Ichiro Katayama

Author PubWeight™ 102.13‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+ regulatory T cells, evoking antitumor immune responses in humans. Proc Natl Acad Sci U S A 2013 2.47
2 Artemin causes hypersensitivity to warm sensation, mimicking warmth-provoked pruritus in atopic dermatitis. J Allergy Clin Immunol 2012 2.15
3 Guidelines for management of atopic dermatitis. J Dermatol 2009 1.54
4 A case of juvenile dermatomyositis manifesting inflammatory epidermal nevus-like skin lesions: unrecognized cutaneous manifestation of blaschkitis? Allergol Int 2010 1.46
5 Towards global consensus on outcome measures for atopic eczema research: results of the HOME II meeting. Allergy 2012 1.41
6 PDGFRalpha-positive cells in bone marrow are mobilized by high mobility group box 1 (HMGB1) to regenerate injured epithelia. Proc Natl Acad Sci U S A 2011 1.38
7 Semaphorins guide the entry of dendritic cells into the lymphatics by activating myosin II. Nat Immunol 2010 1.33
8 Dickkopf 1 (DKK1) regulates skin pigmentation and thickness by affecting Wnt/beta-catenin signaling in keratinocytes. FASEB J 2007 1.29
9 Olmsted syndrome with squamous cell carcinoma of extremities and adenocarcinoma of the lung: failure to detect loricrin gene mutation. Eur J Dermatol 2004 1.22
10 Trends in the prevalence of tuberous sclerosis complex manifestations: an epidemiological study of 166 Japanese patients. PLoS One 2013 1.15
11 The skin of patients with systemic sclerosis softened during the treatment with anti-IL-6 receptor antibody tocilizumab. Rheumatology (Oxford) 2010 1.08
12 A randomized double-blind trial of intravenous immunoglobulin for pemphigus. J Am Acad Dermatol 2009 1.06
13 Periostin facilitates skin sclerosis via PI3K/Akt dependent mechanism in a mouse model of scleroderma. PLoS One 2012 1.05
14 Steady state migratory RelB+ langerin+ dermal dendritic cells mediate peripheral induction of antigen-specific CD4+ CD25+ Foxp3+ regulatory T cells. Eur J Immunol 2011 1.03
15 Induction of beta-defensin 3 in keratinocytes stimulated by bacterial lipopeptides through toll-like receptor 2. Microbes Infect 2006 1.01
16 Japanese cedar pollen as an exacerbation factor in atopic dermatitis: results of atopy patch testing and histological examination. Acta Derm Venereol 2006 1.00
17 Dysregulation of melanocyte function by Th17-related cytokines: significance of Th17 cell infiltration in autoimmune vitiligo vulgaris. Pigment Cell Melanoma Res 2012 0.98
18 Interstitial type granuloma annulare associated with Sjögren's syndrome. J Dermatol 2010 0.98
19 Blockade of interleukin-6 receptor alleviates disease in mouse model of scleroderma. Am J Pathol 2011 0.98
20 Differential regulation of karyopherin alpha 2 expression by TGF-beta1 and IFN-gamma in normal human epidermal keratinocytes: evident contribution of KPNA2 for nuclear translocation of IRF-1. J Invest Dermatol 2007 0.97
21 Mesenchymal-epithelial interactions in the skin: aiming for site-specific tissue regeneration. J Dermatol Sci 2005 0.97
22 A novel application of topical rapamycin formulation, an inhibitor of mTOR, for patients with hypomelanotic macules in tuberous sclerosis complex. Arch Dermatol 2012 0.97
23 Periostin, a matricellular protein, accelerates cutaneous wound repair by activating dermal fibroblasts. Exp Dermatol 2012 0.96
24 Enhanced epithelial-mesenchymal transition-like phenotype in N-acetylglucosaminyltransferase V transgenic mouse skin promotes wound healing. J Biol Chem 2011 0.93
25 Nodular scleroderma: increased expression of connective tissue growth factor. Dermatology 2005 0.93
26 Dosage and adverse effects of topical tacrolimus and steroids in daily management of atopic dermatitis. J Dermatol 2004 0.92
27 AMP kinase-related kinase NUAK2 affects tumor growth, migration, and clinical outcome of human melanoma. Proc Natl Acad Sci U S A 2011 0.92
