Published in Proteomics on March 01, 2010
Tail-anchored membrane protein insertion into the endoplasmic reticulum. Nat Rev Mol Cell Biol (2011) 1.95
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Rapid identification of monospecific monoclonal antibodies using a human proteome microarray. Mol Cell Proteomics (2012) 1.65
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Coordinating the impact of structural genomics on the human α-helical transmembrane proteome. Nat Struct Mol Biol (2013) 1.05
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Avidity-based extracellular interaction screening (AVEXIS) for the scalable detection of low-affinity extracellular receptor-ligand interactions. J Vis Exp (2012) 1.03
Structural genomics plucks high-hanging membrane proteins. Curr Opin Struct Biol (2012) 0.98
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Integral membrane proteins and bilayer proteomics. Anal Chem (2013) 0.90
Functional specialization in nucleotide sugar transporters occurred through differentiation of the gene cluster EamA (DUF6) before the radiation of Viridiplantae. BMC Evol Biol (2011) 0.89
Revisiting the folding kinetics of bacteriorhodopsin. Protein Sci (2011) 0.89
Fluorine-19 NMR of integral membrane proteins illustrated with studies of GPCRs. Curr Opin Struct Biol (2013) 0.89
Efficient Exploration of Membrane-Associated Phenomena at Atomic Resolution. J Membr Biol (2015) 0.87
Improved recovery and identification of membrane proteins from rat hepatic cells using a centrifugal proteomic reactor. Mol Cell Proteomics (2011) 0.87
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Paracellular epithelial sodium transport maximizes energy efficiency in the kidney. J Clin Invest (2016) 0.87
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A unified multitask architecture for predicting local protein properties. PLoS One (2012) 0.84
Characterizing the human hematopoietic CDome. Front Genet (2014) 0.84
Computational modeling of membrane proteins. Proteins (2014) 0.83
Polar residues and their positional context dictate the transmembrane domain interactions of influenza A neuraminidases. J Biol Chem (2013) 0.83
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Maltose neopentyl glycol-3 (MNG-3) analogues for membrane protein study. Analyst (2015) 0.81
Life at the border: adaptation of proteins to anisotropic membrane environment. Protein Sci (2014) 0.81
Atomic-level description of protein-lipid interactions using an accelerated membrane model. Biochim Biophys Acta (2016) 0.81
Membrane protein orientation and refinement using a knowledge-based statistical potential. BMC Bioinformatics (2013) 0.80
Small-angle scattering determination of the shape and localization of human cytochrome P450 embedded in a phospholipid nanodisc environment. Acta Crystallogr D Biol Crystallogr (2015) 0.80
Protein traffic disorders: an effective high-throughput fluorescence microscopy pipeline for drug discovery. Sci Rep (2015) 0.80
A Combined Omics Approach to Generate the Surface Atlas of Human Naive CD4+ T Cells during Early T-Cell Receptor Activation. Mol Cell Proteomics (2015) 0.79
Highly parallel transport recordings on a membrane-on-nanopore chip at single molecule resolution. Nano Lett (2014) 0.79
Characterization of the membrane proteome and N-glycoproteome in BV-2 mouse microglia by liquid chromatography-tandem mass spectrometry. BMC Genomics (2014) 0.79
TMalphaDB and TMbetaDB: web servers to study the structural role of sequence motifs in α-helix and β-barrel domains of membrane proteins. BMC Bioinformatics (2015) 0.78
Streamlined Membrane Proteome Preparation for Shotgun Proteomics Analysis with Triton X-100 Cloud Point Extraction and Nanodiamond Solid Phase Extraction. Materials (Basel) (2016) 0.78
A Class of Rigid Linker-bearing Glucosides for Membrane Protein Structural Study. Chem Sci (2015) 0.77
Membrane organization and dynamics of "inner pair" and "outer pair" tryptophan residues in gramicidin channels. J Phys Chem B (2012) 0.77
Importance of indole N-H hydrogen bonding in the organization and dynamics of gramicidin channels. Biochim Biophys Acta (2013) 0.77
Comparison of bottom-up proteomic approaches for LC-MS analysis of complex proteomes. Anal Methods (2013) 0.77
TGFβ-Responsive HMOX1 Expression Is Associated with Stemness and Invasion in Glioblastoma Multiforme. Stem Cells (2016) 0.76
Tat peptide-mediated soluble expression of the membrane protein LSECtin-CRD in Escherichia coli. PLoS One (2013) 0.76
