Published in Mol Nutr Food Res on April 01, 2010
Sulforaphane as a potential protective phytochemical against neurodegenerative diseases. Oxid Med Cell Longev (2013) 1.03
Brain mitochondria from rats treated with sulforaphane are resistant to redox-regulated permeability transition. J Bioenerg Biomembr (2010) 0.91
Neuroprotection by spice-derived nutraceuticals: you are what you eat! Mol Neurobiol (2011) 0.90
Dietary antiaging phytochemicals and mechanisms associated with prolonged survival. J Nutr Biochem (2014) 0.88
Attenuation of β-amyloid-induced oxidative cell death by sulforaphane via activation of NF-E2-related factor 2. Oxid Med Cell Longev (2013) 0.86
Dimethyl Fumarate Protects Neural Stem/Progenitor Cells and Neurons from Oxidative Damage through Nrf2-ERK1/2 MAPK Pathway. Int J Mol Sci (2015) 0.86
Cellular stress response, sirtuins and UCP proteins in Alzheimer disease: role of vitagenes. Immun Ageing (2013) 0.85
Isothiocyanates Are Promising Compounds against Oxidative Stress, Neuroinflammation and Cell Death that May Benefit Neurodegeneration in Parkinson's Disease. Int J Mol Sci (2016) 0.79
Downregulation of thioredoxin reductase 1 expression in the substantia nigra pars compacta of Parkinson's disease mice. Neural Regen Res (2013) 0.77
The Role of Glucosinolate Hydrolysis Products from Brassica Vegetable Consumption in Inducing Antioxidant Activity and Reducing Cancer Incidence. Diseases (2016) 0.76
Antiglycative activity of sulforaphane: a new avenue to counteract neurodegeneration? Neural Regen Res (2015) 0.75
Suppression in PHLPP2 induction by morin promotes Nrf2-regulated cellular defenses against oxidative injury to primary rat hepatocytes. Redox Biol (2015) 0.75
Assessing competence of broccoli consumption on inflammatory and antioxidant pathways in restraint-induced models: estimation in rat hippocampus and prefrontal cortex. Biomed Res Int (2013) 0.75
DNA Microarray Highlights Nrf2-Mediated Neuron Protection Targeted by Wasabi-Derived Isothiocyanates in IMR-32 Cells. Gene Regul Syst Bio (2016) 0.75
Flavonoids: antioxidants or signalling molecules? Free Radic Biol Med (2004) 3.76
The E3 ligase parkin maintains mitochondrial integrity by increasing linear ubiquitination of NEMO. Mol Cell (2013) 2.12
Dietary (poly)phenolics in human health: structures, bioavailability, and evidence of protective effects against chronic diseases. Antioxid Redox Signal (2012) 1.96
Polyphenols and human health: prevention of disease and mechanisms of action. Nutrients (2010) 1.66
The neuroprotective potential of flavonoids: a multiplicity of effects. Genes Nutr (2008) 1.61
Blueberry-induced changes in spatial working memory correlate with changes in hippocampal CREB phosphorylation and brain-derived neurotrophic factor (BDNF) levels. Free Radic Biol Med (2008) 1.50
The effect of dietary nitrate on salivary, plasma, and urinary nitrate metabolism in humans. Free Radic Biol Med (2003) 1.48
Neuroinflammation: modulation by flavonoids and mechanisms of action. Mol Aspects Med (2011) 1.24
Activation of pro-survival Akt and ERK1/2 signalling pathways underlie the anti-apoptotic effects of flavanones in cortical neurons. J Neurochem (2007) 1.24
c-Jun N-terminal kinase (JNK)-mediated modulation of brain mitochondria function: new target proteins for JNK signalling in mitochondrion-dependent apoptosis. Biochem J (2003) 1.22
Growth inhibition, cell-cycle arrest and apoptosis in human T-cell leukemia by the isothiocyanate sulforaphane. Carcinogenesis (2002) 1.22
Flavonoids, cognition, and dementia: actions, mechanisms, and potential therapeutic utility for Alzheimer disease. Free Radic Biol Med (2011) 1.17
Inducible hydrogen sulfide synthesis in chondrocytes and mesenchymal progenitor cells: is H2S a novel cytoprotective mediator in the inflamed joint? J Cell Mol Med (2012) 1.14
(-)Epicatechin stimulates ERK-dependent cyclic AMP response element activity and up-regulates GluR2 in cortical neurons. J Neurochem (2007) 1.13
Sulforaphane as a promising molecule for fighting cancer. Mutat Res (2006) 1.12
Flavanol monomer-induced changes to the human faecal microflora. Br J Nutr (2007) 1.11
Prebiotic evaluation of cocoa-derived flavanols in healthy humans by using a randomized, controlled, double-blind, crossover intervention study. Am J Clin Nutr (2010) 1.11
Inhibition of p38/CREB phosphorylation and COX-2 expression by olive oil polyphenols underlies their anti-proliferative effects. Biochem Biophys Res Commun (2007) 1.09
