Published in Proteomics on May 01, 2010
Deconstructing the third dimension: how 3D culture microenvironments alter cellular cues. J Cell Sci (2012) 2.89
Designer matrices for intestinal stem cell and organoid culture. Nature (2016) 1.51
Growth-factor reduced Matrigel source influences stem cell derived brain microvascular endothelial cell barrier properties. Fluids Barriers CNS (2016) 1.40
Moving from static to dynamic complexity in hydrogel design. Nat Commun (2012) 1.40
3D biofabrication strategies for tissue engineering and regenerative medicine. Annu Rev Biomed Eng (2014) 1.12
A synthetic matrix with independently tunable biochemistry and mechanical properties to study epithelial morphogenesis and EMT in a lung adenocarcinoma model. Cancer Res (2012) 1.09
Use of collagen gel as an alternative extracellular matrix for the in vitro and in vivo growth of murine small intestinal epithelium. Tissue Eng Part C Methods (2013) 1.04
Liquid Crystalline Materials for Biological Applications. Chem Mater (2011) 1.02
Quantification of dynamic morphological drug responses in 3D organotypic cell cultures by automated image analysis. PLoS One (2014) 1.00
Matrix rigidity regulates cancer cell growth by modulating cellular metabolism and protein synthesis. PLoS One (2012) 0.99
Signals from the surface modulate differentiation of human pluripotent stem cells through glycosaminoglycans and integrins. Proc Natl Acad Sci U S A (2014) 0.95
Contractility of single cardiomyocytes differentiated from pluripotent stem cells depends on physiological shape and substrate stiffness. Proc Natl Acad Sci U S A (2015) 0.94
Type I collagen as an extracellular matrix for the in vitro growth of human small intestinal epithelium. PLoS One (2014) 0.94
Increased initiation and growth of tumor cell lines, cancer stem cells and biopsy material in mice using basement membrane matrix protein (Cultrex or Matrigel) co-injection. Nat Protoc (2012) 0.92
Src-dependent Tks5 phosphorylation regulates invadopodia-associated invasion in prostate cancer cells. Prostate (2013) 0.92
Overexpression and β-1,6-N-acetylglucosaminylation-initiated aberrant glycosylation of TIMP-1: a "double whammy" strategy in colon cancer progression. J Biol Chem (2012) 0.91
Human pluripotent stem cell-derived neural constructs for predicting neural toxicity. Proc Natl Acad Sci U S A (2015) 0.90
Comparison of the inhibitory activities of human tissue factor pathway inhibitor (TFPI)α and TFPIβ. J Thromb Haemost (2013) 0.90
Extracellular DNA in pancreatic cancer promotes cell invasion and metastasis. Cancer Res (2013) 0.90
TM4SF1: a new vascular therapeutic target in cancer. Angiogenesis (2014) 0.90
Gene expression profile of A549 cells from tissue of 4D model predicts poor prognosis in lung cancer patients. Int J Cancer (2013) 0.89
Transdifferentiation of alveolar epithelial type II to type I cells is controlled by opposing TGF-β and BMP signaling. Am J Physiol Lung Cell Mol Physiol (2013) 0.89
Experimental models of hepatotoxicity related to acute liver failure. Toxicol Appl Pharmacol (2015) 0.88
Differential effects of cell adhesion, modulus and VEGFR-2 inhibition on capillary network formation in synthetic hydrogel arrays. Biomaterials (2013) 0.88
Podosomes in space: macrophage migration and matrix degradation in 2D and 3D settings. Cell Adh Migr (2014) 0.88
Mass spectrometry-based proteomic analysis of the matrix microenvironment in pluripotent stem cell culture. Mol Cell Proteomics (2012) 0.88
Stepwise differentiation of pluripotent stem cells into osteoblasts using four small molecules under serum-free and feeder-free conditions. Stem Cell Reports (2014) 0.88
A 3D human neural cell culture system for modeling Alzheimer's disease. Nat Protoc (2015) 0.88
A peptide functionalized poly(ethylene glycol) (PEG) hydrogel for investigating the influence of biochemical and biophysical matrix properties on tumor cell migration. Biomater Sci (2014) 0.87
Defining synthetic surfaces for human pluripotent stem cell culture. Cell Regen (Lond) (2013) 0.87
A quantitative comparison of human HT-1080 fibrosarcoma cells and primary human dermal fibroblasts identifies a 3D migration mechanism with properties unique to the transformed phenotype. PLoS One (2013) 0.86
Proteomic analysis of naturally-sourced biological scaffolds. Biomaterials (2015) 0.86