Genome-wide RNAi screen reveals a role for multipass membrane proteins in endosome-to-golgi retrieval. Cell Rep (2014) 0.76
Probing molecular choreography through single-molecule biochemistry. Nat Struct Mol Biol (2015) 0.76
Identification of Extracellular Segments by Mass Spectrometry Improves Topology Prediction of Transmembrane Proteins. Sci Rep (2017) 0.75
Comparison between the behavior of different hydrophobic peptides allowing membrane anchoring of proteins. Adv Colloid Interface Sci (2014) 0.75
A competing hydrophobic tug on L596 to the membrane core unlatches S4-S5 linker elbow from TRP helix and allows TRPV4 channel to open. Proc Natl Acad Sci U S A (2016) 0.75
Micro-scale and rapid expression screening of highly expressed and/or stable membrane protein variants in Saccharomyces cerevisiae. Protein Sci (2016) 0.75
A survey of membrane proteins in human serum. Proteomics Insights (2012) 0.75
Confirmation of translatability and functionality certifies the dual endothelin1/VEGFsp receptor (DEspR) protein. BMC Mol Biol (2016) 0.75
Topology based identification and comprehensive classification of four-transmembrane helix containing proteins (4TMs) in the human genome. BMC Genomics (2016) 0.75
The cellular membrane as a mediator for small molecule interaction with membrane proteins. Biochim Biophys Acta (2016) 0.75
Improved protease digestion conditions for membrane protein detection. Electrophoresis (2015) 0.75
TMSEG: Novel prediction of transmembrane helices. Proteins (2016) 0.75
Membrane potentials regulating GPCRs: insights from experiments and molecular dynamics simulations. Curr Opin Pharmacol (2016) 0.75
Small expression tags enhance bacterial expression of the first three transmembrane segments of the apelin receptor. Biochem Cell Biol (2014) 0.75
Comparative proteomic analysis reveals a dynamic pollen plasma membrane protein map and the membrane landscape of receptor-like kinases and transporters important for pollen tube growth and interaction with pistils in rice. BMC Plant Biol (2017) 0.75
Proteomic Analysis of the Rat Canalicular Membrane Reveals Expression of a Complex System of P4-ATPases in Liver. PLoS One (2016) 0.75
Deorphanizing the human transmembrane genome: A landscape of uncharacterized membrane proteins. Acta Pharmacol Sin (2013) 0.75
Extension of the Highly Mobile Membrane Mimetic to Transmembrane Systems through Customized in Silico Solvents. J Phys Chem B (2017) 0.75
Transverse and tangential orientation of predicted transmembrane fragments 4 and 10 from the human multidrug resistance protein (hMRP1/ABCC1) in membrane mimics. Eur Biophys J (2011) 0.75
Improved prediction of signal peptides: SignalP 3.0. J Mol Biol (2004) 48.40
SignalP 4.0: discriminating signal peptides from transmembrane regions. Nat Methods (2011) 33.90
International network of cancer genome projects. Nature (2010) 20.35
Locating proteins in the cell using TargetP, SignalP and related tools. Nat Protoc (2007) 19.50
Prepublication data sharing. Nature (2009) 12.24
Towards a knowledge-based Human Protein Atlas. Nat Biotechnol (2010) 11.05
Recognition of transmembrane helices by the endoplasmic reticulum translocon. Nature (2005) 7.72
A human protein atlas for normal and cancer tissues based on antibody proteomics. Mol Cell Proteomics (2005) 7.13
A genecentric Human Protein Atlas for expression profiles based on antibodies. Mol Cell Proteomics (2008) 6.45
Molecular code for transmembrane-helix recognition by the Sec61 translocon. Nature (2007) 4.60
Global topology analysis of the Escherichia coli inner membrane proteome. Science (2005) 4.11
Recommendations from the 2008 International Summit on Proteomics Data Release and Sharing Policy: the Amsterdam principles. J Proteome Res (2009) 3.77
Membrane insertion of a potassium-channel voltage sensor. Science (2005) 3.30
Reliability measures for membrane protein topology prediction algorithms. J Mol Biol (2003) 3.13
Identification and evolution of dual-topology membrane proteins. Nat Struct Mol Biol (2006) 3.12
Emulating membrane protein evolution by rational design. Science (2007) 2.96
Interface connections of a transmembrane voltage sensor. Proc Natl Acad Sci U S A (2005) 2.92
Coping with cold: the genome of the versatile marine Antarctica bacterium Pseudoalteromonas haloplanktis TAC125. Genome Res (2005) 2.89
Toward a confocal subcellular atlas of the human proteome. Mol Cell Proteomics (2007) 2.80
Prediction of membrane-protein topology from first principles. Proc Natl Acad Sci U S A (2008) 2.55
Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics. Mol Cell Proteomics (2013) 2.53
Central functions of the lumenal and peripheral thylakoid proteome of Arabidopsis determined by experimentation and genome-wide prediction. Plant Cell (2002) 2.48
A global view of protein expression in human cells, tissues, and organs. Mol Syst Biol (2009) 2.41
Correlations between RNA and protein expression profiles in 23 human cell lines. BMC Genomics (2009) 2.36
The human proteome project: current state and future direction. Mol Cell Proteomics (2011) 2.34
Antibodypedia, a portal for sharing antibody and antigen validation data. Mol Cell Proteomics (2008) 2.34
The genome sequence of Mycoplasma mycoides subsp. mycoides SC type strain PG1T, the causative agent of contagious bovine pleuropneumonia (CBPP). Genome Res (2004) 2.33
Control of membrane protein topology by a single C-terminal residue. Science (2010) 2.28
Membrane protein structure: prediction versus reality. Annu Rev Biochem (2007) 2.21
Rapid topology mapping of Escherichia coli inner-membrane proteins by prediction and PhoA/GFP fusion analysis. Proc Natl Acad Sci U S A (2002) 2.17
High-throughput fluorescent-based optimization of eukaryotic membrane protein overexpression and purification in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2007) 2.15
The biotin-streptavidin interaction can be reversibly broken using water at elevated temperatures. Electrophoresis (2005) 2.12
GFP-based optimization scheme for the overexpression and purification of eukaryotic membrane proteins in Saccharomyces cerevisiae. Nat Protoc (2008) 2.06
Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. Nat Methods (2013) 2.05
A Populus EST resource for plant functional genomics. Proc Natl Acad Sci U S A (2004) 2.04
ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome. Nat Methods (2007) 2.04
How translocons select transmembrane helices. Annu Rev Biophys (2008) 2.03
CXCR4 and cancer. Pathol Int (2010) 1.73
Protein complexes of the Escherichia coli cell envelope. J Biol Chem (2005) 1.69
A study of the membrane-water interface region of membrane proteins. J Mol Biol (2004) 1.68
Evidence for a protein transported through the secretory pathway en route to the higher plant chloroplast. Nat Cell Biol (2005) 1.66
Transmembrane helices before, during, and after insertion. Curr Opin Struct Biol (2005) 1.64
ATP-induced conformational dynamics in the AAA+ motor unit of magnesium chelatase. Structure (2010) 1.63
Biogenesis of inner membrane proteins in Escherichia coli. Annu Rev Microbiol (2005) 1.61
Somatic acquisition and signaling of TGFBR1*6A in cancer. JAMA (2005) 1.59
Arginine in membranes: the connection between molecular dynamics simulations and translocon-mediated insertion experiments. J Membr Biol (2010) 1.58
Poly (ADP-ribose) polymerase (PARP) is not involved in base excision repair but PARP inhibition traps a single-strand intermediate. Nucleic Acids Res (2010) 1.57
The Dominant white, Dun and Smoky color variants in chicken are associated with insertion/deletion polymorphisms in the PMEL17 gene. Genetics (2004) 1.57
Comparative analysis of amino acid distributions in integral membrane proteins from 107 genomes. Proteins (2005) 1.57
Photocross-linking of nascent chains to the STT3 subunit of the oligosaccharyltransferase complex. J Cell Biol (2003) 1.54
Anti-idiotypic protein domains selected from protein A-based affibody libraries. Proteins (2002) 1.52
A nine-transmembrane domain topology for presenilin 1. J Biol Chem (2005) 1.52
Expression of the RNA-binding protein RBM3 is associated with a favourable prognosis and cisplatin sensitivity in epithelial ovarian cancer. J Transl Med (2010) 1.51
Membrane topology of the human seipin protein. FEBS Lett (2006) 1.48
A global topology map of the Saccharomyces cerevisiae membrane proteome. Proc Natl Acad Sci U S A (2006) 1.45
A web-based tool for in silico biomarker discovery based on tissue-specific protein profiles in normal and cancer tissues. Mol Cell Proteomics (2007) 1.43
Molecular recognition of a single sphingolipid species by a protein's transmembrane domain. Nature (2012) 1.42
Topology models for 37 Saccharomyces cerevisiae membrane proteins based on C-terminal reporter fusions and predictions. J Biol Chem (2003) 1.40
Molecular correlates and prognostic significance of SATB1 expression in colorectal cancer. Diagn Pathol (2012) 1.38
Targeting HMG-CoA reductase with statins in a window-of-opportunity breast cancer trial. Breast Cancer Res Treat (2013) 1.38
The machinery of membrane protein assembly. Curr Opin Struct Biol (2004) 1.34
