PubRank

Stefania Di Marco

Author PubWeight™ 19.82‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Crystal structure of a eukaryotic zinc-dependent histone deacetylase, human HDAC8, complexed with a hydroxamic acid inhibitor. Proc Natl Acad Sci U S A 2004 3.27
2 HDACs, histone deacetylation and gene transcription: from molecular biology to cancer therapeutics. Cell Res 2007 2.60
3 Substrate binding to histone deacetylases as shown by the crystal structure of the HDAC8-substrate complex. EMBO Rep 2007 2.01
4 A proprotein convertase subtilisin-like/kexin type 9 (PCSK9) C-terminal domain antibody antigen-binding fragment inhibits PCSK9 internalization and restores low density lipoprotein uptake. J Biol Chem 2010 1.32
5 A PCSK9-binding antibody that structurally mimics the EGF(A) domain of LDL-receptor reduces LDL cholesterol in vivo. J Lipid Res 2010 1.29
6 Potent inhibitors of subgenomic hepatitis C virus RNA replication through optimization of indole-N-acetamide allosteric inhibitors of the viral NS5B polymerase. J Med Chem 2005 1.01
7 Studies on the mode of Ku interaction with DNA. J Biol Chem 2002 0.96
8 Crystal structure of the quorum-sensing protein TraM and its interaction with the transcriptional regulator TraR. J Biol Chem 2004 0.95
9 Identification and biological evaluation of a series of 1H-benzo[de]isoquinoline-1,3(2H)-diones as hepatitis C virus NS5B polymerase inhibitors. J Med Chem 2009 0.89
10 Determination of the stoichiometry of noncovalent complexes using reverse-phase high-performance liquid chromatography coupled with electrospray ion trap mass spectrometry. Anal Biochem 2002 0.86
11 Discovery of (7R)-14-cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl) amino}-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylic acid (MK-3281), a potent and orally bioavailable finger-loop inhibitor of the hepatitis C virus NS5B polymerase. J Med Chem 2010 0.86
12 Optimization of thienopyrrole-based finger-loop inhibitors of the hepatitis C virus NS5B polymerase. ChemMedChem 2009 0.81
13 The design and enzyme-bound crystal structure of indoline based peptidomimetic inhibitors of hepatitis C virus NS3 protease. J Med Chem 2004 0.79
14 Nucleic acid binding of the RTN1-C C-terminal region: toward the functional role of a reticulon protein. Biochemistry 2009 0.79
15 Oligomerization of Sulfolobus solfataricus signature amidase is promoted by acidic pH and high temperature. Archaea 2005 0.78
16 Crystallization and preliminary X-ray diffraction studies of the transcriptional regulator TraR bound to its cofactor and to a specific DNA sequence. Acta Crystallogr D Biol Crystallogr 2002 0.77
17 Cyclic nucleotide phosphodiesterase activity in stem cells of human periodontal ligament (PDL-MSCs) before and after osteogenic induction. Oral Surg Oral Med Oral Pathol Oral Radiol 2012 0.76
18 Crystallization and preliminary X-ray diffraction studies of the quorum-sensing regulator TraM from Agrobacterium tumefaciens. Acta Crystallogr D Biol Crystallogr 2003 0.75