A practical guide to hydrogels for cell culture. Nat Methods (2016) 0.86
An adipoinductive role of inflammation in adipose tissue engineering: key factors in the early development of engineered soft tissues. Stem Cells Dev (2013) 0.85
Peptide Hydrogels - Versatile Matrices for 3D Cell Culture in Cancer Medicine. Front Oncol (2015) 0.85
Facile engineering of xeno-free microcarriers for the scalable cultivation of human pluripotent stem cells in stirred suspension. Tissue Eng Part A (2013) 0.84
Formation of spatially and geometrically controlled three-dimensional tissues in soft gels by sacrificial micromolding. Tissue Eng Part C Methods (2014) 0.83
α-5 Laminin Synthesized by Human Pluripotent Stem Cells Promotes Self-Renewal. Stem Cell Reports (2015) 0.83
Biomaterial applications in cardiovascular tissue repair and regeneration. Expert Rev Cardiovasc Ther (2012) 0.83
A Cancer Cell Spheroid Assay to Assess Invasion in a 3D Setting. J Vis Exp (2015) 0.83
Stable engineered vascular networks from human induced pluripotent stem cell-derived endothelial cells cultured in synthetic hydrogels. Acta Biomater (2016) 0.83
Dynamic culture improves MSC adhesion on freeze-dried bone as a scaffold for bone engineering. World J Stem Cells (2012) 0.82
Maintenance of islet morphology is beneficial for transplantation outcome in diabetic mice. PLoS One (2013) 0.82
Engineering an in vitro air-blood barrier by 3D bioprinting. Sci Rep (2015) 0.81
Organotypic three-dimensional assays based on human leiomyoma-derived matrices. Philos Trans R Soc Lond B Biol Sci (2018) 0.81
β1 integrin signaling maintains human epithelial progenitor cell survival in situ and controls proliferation, apoptosis and migration of their progeny. PLoS One (2013) 0.81
Transactivation of the receptor-tyrosine kinase ephrin receptor A2 is required for the low molecular weight hyaluronan-mediated angiogenesis that is implicated in tumor progression. J Biol Chem (2014) 0.81
An engineered multicomponent bone marrow niche for the recapitulation of hematopoiesis at ectopic transplantation sites. J Hematol Oncol (2016) 0.80
Biomaterial Approaches for Stem Cell-Based Myocardial Tissue Engineering. Biomark Insights (2015) 0.80
"Strategic sequences" in adipose-derived stem cell nerve regeneration. Microsurgery (2013) 0.80
Characterization of Wnt/β-catenin and BMP/Smad signaling pathways in an in vitro model of amyotrophic lateral sclerosis. Front Cell Neurosci (2013) 0.80
Human iPSC-derived endothelial cell sprouting assay in synthetic hydrogel arrays. Acta Biomater (2016) 0.79
Proteome array identification of bioactive soluble proteins/peptides in Matrigel: relevance to stem cell responses. Cytotechnology (2014) 0.79
Differentiation of human embryonic stem cells to hepatocyte-like cells on a new developed xeno-free extracellular matrix. Histochem Cell Biol (2014) 0.79
Effects of cell-attachment and extracellular matrix on bone formation in vivo in collagen-hydroxyapatite scaffolds. PLoS One (2014) 0.79
An ortholog of the Leptospira interrogans lipoprotein LipL32 aids in the colonization of Pseudoalteromonas tunicata to host surfaces. Front Microbiol (2014) 0.79
Alzheimer's in 3D culture: challenges and perspectives. Bioessays (2015) 0.79
A novel human leiomyoma tissue derived matrix for cell culture studies. BMC Cancer (2015) 0.79
Molecular etching: a novel methodology for the generation of complex micropatterned growth surfaces for human cellular assays. Adv Healthc Mater (2014) 0.78
Small GTPase Rab21 mediates fibronectin induced actin reorganization in Entamoeba histolytica: implications in pathogen invasion. PLoS Pathog (2015) 0.78
Transporting Cells in Semi-Solid Gel Condition and at Ambient Temperature. PLoS One (2015) 0.78
Prostate cancer xenografts engineered from 3D precision-porous poly(2-hydroxyethyl methacrylate) hydrogels as models for tumorigenesis and dormancy escape. Biomaterials (2014) 0.78
Development of a simple, repeatable, and cost-effective extracellular matrix for long-term xeno-free and feeder-free self-renewal of human pluripotent stem cells. Histochem Cell Biol (2013) 0.78
Synthetic matrices reveal contributions of ECM biophysical and biochemical properties to epithelial morphogenesis. J Cell Biol (2015) 0.78
