PubRank

Anil K Rustgi

Author PubWeight™ 213.78‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The landscape of somatic copy-number alteration across human cancers. Nature 2010 31.88
2 Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice. Cancer Cell 2005 14.21
3 EMT and dissemination precede pancreatic tumor formation. Cell 2012 9.27
4 SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas. Nat Genet 2009 7.48
5 Esophageal carcinoma. N Engl J Med 2014 5.77
6 Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer. Proc Natl Acad Sci U S A 2008 4.79
7 Pancreatic cancer: novel approaches to diagnosis and therapy. Gastroenterology 2005 4.06
8 Pancreatic epithelial plasticity mediated by acinar cell transdifferentiation and generation of nestin-positive intermediates. Development 2005 3.57
9 A combined syndrome of juvenile polyposis and hereditary haemorrhagic telangiectasia associated with mutations in MADH4 (SMAD4). Lancet 2004 2.97
10 Identification of Lynch syndrome among patients with colorectal cancer. JAMA 2012 2.77
11 Treatment and prevention of intraepithelial neoplasia: an important target for accelerated new agent development. Clin Cancer Res 2002 2.71
12 Epidermal growth factor receptor mediates increased cell proliferation, migration, and aggregation in esophageal keratinocytes in vitro and in vivo. J Biol Chem 2002 2.58
13 Common activation of canonical Wnt signaling in pancreatic adenocarcinoma. PLoS One 2007 2.26
14 Bile acid and inflammation activate gastric cardia stem cells in a mouse model of Barrett-like metaplasia. Cancer Cell 2012 2.16
15 The functional interplay between EGFR overexpression, hTERT activation, and p53 mutation in esophageal epithelial cells with activation of stromal fibroblasts induces tumor development, invasion, and differentiation. Genes Dev 2007 2.16
16 Telomerase induces immortalization of human esophageal keratinocytes without p16INK4a inactivation. Mol Cancer Res 2003 2.12
17 Successful growth and characterization of mouse pancreatic ductal cells: functional properties of the Ki-RAS(G12V) oncogene. Gastroenterology 2004 2.11
18 Deletion of p120-catenin results in a tumor microenvironment with inflammation and cancer that establishes it as a tumor suppressor gene. Cancer Cell 2011 2.10
19 LIN28B promotes colon cancer progression and metastasis. Cancer Res 2011 2.05
20 Detection of proximal adenomatous polyps with screening sigmoidoscopy: a systematic review and meta-analysis of screening colonoscopy. Arch Intern Med 2003 2.02
21 Recurrence of esophageal intestinal metaplasia after endoscopic mucosal resection and radiofrequency ablation of Barrett's esophagus: results from a US Multicenter Consortium. Gastroenterology 2013 1.92
22 The mutant K-ras oncogene causes pancreatic periductal lymphocytic infiltration and gastric mucous neck cell hyperplasia in transgenic mice. Cancer Res 2003 1.89
23 The role of the miR-200 family in epithelial-mesenchymal transition. Cancer Biol Ther 2010 1.89
24 Imbalance of desmoplastic stromal cell numbers drives aggressive cancer processes. J Pathol 2013 1.86
25 The hereditary nonpolyposis colorectal cancer syndrome: genetics and clinical implications. Ann Intern Med 2003 1.84
26 Pancreatic ductal cells in development, regeneration, and neoplasia. J Clin Invest 2011 1.80
27 Mutations in Fbx4 inhibit dimerization of the SCF(Fbx4) ligase and contribute to cyclin D1 overexpression in human cancer. Cancer Cell 2008 1.78
28 Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase. Cancer Cell 2010 1.76
29 Detecting and targeting mesenchymal-like subpopulations within squamous cell carcinomas. Cell Cycle 2011 1.70
30 A subpopulation of mouse esophageal basal cells has properties of stem cells with the capacity for self-renewal and lineage specification. J Clin Invest 2008 1.69
31 Nuclear accumulation of cyclin D1 during S phase inhibits Cul4-dependent Cdt1 proteolysis and triggers p53-dependent DNA rereplication. Genes Dev 2007 1.65
32 Cell cycle dependent and schedule-dependent antitumor effects of sorafenib combined with radiation. Cancer Res 2007 1.58
33 Periostin, a cell adhesion molecule, facilitates invasion in the tumor microenvironment and annotates a novel tumor-invasive signature in esophageal cancer. Cancer Res 2010 1.58
