PubRank

Keiko Taguchi

Author PubWeight™ 42.83‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1. Nat Cell Biol 2010 6.95
2 Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming. Cancer Cell 2012 3.90
3 Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selection. J Cell Biol 2010 2.32
4 Genetic versus chemoprotective activation of Nrf2 signaling: overlapping yet distinct gene expression profiles between Keap1 knockout and triterpenoid-treated mice. Carcinogenesis 2009 1.85
5 Genetic or pharmacologic amplification of nrf2 signaling inhibits acute inflammatory liver injury in mice. Toxicol Sci 2008 1.52
6 Oxidation of proximal protein sulfhydryls by phenanthraquinone, a component of diesel exhaust particles. Chem Res Toxicol 2002 1.31
7 Ursodeoxycholic acid stimulates Nrf2-mediated hepatocellular transport, detoxification, and antioxidative stress systems in mice. Am J Physiol Gastrointest Liver Physiol 2008 1.27
8 Deletion of nuclear factor-E2-related factor-2 leads to rapid onset and progression of nutritional steatohepatitis in mice. Am J Physiol Gastrointest Liver Physiol 2009 1.21
9 Nrf2-deficiency creates a responsive microenvironment for metastasis to the lung. Carcinogenesis 2010 1.12
10 Nrf2 counteracts cholestatic liver injury via stimulation of hepatic defense systems. Biochem Biophys Res Commun 2009 1.11
11 The circadian clock regulates rhythmic activation of the NRF2/glutathione-mediated antioxidant defense pathway to modulate pulmonary fibrosis. Genes Dev 2014 1.08
12 The interactions of 9,10-phenanthrenequinone with glyceraldehyde-3-phosphate dehydrogenase (GAPDH), a potential site for toxic actions. Chem Biol Interact 2005 1.07
13 Cytoprotective role of Nrf2/Keap1 system in methylmercury toxicity. Biochem Biophys Res Commun 2007 1.03
14 Interference with BRCA2, which localizes to the centrosome during S and early M phase, leads to abnormal nuclear division. Biochem Biophys Res Commun 2007 1.01
15 Critical role of Nrf2 in oxidative stress-induced retinal ganglion cell death. J Neurochem 2013 0.99
16 Nrf2 inhibits hepatic iron accumulation and counteracts oxidative stress-induced liver injury in nutritional steatohepatitis. J Gastroenterol 2012 0.93
17 The transcriptome of Nrf2-/- mice provides evidence for impaired cell cycle progression in the development of cigarette smoke-induced emphysematous changes. Toxicol Sci 2010 0.93
18 Oxidative-stress-inducible qorA encodes an NADPH-dependent quinone oxidoreductase catalysing a one-electron reduction in Staphylococcus aureus. Microbiology 2003 0.92
19 Inducible disruption of autophagy in the lung causes airway hyper-responsiveness. Biochem Biophys Res Commun 2010 0.88
20 Metabolic stress response implicated in diabetic retinopathy: the role of calpain, and the therapeutic impact of calpain inhibitor. Neurobiol Dis 2012 0.88
21 Initial response and cellular protection through the Keap1/Nrf2 system during the exposure of primary mouse hepatocytes to 1,2-naphthoquinone. Chem Res Toxicol 2011 0.87
22 Keap1 inhibition attenuates glomerulosclerosis. Nephrol Dial Transplant 2014 0.85
23 Inhibition of endothelial nitric oxide synthase activity and suppression of endothelium-dependent vasorelaxation by 1,2-naphthoquinone, a component of diesel exhaust particles. Arch Toxicol 2005 0.84
24 Abnormal nocturnal blood pressure profile is associated with mild cognitive impairment in the elderly: the J-SHIPP study. Hypertens Res 2009 0.83
25 NF-E2-related factor 2 promotes compensatory liver hypertrophy after portal vein branch ligation in mice. Hepatology 2014 0.83
26 Postural instability is associated with brain atrophy and cognitive impairment in the elderly: the J-SHIPP study. Dement Geriatr Cogn Disord 2010 0.82
27 1,2-Naphthoquinone activates vanilloid receptor 1 through increased protein tyrosine phosphorylation, leading to contraction of guinea pig trachea. Toxicol Appl Pharmacol 2005 0.82
28 1-Cyano-2,3-epithiopropane is a novel plant-derived chemopreventive agent which induces cytoprotective genes that afford resistance against the genotoxic alpha,beta-unsaturated aldehyde acrolein. Carcinogenesis 2009 0.81
29 A novel alternative splice variant of nicastrin and its implication in Alzheimer disease. Life Sci 2005 0.78
30 Constitutive activation of nuclear factor-E2-related factor 2 induces biotransformation enzyme and transporter expression in livers of mice with hepatocyte-specific deletion of Kelch-like ECH-associated protein 1. J Biochem Mol Toxicol 2011 0.78
31 Lymphocyte-specific protein tyrosine kinase is a novel risk gene for Alzheimer disease. J Neurol Sci 2005 0.76
32 [A case of Fisher syndrome with multiple cranial neuropathy and abnormal EEG findings]. Nihon Ronen Igakkai Zasshi 2012 0.76
33 Molecular evidence of presenilin 1 mutation in familial early onset dementia. Am J Med Genet 2002 0.76
34 Decreased enzyme activity of hepatic thioredoxin reductase and glutathione reductase in rabbits by prolonged exposure to inorganic arsenate. Environ Toxicol 2003 0.75
35 [The medial temporal area and parietal lobe are involved in epileptic polyopia and palinopsia: A case report]. Rinsho Shinkeigaku 2012 0.75
36 Glutathione peroxidase mimics as novel antioxidants from vegetables. Biofactors 2005 0.75
37 Interaction of 9,10-phenanthraquinone with dithiol causes oxidative modification of Cu,Zn-superoxide dismutase (SOD) through redox cycling. J Toxicol Sci 2013 0.75
38 [A case of myasthenia gravis with an invasive thymoma infiltrating the superior vena cava and right atrium and causing lung metastasis]. Nihon Ronen Igakkai Zasshi 2010 0.75