A de novo designed 11 kDa polypeptide: model for amyloidogenic intrinsically disordered proteins.

PubWeight™: 0.80‹?›

🔗 View Article (PMID 20162724)

Published in Biopolymers on July 01, 2010

Authors

Natalya I Topilina1, Vladimir V Ermolenkov, Vitali Sikirzhytski, Seiichiro Higashiya, Igor K Lednev, John T Welch

Author Affiliations

1: Department of Chemistry, State University of New York, Albany, NY 12222, USA.

Articles by these authors

Photonic crystal carbohydrate sensors: low ionic strength sugar sensing. J Am Chem Soc (2003) 1.42

High ionic strength glucose-sensing photonic crystal. Anal Chem (2003) 1.30

On the quenching of semiconductor quantum dot photoluminescence by proximal gold nanoparticles. Nano Lett (2007) 1.24

Analysis of body fluids for forensic purposes: from laboratory testing to non-destructive rapid confirmatory identification at a crime scene. Forensic Sci Int (2009) 1.13

The antituberculosis drug pyrazinamide affects the course of cutaneous leishmaniasis in vivo and increases activation of macrophages and dendritic cells. Antimicrob Agents Chemother (2009) 1.13

Mechanism of fibril formation by a 39-residue peptide (PAPf39) from human prostatic acidic phosphatase. Biochemistry (2009) 1.09

UV resonance Raman investigations of peptide and protein structure and dynamics. Chem Rev (2012) 1.08

2D correlation deep UV resonance raman spectroscopy of early events of lysozyme fibrillation: kinetic mechanism and potential interpretation pitfalls. J Am Chem Soc (2007) 1.07

Probing the cross-beta core structure of amyloid fibrils by hydrogen-deuterium exchange deep ultraviolet resonance Raman spectroscopy. J Am Chem Soc (2007) 1.04

Both Ca2+ and Zn2+ are essential for S100A12 protein oligomerization and function. BMC Biochem (2009) 1.03

Preparation and utility of organic pentafluorosulfanyl-containing compounds. Chem Rev (2014) 1.00

Comparison between UV Raman and circular dichroism detection of short alpha helices in bombolitin III. Biochemistry (2002) 0.99

Structure and composition of insulin fibril surfaces probed by TERS. J Am Chem Soc (2012) 0.99

Pyrazinoic acid and its n-propyl ester inhibit fatty acid synthase type I in replicating tubercle bacilli. Antimicrob Agents Chemother (2006) 0.98

Deep-UV Raman spectrometer tunable between 193 and 205 nm for structural characterization of proteins. Anal Bioanal Chem (2004) 0.97

Amide I vibrational mode suppression in surface (SERS) and tip (TERS) enhanced Raman spectra of protein specimens. Analyst (2013) 0.95

Potential application of Raman spectroscopy for determining burial duration of skeletal remains. Anal Bioanal Chem (2011) 0.95

Quantitative methods for structural characterization of proteins based on deep UV resonance Raman spectroscopy. Methods (2010) 0.94

Disulfide bridges remain intact while native insulin converts into amyloid fibrils. PLoS One (2012) 0.94

Spontaneous inter-conversion of insulin fibril chirality. Chem Commun (Camb) (2012) 0.93

Vibrational circular dichroism shows unusual sensitivity to protein fibril formation and development in solution. J Am Chem Soc (2007) 0.93

Raman spectroscopy of blood for species identification. Anal Chem (2014) 0.91

Normal and reversed supramolecular chirality of insulin fibrils probed by vibrational circular dichroism at the protofilament level of fibril structure. Biophys J (2012) 0.91

Amyloid fibrils are "alive": spontaneous refolding from one polymorph to another. Chem Commun (Camb) (2010) 0.91

Insight into resolution enhancement in generalized two-dimensional correlation spectroscopy. Appl Spectrosc (2013) 0.91

Probing a fibrillation nucleus directly by deep ultraviolet Raman spectroscopy. J Am Chem Soc (2007) 0.91

Inhibition of isolated Mycobacterium tuberculosis fatty acid synthase I by pyrazinamide analogs. Antimicrob Agents Chemother (2007) 0.90

Direct observation and pH control of reversed supramolecular chirality in insulin fibrils by vibrational circular dichroism. Chem Commun (Camb) (2010) 0.90

Raman spectroscopy offers great potential for the nondestructive confirmatory identification of body fluids. Forensic Sci Int (2008) 0.89

Pathogenic serum amyloid A 1.1 shows a long oligomer-rich fibrillation lag phase contrary to the highly amyloidogenic non-pathogenic SAA2.2. J Biol Chem (2012) 0.89

Structural variations in the cross-beta core of amyloid beta fibrils revealed by deep UV resonance Raman spectroscopy. J Am Chem Soc (2010) 0.88

Raman spectroscopic signature of blood and its potential application to forensic body fluid identification. Anal Bioanal Chem (2009) 0.88

Dissecting structure of prion amyloid fibrils by hydrogen-deuterium exchange ultraviolet Raman spectroscopy. J Phys Chem B (2012) 0.87

Hen egg white lysozyme fibrillation: a deep-UV resonance Raman spectroscopic study. J Biophotonics (2008) 0.87

Lysozyme fibrillation: deep UV Raman spectroscopic characterization of protein structural transformation. Biopolymers (2005) 0.86

Genetic engineering combined with deep UV resonance Raman spectroscopy for structural characterization of amyloid-like fibrils. J Am Chem Soc (2008) 0.86