34 Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers. PLoS One 2011 1.57
35 Clinical trial resources on the internet must be designed to reach underrepresented minorities. Cancer J 2007 1.56
36 The diabetes gene Pdx1 regulates the transcriptional network of pancreatic endocrine progenitor cells in mice. J Clin Invest 2009 1.54
37 Mutant KRAS in the initiation of pancreatic cancer. Biochim Biophys Acta 2005 1.54
38 Epidermal growth factor receptor and mutant p53 expand an esophageal cellular subpopulation capable of epithelial-to-mesenchymal transition through ZEB transcription factors. Cancer Res 2010 1.52
39 Isolation and characterization of mouse and human esophageal epithelial cells in 3D organotypic culture. Nat Protoc 2012 1.51
40 Colon cancer screening practices following genetic testing for hereditary nonpolyposis colon cancer (HNPCC) mutations. Arch Intern Med 2004 1.48
41 Notch1 functions as a tumor suppressor in a model of K-ras-induced pancreatic ductal adenocarcinoma. Cancer Res 2010 1.45
42 Cleavage of MCM2 licensing protein fosters senescence in human keratinocytes. Cell Cycle 2008 1.42
43 A mouse model of human oral-esophageal cancer. J Clin Invest 2002 1.40
44 Fibroblast-secreted hepatocyte growth factor plays a functional role in esophageal squamous cell carcinoma invasion. Proc Natl Acad Sci U S A 2010 1.37
45 Cdx1 and c-Myc foster the initiation of transdifferentiation of the normal esophageal squamous epithelium toward Barrett's esophagus. PLoS One 2008 1.34
46 Death induction by recombinant native TRAIL and its prevention by a caspase 9 inhibitor in primary human esophageal epithelial cells. J Biol Chem 2004 1.29
47 Cyclin D1 induction through IkappaB kinase beta/nuclear factor-kappaB pathway is responsible for arsenite-induced increased cell cycle G1-S phase transition in human keratinocytes. Cancer Res 2005 1.28
48 The Prrx1 homeodomain transcription factor plays a central role in pancreatic regeneration and carcinogenesis. Genes Dev 2013 1.28
49 Pancreatic cancer in mice and man: the Penn Workshop 2004. Cancer Res 2006 1.24
50 Characterization of proteins in human pancreatic cancer serum using differential gel electrophoresis and tandem mass spectrometry. J Proteome Res 2005 1.24
51 LIN28B promotes growth and tumorigenesis of the intestinal epithelium via Let-7. Genes Dev 2013 1.23
52 EGFR-induced cell migration is mediated predominantly by the JAK-STAT pathway in primary esophageal keratinocytes. Am J Physiol Gastrointest Liver Physiol 2004 1.20
53 Tumorigenic conversion of primary human esophageal epithelial cells using oncogene combinations in the absence of exogenous Ras. Cancer Res 2006 1.20
54 Stable isotope dilution multidimensional liquid chromatography-tandem mass spectrometry for pancreatic cancer serum biomarker discovery. J Proteome Res 2009 1.18
55 SOX2 and p63 colocalize at genetic loci in squamous cell carcinomas. J Clin Invest 2014 1.10
56 Wnt-1 but not epidermal growth factor induces beta-catenin/T-cell factor-dependent transcription in esophageal cancer cells. Cancer Res 2002 1.10
57 Adult pancreatic acinar cells dedifferentiate to an embryonic progenitor phenotype with concomitant activation of a senescence programme that is present in chronic pancreatitis. Gut 2010 1.09
58 Pancreatic ductal morphogenesis and the Pdx1 homeodomain transcription factor. Mol Biol Cell 2009 1.09
59 IMP-1 displays cross-talk with K-Ras and modulates colon cancer cell survival through the novel proapoptotic protein CYFIP2. Cancer Res 2011 1.07
60 N-cadherin and keratinocyte growth factor receptor mediate the functional interplay between Ki-RASG12V and p53V143A in promoting pancreatic cell migration, invasion, and tissue architecture disruption. Mol Cell Biol 2006 1.06
61 Creating oral squamous cancer cells: a cellular model of oral-esophageal carcinogenesis. Proc Natl Acad Sci U S A 2005 1.05
62 Activation of a nuclear Cdc2-related kinase within a mitogen-activated protein kinase-like TDY motif by autophosphorylation and cyclin-dependent protein kinase-activating kinase. Mol Cell Biol 2005 1.04
63 The PDX1 homeodomain transcription factor negatively regulates the pancreatic ductal cell-specific keratin 19 promoter. J Biol Chem 2006 1.04
