0.97
Renal dopaminergic defect in C57Bl/6J mice. Am J Physiol Regul Integr Comp Physiol (2009) 0.97
The G protein-coupled receptor kinase 4 gene modulates stress-induced sodium excretion in black normotensive adolescents. Pediatr Res (2006) 0.96
Phosphorylation-independent desensitization of G protein-coupled receptors? Sci STKE (2002) 0.96
Palmitoylation of the luteinizing hormone/human chorionic gonadotropin receptor regulates receptor interaction with the arrestin-mediated internalization pathway. Eur J Biochem (2001) 0.96
G protein-coupled receptor kinase 5 in cultured vascular smooth muscle cells and rat aorta. Regulation by angiotensin II and hypertension. J Biol Chem (1997) 0.95
The elevated blood pressure of human GRK4gamma A142V transgenic mice is not associated with increased ROS production. Am J Physiol Heart Circ Physiol (2007) 0.95
Inhibition of Na,K-ATPase by dopamine in proximal tubule epithelial cells. Semin Nephrol (2005) 0.95
Interaction between dopamine and its transporter: role of intracellular sodium ions and membrane potential. J Neurochem (2004) 0.95
Short telomeres and prognosis of hypertension in a chinese population. Hypertension (2009) 2.18
G protein-coupled receptor kinase 4 gene variants in human essential hypertension. Proc Natl Acad Sci U S A (2002) 1.87
Multilocus analysis of hypertension: a hierarchical approach. Hum Hered (2004) 1.82
Renal D3 dopamine receptor stimulation induces natriuresis by endothelin B receptor interactions. Kidney Int (2008) 1.63
Single-nucleotide polymorphisms for diagnosis of salt-sensitive hypertension. Clin Chem (2006) 1.51
Preanalytical errors introduced by sample-transportation systems: a means to assess them. Clin Chem (2011) 1.48
Activation of D3 dopamine receptor decreases angiotensin II type 1 receptor expression in rat renal proximal tubule cells. Circ Res (2006) 1.36
Functional genomics of the dopaminergic system in hypertension. Physiol Genomics (2004) 1.32
D5 dopamine receptor regulation of reactive oxygen species production, NADPH oxidase, and blood pressure. Am J Physiol Regul Integr Comp Physiol (2006) 1.32
Dopamine 5 receptor mediates Ang II type 1 receptor degradation via a ubiquitin-proteasome pathway in mice and human cells. J Clin Invest (2008) 1.31
Salt sensitivity of blood pressure is associated with polymorphisms in the sodium-bicarbonate cotransporter. Hypertension (2012) 1.30
Development and preliminary validation of heart rate and breathing rate detection using a passive, ballistocardiography-based sleep monitoring system. IEEE Trans Inf Technol Biomed (2009) 1.29
D1 dopamine receptor signaling involves caveolin-2 in HEK-293 cells. Kidney Int (2004) 1.28
3D cell culture opens new dimensions in cell-based assays. Drug Discov Today (2008) 1.26
Mice lacking D5 dopamine receptors have increased sympathetic tone and are hypertensive. J Neurosci (2002) 1.25
Amelioration of genetic hypertension by suppression of renal G protein-coupled receptor kinase type 4 expression. Hypertension (2006) 1.22
Interaction of angiotensin II type 1 and D5 dopamine receptors in renal proximal tubule cells. Hypertension (2005) 1.22
Dysregulation of dopamine-dependent mechanisms as a determinant of hypertension: studies in dopamine receptor knockout mice. Am J Physiol Heart Circ Physiol (2007) 1.21
Intrarenal dopamine D1-like receptor stimulation induces natriuresis via an angiotensin type-2 receptor mechanism. Hypertension (2006) 1.20
Genotyping of essential hypertension single-nucleotide polymorphisms by a homogeneous PCR method with universal energy transfer primers. Clin Chem (2002) 1.20
Galpha12- and Galpha13-protein subunit linkage of D5 dopamine receptors in the nephron. Hypertension (2003) 1.17
Perturbation of D1 dopamine and AT1 receptor interaction in spontaneously hypertensive rats. Hypertension (2003) 1.16
Desensitization of human renal D1 dopamine receptors by G protein-coupled receptor kinase 4. Kidney Int (2002) 1.16
Differential D1 and D5 receptor regulation and degradation of the angiotensin type 1 receptor. Hypertension (2008) 1.11
