PubRank

Jeffrey N Weiser

Author PubWeight™ 101.27‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The role of Streptococcus pneumoniae virulence factors in host respiratory colonization and disease. Nat Rev Microbiol 2008 5.98
2 Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity. Nat Med 2010 4.98
3 Cellular effectors mediating Th17-dependent clearance of pneumococcal colonization in mice. J Clin Invest 2009 3.16
4 The immune response to pneumococcal proteins during experimental human carriage. J Exp Med 2002 3.03
5 Limited role of antibody in clearance of Streptococcus pneumoniae in a murine model of colonization. Infect Immun 2004 2.53
6 The role of innate immune responses in the outcome of interspecies competition for colonization of mucosal surfaces. PLoS Pathog 2005 2.41
7 Host and bacterial factors contributing to the clearance of colonization by Streptococcus pneumoniae in a murine model. Infect Immun 2005 2.32
8 Deglycosylation of human glycoconjugates by the sequential activities of exoglycosidases expressed by Streptococcus pneumoniae. Mol Microbiol 2006 2.29
9 Factors contributing to hydrogen peroxide resistance in Streptococcus pneumoniae include pyruvate oxidase (SpxB) and avoidance of the toxic effects of the fenton reaction. J Bacteriol 2003 2.20
10 Capsule enhances pneumococcal colonization by limiting mucus-mediated clearance. Infect Immun 2006 2.15
11 Minimization of bacterial size allows for complement evasion and is overcome by the agglutinating effect of antibody. Cell Host Microbe 2011 2.03
12 Phase variable desialylation of host proteins that bind to Streptococcus pneumoniae in vivo and protect the airway. Mol Microbiol 2004 1.97
13 Within-host competition drives selection for the capsule virulence determinant of Streptococcus pneumoniae. Curr Biol 2010 1.92
14 Epithelial cells are sensitive detectors of bacterial pore-forming toxins. J Biol Chem 2006 1.90
15 Toll-like receptor 4 mediates innate immune responses to Haemophilus influenzae infection in mouse lung. J Immunol 2002 1.88
16 Serum immunoglobulin G response to candidate vaccine antigens during experimental human pneumococcal colonization. Infect Immun 2003 1.83
17 Live attenuated Streptococcus pneumoniae strains induce serotype-independent mucosal and systemic protection in mice. Infect Immun 2007 1.83
18 Synergistic stimulation of type I interferons during influenza virus coinfection promotes Streptococcus pneumoniae colonization in mice. J Clin Invest 2011 1.79
19 The blp bacteriocins of Streptococcus pneumoniae mediate intraspecies competition both in vitro and in vivo. Infect Immun 2006 1.75
20 Short-sequence tandem and nontandem DNA repeats and endogenous hydrogen peroxide production contribute to genetic instability of Streptococcus pneumoniae. J Bacteriol 2002 1.69
21 Synergistic proinflammatory responses induced by polymicrobial colonization of epithelial surfaces. Proc Natl Acad Sci U S A 2005 1.67
22 Klebsiella pneumoniae yersiniabactin promotes respiratory tract infection through evasion of lipocalin 2. Infect Immun 2011 1.66
23 Neutrophil-toxin interactions promote antigen delivery and mucosal clearance of Streptococcus pneumoniae. J Immunol 2008 1.58
24 Neuraminidase expressed by Streptococcus pneumoniae desialylates the lipopolysaccharide of Neisseria meningitidis and Haemophilus influenzae: a paradigm for interbacterial competition among pathogens of the human respiratory tract. Infect Immun 2002 1.57
25 beta-Defensin 1 contributes to pulmonary innate immunity in mice. Infect Immun 2002 1.57
26 Mucosal lipocalin 2 has pro-inflammatory and iron-sequestering effects in response to bacterial enterobactin. PLoS Pathog 2009 1.56
27 Inhibition of the pneumococcal virulence factor StrH and molecular insights into N-glycan recognition and hydrolysis. Structure 2011 1.53
28 Nod2 sensing of lysozyme-digested peptidoglycan promotes macrophage recruitment and clearance of S. pneumoniae colonization in mice. J Clin Invest 2011 1.53
29 Human neutrophils kill Streptococcus pneumoniae via serine proteases. J Immunol 2009 1.49
30 The inhibitory effect of C-reactive protein on bacterial phosphorylcholine platelet-activating factor receptor-mediated adherence is blocked by surfactant. J Infect Dis 2002 1.49
31 Nod1 signaling overcomes resistance of S. pneumoniae to opsonophagocytic killing. PLoS Pathog 2007 1.45
32 Bacterial colonization of nasal mucosa induces expression of siderocalin, an iron-sequestering component of innate immunity. Cell Microbiol 2005 1.36
33 Streptococcus pneumoniae resistance to complement-mediated immunity is dependent on the capsular serotype. Infect Immun 2009 1.35
