Makoto Sawada

Author PubWeight™ 59.59‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Distribution of major histocompatibility complex class II-positive microglia and cytokine profile of Parkinson's disease brains. Acta Neuropathol 2003 1.57
2 Neuroprotective effect of exogenous microglia in global brain ischemia. J Cereb Blood Flow Metab 2006 1.35
3 Imaging of peripheral benzodiazepine receptor expression as biomarkers of detrimental versus beneficial glial responses in mouse models of Alzheimer's and other CNS pathologies. J Neurosci 2008 1.29
4 Time-dependent changes in proinflammatory and neurotrophic responses of microglia and astrocytes in a rat model of osmotic demyelination syndrome. Glia 2010 1.20
5 Minocycline prevents osmotic demyelination syndrome by inhibiting the activation of microglia. J Am Soc Nephrol 2010 1.20
6 Cellular and molecular mechanisms of Parkinson's disease: neurotoxins, causative genes, and inflammatory cytokines. Cell Mol Neurobiol 2006 1.17
7 Matrix metalloproteinase-9 contributes to kindled seizure development in pentylenetetrazole-treated mice by converting pro-BDNF to mature BDNF in the hippocampus. J Neurosci 2011 1.17
8 A link between stress and depression: shifts in the balance between the kynurenine and serotonin pathways of tryptophan metabolism and the etiology and pathophysiology of depression. Stress 2008 1.16
9 IL-4-induced selective clearance of oligomeric beta-amyloid peptide(1-42) by rat primary type 2 microglia. J Immunol 2008 1.16
10 Antidepressants inhibit interferon-gamma-induced microglial production of IL-6 and nitric oxide. Exp Neurol 2007 1.11
11 Quantum dots labeling using octa-arginine peptides for imaging of adipose tissue-derived stem cells. Biomaterials 2010 1.08
12 Existence of functional beta1- and beta2-adrenergic receptors on microglia. J Neurosci Res 2002 1.06
13 Blockade of microglial glutamate release protects against ischemic brain injury. Exp Neurol 2008 1.06
14 Temperature dependence of proton permeation through a voltage-gated proton channel. J Gen Physiol 2009 1.05
15 Stimulus-dependent regulation of the phagocyte NADPH oxidase by a VAV1, Rac1, and PAK1 signaling axis. J Biol Chem 2007 1.02
16 The HIV-1 Nef protein and phagocyte NADPH oxidase activation. J Biol Chem 2002 1.02
17 Rabies virus-induced activation of mitogen-activated protein kinase and NF-kappaB signaling pathways regulates expression of CXC and CC chemokine ligands in microglia. J Virol 2005 1.01
18 High-frequency, magnetic-field-responsive drug release from magnetic nanoparticle/organic hybrid based on hyperthermic effect. ACS Appl Mater Interfaces 2010 0.99
19 Superoxide production at phagosomal cup/phagosome through beta I protein kinase C during Fc gamma R-mediated phagocytosis in microglia. J Immunol 2004 0.97
20 Cytokine production of activated microglia and decrease in neurotrophic factors of neurons in the hippocampus of Lewy body disease brains. Acta Neuropathol 2004 0.96
21 Amyloid-beta peptides induce several chemokine mRNA expressions in the primary microglia and Ra2 cell line via the PI3K/Akt and/or ERK pathway. Neurosci Res 2006 0.93
22 Induction of matrix metalloproteinases (MMP3, MMP12 and MMP13) expression in the microglia by amyloid-beta stimulation via the PI3K/Akt pathway. Exp Gerontol 2007 0.92
23 Preservation of hematopoietic properties in transplanted bone marrow cells in the brain. J Neurosci Res 2003 0.91
24 Tonic-clonic seizures induce division of neuronal progenitor cells with concomitant changes in expression of neurotrophic factors in the brain of pilocarpine-treated mice. Brain Res Mol Brain Res 2005 0.91
25 A lentiviral expression system demonstrates that L* protein of Theiler's murine encephalomyelitis virus (TMEV) is essential for virus growth in a murine macrophage-like cell line. Virus Res 2005 0.90
26 Amyloid-beta peptides induce cell proliferation and macrophage colony-stimulating factor expression via the PI3-kinase/Akt pathway in cultured Ra2 microglial cells. FEBS Lett 2005 0.88
27 Ferritin reporter used for gene expression imaging by magnetic resonance. Biochem Biophys Res Commun 2009 0.88
28 The effects of general anesthetics on P2X7 and P2Y receptors in a rat microglial cell line. Anesth Analg 2007 0.87
29 Early and late activation of the voltage-gated proton channel during lactic acidosis through pH-dependent and -independent mechanisms. Pflugers Arch 2007 0.85
30 N-benzyl-2-(6,8-dichloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)-N-(6-(7-nitrobenzo[c][1,2,5]oxadiazol-4-ylamino)hexyl)acetamide as a new fluorescent probe for peripheral benzodiazepine receptor and microglial cell visualization. Bioconjug Chem 2007 0.84
31 Activated microglia affect the nigro-striatal dopamine neurons differently in neonatal and aged mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. J Neurosci Res 2007 0.84
32 Phosphatidylserine and phosphatidylcholine-containing liposomes inhibit amyloid beta and interferon-gamma-induced microglial activation. Free Radic Biol Med 2006 0.83
33 A lentiviral expression system demonstrates that L* protein of Theiler's murine encephalomyelitis virus (TMEV) has an anti-apoptotic effect in a macrophage cell line. Microb Pathog 2005 0.83
