PubRank

Luc Girard

Author PubWeight™ 154.87‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 High-throughput oncogene mutation profiling in human cancer. Nat Genet 2007 12.68
2 An integrated view of copy number and allelic alterations in the cancer genome using single nucleotide polymorphism arrays. Cancer Res 2004 8.86
3 Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysis. Cancer Res 2005 6.93
4 Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins. Cancer Res 2004 5.57
5 Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions. J Clin Invest 2009 5.07
6 Synthetic lethal screen identification of chemosensitizer loci in cancer cells. Nature 2007 4.70
7 Molecular profiling of breast cancer cell lines defines relevant tumor models and provides a resource for cancer gene discovery. PLoS One 2009 4.62
8 Aberrant epidermal growth factor receptor signaling and enhanced sensitivity to EGFR inhibitors in lung cancer. Cancer Res 2005 3.98
9 Interlaboratory comparability study of cancer gene expression analysis using oligonucleotide microarrays. Clin Cancer Res 2005 3.79
10 An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance. Clin Cancer Res 2012 3.48
11 Multiple oncogenic changes (K-RAS(V12), p53 knockdown, mutant EGFRs, p16 bypass, telomerase) are not sufficient to confer a full malignant phenotype on human bronchial epithelial cells. Cancer Res 2006 3.45
12 Distinct epidermal growth factor receptor and KRAS mutation patterns in non-small cell lung cancer patients with different tobacco exposure and clinicopathologic features. Clin Cancer Res 2006 3.40
13 Restoring E-cadherin expression increases sensitivity to epidermal growth factor receptor inhibitors in lung cancer cell lines. Cancer Res 2006 3.21
14 Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancer. Cancer Cell 2006 3.20
15 Activating mutations of the noonan syndrome-associated SHP2/PTPN11 gene in human solid tumors and adult acute myelogenous leukemia. Cancer Res 2004 3.20
16 PTEN loss contributes to erlotinib resistance in EGFR-mutant lung cancer by activation of Akt and EGFR. Cancer Res 2009 3.13
17 Expression of nicotinic acetylcholine receptor subunit genes in non-small-cell lung cancer reveals differences between smokers and nonsmokers. Cancer Res 2007 2.81
18 Alterations in genes of the EGFR signaling pathway and their relationship to EGFR tyrosine kinase inhibitor sensitivity in lung cancer cell lines. PLoS One 2009 2.79
19 Proteomic profiling identifies dysregulated pathways in small cell lung cancer and novel therapeutic targets including PARP1. Cancer Discov 2012 2.68
20 A genome-wide screen for promoter methylation in lung cancer identifies novel methylation markers for multiple malignancies. PLoS Med 2006 2.16
21 High resolution analysis of non-small cell lung cancer cell lines by whole genome tiling path array CGH. Int J Cancer 2006 2.16
22 Genome-scale analysis of DNA methylation in lung adenocarcinoma and integration with mRNA expression. Genome Res 2012 2.10
23 Lung cancer cell lines as tools for biomedical discovery and research. J Natl Cancer Inst 2010 1.92
24 An NQO1- and PARP-1-mediated cell death pathway induced in non-small-cell lung cancer cells by beta-lapachone. Proc Natl Acad Sci U S A 2007 1.92
25 Fine mapping of chromosome 6q23-25 region in familial lung cancer families reveals RGS17 as a likely candidate gene. Clin Cancer Res 2009 1.83
26 Knockdown of oncogenic KRAS in non-small cell lung cancers suppresses tumor growth and sensitizes tumor cells to targeted therapy. Mol Cancer Ther 2011 1.74