Flavonoids and cognitive function: a review of human randomized controlled trial studies and recommendations for future studies. Genes Nutr (2009) 1.09
Soy-isoflavone-enriched foods and inflammatory biomarkers of cardiovascular disease risk in postmenopausal women: interactions with genotype and equol production. Am J Clin Nutr (2005) 1.08
Antitumor activity of sustained N-myc reduction in rhabdomyosarcomas and transcriptional block by antigene therapy. Clin Cancer Res (2011) 1.05
MAPK signaling in neurodegeneration: influences of flavonoids and of nitric oxide. Neurobiol Aging (2002) 1.05
Distribution of [3H]trans-resveratrol in rat tissues following oral administration. Br J Nutr (2006) 1.04
The citrus flavanone naringenin inhibits inflammatory signalling in glial cells and protects against neuroinflammatory injury. Arch Biochem Biophys (2009) 1.03
Dietary flavonoids as potential neuroprotectants. Biol Chem (2002) 1.03
Modulation of phase II enzymes by sulforaphane: implications for its cardioprotective potential. J Agric Food Chem (2009) 1.03
Sulforaphane as a potential protective phytochemical against neurodegenerative diseases. Oxid Med Cell Longev (2013) 1.03
Substrate specificity of human glutamine transaminase K as an aminotransferase and as a cysteine S-conjugate beta-lyase. Arch Biochem Biophys (2008) 1.00
Association between imatinib transporters and metabolizing enzymes genotype and response in newly diagnosed chronic myeloid leukemia patients receiving imatinib therapy. Haematologica (2012) 1.00
Metabolism of anthocyanins by human gut microflora and their influence on gut bacterial growth. J Agric Food Chem (2012) 0.99
The impact of flavonoids on spatial memory in rodents: from behaviour to underlying hippocampal mechanisms. Genes Nutr (2009) 0.99
Micronuclei frequencies in hospital workers occupationally exposed to low levels of ionizing radiation: influence of smoking status and other factors. Mutagenesis (2002) 0.98
Stress-induced senescence in human and rodent astrocytes. Exp Cell Res (2010) 0.97
Inflammation-induced alteration of astrocyte mitochondrial dynamics requires autophagy for mitochondrial network maintenance. Cell Metab (2013) 0.97
Doxorubicin induces early lipid peroxidation associated with changes in glucose transport in cultured cardiomyocytes. Biochim Biophys Acta (2002) 0.96
Activation of glutathione peroxidase via Nrf1 mediates genistein's protection against oxidative endothelial cell injury. Biochem Biophys Res Commun (2006) 0.96
Sulforaphane treatment protects skeletal muscle against damage induced by exhaustive exercise in rats. J Appl Physiol (1985) (2009) 0.96
Cardiotoxic effects, or lack thereof, of anti-ErbB2 immunoagents. FASEB J (2009) 0.95
Natural isothiocyanates: genotoxic potential versus chemoprevention. Mutat Res (2011) 0.95
Micronuclei in humans induced by exposure to low level of ionizing radiation: influence of polymorphisms in DNA repair genes. Mutat Res (2005) 0.94
Cyanidin-3-O-glucoside protection against TNF-α-induced endothelial dysfunction: involvement of nuclear factor-κB signaling. J Agric Food Chem (2010) 0.94
Flavonoids as modulators of memory and learning: molecular interactions resulting in behavioural effects. Proc Nutr Soc (2012) 0.94
Recommending flavanols and procyanidins for cardiovascular health: current knowledge and future needs. Mol Aspects Med (2010) 0.93
Flavonoid-rich fruit and vegetables improve microvascular reactivity and inflammatory status in men at risk of cardiovascular disease--FLAVURS: a randomized controlled trial. Am J Clin Nutr (2014) 0.93
Differential antiproliferative activity of new benzimidazole-4,7-diones. Farmaco (2004) 0.93
Sulforaphane increases the efficacy of doxorubicin in mouse fibroblasts characterized by p53 mutations. Mutat Res (2006) 0.93
Micronucleus frequency in human peripheral blood lymphocytes as a biomarker for the early detection of colorectal cancer risk. Mutagenesis (2014) 0.93
Dietary levels of pure flavonoids improve spatial memory performance and increase hippocampal brain-derived neurotrophic factor. PLoS One (2013) 0.92
Do mitochondriotropic antioxidants prevent chlorinative stress-induced mitochondrial and cellular injury? Antioxid Redox Signal (2008) 0.92
Hydroxytyrosol inhibits the proliferation of human colon adenocarcinoma cells through inhibition of ERK1/2 and cyclin D1. Mol Nutr Food Res (2009) 0.91
Moderate Champagne consumption promotes an acute improvement in acute endothelial-independent vascular function in healthy human volunteers. Br J Nutr (2009) 0.91