64 Identification of a bone marrow-derived mesenchymal progenitor cell subset that can contribute to the gastric epithelium. Lab Invest 2009 1.03
65 K-ras mutation targeted to gastric tissue progenitor cells results in chronic inflammation, an altered microenvironment, and progression to intraepithelial neoplasia. Cancer Res 2010 1.02
66 Isoform-specific upregulation of palladin in human and murine pancreas tumors. PLoS One 2010 1.01
67 SILAC-based quantitative proteomic approach to identify potential biomarkers from the esophageal squamous cell carcinoma secretome. Cancer Biol Ther 2010 1.00
68 No one-way street: cross-talk between e-cadherin and receptor tyrosine kinase (RTK) signaling: a mechanism to regulate RTK activity. Cancer Biol Ther 2005 0.99
69 Constitutive K-RasG12D activation of ERK2 specifically regulates 3D invasion of human pancreatic cancer cells via MMP-1. Mol Cancer Res 2011 0.98
70 Cathepsin B is the driving force of esophageal cell invasion in a fibroblast-dependent manner. Neoplasia 2010 0.98
71 Genetic alterations in esophageal cancer. Methods Mol Biol 2003 0.97
72 Isolation, culture and genetic manipulation of mouse pancreatic ductal cells. Nat Protoc 2013 0.97
73 Bortezomib induces apoptosis in esophageal squamous cell carcinoma cells through activation of the p38 mitogen-activated protein kinase pathway. Mol Cancer Ther 2008 0.96
74 Induction of intestinalization in human esophageal keratinocytes is a multistep process. Carcinogenesis 2008 0.96
75 Differential secreted proteome approach in murine model for candidate biomarker discovery in colon cancer. J Proteome Res 2009 0.96
76 PRR5 encodes a conserved proline-rich protein predominant in kidney: analysis of genomic organization, expression, and mutation status in breast and colorectal carcinomas. Genomics 2005 0.96
77 Beta-parvin inhibits integrin-linked kinase signaling and is downregulated in breast cancer. Oncogene 2004 0.95
78 Coordinated functions of E-cadherin and transforming growth factor beta receptor II in vitro and in vivo. Cancer Res 2006 0.95
79 Myeloid derived suppressor cells: Targets for therapy. Oncoimmunology 2013 0.94
80 The Fbx4 tumor suppressor regulates cyclin D1 accumulation and prevents neoplastic transformation. Mol Cell Biol 2011 0.94
81 Local hypersensitivity reaction in transgenic mice with squamous epithelial IL-5 overexpression provides a novel model of eosinophilic oesophagitis. Gut 2012 0.94
82 Parvin-beta inhibits breast cancer tumorigenicity and promotes CDK9-mediated peroxisome proliferator-activated receptor gamma 1 phosphorylation. Mol Cell Biol 2007 0.94
83 Barrett's esophagus and its progression to adenocarcinoma. J Natl Compr Canc Netw 2006 0.93
84 Epigenetic silencing of CDX2 is a feature of squamous esophageal cancer. Int J Cancer 2007 0.93
85 Preexisting oncogenic events impact trastuzumab sensitivity in ERBB2-amplified gastroesophageal adenocarcinoma. J Clin Invest 2014 0.92
86 IMP1 promotes tumor growth, dissemination and a tumor-initiating cell phenotype in colorectal cancer cell xenografts. Carcinogenesis 2013 0.92
87 Optical imaging of periostin enables early endoscopic detection and characterization of esophageal cancer in mice. Gastroenterology 2012 0.91
88 Cyclin D1 overexpression increases susceptibility to 4-nitroquinoline-1-oxide-induced dysplasia and neoplasia in murine squamous oral epithelium. Mol Carcinog 2009 0.91
89 ARHGAP8 is a novel member of the RHOGAP family related to ARHGAP1/CDC42GAP/p50RHOGAP: mutation and expression analyses in colorectal and breast cancers. Gene 2004 0.90
90 Systemic activation of K-ras rapidly induces gastric hyperplasia and metaplasia in mice. Am J Cancer Res 2011 0.87
91 Triggering ubiquitination of IFNAR1 protects tissues from inflammatory injury. EMBO Mol Med 2014 0.87
92 The pancreatic and duodenal homeobox protein PDX-1 regulates the ductal specific keratin 19 through the degradation of MEIS1 and DNA binding. PLoS One 2010 0.87
93 Dexamethasone treatment induces the reprogramming of pancreatic acinar cells to hepatocytes and ductal cells. PLoS One 2010 0.87
94 EGFR inhibition promotes an aggressive invasion pattern mediated by mesenchymal-like tumor cells within squamous cell carcinomas. Mol Cancer Ther 2013 0.86
