PubRank

A Israël

Author PubWeight™ 122.65‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The DNA binding subunit of NF-kappa B is identical to factor KBF1 and homologous to the rel oncogene product. Cell 1990 9.37
2 Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation. Cell 1998 6.48
3 A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE. Mol Cell 2000 5.53
4 Detailed analysis of the mouse H-2Kb promoter: enhancer-like sequences and their role in the regulation of class I gene expression. Cell 1986 5.39
5 The Notch1 receptor is cleaved constitutively by a furin-like convertase. Proc Natl Acad Sci U S A 1998 3.99
6 X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-kappaB signaling. Nat Genet 2001 3.86
7 The precursor of NF-kappa B p50 has I kappa B-like functions. Cell 1992 3.82
8 NF-kappa B and related proteins: Rel/dorsal homologies meet ankyrin-like repeats. Trends Biochem Sci 1992 3.81
9 A common positive trans-acting factor binds to enhancer sequences in the promoters of mouse H-2 and beta 2-microglobulin genes. Proc Natl Acad Sci U S A 1987 3.80
10 Genomic rearrangement in NEMO impairs NF-kappaB activation and is a cause of incontinentia pigmenti. The International Incontinentia Pigmenti (IP) Consortium. Nature 2000 3.61
11 NEMO/IKK gamma-deficient mice model incontinentia pigmenti. Mol Cell 2000 3.60
12 The characterization of the promoter of the gene encoding the p50 subunit of NF-kappa B indicates that it participates in its own regulation. EMBO J 1992 2.86
13 Promoter analysis of the gene encoding the I kappa B-alpha/MAD3 inhibitor of NF-kappa B: positive regulation by members of the rel/NF-kappa B family. EMBO J 1993 2.71
14 Purification of KBF1, a common factor binding to both H-2 and beta 2-microglobulin enhancers. EMBO J 1987 2.71
15 Functional interaction between SEL-10, an F-box protein, and the nuclear form of activated Notch1 receptor. J Biol Chem 2001 2.71
16 Cytoplasmic retention, DNA binding and processing of the NF-kappa B p50 precursor are controlled by a small region in its C-terminus. EMBO J 1991 2.39
17 I kappa B epsilon, a novel member of the I kappa B family, controls RelA and cRel NF-kappa B activity. EMBO J 1997 2.26
18 Processing of the precursor of NF-kappa B by the HIV-1 protease during acute infection. Nature 1991 2.18
19 Inhibition of transcription factors belonging to the rel/NF-kappa B family by a transdominant negative mutant. EMBO J 1991 2.15
20 N- and C-terminal sequences control degradation of MAD3/I kappa B alpha in response to inducers of NF-kappa B activity. Mol Cell Biol 1995 2.12
21 Inhibition of the DNA-binding activity of Drosophila suppressor of hairless and of its human homolog, KBF2/RBP-J kappa, by direct protein-protein interaction with Drosophila hairless. Genes Dev 1994 2.08
22 Invasive Shigella flexneri activates NF-kappa B through a lipopolysaccharide-dependent innate intracellular response and leads to IL-8 expression in epithelial cells. J Immunol 2000 2.05
23 I kappa B proteins: structure, function and regulation. Semin Cancer Biol 1997 2.01
24 IkappaB alpha is a target for the mitogen-activated 90 kDa ribosomal S6 kinase. EMBO J 1997 1.91
25 Tumor necrosis factor stimulates transcription of HIV-1 in human T lymphocytes, independently and synergistically with mitogens. J Immunol 1989 1.87
26 The regulation and expression of MHC class I genes. Immunol Today 1990 1.76
27 Ubiquitin-mediated processing of NF-kappa B transcriptional activator precursor p105. Reconstitution of a cell-free system and identification of the ubiquitin-carrier protein, E2, and a novel ubiquitin-protein ligase, E3, involved in conjugation. J Biol Chem 1995 1.67
28 SCF(beta)(-TrCP) ubiquitin ligase-mediated processing of NF-kappaB p105 requires phosphorylation of its C-terminus by IkappaB kinase. EMBO J 2000 1.55
29 Atypical forms of incontinentia pigmenti in male individuals result from mutations of a cytosine tract in exon 10 of NEMO (IKK-gamma). Am J Hum Genet 2001 1.54
30 Siah-1 binds and regulates the function of Numb. Proc Natl Acad Sci U S A 2001 1.33
31 Phorbol esters and cytokines regulate the expression of the NEMO-related protein, a molecule involved in a NF-kappa B-independent pathway. J Biol Chem 2000 1.32
