Jordi Barretina

Author PubWeight™ 164.91‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The landscape of somatic copy-number alteration across human cancers. Nature 2010 31.88
2 Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma. Proc Natl Acad Sci U S A 2007 18.83
3 COT drives resistance to RAF inhibition through MAP kinase pathway reactivation. Nature 2010 14.62
4 High-throughput oncogene mutation profiling in human cancer. Nat Genet 2007 12.68
5 Integrative analysis of the melanoma transcriptome. Genome Res 2010 8.46
6 Functional genomics reveal that the serine synthesis pathway is essential in breast cancer. Nature 2011 8.03
7 Melanoma genome sequencing reveals frequent PREX2 mutations. Nature 2012 7.77
8 The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer. Nat Genet 2009 6.99
9 CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity. Nature 2008 6.24
10 Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions. J Clin Invest 2009 5.07
11 Focal gains of VEGFA and molecular classification of hepatocellular carcinoma. Cancer Res 2008 4.35
12 Evidence that inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signaling. Cancer Cell 2009 4.30
13 Functional copy-number alterations in cancer. PLoS One 2008 4.27
14 Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer. Proc Natl Acad Sci U S A 2011 4.15
15 Amplification of chromosomal segment 4q12 in non-small cell lung cancer. Cancer Biol Ther 2009 2.47
16 Advances in sarcoma genomics and new therapeutic targets. Nat Rev Cancer 2011 2.34
17 An interactive resource to identify cancer genetic and lineage dependencies targeted by small molecules. Cell 2013 2.30
18 Nuclear factor I/B is an oncogene in small cell lung cancer. Genes Dev 2011 2.29
19 Gastrointestinal adenocarcinomas of the esophagus, stomach, and colon exhibit distinct patterns of genome instability and oncogenesis. Cancer Res 2012 2.26
20 CDYL bridges REST and histone methyltransferases for gene repression and suppression of cellular transformation. Mol Cell 2008 1.94
21 Global chromatin profiling reveals NSD2 mutations in pediatric acute lymphoblastic leukemia. Nat Genet 2013 1.77
22 High level of coreceptor-independent HIV transfer induced by contacts between primary CD4 T cells. J Biol Chem 2004 1.76
23 Wnt-pathway activation in two molecular classes of hepatocellular carcinoma and experimental modulation by sorafenib. Clin Cancer Res 2012 1.44
24 Genomic medicine frontier in human solid tumors: prospects and challenges. J Clin Oncol 2013 1.42
25 Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV-1 envelope. EMBO J 2002 1.42
26 R5 HIV gp120-mediated cellular contacts induce the death of single CCR5-expressing CD4 T cells by a gp41-dependent mechanism. J Leukoc Biol 2004 1.18
27 Strong expression of IGF1R in pediatric gastrointestinal stromal tumors without IGF1R genomic amplification. Int J Cancer 2010 1.08
28 Cell-surface-expressed HIV-1 envelope induces the death of CD4 T cells during GP41-mediated hemifusion-like events. Virology 2003 1.01
29 NF1 deletion generates multiple subtypes of soft-tissue sarcoma that respond to MEK inhibition. Mol Cancer Ther 2013 0.95
30 Reduced fitness of HIV-1 resistant to CXCR4 antagonists. Antivir Ther 2003 0.91
31 Preferential attachment of HIV particles to activated and CD45RO+CD4+ T cells. AIDS Res Hum Retroviruses 2002 0.91
32 Interleukin-7-dependent production of RANTES that correlates with human immunodeficiency virus disease progression. J Virol 2003 0.82
33 Anti-HIV activity of a novel aminoglycoside-arginine conjugate. Antiviral Res 2002 0.79