95 Comparative secretome analysis of epithelial and mesenchymal subpopulations of head and neck squamous cell carcinoma identifies S100A4 as a potential therapeutic target. Mol Cell Proteomics 2013 0.85
96 Combined cyclin D1 overexpression and zinc deficiency disrupts cell cycle and accelerates mouse forestomach carcinogenesis. Cancer Res 2003 0.85
97 Evaluation of PARVG located on 22q13 as a candidate tumor suppressor gene for colorectal and breast cancer. Cancer Genet Cytogenet 2003 0.84
98 Modeling inflammation and oxidative stress in gastrointestinal disease development using novel organotypic culture systems. Stem Cell Res Ther 2013 0.83
99 Pancreatic cancer: translating lessons from mouse models and hereditary syndromes. Cancer Prev Res (Phila) 2008 0.83
100 Inhibition of Notch signaling enhances transdifferentiation of the esophageal squamous epithelium towards a Barrett's-like metaplasia via KLF4. Cell Cycle 2014 0.83
101 A LIN28B polymorphism predicts for colon cancer survival. Cancer Biol Ther 2012 0.82
102 Securin a new role for itself. Nat Genet 2002 0.82
103 Colon cancer: an update and future directions. Gastroenterology 2010 0.82
104 Silencing of IkBβ mRNA causes disruption of mitochondrial retrograde signaling and suppression of tumor growth in vivo. Carcinogenesis 2012 0.81
105 Low frequency of MLL3 mutations in colorectal carcinoma. Cancer Genet Cytogenet 2009 0.81
106 Advanced imaging and technology in gastrointestinal neoplasia: summary of the AGA-NCI Symposium October 4-5, 2004. Gastroenterology 2006 0.80
107 Conflicts of interest and disclosures in publications. Clin Gastroenterol Hepatol 2007 0.80
108 O-GlcNAc transferase is critical for transducin-like enhancer of split (TLE)-mediated repression of canonical Wnt signaling. J Biol Chem 2014 0.80
109 Endothelin-3 stimulates survival of goblet cells in organotypic cultures of fetal human colonic epithelium. Am J Physiol Gastrointest Liver Physiol 2008 0.80
110 Development and characterization of an organotypic model of Barrett's esophagus. J Cell Physiol 2012 0.80
111 Alternative splicing of the APC gene in the neural retina and retinal pigment epithelium. Mol Vis 2004 0.79
112 Tobacco-specific carcinogen nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induces AKT activation in head and neck epithelia. Int J Oncol 2011 0.79
113 ERK2-regulated TIMP1 induces hyperproliferation of K-Ras(G12D)-transformed pancreatic ductal cells. Neoplasia 2013 0.79
114 Advances in acute and chronic pancreatitis: from development to inflammation and repair. Gastroenterology 2012 0.78
115 Ionizing radiation enhances esophageal epithelial cell migration and invasion through a paracrine mechanism involving stromal-derived hepatocyte growth factor. Radiat Res 2011 0.78
116 Fluorescent nanoparticle imaging allows noninvasive evaluation of immune cell modulation in esophageal dysplasia. Mol Imaging 2014 0.78
117 Breaking the barriers to colorectal cancer screening. Gastroenterology 2004 0.77
118 FBXO4 loss facilitates carcinogen induced papilloma development in mice. Cancer Biol Ther 2015 0.76
119 Journal’s withdrawal of article. Gastroenterology study not withdrawn from publication. BMJ 2011 0.75
120 Amyloid fiber formation in E. coli. Gastroenterology 2002 0.75
121 Gastroenterology year in review. Gastroenterology 2009 0.75
122 Senate amendment aims to hike NIH funding. Gastroenterology 2003 0.75
123 AGA program at DDW--a success. Gastroenterology 2002 0.75
124 Minutes of the Business Meeting of the American Pancreatic Association, Friday, October 28, 2016, Boston, Massachusetts. Pancreas 2017 0.75
125 Gastroenterology 2007 in review. Gastroenterology 2008 0.75
126 Erratum: Lkb1 inactivation drives lung cancer lineage switching governed by Polycomb Repressive Complex 2. Nat Commun 2017 0.75
127 Gastroenterology: a year of growth and change. Gastroenterology 2010 0.75
128 NIDDK names IBD expert digestive diseases director. Gastroenterology 2004 0.75
129 Hepatitis B "X" gene linked to cellular calcium release. Gastroenterology 2002 0.75
130 Advances and challenges in aerodigestive epithelial cancer: meeting summary and research opportunities. Cancer Res 2007 0.75
131 Gastroenterology's editors-in-chief: historical and personal perspectives of their editorships. Gastroenterology 2013 0.75