Salt sensitivity is associated with insulin resistance, sympathetic overactivity, and decreased suppression of circulating renin activity in lean patients with essential hypertension. Am J Clin Nutr (2010) 1.11
Angiotensin-II type 1 receptor-mediated hypertension in D4 dopamine receptor-deficient mice. Hypertension (2005) 1.08
Lipid rafts keep NADPH oxidase in the inactive state in human renal proximal tubule cells. Hypertension (2008) 1.07
Dopamine, kidney, and hypertension: studies in dopamine receptor knockout mice. Pediatr Nephrol (2008) 1.07
G protein-coupled receptor kinase 4 (GRK4) regulates the phosphorylation and function of the dopamine D3 receptor. J Biol Chem (2009) 1.06
Role of dopamine receptors in the kidney in the regulation of blood pressure. Curr Opin Nephrol Hypertens (2002) 1.06
The dopaminergic system in hypertension. Clin Sci (Lond) (2007) 1.06
Dopamine and the kidney: a role in hypertension? Curr Opin Nephrol Hypertens (2003) 1.05
Long-term safety and efficacy of eslicarbazepine acetate as adjunctive therapy in the treatment of partial-onset seizures in adults with epilepsy: results of a 1-year open-label extension study. Epilepsy Res (2012) 1.03
Effects of sulodexide in patients with type 2 diabetes and persistent albuminuria. Nephrol Dial Transplant (2007) 1.01
Insulin promotes vascular smooth muscle cell proliferation via microRNA-208-mediated downregulation of p21. J Hypertens (2011) 1.00
Production and role of extracellular guanosine cyclic 3', 5' monophosphate in sodium uptake in human proximal tubule cells. Hypertension (2004) 0.99
Regulation of blood pressure by dopamine receptors. Nephron Physiol (2003) 0.99
Urinary exosome miRNome analysis and its applications to salt sensitivity of blood pressure. Clin Biochem (2013) 0.99
Pharmacokinetics and drug interactions of eslicarbazepine acetate. Epilepsia (2012) 0.98
Caveolin-1 and dopamine-mediated internalization of NaKATPase in human renal proximal tubule cells. Hypertension (2009) 0.98
Extracellular vesicle-mediated transfer of donor genomic DNA to recipient cells is a novel mechanism for genetic influence between cells. J Mol Cell Biol (2013) 0.98
Angiotensin II regulation of AT1 and D3 dopamine receptors in renal proximal tubule cells of SHR. Hypertension (2002) 0.97
Dopamine and angiotensin type 2 receptors cooperatively inhibit sodium transport in human renal proximal tubule cells. Hypertension (2012) 0.97
Long-term efficacy and safety of eslicarbazepine acetate: results of a 1-year open-label extension study in partial-onset seizures in adults with epilepsy. Epilepsia (2010) 0.96
The elevated blood pressure of human GRK4gamma A142V transgenic mice is not associated with increased ROS production. Am J Physiol Heart Circ Physiol (2007) 0.95
Angiotensin III stimulates aldosterone secretion from adrenal gland partially via angiotensin II type 2 receptor but not angiotensin II type 1 receptor. Endocrinology (2011) 0.95
Upregulation of renal sodium transporters in D5 dopamine receptor-deficient mice. Hypertension (2010) 0.95
Paraoxonase 2 decreases renal reactive oxygen species production, lowers blood pressure, and mediates dopamine D2 receptor-induced inhibition of NADPH oxidase. Free Radic Biol Med (2012) 0.94
Synthesis and biological evaluation of novel, peripherally selective chromanyl imidazolethione-based inhibitors of dopamine beta-hydroxylase. J Med Chem (2006) 0.93
Angiotensin II type 1 receptor blocker attenuates the activation of ERK and NADPH oxidase by mechanical strain in mesangial cells in the absence of angiotensin II. Am J Physiol Renal Physiol (2009) 0.93
Dopamine D1 receptor augmentation of D3 receptor action in rat aortic or mesenteric vascular smooth muscles. Hypertension (2004) 0.93
HK-2 human renal proximal tubule cells as a model for G protein-coupled receptor kinase type 4-mediated dopamine 1 receptor uncoupling. Hypertension (2010) 0.93