34 Interleukin-6 induces prostaglandin E(2) synthesis in mouse astrocytes. J Mol Neurosci 2009 0.83
35 Increases in intracellular pH facilitate endocytosis and decrease availability of voltage-gated proton channels in osteoclasts and microglia. J Physiol 2013 0.83
36 Radiosynthesis and in vivo evaluation of two imidazopyridineacetamides, [(11)C]CB184 and [ (11)C]CB190, as a PET tracer for 18 kDa translocator protein: direct comparison with [ (11)C](R)-PK11195. Ann Nucl Med 2015 0.83
37 Peripheral injection of lipopolysaccharide enhances expression of inflammatory cytokines in murine locus coeruleus: possible role of increased norepinephrine turnover. J Neurochem 2005 0.82
38 New fluorescent probes targeting the mitochondrial-located translocator protein 18 kDa (TSPO) as activated microglia imaging agents. Pharm Res 2011 0.82
39 Vitamin K2 ameliorates experimental autoimmune encephalomyelitis in Lewis rats. J Neuroimmunol 2005 0.82
40 Transforming growth factor-beta1 upregulates keratan sulfate and chondroitin sulfate biosynthesis in microglias after brain injury. Brain Res 2009 0.82
41 Hemokinin-1 gene expression is upregulated in microglia activated by lipopolysaccharide through NF-κB and p38 MAPK signaling pathways. PLoS One 2012 0.82
42 Effects of a brain-engraftable microglial cell line expressing anti-prion scFv antibodies on survival times of mice infected with scrapie prions. Cell Mol Neurobiol 2011 0.82
43 Cell cycle-dependent regulation of kainate-induced inward currents in microglia. Biochem Biophys Res Commun 2006 0.81
44 Electrosprayed synthesis of red-blood-cell-like particles with dual modality for magnetic resonance and fluorescence imaging. Small 2010 0.81
45 Marked induction of inducible nitric oxide synthase and tumor necrosis factor-alpha in rat CD40+ microglia by comparison to CD40- microglia. J Neuroimmunol 2009 0.81
46 4-Hydroxy-2-nonenal upregulates and phosphorylates cytosolic phospholipase A(2) in cultured Ra2 microglial cells via MAPK pathways. Neuropathology 2011 0.81
47 Distinct cell death mechanisms by Theiler's murine encephalomyelitis virus (TMEV) infection in microglia and macrophage. Neurosci Lett 2002 0.81
48 Two activated stages of microglia and PET imaging of peripheral benzodiazepine receptors with [(11)C]PK11195 in rats. Ann Nucl Med 2010 0.81
49 Delayed neural damage is induced by iNOS-expressing microglia in a brain injury model. Neurosci Lett 2010 0.80
50 Localization of cyclooxygenase-2 induced following traumatic spinal cord injury. Neurosci Res 2005 0.80
51 Microglial cell cycle-associated proteins control microglial proliferation in vivo and in vitro and are regulated by GM-CSF and density-dependent inhibition. J Neurosci Res 2003 0.80
52 Glial cell line-derived neurotrophic factor enhances survival of GM-CSF dependent rat GMIR1-microglial cells. Neurosci Res 2002 0.80
53 In vivo imaging of microglial activation using a peripheral benzodiazepine receptor ligand: [11C]PK-11195 and animal PET following ethanol injury in rat striatum. Ann Nucl Med 2008 0.80
54 Double-stranded RNA stimulates chemokine expression in microglia through vacuolar pH-dependent activation of intracellular signaling pathways. J Neurochem 2005 0.79
55 Inhibition of voltage-gated proton channels by local anaesthetics in GMI-R1 rat microglia. J Physiol 2011 0.78
56 Identification of ligands binding specifically to inflammatory intestinal mucosa using phage display. Clin Exp Pharmacol Physiol 2007 0.78
57 Neuroprotective and neurotoxic phenotypes of activated microglia in neonatal mice with respective MPTP- and ethanol-induced brain injury. Neurodegener Dis 2010 0.78
58 In vivo imaging of transplanted islets labeled with a novel cationic nanoparticle. PLoS One 2013 0.78
59 Molecular pathologies of and enzyme replacement therapies for lysosomal diseases. CNS Neurol Disord Drug Targets 2006 0.77
60 Protective effect of INI-0602, a gap junction inhibitor, on dopaminergic neurodegeneration of mice with unilateral 6-hydroxydopamine injection. J Neural Transm (Vienna) 2014 0.77
61 Singlet-oxygen-sensitizing near-infrared-fluorescent multimodal nanoparticles. Angew Chem Int Ed Engl 2013 0.77
62 Photouncaging nanoparticles for MRI and fluorescence imaging in vitro and in vivo. ACS Nano 2013 0.77
63 Phospholipids modulate superoxide and nitric oxide production by lipopolysaccharide and phorbol 12-myristate-13-acetate-activated microglia. Neurochem Int 2006 0.77
64 Pepstatin A induces extracellular acidification distinct from aspartic protease inhibition in microglial cell lines. Glia 2003 0.76
65 Glutamate release from astrocyte cell-line GL261 via alterations in the intracellular ion environment. J Neural Transm (Vienna) 2013 0.76
66 The effect of lipid emulsion on intracellular bupivacaine as a mechanism of lipid resuscitation: an electrophysiological study using voltage-gated proton channels. Anesth Analg 2013 0.76
67 [Alzheimer's disease and microglia]. Rinsho Shinkeigaku 2011 0.75
68 Nanoparticles speckled by ready-to-conjugate lanthanide complexes for multimodal imaging. Nanoscale 2015 0.75
69 Magnetically induced orientation of mesochannels in mesoporous silica films at 30 tesla. Chem Asian J 2007 0.75