Protective effects of cyanidin-3-O-beta-glucopyranoside against UVA-induced oxidative stress in human keratinocytes. Photochem Photobiol (2005) 0.91
H2O2 preconditioning modulates phase II enzymes through p38 MAPK and PI3K/Akt activation. Am J Physiol Heart Circ Physiol (2011) 0.91
Polymorphisms in OCTN1 and OCTN2 transporters genes are associated with prolonged time to progression in unresectable gastrointestinal stromal tumours treated with imatinib therapy. Pharmacol Res (2012) 0.91
Plasma antioxidant enzymes and clastogenic factors as possible biomarkers of colorectal cancer risk. Mutat Res (2011) 0.91
Sulforaphane as a promising molecule for fighting cancer. Cancer Treat Res (2014) 0.91
53BP1 contributes to a robust genomic stability in human fibroblasts. Aging (Albany NY) (2011) 0.90
Green tea protection of hypoxia/reoxygenation injury in cultured cardiac cells. J Nutr Biochem (2002) 0.90
Criteria for validation and selection of cognitive tests for investigating the effects of foods and nutrients. Nutr Rev (2014) 0.90
Quercetin reduces inflammatory responses in LPS-stimulated cardiomyoblasts. Oxid Med Cell Longev (2012) 0.90
Daily consumption of an aqueous green tea extract supplement does not impair liver function or alter cardiovascular disease risk biomarkers in healthy men. J Nutr (2008) 0.90
Soy-isoflavone-enriched foods and markers of lipid and glucose metabolism in postmenopausal women: interactions with genotype and equol production. Am J Clin Nutr (2006) 0.89
Flavonoid characterization and antioxidant activity of hydroalcoholic extracts from Achillea ligustica All. J Pharm Biomed Anal (2009) 0.89
Procyanidin, anthocyanin, and chlorogenic acid contents of highbush and lowbush blueberries. J Agric Food Chem (2012) 0.89
Caffeic acid, tyrosol and p-coumaric acid are potent inhibitors of 5-S-cysteinyl-dopamine induced neurotoxicity. Arch Biochem Biophys (2010) 0.89
Spectrum of chromosomal aberrations in peripheral lymphocytes of hospital workers occupationally exposed to low doses of ionizing radiation. Mutat Res (2004) 0.88
Rational approach to discover multipotent anti-Alzheimer drugs. J Med Chem (2005) 0.88
Polyphenols in exercise performance and prevention of exercise-induced muscle damage. Oxid Med Cell Longev (2013) 0.87
Phospholipase D stimulation is required for sphingosine-1-phosphate activation of actin stress fibre assembly in human airway epithelial cells. Cell Signal (2002) 0.87
Blueberry supplementation induces spatial memory improvements and region-specific regulation of hippocampal BDNF mRNA expression in young rats. Psychopharmacology (Berl) (2012) 0.87
The pro-inflammatory oxidant hypochlorous acid induces Bax-dependent mitochondrial permeabilisation and cell death through AIF-/EndoG-dependent pathways. Cell Signal (2006) 0.87
Prebiotic feeding elevates central brain derived neurotrophic factor, N-methyl-D-aspartate receptor subunits and D-serine. Neurochem Int (2013) 0.87
Exposure to low environmental levels of benzene: evaluation of micronucleus frequencies and S-phenylmercapturic acid excretion in relation to polymorphisms in genes encoding metabolic enzymes. Mutat Res (2010) 0.87
Clinical relevance of pharmacogenetics in gastrointestinal stromal tumor treatment in the era of personalized therapy. Pharmacogenomics (2013) 0.86
Proteomic biomarkers of peripheral blood mononuclear cells obtained from postmenopausal women undergoing an intervention with soy isoflavones. Am J Clin Nutr (2007) 0.86
Neuroprotective effects of cyanidin 3-O-glucopyranoside on amyloid beta (25-35) oligomer-induced toxicity. Neurosci Lett (2010) 0.86
Effect of plasma membrane cholesterol depletion on glucose transport regulation in leukemia cells. PLoS One (2012) 0.86
The reaction of flavanols with nitrous acid protects against N-nitrosamine formation and leads to the formation of nitroso derivatives which inhibit cancer cell growth. Free Radic Biol Med (2005) 0.86
Dietary phenolic acids act as effective antioxidants in membrane models and in cultured cells, exhibiting proapoptotic effects in leukaemia cells. Oxid Med Cell Longev (2012) 0.86
Evaluation of the antioxidant and cytotoxic activity of arzanol, a prenylated alpha-pyrone-phloroglucinol etherodimer from Helichrysum italicum subsp.microphyllum. Chem Biol Interact (2006) 0.86
Modulation of peroxynitrite-induced fibroblast injury by hesperetin: a role for intracellular scavenging and modulation of ERK signalling. Biochem Biophys Res Commun (2006) 0.86
Neuroprotective effect of sulforaphane in 6-hydroxydopamine-lesioned mouse model of Parkinson's disease. Neurotoxicology (2013) 0.86