The RBCC gene RFP2 (Leu5) encodes a novel transmembrane E3 ubiquitin ligase involved in ERAD. Mol Biol Cell (2007) 1.33
Expression and subcellular distribution of novel glomerulus-associated proteins dendrin, ehd3, sh2d4a, plekhh2, and 2310066E14Rik. J Am Soc Nephrol (2007) 1.33
Asn- and Asp-mediated interactions between transmembrane helices during translocon-mediated membrane protein assembly. EMBO Rep (2006) 1.33
Insertion of short transmembrane helices by the Sec61 translocon. Proc Natl Acad Sci U S A (2009) 1.31
PONGO: a web server for multiple predictions of all-alpha transmembrane proteins. Nucleic Acids Res (2006) 1.29
Sequence-based feature prediction and annotation of proteins. Genome Biol (2009) 1.28
SATB2 in combination with cytokeratin 20 identifies over 95% of all colorectal carcinomas. Am J Surg Pathol (2011) 1.27
A biphasic pulling force acts on transmembrane helices during translocon-mediated membrane integration. Nat Struct Mol Biol (2012) 1.24
Contribution of hydrophobic and electrostatic interactions to the membrane integration of the Shaker K+ channel voltage sensor domain. Proc Natl Acad Sci U S A (2007) 1.24
Determination of binding specificities in highly multiplexed bead-based assays for antibody proteomics. Mol Cell Proteomics (2006) 1.22
Molecular code for protein insertion in the endoplasmic reticulum membrane is similar for N(in)-C(out) and N(out)-C(in) transmembrane helices. Proc Natl Acad Sci U S A (2008) 1.21
In silico prediction of the peroxisomal proteome in fungi, plants and animals. J Mol Biol (2003) 1.21
Determination of N- and C-terminal borders of the transmembrane domain of integrin subunits. J Biol Chem (2004) 1.21
Extensive linkage disequilibrium in small human populations in Eurasia. Am J Hum Genet (2002) 1.20
Glcci1 deficiency leads to proteinuria. J Am Soc Nephrol (2011) 1.19
Automated Analysis of Human Protein Atlas Immunofluorescence Images. Proc IEEE Int Symp Biomed Imaging (2009) 1.18
Epitope mapping of antibodies using bacterial surface display. Nat Methods (2008) 1.18
Functionality of the voltage-gated proton channel truncated in S4. Proc Natl Acad Sci U S A (2009) 1.18
Membrane topology mapping of vitamin K epoxide reductase by in vitro translation/cotranslocation. J Biol Chem (2005) 1.17
Detection and analysis of low-abundance cell-surface biomarkers using enzymatic amplification in microfluidic droplets. Angew Chem Int Ed Engl (2009) 1.17
Validation of podocalyxin-like protein as a biomarker of poor prognosis in colorectal cancer. BMC Cancer (2012) 1.17
Tumour-specific HMG-CoAR is an independent predictor of recurrence free survival in epithelial ovarian cancer. BMC Cancer (2010) 1.17
RBM3-regulated genes promote DNA integrity and affect clinical outcome in epithelial ovarian cancer. Transl Oncol (2011) 1.16
Affinity proteomics for systematic protein profiling of chromosome 21 gene products in human tissues. Mol Cell Proteomics (2003) 1.15
Phenotypic effects of membrane protein overexpression in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2006) 1.15
Low RBM3 protein expression correlates with tumour progression and poor prognosis in malignant melanoma: an analysis of 215 cases from the Malmö Diet and Cancer Study. J Transl Med (2011) 1.15
Experimentally constrained topology models for 51,208 bacterial inner membrane proteins. J Mol Biol (2005) 1.14
Sun1 forms immobile macromolecular assemblies at the nuclear envelope. Biochim Biophys Acta (2008) 1.12
A community standard format for the representation of protein affinity reagents. Mol Cell Proteomics (2009) 1.11
Contribution of antibody-based protein profiling to the human Chromosome-centric Proteome Project (C-HPP). J Proteome Res (2012) 1.11
Disulfide bond formation and cysteine exclusion in gram-positive bacteria. J Biol Chem (2009) 1.09
Antibody suspension bead arrays within serum proteomics. J Proteome Res (2008) 1.08
Membrane insertion of marginally hydrophobic transmembrane helices depends on sequence context. J Mol Biol (2009) 1.07
Membrane topology of the STT3 subunit of the oligosaccharyl transferase complex. J Biol Chem (2005) 1.05
Microbead display of proteins by cell-free expression of anchored DNA. J Biotechnol (2003) 1.04
Endogenous gene and protein expression of drug-transporting proteins in cell lines routinely used in drug discovery programs. Drug Metab Dispos (2009) 1.02
A whole-genome bioinformatics approach to selection of antigens for systematic antibody generation. Proteomics (2008) 1.01