27 Sex determining region Y-Box 2 (SOX2) is a potential cell-lineage gene highly expressed in the pathogenesis of squamous cell carcinomas of the lung. PLoS One 2010 1.69
28 High-resolution single-nucleotide polymorphism array and clustering analysis of loss of heterozygosity in human lung cancer cell lines. Oncogene 2004 1.69
29 Paxillin is a target for somatic mutations in lung cancer: implications for cell growth and invasion. Cancer Res 2008 1.60
30 Robust gene expression signature from formalin-fixed paraffin-embedded samples predicts prognosis of non-small-cell lung cancer patients. Clin Cancer Res 2011 1.59
31 Non-small-cell lung cancers with kinase domain mutations in the epidermal growth factor receptor are sensitive to ionizing radiation. Cancer Res 2006 1.55
32 Comparing statistical methods for constructing large scale gene networks. PLoS One 2012 1.49
33 Breakdown of phonon glass paradigm in La- and Ce-filled Fe4Sb12 skutterudites. Nat Mater 2008 1.47
34 27-Hydroxycholesterol promotes cell-autonomous, ER-positive breast cancer growth. Cell Rep 2013 1.39
35 Ahi-1, a novel gene encoding a modular protein with WD40-repeat and SH3 domains, is targeted by the Ahi-1 and Mis-2 provirus integrations. J Virol 2002 1.38
36 A catalog of genes homozygously deleted in human lung cancer and the candidacy of PTPRD as a tumor suppressor gene. Genes Chromosomes Cancer 2010 1.33
37 Cytoglobin, the newest member of the globin family, functions as a tumor suppressor gene. Cancer Res 2008 1.28
38 STAT3 mediates resistance to MEK inhibitor through microRNA miR-17. Cancer Res 2011 1.24
39 Functional characterization of CLPTM1L as a lung cancer risk candidate gene in the 5p15.33 locus. PLoS One 2012 1.24
40 Increased expression of Cyr61 (CCN1) identified in peritoneal metastases from human pancreatic cancer. J Am Coll Surg 2005 1.23
41 Epidermal growth factor receptor pathway analysis identifies amphiregulin as a key factor for cisplatin resistance of human breast cancer cells. J Biol Chem 2007 1.20
42 The 3p21.3 tumor suppressor NPRL2 plays an important role in cisplatin-induced resistance in human non-small-cell lung cancer cells. Cancer Res 2006 1.19
43 Nuclear receptor expression defines a set of prognostic biomarkers for lung cancer. PLoS Med 2010 1.19
44 Steroid receptor coactivator-3 expression in lung cancer and its role in the regulation of cancer cell survival and proliferation. Cancer Res 2010 1.13
45 SMAC mimetic (JP1201) sensitizes non-small cell lung cancers to multiple chemotherapy agents in an IAP-dependent but TNF-α-independent manner. Cancer Res 2011 1.13
46 The SUMO E3-ligase PIAS1 regulates the tumor suppressor PML and its oncogenic counterpart PML-RARA. Cancer Res 2012 1.11
47 Methylation profiles of sporadic ovarian tumors and nonmalignant ovaries from high-risk women. Clin Cancer Res 2002 1.10
48 Tumor antigen acrosin binding protein normalizes mitotic spindle function to promote cancer cell proliferation. Cancer Res 2010 1.09
49 Oncogenic KRAS-induced interleukin-8 overexpression promotes cell growth and migration and contributes to aggressive phenotypes of non-small cell lung cancer. Int J Cancer 2011 1.08
50 Tumor mRNA expression profiles predict responses to chemotherapy. J Clin Oncol 2007 1.08
51 Gain of a region on 7p22.3, containing MAD1L1, is the most frequent event in small-cell lung cancer cell lines. Genes Chromosomes Cancer 2006 1.07
52 Frequent detection of infectious xenotropic murine leukemia virus (XMLV) in human cultures established from mouse xenografts. Cancer Biol Ther 2011 1.06
53 Distinct biological roles for the notch ligands Jagged-1 and Jagged-2. J Biol Chem 2009 1.06