28 Disseminated granuloma annulare responsive to narrowband ultraviolet B therapy. J Am Acad Dermatol 2005 0.91
29 11β-Hydroxysteroid dehydrogenase-1 is a novel regulator of skin homeostasis and a candidate target for promoting tissue repair. PLoS One 2011 0.91
30 Periostin accelerates human malignant melanoma progression by modifying the melanoma microenvironment. Pigment Cell Melanoma Res 2014 0.90
31 Generalized lichen nitidus in Russell-Silver syndrome. Pediatr Dermatol 2012 0.90
32 Nodal lymphangiogenesis and metastasis: Role of tumor-induced lymphatic vessel activation in extramammary Paget's disease. Am J Pathol 2009 0.90
33 Atopic diathesis in hypohidrotic/anhidrotic ectodermal dysplasia. Acta Derm Venereol 2015 0.90
34 Improvement of recurrent urticaria in a patient with Schnitzler syndrome associated with B-cell lymphoma with combination rituximab and radiotherapy. J Am Acad Dermatol 2009 0.89
35 Airborne contact dermatitis due to Japanese cedar pollen. Contact Dermatitis 2007 0.89
36 Intractable wounds caused by calcific uremic arteriolopathy treated with bisphosphonates. J Am Acad Dermatol 2007 0.89
37 Nonsegmental vitiligo and autoimmune mechanism. Dermatol Res Pract 2011 0.89
38 Developing core outcome set for vitiligo clinical trials: international e-Delphi consensus. Pigment Cell Melanoma Res 2015 0.89
39 Urticarial reaction caused by ethanol. Allergol Int 2006 0.88
40 Tumor necrosis factor-alpha processing inhibitor-1 inhibits skin fibrosis in a bleomycin-induced murine model of scleroderma. Exp Dermatol 2009 0.88
41 Expression profiles of cortisol-inactivating enzyme, 11β-hydroxysteroid dehydrogenase-2, in human epidermal tumors and its role in keratinocyte proliferation. Exp Dermatol 2013 0.87
42 Pilomatrix carcinoma arising from pilomatricoma after 10-year senescent period: Immunohistochemical analysis. J Dermatol 2010 0.87
43 Identification of semaphorin 4B as a negative regulator of basophil-mediated immune responses. J Immunol 2011 0.87
44 Both CD4+ and CD8+ T cell epitopes fused to heat shock cognate protein 70 (hsc70) can function to eradicate tumors. Cancer Sci 2008 0.87
45 Development and clinical study of a self-dissolving microneedle patch for transcutaneous immunization device. Pharm Res 2013 0.87
46 Impact of sedative and non-sedative antihistamines on the impaired productivity and quality of life in patients with pruritic skin diseases. Allergol Int 2010 0.86
47 Prevalence and impact of past history of food allergy in atopic dermatitis. Allergol Int 2012 0.86
48 Autoantibodies to IgG/HLA class II complexes are associated with rheumatoid arthritis susceptibility. Proc Natl Acad Sci U S A 2014 0.86
49 Serum anti-BPAG1 auto-antibody is a novel marker for human melanoma. PLoS One 2010 0.86
50 Granulomatous cheilitis successfully treated with roxithromycin. J Dermatol 2008 0.85
51 Abnormal axon reflex-mediated sweating correlates with high state of anxiety in atopic dermatitis. Allergol Int 2012 0.84
52 Psoriatic arthritis in two patients with an inadequate response to treatment with tocilizumab. Joint Bone Spine 2011 0.84
53 Factors associated with the development and remission of allergic diseases in an epidemiological survey of high school students in Japan. Am J Rhinol Allergy 2015 0.84
54 Four cases of atopic dermatitis complicated by Sjögren's syndrome: link between dry skin and autoimmune anhidrosis. Allergol Int 2011 0.84
55 Nerve growth factor (NGF) and epidermal nerve fibers in atopic dermatitis model NC/Nga mice. J Dermatol Sci 2005 0.83
56 Case of morphea occurring on a scar after laparoscopy. J Dermatol 2006 0.83
57 Intractable wounds caused by arteriosclerosis obliterans with end-stage renal disease treated by aggressive debridement and epidermal grafting. J Am Acad Dermatol 2007 0.83
