PubRank

Simon J Conway

Author PubWeight™ 132.50‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Fate mapping analysis reveals that adult microglia derive from primitive macrophages. Science 2010 12.15
2 In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes. Nature 2012 7.80
3 Genetic manipulation of periostin expression reveals a role in cardiac hypertrophy and ventricular remodeling. Circ Res 2007 4.53
4 Adult satellite cells and embryonic muscle progenitors have distinct genetic requirements. Nature 2009 3.72
5 Periostin regulates collagen fibrillogenesis and the biomechanical properties of connective tissues. J Cell Biochem 2007 3.53
6 periostin null mice exhibit dwarfism, incisor enamel defects, and an early-onset periodontal disease-like phenotype. Mol Cell Biol 2005 2.94
7 Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac-derived macrophages. J Exp Med 2012 2.69
8 BMP10 is essential for maintaining cardiac growth during murine cardiogenesis. Development 2004 2.50
9 Cardiac fibroblasts are essential for the adaptive response of the murine heart to pressure overload. J Clin Invest 2009 2.46
10 Periostin is required for maturation and extracellular matrix stabilization of noncardiomyocyte lineages of the heart. Circ Res 2008 2.44
11 Origin of cardiac fibroblasts and the role of periostin. Circ Res 2009 2.33
12 All primitive and definitive hematopoietic progenitor cells emerging before E10 in the mouse embryo are products of the yolk sac. Blood 2007 2.31
13 Muscle stem cell behavior is modified by microRNA-27 regulation of Pax3 expression. Proc Natl Acad Sci U S A 2009 2.28
14 Tbx1 is regulated by tissue-specific forkhead proteins through a common Sonic hedgehog-responsive enhancer. Genes Dev 2003 2.01
15 SDF-1 (CXCL12) is upregulated in the ischemic penumbra following stroke: association with bone marrow cell homing to injury. J Neuropathol Exp Neurol 2004 1.94
16 Altered Twist1 and Hand2 dimerization is associated with Saethre-Chotzen syndrome and limb abnormalities. Nat Genet 2005 1.89
17 VEGF: a modifier of the del22q11 (DiGeorge) syndrome? Nat Med 2003 1.79
18 Autonomous murine T-cell progenitor production in the extra-embryonic yolk sac before HSC emergence. Blood 2012 1.72
19 Periostin is expressed within the developing teeth at the sites of epithelial-mesenchymal interaction. Dev Dyn 2004 1.72
20 Regulation of beta catenin signaling and parathyroid hormone anabolic effects in bone by the matricellular protein periostin. Proc Natl Acad Sci U S A 2012 1.68
21 Hand2 loss-of-function in Hand1-expressing cells reveals distinct roles in epicardial and coronary vessel development. Circ Res 2011 1.57
22 Embryonic day 9 yolk sac and intra-embryonic hemogenic endothelium independently generate a B-1 and marginal zone progenitor lacking B-2 potential. Proc Natl Acad Sci U S A 2011 1.55
23 The loss of Nf1 transiently promotes self-renewal but not tumorigenesis by neural crest stem cells. Cancer Cell 2008 1.54
24 Periostin promotes chronic allergic inflammation in response to Th2 cytokines. J Clin Invest 2012 1.51
25 Phosphatidylinositol-3-kinase signaling mediates vascular smooth muscle cell expression of periostin in vivo and in vitro. Atherosclerosis 2005 1.48
26 Alk3/Bmpr1a receptor is required for development of the atrioventricular canal into valves and annulus fibrosus. Circ Res 2005 1.48
27 The matricellular protein periostin is required for sost inhibition and the anabolic response to mechanical loading and physical activity. J Biol Chem 2009 1.41
28 Serum response factor orchestrates nascent sarcomerogenesis and silences the biomineralization gene program in the heart. Proc Natl Acad Sci U S A 2008 1.39
29 Haemogenic endocardium contributes to transient definitive haematopoiesis. Nat Commun 2013 1.36
30 Cardiac-specific expression and hypertrophic upregulation of the feline Na(+)-Ca(2+) exchanger gene H1-promoter in a transgenic mouse model. Circ Res 2002 1.35