Mutually exclusive genotypes for pyrazinamide and 5-chloropyrazinamide resistance reveal a potential resistance-proofing strategy. Antimicrob Agents Chemother (2010) 0.85

Design and preparation of beta-sheet forming repetitive and block-copolymerized polypeptides. Biomacromolecules (2007) 0.84

Discriminant analysis of Raman spectra for body fluid identification for forensic purposes. Sensors (Basel) (2010) 0.84

Isolating toxic insulin amyloid reactive species that lack β-sheets and have wide pH stability. Biophys J (2011) 0.83

Bilayer fibril formation by genetically engineered polypeptides: preparation and characterization. Biomacromolecules (2006) 0.83

Blood species identification for forensic purposes using Raman spectroscopy combined with advanced statistical analysis. Anal Chem (2009) 0.83

Electrolytic Partial Fluorination of Organic Compounds. 32.(1) Regioselective Anodic Mono- and Difluorination of Flavones. J Org Chem (1999) 0.82

UVRR spectroscopic studies of valinomycin complex formation in different solvents. Spectrochim Acta A Mol Biomol Spectrosc (2005) 0.81

Inhibition of dipeptidyl peptidase IV (DPP IV) by 2-(2-amino-1-fluoro-propylidene)-cyclopentanecarbonitrile, a fluoroolefin containing peptidomimetic. Bioorg Med Chem (2003) 0.81

The first step of hen egg white lysozyme fibrillation, irreversible partial unfolding, is a two-state transition. Protein Sci (2007) 0.81

Advanced statistical and numerical methods for spectroscopic characterization of protein structural evolution. Chem Rev (2010) 0.81

Acidic pH promotes oligomerization and membrane insertion of the BclXL apoptotic repressor. Arch Biochem Biophys (2012) 0.81

Levels of supramolecular chirality of polyglutamine aggregates revealed by vibrational circular dichroism. FEBS Lett (2013) 0.81

Is supramolecular filament chirality the underlying cause of major morphology differences in amyloid fibrils? J Am Chem Soc (2014) 0.80

Charge distribution and amyloid fibril formation: insights from genetically engineered model systems. Biomacromolecules (2010) 0.80

Activity of 5-chloro-pyrazinamide in mice infected with Mycobacterium tuberculosis or Mycobacterium bovis. Indian J Med Res (2012) 0.79

Deconstruction of stable cross-Beta fibrillar structures into toxic and nontoxic products using a mutated archaeal chaperonin. ACS Chem Biol (2013) 0.79

Fibrillation mechanism of a model intrinsically disordered protein revealed by 2D correlation deep UV resonance Raman spectroscopy. Biomacromolecules (2012) 0.79

Forensic body fluid identification: the Raman spectroscopic signature of saliva. Analyst (2009) 0.79

Reversible thermal denaturation of a 60-kDa genetically engineered beta-sheet polypeptide. Biophys J (2006) 0.79

Sirtuin 6: a review of biological effects and potential therapeutic properties. Mol Biosyst (2013) 0.79

Raman spectroscopy coupled with advanced statistics for differentiating menstrual and peripheral blood. J Biophotonics (2012) 0.79

Exploring the structure and formation mechanism of amyloid fibrils by Raman spectroscopy: a review. Analyst (2015) 0.79

Multidimensional Raman spectroscopic signatures as a tool for forensic identification of body fluid traces: a review. Appl Spectrosc (2011) 0.79

Vibrational spectroscopy: recent developments to revolutionize forensic science. Anal Chem (2014) 0.79

Rapid degradation kinetics of amyloid fibrils under mild conditions by an archaeal chaperonin. Biochem Biophys Res Commun (2012) 0.78

Raman spectroscopic analysis of gunshot residue offering great potential for caliber differentiation. Anal Chem (2012) 0.78

Multiple bicyclic diamide-lutetium complexes in solution: chemometric analysis of deep-UV Raman spectroscopic data. Inorg Chem (2006) 0.78

Designer variable repeat length polypeptides as scaffolds for surface immobilization of quantum dots. J Phys Chem B (2006) 0.78

Attenuated total reflectance-FT-IR imaging for rapid and automated detection of gunshot residue. Anal Chem (2014) 0.78

Attenuated total reflectance-FT-IR spectroscopy for gunshot residue analysis: potential for ammunition determination. Anal Chem (2013) 0.78

Raman spectroscopic signature of vaginal fluid and its potential application in forensic body fluid identification. Forensic Sci Int (2011) 0.77

Raman spectroscopic signature of semen and its potential application to forensic body fluid identification. Forensic Sci Int (2009) 0.77

Multidimensional Raman spectroscopic signature of sweat and its potential application to forensic body fluid identification. Anal Chim Acta (2012) 0.76

Raman spectroscopic study of the tautomeric composition of adenine in water. J Phys Chem A (2011) 0.76

Pyrazinamide, but not pyrazinoic acid, is a competitive inhibitor of NADPH binding to Mycobacterium tuberculosis fatty acid synthase I. Bioorg Med Chem Lett (2011) 0.76

Structural landscape of the proline-rich domain of Sos1 nucleotide exchange factor. Biophys Chem (2013) 0.76

Heat-induced fibrillation of BclXL apoptotic repressor. Biophys Chem (2013) 0.76

Beta-sheet folding of 11-kDa fibrillogenic polypeptide is completely aggregation driven. Biopolymers (2007) 0.76