58 Intractable wounds from a herpes simplex infection in an immunosuppressed patient with rheumatoid arthritis. Arch Dermatol 2007 0.83
59 Severe dermatitis with loss of epidermal Langerhans cells in human and mouse zinc deficiency. J Clin Invest 2012 0.83
60 Two novel mutations in the ED1 gene in Japanese families with X-linked hypohidrotic ectodermal dysplasia. Pediatr Res 2009 0.82
61 11β-Hydroxysteroid dehydrogenase 1 contributes to the pro-inflammatory response of keratinocytes. Biochem Biophys Res Commun 2013 0.81
62 Decreased sudomotor function is involved in the formation of atopic eczema in the cubital fossa. Allergol Int 2013 0.81
63 Characterization of dsRNA-induced pancreatitis model reveals the regulatory role of IFN regulatory factor 2 (Irf2) in trypsinogen5 gene transcription. Proc Natl Acad Sci U S A 2011 0.81
64 Pigmented epithelioid melanocytoma with lymph node metastasis in a patient with uncontrolled atopic dermatitis. J Dermatol 2014 0.81
65 Vascular changes in bleomycin-induced scleroderma. Int J Rheumatol 2011 0.81
66 IFN-γ or IFN-α ameliorates chronic proliferative dermatitis by inducing expression of linear ubiquitin chain assembly complex. J Immunol 2014 0.81
67 [Skin symptoms in Yusho patients related to blood dioxin level]. Fukuoka Igaku Zasshi 2005 0.81
68 New aspect of anti-inflammatory action of lipo-prostaglandinE1 in the management of collagen diseases-related skin ulcer. Rheumatol Int 2008 0.81
69 Establishment of suction blister roof grafting by injection of local anesthesia beneath the epidermis: less painful and more rapid formation of blisters. J Dermatol Sci 2008 0.81
70 Venous insufficiency in patients with necrobiosis lipoidica. J Dermatol 2009 0.81
71 Epithelioid angiosarcoma of the skin with spontaneous regression. J Dermatol 2013 0.81
72 Unusual erythemas with eosinophilia, caused by H2-blocker famotidine in a male patient with glioblastoma. J Dermatol 2004 0.80
73 Substance P induced preprotachykinin-a mRNA, neutral endopeptidase mRNA and substance P in cultured normal fibroblasts. Int Arch Allergy Immunol 2002 0.80
74 Anti-tumor effects of inactivated Sendai virus particles with an IL-2 gene on angiosarcoma. Clin Immunol 2013 0.80
75 Case of schwannomatosis. J Dermatol 2009 0.80
76 Barrier abnormality due to ceramide deficiency leads to psoriasiform inflammation in a mouse model. J Invest Dermatol 2013 0.80
77 Showering reduces atopic dermatitis in elementary school students. Eur J Dermatol 2010 0.80
78 Alopecia areata: infiltration of Th17 cells in the dermis, particularly around hair follicles. Dermatology 2013 0.80
79 Upregulation of N-acetylglucosaminyltransferase-V by heparin-binding EGF-like growth factor induces keratinocyte proliferation and epidermal hyperplasia. Exp Dermatol 2012 0.79
80 Guidelines for the diagnosis and treatment of vitiligo in Japan. J Dermatol 2013 0.79
81 Topical application of rapamycin ointment ameliorates Dermatophagoides farina body extract-induced atopic dermatitis in NC/Nga mice. Exp Dermatol 2014 0.79
82 Olopatadine hydrochloride improves dermatitis score and inhibits scratch behavior in NC/Nga mice. Int Arch Allergy Immunol 2010 0.79
83 Simultaneous occurrence of dermatomyositis and systemic sarcoidosis with recurrent breast cancer. J Dermatol 2011 0.78
84 A case of bullous pemphigoid arising in juvenile hyaline fibromatosis with oral squamous cell carcinoma. J Dermatol 2005 0.78
85 Vaccination with WT-1 (Wilms' tumor gene-1) peptide and BCG-CWS in melanoma. Eur J Dermatol 2012 0.78
86 A case of disseminated DLE complicated by atopic dermatitis and Sjögren's syndrome: link between hypohidrosis and skin manifestations. Mod Rheumatol 2010 0.78
87 Fas-mediated apoptosis of melanoma cells and infiltrating lymphocytes in human malignant melanomas. Mod Pathol 2002 0.78
88 Uncontrollable prurigo nodularis effectively treated by roxithromycin and tranilast. J Drugs Dermatol 2006 0.78