31 Identification and characterization of a novel Schwann and outflow tract endocardial cushion lineage-restricted periostin enhancer. Dev Biol 2007 1.35
32 Mutations within helix I of Twist1 result in distinct limb defects and variation of DNA binding affinities. J Biol Chem 2007 1.34
33 Periostin mediates vascular smooth muscle cell migration through the integrins alphavbeta3 and alphavbeta5 and focal adhesion kinase (FAK) pathway. Atherosclerosis 2009 1.33
34 Cardiogenic genes expressed in cardiac fibroblasts contribute to heart development and repair. Circ Res 2014 1.29
35 Cardiovascular development and the colonizing cardiac neural crest lineage. ScientificWorldJournal 2007 1.26
36 Periostin, a matricellular protein, plays a role in the induction of chemokines in pulmonary fibrosis. Am J Respir Cell Mol Biol 2012 1.24
37 An absence of Twist1 results in aberrant cardiac neural crest morphogenesis. Dev Biol 2008 1.22
38 Pax3-FKHR knock-in mice show developmental aberrations but do not develop tumors. Mol Cell Biol 2002 1.20
39 Comparison of the four mouse fasciclin-containing genes expression patterns during valvuloseptal morphogenesis. Gene Expr Patterns 2005 1.18
40 Transforming growth factor beta signaling in adult cardiovascular diseases and repair. Cell Tissue Res 2011 1.10
41 Lineage-specific responses to reduced embryonic Pax3 expression levels. Dev Biol 2007 1.10
42 Periostin modulates myofibroblast differentiation during full-thickness cutaneous wound repair. J Cell Sci 2012 1.09
43 Phosphoregulation of Twist1 provides a mechanism of cell fate control. Curr Med Chem 2008 1.09
44 Genetic and cellular evidence of vascular inflammation in neurofibromin-deficient mice and humans. J Clin Invest 2010 1.09
45 Lack of endothelial cell survivin causes embryonic defects in angiogenesis, cardiogenesis, and neural tube closure. Blood 2007 1.07
46 Transforming growth factor Beta2 is required for valve remodeling during heart development. Dev Dyn 2011 1.06
47 Lack of periostin leads to suppression of Notch1 signaling and calcific aortic valve disease. Physiol Genomics 2009 1.06
48 Cooperative interaction of Nkx2.5 and Mef2c transcription factors during heart development. Dev Dyn 2008 1.05
49 The LTR enhancer of ERV-9 human endogenous retrovirus is active in oocytes and progenitor cells in transgenic zebrafish and humans. Proc Natl Acad Sci U S A 2004 1.05
50 Generation of a conditional loxP allele of the Pax3 transcription factor that enables selective deletion of the homeodomain. Genesis 2002 1.01
51 Nf1+/- mice have increased neointima formation via hyperactivation of a Gleevec sensitive molecular pathway. Hum Mol Genet 2008 1.01
52 Pax3 is essential for normal cardiac neural crest morphogenesis but is not required during migration nor outflow tract septation. Dev Biol 2011 0.99
53 SWI/SNF complexes containing Brahma or Brahma-related gene 1 play distinct roles in smooth muscle development. Mol Cell Biol 2011 0.98
54 Periostin, a matricellular protein, accelerates cutaneous wound repair by activating dermal fibroblasts. Exp Dermatol 2012 0.96
55 Spatiotemporal expression of periostin during skin development and incisional wound healing: lessons for human fibrotic scar formation. J Cell Commun Signal 2010 0.96
56 Aberrant signaling pathways of the lung mesenchyme and their contributions to the pathogenesis of bronchopulmonary dysplasia. Birth Defects Res A Clin Mol Teratol 2011 0.95
57 Analysis of the Hand1 cell lineage reveals novel contributions to cardiovascular, neural crest, extra-embryonic, and lateral mesoderm derivatives. Dev Dyn 2010 0.94
58 Periostin regulates goblet cell metaplasia in a model of allergic airway inflammation. J Immunol 2011 0.93
59 Cardiac outflow tract anomalies. Wiley Interdiscip Rev Dev Biol 2013 0.92