Rat strain effects of AT1 receptor activation on D1 dopamine receptors in immortalized renal proximal tubule cells. Hypertension (2005) 0.92
Aldosterone/Mineralocorticoid receptor stimulation induces cellular senescence in the kidney. Endocrinology (2010) 0.92
Rab4 and Rab11 coordinately regulate the recycling of angiotensin II type I receptor as demonstrated by fluorescence resonance energy transfer microscopy. J Biomed Opt (2008) 0.91
D1-like receptors regulate NADPH oxidase activity and subunit expression in lipid raft microdomains of renal proximal tubule cells. Hypertension (2009) 0.91
Differential effects of angiotensin II type-1 receptor antisense oligonucleotides on renal function in spontaneously hypertensive rats. Hypertension (2005) 0.91
Renal interstitial guanosine cyclic 3', 5'-monophosphate mediates pressure-natriuresis via protein kinase G. Hypertension (2004) 0.90
High body mass index is an important risk factor for the development of type 2 diabetes. Intern Med (2012) 0.90
D3 dopamine receptor directly interacts with D1 dopamine receptor in immortalized renal proximal tubule cells. Hypertension (2006) 0.90
G protein-coupled receptor kinase 4: role in blood pressure regulation. Hypertension (2008) 0.90
Inhibitory effect of ETB receptor on Na(+)-K(+) ATPase activity by extracellular Ca(2+) entry and Ca(2+) release from the endoplasmic reticulum in renal proximal tubule cells. Hypertens Res (2009) 0.89
D5 dopamine receptor decreases NADPH oxidase, reactive oxygen species and blood pressure via heme oxygenase-1. Hypertens Res (2013) 0.89
D5 dopamine receptor regulation of phospholipase D. Am J Physiol Heart Circ Physiol (2005) 0.89
Effects of decreased renal cortical expression of G protein-coupled receptor kinase 4 and angiotensin type 1 receptors in rats. Hypertens Res (2008) 0.89
Isolation, growth, and characterization of human renal epithelial cells using traditional and 3D methods. Methods Mol Biol (2013) 0.88
A linear relationship between the ex-vivo sodium mediated expression of two sodium regulatory pathways as a surrogate marker of salt sensitivity of blood pressure in exfoliated human renal proximal tubule cells: the virtual renal biopsy. Clin Chim Acta (2013) 0.88
Single-nucleotide polymorphisms of the dopamine D2 receptor increase inflammation and fibrosis in human renal proximal tubule cells. Hypertension (2013) 0.88
Achievement status toward goal blood pressure levels and healthy lifestyles among Japanese hypertensive patients; cross-sectional survey results from Fukushima Research of Hypertension (FRESH). Intern Med (2011) 0.87
Dopamine receptor and hypertension. Curr Med Chem Cardiovasc Hematol Agents (2005) 0.87
D3 dopamine receptor regulation of ETB receptors in renal proximal tubule cells from WKY and SHRs. Am J Hypertens (2009) 0.87
Hypertension-Related Gene Polymorphisms of G-Protein-Coupled Receptor Kinase 4 Are Associated with NT-proBNP Concentration in Normotensive Healthy Adults. Int J Hypertens (2012) 0.86
Altered AT1 receptor regulation of ETB receptors in renal proximal tubule cells of spontaneously hypertensive rats. Hypertension (2005) 0.86
Safety, tolerability, and pharmacokinetics of etamicastat, a novel dopamine-β-hydroxylase inhibitor, in a rising multiple-dose study in young healthy subjects. Drugs R D (2010) 0.85
Sorting nexin 1 loss results in D5 dopamine receptor dysfunction in human renal proximal tubule cells and hypertension in mice. J Biol Chem (2012) 0.84
A new approach for treatment of hypertension: modifying D1 dopamine receptor function. Cardiovasc Hematol Agents Med Chem (2006) 0.84
Aberrant D1 and D3 dopamine receptor transregulation in hypertension. Hypertension (2004) 0.84
Pharmacokinetics and tolerability of etamicastat following single and repeated administration in elderly versus young healthy male subjects: an open-label, single-center, parallel-group study. Clin Ther (2011) 0.82
Dopamine D1 receptor-mediated inhibition of NADPH oxidase activity in human kidney cells occurs via protein kinase A-protein kinase C cross talk. Free Radic Biol Med (2010) 0.82