Dissecting the stem cell niche with organoid models: an engineering-based approach. Development (2017) 0.77
Basement membrane-rich organoids with functional human blood vessels are permissive niches for human breast cancer metastasis. PLoS One (2013) 0.77
Hematopoietic Stem and Progenitor Cell Expansion in Contact with Mesenchymal Stromal Cells in a Hanging Drop Model Uncovers Disadvantages of 3D Culture. Stem Cells Int (2015) 0.77
For whom the cells pull: Hydrogel and micropost devices for measuring traction forces. Methods (2015) 0.77
Application of tissue engineering to the immune system: development of artificial lymph nodes. Front Immunol (2012) 0.77
Biomodification of PCL Scaffolds with Matrigel, HA, and SR1 Enhances De Novo Ectopic Bone Marrow Formation Induced by rhBMP-2. Biores Open Access (2015) 0.77
In vitro 3D angiogenesis assay in egg white matrix: comparison to Matrigel, compatibility to various species, and suitability for drug testing. Lab Invest (2014) 0.77
Production of tissue-engineered intestine from expanded enteroids. J Surg Res (2016) 0.77
Simple insoluble cues specify stem cell differentiation. Proc Natl Acad Sci U S A (2014) 0.77
Going beyond compromises in multifunctionality of biomaterials. Adv Healthc Mater (2014) 0.77
GBM heterogeneity as a function of variable epidermal growth factor receptor variant III activity. Oncotarget (2016) 0.77
Biomaterial strategies for stem cell maintenance during in vitro expansion. Tissue Eng Part B Rev (2013) 0.76
Isolation and characterization of smooth muscle cells from rat corpus cavernosum tissue for the study of erectile dysfunction. Korean J Urol (2012) 0.76
Mammary fibroblasts regulate morphogenesis of normal and tumorigenic breast epithelial cells by mechanical and paracrine signals. Cancer Lett (2012) 0.76
Efficient generation of hPSC-derived midbrain dopaminergic neurons in a fully defined, scalable, 3D biomaterial platform. Sci Rep (2017) 0.76
Synthetic hydrogels mimicking basement membrane matrices to promote cell-matrix interactions. Matrix Biol (2016) 0.76
Versatile synthetic alternatives to Matrigel for vascular toxicity screening and stem cell expansion. Nat Biomed Eng (2017) 0.75
A Short Region of Connexin43 Reduces Human Glioma Stem Cell Migration, Invasion, and Survival through Src, PTEN, and FAK. Stem Cell Reports (2017) 0.75
Stiffened Extracellular Matrix and Signaling from Stromal Fibroblasts via Osteoprotegerin Regulate Tumor Cell Invasion in a 3-D Tumor in Situ Model. Cancer Microenviron (2016) 0.75
Culturing human intestinal stem cells for regenerative applications in the treatment of inflammatory bowel disease. EMBO Mol Med (2017) 0.75
Identification of polymer surface adsorbed proteins implicated in pluripotent human embryonic stem cell expansion. Biomater Sci (2016) 0.75
A microfluidics assay to study invasion of human placental trophoblast cells. J R Soc Interface (2017) 0.75
3D culture models of Alzheimer's disease: a road map to a "cure-in-a-dish". Mol Neurodegener (2016) 0.75
Long-Term Culture of Intestinal Cell Progenitors: An Overview of Their Development, Application, and Associated Technologies. Curr Pathobiol Rep (2016) 0.75
Development of glandular models from human nasal progenitor cells. Am J Respir Cell Mol Biol (2015) 0.75
The effects of self-assembling peptide RADA16 hydrogel on malignant phenotype of human hepatocellular carcinoma cell. Int J Clin Exp Med (2015) 0.75
Modular GAG-matrices to promote mammary epithelial morphogenesis in vitro. Biomaterials (2016) 0.75
The Influence of Platelet-Derived Growth Factor and Bone Morphogenetic Protein Presentation on Tubule Organization by Human Umbilical Vascular Endothelial Cells and Human Mesenchymal Stem Cells in Coculture. Tissue Eng Part A (2016) 0.75
The biophysical properties of Basal lamina gels depend on the biochemical composition of the gel. PLoS One (2015) 0.75
Recreating the Cardiac Microenvironment in Pluripotent Stem Cell Models of Human Physiology and Disease. Trends Cell Biol (2016) 0.75
Expanding Lipidome Coverage Using LC-MS/MS Data-Dependent Acquisition with Automated Exclusion List Generation. J Am Soc Mass Spectrom (2017) 0.75
Evaluation of fluorophore-tethered platinum complexes to monitor the fate of cisplatin analogs. J Biol Inorg Chem (2015) 0.75