60 HDAC1 and HDAC2 control the specification of neural crest cells into peripheral glia. J Neurosci 2014 0.91
61 Regulation of Ncx1 expression. Identification of regulatory elements mediating cardiac-specific expression and up-regulation. J Biol Chem 2006 0.90
62 Periostin deficiency increases bone damage and impairs injury response to fatigue loading in adult mice. PLoS One 2013 0.89
63 Assessment of inhibited alveolar-capillary membrane structural development and function in bronchopulmonary dysplasia. Birth Defects Res A Clin Mol Teratol 2014 0.87
64 The dynamic role of cardiac fibroblasts in development and disease. J Cardiovasc Transl Res 2012 0.87
65 Regulation of Ncx1 gene expression in the normal and hypertrophic heart. Ann N Y Acad Sci 2007 0.87
66 Intragenic deletion of Tgif causes defectsin brain development. Hum Mol Genet 2006 0.87
67 Trigenic neural crest-restricted Smad7 over-expression results in congenital craniofacial and cardiovascular defects. Dev Biol 2010 0.87
68 Fkbp1a controls ventricular myocardium trabeculation and compaction by regulating endocardial Notch1 activity. Development 2013 0.86
69 Periostin downregulation is an early marker of inhibited neonatal murine lung alveolar septation. Birth Defects Res A Clin Mol Teratol 2013 0.86
70 Periostin contributes to the pathogenesis of atopic dermatitis by inducing TSLP production from keratinocytes. Allergol Int 2012 0.86
71 Cyp1b1 mediates periostin regulation of trabecular meshwork development by suppression of oxidative stress. Mol Cell Biol 2013 0.86
72 Generation and characterization of Csrp1 enhancer-driven tissue-restricted Cre-recombinase mice. Genesis 2008 0.85
73 Heterozygous inactivation of the Nf1 gene in myeloid cells enhances neointima formation via a rosuvastatin-sensitive cellular pathway. Hum Mol Genet 2012 0.85
74 The haploinsufficient hematopoietic microenvironment is critical to the pathological fracture repair in murine models of neurofibromatosis type 1. PLoS One 2011 0.84
75 Developmental biology: the power of blood. Nature 2007 0.83
76 Chronic administration of KB-R7943 induces up-regulation of cardiac NCX1. J Biol Chem 2009 0.82
77 Notochordal and foregut abnormalities correlate with elevated neural crest apoptosis in Patch embryos. Birth Defects Res A Clin Mol Teratol 2011 0.82
78 Combinatorial transcriptional interaction within the cardiac neural crest: a pair of HANDs in heart formation. Birth Defects Res C Embryo Today 2004 0.81
79 Probing human cardiovascular congenital disease using transgenic mouse models. Prog Mol Biol Transl Sci 2011 0.81
80 Characterization of Pax3-expressing cells from adult blood vessels. J Cell Sci 2011 0.81
81 Generation of Smad7(-Cre) recombinase mice: A useful tool for the study of epithelial-mesenchymal transformation within the embryonic heart. Genesis 2009 0.79
82 In vitro requirement for periostin in B lymphopoiesis. Blood 2011 0.79
83 In situ hybridization (both radioactive and nonradioactive) and spatiotemporal gene expression analysis. Methods Mol Biol 2014 0.78
84 SHP-2 deletion in postmigratory neural crest cells results in impaired cardiac sympathetic innervation. Proc Natl Acad Sci U S A 2014 0.78
85 Gene replacement strategies to test the functional redundancy of basic helix-loop-helix transcription factor. Pediatr Cardiol 2010 0.77
86 Pathways regulating Na+/Ca2+ exchanger expression in the heart. Ann N Y Acad Sci 2002 0.77
87 Current state of congenital heart research and clues to future directions. Birth Defects Res A Clin Mol Teratol 2011 0.75
88 Neurofibromin-deficient myeloid cells are critical mediators of aneurysm formation in vivo. Circulation 2013 0.75
89 Developmental determinants and changing patterns of respiratory outcomes after preterm birth. Birth Defects Res A Clin Mol Teratol 2014 0.75
90 Persistent Noggin arrests cardiomyocyte morphogenesis and results in early in utero lethality. Dev Dyn 2014 0.75