54 Increased VEGFR-2 gene copy is associated with chemoresistance and shorter survival in patients with non-small-cell lung carcinoma who receive adjuvant chemotherapy. Cancer Res 2011 1.05
55 Increased expression and no mutation of the Flap endonuclease (FEN1) gene in human lung cancer. Oncogene 2003 1.03
56 Antitumor activity of a novel STAT3 inhibitor and redox modulator in non-small cell lung cancer cells. Biochem Pharmacol 2012 1.03
57 NeuroD1 regulates survival and migration of neuroendocrine lung carcinomas via signaling molecules TrkB and NCAM. Proc Natl Acad Sci U S A 2013 1.02
58 MicroRNA expression distinguishes SCLC from NSCLC lung tumor cells and suggests a possible pathological relationship between SCLCs and NSCLCs. J Exp Clin Cancer Res 2010 1.02
59 Global evaluation of Eph receptors and ephrins in lung adenocarcinomas identifies EphA4 as an inhibitor of cell migration and invasion. Mol Cancer Ther 2012 1.01
60 Research resource: Diagnostic and therapeutic potential of nuclear receptor expression in lung cancer. Mol Endocrinol 2012 1.01
61 MFSD2A is a novel lung tumor suppressor gene modulating cell cycle and matrix attachment. Mol Cancer 2010 0.96
62 Comprehensive biomarker analysis and final efficacy results of sorafenib in the BATTLE trial. Clin Cancer Res 2013 0.95
63 Establishment and expression profiling of new lung cancer cell lines from Chinese smokers and lifetime never-smokers. J Thorac Oncol 2006 0.92
64 Expression and methylation pattern of TSLC1 cascade genes in lung carcinomas. Oncogene 2006 0.91
65 Seizure 6-like (SEZ6L) gene and risk for lung cancer. Cancer Res 2007 0.91
66 Potential application of non-small cell lung cancer-associated autoantibodies to early cancer diagnosis. Biochem Biophys Res Commun 2012 0.90
67 Probe mapping across multiple microarray platforms. Brief Bioinform 2011 0.89
68 Cells lacking IKKα show nuclear cyclin D1 overexpression and a neoplastic phenotype: role of IKKα as a tumor suppressor. Mol Cancer Res 2011 0.88
69 Analysis of TP53 mutation status in human cancer cell lines: a reassessment. Hum Mutat 2014 0.86
70 Pivotal role of epithelial cell adhesion molecule in the survival of lung cancer cells. Cancer Sci 2011 0.85
71 Genes suppressed by DNA methylation in non-small cell lung cancer reveal the epigenetics of epithelial-mesenchymal transition. BMC Genomics 2014 0.85
72 Distinct transcriptome profiles identified in normal human bronchial epithelial cells after exposure to γ-rays and different elemental particles of high Z and energy. BMC Genomics 2013 0.85
73 Fragile histidine triad-mediated tumor suppression of lung cancer by targeting multiple components of the Ras/Rho GTPase molecular switch. Cancer Res 2007 0.85
74 ZEB1 drives epithelial-to-mesenchymal transition in lung cancer. J Clin Invest 2016 0.81
75 Radiation-enhanced lung cancer progression in a transgenic mouse model of lung cancer is predictive of outcomes in human lung and breast cancer. Clin Cancer Res 2014 0.79
76 TIMELESS is overexpressed in lung cancer and its expression correlates with poor patient survival. Cancer Sci 2013 0.77
77 Validation of SCT Methylation as a Hallmark Biomarker for Lung Cancers. J Thorac Oncol 2015 0.77
78 A reevaluation of CD22 expression in human lung cancer. Cancer Res 2014 0.75
79 Blasted cell line names. Cancer Inform 2010 0.75
80 Lyotropic lamellar phase formed from monolayered θ-shaped carborane-cage amphiphiles. Angew Chem Int Ed Engl 2013 0.75
81 Surface activity and molecular organization of metallacarboranes at the air-water interface revealed by nonlinear optics. Langmuir 2015 0.75