Published in Curr Top Med Chem on January 01, 2010
Pulicatins A-E, neuroactive thiazoline metabolites from cone snail-associated bacteria. J Nat Prod (2010) 1.05
Agomelatine: mechanism of action and pharmacological profile in relation to antidepressant properties. Br J Pharmacol (2014) 0.80
Predictive in silico studies of human 5-hydroxytryptamine receptor subtype 2B (5-HT2B) and valvular heart disease. Curr Top Med Chem (2013) 0.76
C4 phenyl aporphines with selective h5-HT(2B) receptor affinity. Bioorg Med Chem Lett (2015) 0.75
Sympatry inference and network analysis in biogeography. Syst Biol (2008) 1.38
Exploring the counterion atmosphere around DNA: what can be learned from molecular dynamics simulations? Biophys J (2004) 1.11
Theoretical study of the guanine --> 6-thioguanine substitution in duplexes, triplexes, and tetraplexes. J Am Chem Soc (2004) 0.89
Cardiac autonomic adaptations in elite Spanish soccer players during preseason. Int J Sports Physiol Perform (2012) 0.89
Theoretical study of alkyl-pi and aryl-pi interactions. Reconciling theory and experiment. J Org Chem (2002) 0.87
Discovery and characterization of 4'-(2-furyl)-N-pyridin-3-yl-4,5'-bipyrimidin-2'-amine (LAS38096), a potent, selective, and efficacious A2B adenosine receptor antagonist. J Med Chem (2007) 0.86
Synthesis and binding affinity of new pyrazole and isoxazole derivatives as potential atypical antipsychotics. Bioorg Med Chem Lett (2007) 0.86
Antiparallel triple helices. Structural characteristics and stabilization by 8-amino derivatives. J Am Chem Soc (2003) 0.86
Multistructure 3D-QSAR studies on a series of conformationally constrained butyrophenones docked into a new homology model of the 5-HT2A receptor. J Med Chem (2007) 0.85
Anthropometric and physiological characteristics of young soccer players according to their playing positions: relevance for competition success. J Strength Cond Res (2011) 0.85
The influence of a congested calendar on physical performance in elite soccer. J Strength Cond Res (2011) 0.85
Extensive linkage disequilibrium mapping at HTR2A and DRD3 for schizophrenia susceptibility genes in the Galician population. Schizophr Res (2006) 0.83
Destabilization of quadruplex DNA by 8-aminoguanine. Chembiochem (2006) 0.82
In silico directed chemical probing of the adenosine receptor family. Bioorg Med Chem (2010) 0.82
Effect of phosphodiesterase 7 (PDE7) inhibitors in experimental autoimmune encephalomyelitis mice. Discovery of a new chemically diverse family of compounds. J Med Chem (2012) 0.82
A common haplotype of DRD3 affected by recent positive selection is associated with protection from schizophrenia. Hum Genet (2008) 0.81
Pyrimidine derivatives as potent and selective A3 adenosine receptor antagonists. J Med Chem (2010) 0.81
Effect of bulky lesions on DNA: solution structure of a DNA duplex containing a cholesterol adduct. J Biol Chem (2004) 0.81
Parallel regulation by olanzapine of the patterns of expression of 5-HT2A and D3 receptors in rat central nervous system and blood cells. Neuropharmacology (2006) 0.80
Natural tetraponerines: a general synthesis and antiproliferative activity. J Org Chem (2014) 0.80
Synthesis, 3D-QSAR, and structural modeling of benzolactam derivatives with binding affinity for the D(2) and D(3) receptors. ChemMedChem (2010) 0.79
Identification in silico and experimental validation of novel phosphodiesterase 7 inhibitors with efficacy in experimental autoimmune encephalomyelitis mice. ACS Chem Neurosci (2012) 0.79
Psychosocial and behavioural determinants of the implementation of Pharmaceutical Care in Spain. Pharm World Sci (2008) 0.78
Structural properties of g,t-parallel duplexes. J Nucleic Acids (2010) 0.77
Modulation of cAMP-specific PDE without emetogenic activity: new sulfide-like PDE7 inhibitors. J Med Chem (2014) 0.77
A novel multilevel statistical method for the study of the relationships between multireceptorial binding affinity profiles and in vivo endpoints. Mol Pharmacol (2009) 0.76
A new chemical tool (C0036E08) supports the role of adenosine A(2B) receptors in mediating human mast cell activation. Biochem Pharmacol (2008) 0.76
Functional characterization of serotonin receptors in rat isolated aorta. Biol Pharm Bull (2002) 0.76
Synthesis, binding affinity, and molecular docking analysis of new benzofuranone derivatives as potential antipsychotics. J Med Chem (2008) 0.76
Towards a dynamic analysis of weighted networks in biogeography. Syst Biol (2011) 0.76
Different pharmacological properties of two equipotent antagonists (clozapine and rauwolscine) for 5-HT2B receptors in rat stomach fundus. Biochem Pharmacol (2003) 0.76
Discovery of 5-HT6 receptor ligands based on virtual HTS. Bioorg Med Chem Lett (2007) 0.76
Synthesis and binding affinity of potential atypical antipsychotics with the tetrahydroquinazolinone motif. Bioorg Med Chem Lett (2009) 0.75
A medicinal-chemistry-guided approach to selective and druglike sigma 1 ligands. ChemMedChem (2006) 0.75
Synthesis and pharmacological evaluation of novel 1- and 8-substituted-3-furfuryl xanthines as adenosine receptor antagonists. Bioorg Med Chem (2009) 0.75
Syntheses and cytotoxicity of (R)- and (S)-7-methoxycryptopleurine. J Org Chem (2015) 0.75
Synthesis and pharmacological evaluation of novel substituted 9-deazaxanthines as A2B receptor antagonists. Eur J Med Chem (2010) 0.75
Selective and potent adenosine A3 receptor antagonists by methoxyaryl substitution on the N-(2,6-diarylpyrimidin-4-yl)acetamide scaffold. Eur J Med Chem (2012) 0.75
Membrane-disrupting iridium(iii) oligocationic organometallopeptides. Chem Commun (Camb) (2016) 0.75
Synthesis and pharmacological evaluation of novel 1,3,8- and 1,3,7,8-substituted xanthines as adenosine receptor antagonists. Bioorg Med Chem (2010) 0.75
Concise asymmetric syntheses of novel phenanthroquinolizidines. Org Biomol Chem (2016) 0.75
A preliminary study of the metabolic stability of a series of benzoxazinone derivatives as potent neuropeptide Y5 antagonists. Bioorg Med Chem Lett (2005) 0.75
Unraveling phosphodiesterase surfaces. Identification of phosphodiesterase 7 allosteric modulation cavities. Eur J Med Chem (2013) 0.75