The use of matrigel has no influence on tumor development or PET imaging in FaDu human head and neck cancer xenografts. BMC Med Imaging (2016) 0.75
A SILAC-Based Method for Quantitative Proteomic Analysis of Intestinal Organoids. Sci Rep (2016) 0.75
Human Organotypic Lung Tumor Models: Suitable For Preclinical 18F-FDG PET-Imaging. PLoS One (2016) 0.75
Preclinical activity of melflufen (J1) in ovarian cancer. Oncotarget (2016) 0.75
PEAKS DB: de novo sequencing assisted database search for sensitive and accurate peptide identification. Mol Cell Proteomics (2011) 2.37
Prevention of amino acid conversion in SILAC experiments with embryonic stem cells. Mol Cell Proteomics (2008) 1.83
Integrating structure, bioinformatics, and enzymology to discover function: BioH, a new carboxylesterase from Escherichia coli. J Biol Chem (2003) 1.61
Molecular characterization of staphyloferrin B biosynthesis in Staphylococcus aureus. Mol Microbiol (2009) 1.16
Characterization of staphyloferrin A biosynthetic and transport mutants in Staphylococcus aureus. Mol Microbiol (2009) 1.13
An enhanced mass spectrometry approach reveals human embryonic stem cell growth factors in culture. Mol Cell Proteomics (2008) 1.09
GPR54 (KISS1R) transactivates EGFR to promote breast cancer cell invasiveness. PLoS One (2011) 1.04
Formation of phosphopeptide-metal ion complexes in liquid chromatography/electrospray mass spectrometry and their influence on phosphopeptide detection. Rapid Commun Mass Spectrom (2005) 0.93
GlycoMaster DB: software to assist the automated identification of N-linked glycopeptides by tandem mass spectrometry. J Proteome Res (2014) 0.93
Proteomic analysis of extracellular matrices used in stem cell culture. Proteomics (2011) 0.91
Subunit disassembly and unfolding kinetics of hemoglobin studied by time-resolved electrospray mass spectrometry. Biochemistry (2004) 0.91
De novo sequencing methods in proteomics. Methods Mol Biol (2010) 0.89
Mass spectrometry-based proteomic analysis of the matrix microenvironment in pluripotent stem cell culture. Mol Cell Proteomics (2012) 0.88
Phosphorylation of Ser136 is critical for potent bone sialoprotein-mediated nucleation of hydroxyapatite crystals. Biochem J (2010) 0.86
An unbiased proteomic screen reveals caspase cleavage is positively and negatively regulated by substrate phosphorylation. Mol Cell Proteomics (2014) 0.84
Characterization of bovine surfactant proteins B and C by electrospray ionization mass spectrometry. Rapid Commun Mass Spectrom (2008) 0.83
Neuropeptide Y stimulates proliferation and migration in the 4T1 breast cancer cell line. Int J Cancer (2011) 0.82
Discovery and characterization of a nonphosphorylated cyclic peptide inhibitor of the peptidylprolyl isomerase, Pin1. J Med Chem (2011) 0.82
Photocontrol of nitric oxide production in cell culture using a caged isoform selective inhibitor. Bioorg Med Chem (2005) 0.81
On the catalysis of calcium oxalate dihydrate formation by osteopontin peptides. Colloids Surf B Biointerfaces (2012) 0.80
Selective sampling of phosphopeptides for detection by MALDI mass spectrometry. Anal Chem (2005) 0.80
Selective sampling of multiply phosphorylated peptides by capillary electrophoresis for electrospray ionization mass spectrometry analysis. J Chromatogr A (2006) 0.79
Photo-control of nitric oxide synthase activity using a caged isoform specific inhibitor. Bioorg Med Chem (2002) 0.78
Proteomics of human embryonic stem cells. Proteomics (2011) 0.78
An integrated procedure of selective injection, sample stacking and fractionation of phosphopeptides for MALDI MS analysis. Anal Chim Acta (2006) 0.78
A unique 3D in vitro cellular invasion assay. J Biomol Screen (2012) 0.77
Preparing titania aerogel monolithic chromatography columns using supercritical carbon dioxide. J Sep Sci (2010) 0.77
Synthesis and evaluation of trans 3,4-cyclopropyl L-arginine analogues as isoform selective inhibitors of nitric oxide synthase. Bioorg Med Chem (2003) 0.76
Investigation of calcium-binding proteins using electrospray ionization mass spectrometry. Methods Mol Biol (2002) 0.76
An Effective Approach for Glycan Structure De Novo Sequencing From HCD Spectra. IEEE Trans Nanobioscience (2016) 0.75
Synthesis of syn and anti isomers of trans-cyclopropyl arginine. J Org Chem (2002) 0.75