David Arnott

Author PubWeight™ 45.96‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The ubiquitin ligase COP1 is a critical negative regulator of p53. Nature 2004 5.05
2 DUBA: a deubiquitinase that regulates type I interferon production. Science 2007 3.88
3 Human De-etiolated-1 regulates c-Jun by assembling a CUL4A ubiquitin ligase. Science 2004 3.28
4 Automated de novo protein sequencing of monoclonal antibodies. Nat Biotechnol 2008 3.02
5 Association of C-terminal ubiquitin hydrolase BRCA1-associated protein 1 with cell cycle regulator host cell factor 1. Mol Cell Biol 2009 2.26
6 Autophosphorylated CaMKIIalpha acts as a scaffold to recruit proteasomes to dendritic spines. Cell 2010 2.02
7 Ubiquitin binding modulates IAP antagonist-stimulated proteasomal degradation of c-IAP1 and c-IAP2(1). Biochem J 2009 1.94
8 Phosphorylation of NLRC4 is critical for inflammasome activation. Nature 2012 1.92
9 COP1 is a tumour suppressor that causes degradation of ETS transcription factors. Nature 2011 1.83
10 Improved quantitative mass spectrometry methods for characterizing complex ubiquitin signals. Mol Cell Proteomics 2010 1.43
11 Phosphorylation-dependent activity of the deubiquitinase DUBA. Nat Struct Mol Biol 2012 1.42
12 Ubiquitin binding to A20 ZnF4 is required for modulation of NF-κB signaling. Mol Cell 2010 1.41
13 Targeted mass spectrometric strategy for global mapping of ubiquitination on proteins. Rapid Commun Mass Spectrom 2007 1.21
14 Death-receptor activation halts clathrin-dependent endocytosis. Proc Natl Acad Sci U S A 2006 1.18
15 De novo proteomic sequencing of a monoclonal antibody raised against OX40 ligand. Anal Biochem 2006 1.12
16 Glycan shifting on hepatitis C virus (HCV) E2 glycoprotein is a mechanism for escape from broadly neutralizing antibodies. J Mol Biol 2013 1.11
17 OTUB1 modulates c-IAP1 stability to regulate signalling pathways. EMBO J 2013 1.09
18 Resurrection of a clinical antibody: template proteogenomic de novo proteomic sequencing and reverse engineering of an anti-lymphotoxin-α antibody. Proteomics 2011 1.08
19 B and T lymphocyte attenuator regulates B cell receptor signaling by targeting Syk and BLNK. J Immunol 2009 1.08
20 Mass spectrometric contributions to the practice of phosphorylation site mapping through 2003: a literature review. Mol Cell Proteomics 2005 1.05
21 Template proteogenomics: sequencing whole proteins using an imperfect database. Mol Cell Proteomics 2010 1.04
22 Furin-cleaved proprotein convertase subtilisin/kexin type 9 (PCSK9) is active and modulates low density lipoprotein receptor and serum cholesterol levels. J Biol Chem 2012 0.99
23 Identification of longitudinally dynamic biomarkers in Alzheimer's disease cerebrospinal fluid by targeted proteomics. Mol Neurodegener 2014 0.93
24 Bioinformatics analysis of thousands of TCGA tumors to determine the involvement of epigenetic regulators in human cancer. BMC Genomics 2015 0.88
25 Identifying potential therapeutic targets of methicillin-resistant Staphylococcus aureus through in vivo proteomic analysis. J Infect Dis 2013 0.85
26 Proteome analysis of antibody-producing CHO cell lines with different metabolic profiles. Biotechnol Bioeng 2007 0.84
27 Ubiquilin4 is an adaptor protein that recruits Ubiquilin1 to the autophagy machinery. EMBO Rep 2013 0.84
28 Targeting interferon alpha subtypes in serum: a comparison of analytical approaches to the detection and quantitation of proteins in complex biological matrices. J Proteome Res 2009 0.81
29 Proteomics. Methods Enzymol 2005 0.80
30 Disulfide locked variants of factor VIIa with a restricted beta-strand conformation have enhanced enzymatic activity. Protein Sci 2005 0.80