34 Three surface exoglycosidases from Streptococcus pneumoniae, NanA, BgaA, and StrH, promote resistance to opsonophagocytic killing by human neutrophils. Infect Immun 2010 1.32
35 Nod1 mediates cytoplasmic sensing of combinations of extracellular bacteria. Cell Microbiol 2007 1.25
36 Modifications to the peptidoglycan backbone help bacteria to establish infection. Infect Immun 2010 1.22
37 Transcriptional profile of the Escherichia coli response to the antimicrobial insect peptide cecropin A. Antimicrob Agents Chemother 2003 1.20
38 Cross-reactivity of human immunoglobulin G2 recognizing phosphorylcholine and evidence for protection against major bacterial pathogens of the human respiratory tract. J Infect Dis 2004 1.15
39 The atypical amino-terminal LPNTG-containing domain of the pneumococcal human IgA1-specific protease is required for proper enzyme localization and function. Mol Microbiol 2006 1.11
40 Resistance to mucosal lysozyme compensates for the fitness deficit of peptidoglycan modifications by Streptococcus pneumoniae. PLoS Pathog 2008 1.11
41 Invasive bacterial pathogens exploit TLR-mediated downregulation of tight junction components to facilitate translocation across the epithelium. Cell Host Microbe 2011 1.10
42 Role of p38 MAP kinase and transforming growth factor-beta signaling in transepithelial migration of invasive bacterial pathogens. J Biol Chem 2007 1.07
43 Early bacterial colonization induces toll-like receptor-dependent transforming growth factor beta signaling in the epithelium. Infect Immun 2009 1.03
44 Interaction of lipocalin 2, transferrin, and siderophores determines the replicative niche of Klebsiella pneumoniae during pneumonia. MBio 2012 1.02
45 Bacteriocin activity of Streptococcus pneumoniae is controlled by the serine protease HtrA via posttranscriptional regulation. J Bacteriol 2008 1.02
46 Pneumococcal surface protein A inhibits complement deposition on the pneumococcal surface by competing with the binding of C-reactive protein to cell-surface phosphocholine. J Immunol 2012 1.01
47 MARCO is required for TLR2- and Nod2-mediated responses to Streptococcus pneumoniae and clearance of pneumococcal colonization in the murine nasopharynx. J Immunol 2012 1.01
48 Conserved mutations in the pneumococcal bacteriocin transporter gene, blpA, result in a complex population consisting of producers and cheaters. MBio 2011 1.00
49 Increased chain length promotes pneumococcal adherence and colonization. Infect Immun 2012 0.99
50 Phosphorylcholine allows for evasion of bactericidal antibody by Haemophilus influenzae. PLoS Pathog 2012 0.99
51 Protection from the acquisition of Staphylococcus aureus nasal carriage by cross-reactive antibody to a pneumococcal dehydrogenase. Proc Natl Acad Sci U S A 2012 0.99
52 Co-infection subverts mucosal immunity in the upper respiratory tract. Curr Opin Immunol 2012 0.98
53 Identifying mutator phenotypes among fluoroquinolone-resistant strains of Streptococcus pneumoniae using fluctuation analysis. Antimicrob Agents Chemother 2007 0.98
54 Microbial modulation of host immunity with the small molecule phosphorylcholine. Infect Immun 2012 0.96
55 Interleukin-8 secretion in response to aferric enterobactin is potentiated by siderocalin. Infect Immun 2007 0.96
56 Intracellular sensors of extracellular bacteria. Immunol Rev 2011 0.95
57 Impact of the molecular form of immunoglobulin A on functional activity in defense against Streptococcus pneumoniae. Infect Immun 2007 0.93
58 Identification of the targets of cross-reactive antibodies induced by Streptococcus pneumoniae colonization. Infect Immun 2010 0.92
59 Mechanisms of Bacterial Colonization of the Respiratory Tract. Annu Rev Microbiol 2015 0.91
60 Mucosal clearance of capsule-expressing bacteria requires both TLR and nucleotide-binding oligomerization domain 1 signaling. J Immunol 2008 0.91
61 Natural antibody to conserved targets of Haemophilus influenzae limits colonization of the murine nasopharynx. Infect Immun 2009 0.90
62 Multiple mechanisms for choline transport and utilization in Haemophilus influenzae. Mol Microbiol 2003 0.88
63 Evasion of killing by human antibody and complement through multiple variations in the surface oligosaccharide of Haemophilus influenzae. Mol Microbiol 2013 0.87
64 Bacterial exploitation of phosphorylcholine mimicry suppresses inflammation to promote airway infection. J Clin Invest 2015 0.78
65 Binding of human factor H to outer membrane protein P5 of non-typeable Haemophilus influenzae contributes to complement resistance. Mol Microbiol 2014 0.78
66 Effect of pneumococcal polysaccharide vaccine on nonbacteremic pneumococcal pneumonia. Clin Infect Dis 2007 0.75