32 Tax induces nuclear translocation of NF-kappa B through dissociation of cytoplasmic complexes containing p105 or p100 but does not induce degradation of I kappa B alpha/MAD3. J Virol 1994 1.27
33 Deciphering the pathway from the TCR to NF-kappaB. Cell Death Differ 2006 1.26
34 IkappaBepsilon-deficient mice: reduction of one T cell precursor subspecies and enhanced Ig isotype switching and cytokine synthesis. J Immunol 1999 1.24
35 Structural motifs involved in ubiquitin-mediated processing of the NF-kappaB precursor p105: roles of the glycine-rich region and a downstream ubiquitination domain. Mol Cell Biol 1999 1.22
36 Preliminary characterization of the particles from productive and abortive infections of L cells by fowl plague virus. Ann Microbiol (Paris) 1979 1.22
37 Regulation of IkappaBbeta degradation. Similarities to and differences from IkappaBalpha. J Biol Chem 1997 1.13
38 Phosphorylation of p105 PEST sequence via a redox-insensitive pathway up-regulates processing of p50 NF-kappaB. J Biol Chem 1996 1.11
39 Cytosol is the prime compartment of hepatitis B virus X protein where it colocalizes with the proteasome. Oncogene 1998 1.10
40 Mechanisms of ubiquitin-mediated, limited processing of the NF-kappaB1 precursor protein p105. Biochimie 2001 1.10
41 Direct association and nuclear import of the hepatitis B virus X protein with the NF-kappaB inhibitor IkappaBalpha. Mol Cell Biol 1999 1.09
42 NEMO/IKK gamma: linking NF-kappa B to human disease. Trends Mol Med 2001 1.04
43 Two factors, IRF1 and KBF1/NF-kappa B, cooperate during induction of MHC class I gene expression by interferon alpha beta or Newcastle disease virus. C R Acad Sci III 1993 1.00
44 Productive and abortive infection of L cells by fowl plague virus (FPV): comparison of in vivo and in vitro translation products of the virus mRNAs. J Gen Virol 1980 0.99
45 Control of NF-kappa B activity by the I kappa B beta inhibitor. Immunobiology 1997 0.95
46 Signal transduction. IkappaB kinase all zipped up. Nature 1997 0.95
47 Altered expression of tyrosine kinases of the Src and Syk families in human T-cell leukemia virus type 1-infected T-cell lines. J Virol 1999 0.93
48 Activation of NF-kappaB in the mouse spinal cord following sciatic nerve transection. Exp Brain Res 2005 0.93
49 A temperature-dependent host range mutant of fowl plague virus (FPV). Virology 1980 0.92
50 Activation of NF-kappa B by the Tax protein of HTLV-1. Immunobiology 1995 0.89
51 Alzheimer's disease. In search of gamma-secretase. Nature 1999 0.87
52 NF-kappa B defects in humans: the NEMO/incontinentia pigmenti connection. Sci STKE 2000 0.86
53 In vivo identification of lymphocyte subsets exhibiting transcriptionally active NF-kappaB/Rel complexes. Int Immunol 2000 0.84
54 Genotypic and phenotypic characterization of a mammalian cell-adapted mutant of fowl plague virus (FPV). J Gen Virol 1980 0.83
55 Kappa B binding proteins are constitutively expressed in an IL-2 autocrine human T cell line. J Immunol 1991 0.83
56 Injury-induced NF-kappaB activation in the hippocampus: implications for neuronal survival. FASEB J 2004 0.83
57 Characterization of a new tissue-specific transcription factor binding to the simian virus 40 enhancer TC-II (NF-kappa B) element. Mol Cell Biol 1992 0.82
58 NF-kappa B is developmentally regulated during spermatogenesis in mice. Dev Dyn 2000 0.81
59 Reconstitution of the NF-kappa B system in Saccharomyces cerevisiae for isolation of effectors by phenotype modulation. Yeast 1997 0.81
60 Latex fetuin spheres as probes for influenza virus neuraminidase in productively and abortively infected cells. Arch Virol 1979 0.78
61 Negative regulation of the gene for H-2Kb class I antigen by adenovirus 12-E1A is mediated by a CAA repeated element. J Biol Chem 1993 0.78
62 Rapid assessment of albumin concentration by immunoturbidimetry. Clin Chem 1985 0.75
63 [Contraception by subcutaneous Norplant implants. 300 cases]. Contracept Fertil Sex 1998 0.75
64 [The rel/NF-kappa B family of transcription factors: a novel mechanism to control gene expression]. Pathol Biol (Paris) 1992 0.75
65 Presenilins. Curr Biol 2001 0.75
66 Cooperatively between an upstream TATA-like sequence and a CAA repeated element mediates E1A-dependent negative repression of the H-2Kb class I gene. J Biol Chem 1995 0.75