89 Lipoteichoic acid-related molecule derived from the streptococcal preparation, OK-432, which suppresses atopic dermatitis-like lesions in NC/Nga mice. Arch Dermatol Res 2006 0.78
90 Cedar pollen aggravates atopic dermatitis in childhood monozygotic twin patients with allergic rhino conjunctivitis. Allergol Int 2011 0.78
91 Toxic epidermal necrolysis complicated by sepsis, haemophagocytic syndrome, and severe liver dysfunction associated with elevated interleukin-10 production. Eur J Dermatol 2012 0.78
92 Isolation and characterization of sweat gland myoepithelial cells from human skin. Cell Struct Funct 2014 0.77
93 Guide for medical professionals (i.e., dermatologists) for the management of Rhododenol-induced leukoderma. J Dermatol 2015 0.77
94 T helper 2 polarization in senile erythroderma with elevated levels of TARC and IgE. Dermatology 2015 0.77
95 Therapeutic effects of streptococcal preparation OK-432 on atopic dermatitis-like lesions in NC/Nga mice: possible shift from a Th2- to Th1-predominance. J Dermatol Sci 2004 0.77
96 Role of mast cells in dermatofibroma: recent viewpoints into the pathogenesis. Eur J Dermatol 2003 0.77
97 Good's syndrome (hypogammaglobulinemia with thymoma) presenting intractable opportunistic infections and hyperkeratotic lichen planus. J Dermatol 2010 0.77
98 The predominant drug-specific T-cell population may switch from cytotoxic T cells to regulatory T cells during the course of anticonvulsant-induced hypersensitivity. J Dermatol Sci 2011 0.77
99 Disruption of tumor necrosis factor receptor p55 impairs collagen turnover in experimentally induced sclerodermic skin fibroblasts. Arthritis Rheum 2003 0.77
100 Adult case of Stevens-Johnson syndrome possibly induced by Chlamydophila pneumoniae infection with severe involvement of bronchial epithelium resulting in constructive respiratory disorder. J Dermatol 2013 0.77
101 Emedastine difumarate: a review of its potential ameliorating effect for tissue remodeling in allergic diseases. Expert Opin Pharmacother 2009 0.77
102 Systemic allergic contact dermatitis to palladium inlay manifesting as annular erythema. Eur J Dermatol 2012 0.76
103 Assessment of antihistamines in the treatment of skin allergies. Curr Opin Allergy Clin Immunol 2011 0.76
104 [Survey of atopic dermatitis and skin barrier functions in Japanese and Chinese school students]. Arerugi 2007 0.76
105 Palpebral edema as a cutaneous manifestation of hyperthyroidism. J Am Acad Dermatol 2003 0.76
106 Olopatadine hydrochloride decreases tissue interleukin-31 levels in an atopic dermatitis mouse model. Acta Derm Venereol 2014 0.76
107 Clinical effect of tocoretinate on lichen and macular amyloidosis. J Dermatol 2010 0.76
108 Localized argyria 20-years after embedding of acupuncture needles. Eur J Dermatol 2002 0.76
109 Karyopherin alpha2 is essential for rRNA transcription and protein synthesis in proliferative keratinocytes. PLoS One 2013 0.76
110 The induction of heme oxygenase-1 by exogenous nitric oxide in ex vivo normal human skin. J Dermatol 2003 0.75
111 Morphea on the breast after a needle biopsy. Ann Dermatol 2011 0.75
112 Peculiar distribution of tumorous xanthomas in an adult case of erdheim-chester disease complicated by atopic dermatitis. Case Rep Dermatol 2011 0.75
113 Vitiligo exacerbated after herpes zoster. J Dermatol 2012 0.75
114 A case of giant squamous cell carcinoma of the buttock possibly arose from syringocystadenoma and invaded to the rectum. J Skin Cancer 2010 0.75
115 Serum concentration of nitric oxide in Yusho patients over 30 years after the accidental poisoning of polychlorinated biphenyls in Japan. Toxicol Ind Health 2002 0.75
116 Novel functional aspect of antihistamines: the impact of bepotastine besilate on substance p-induced events. J Allergy (Cairo) 2009 0.75
117 Atypical pemphigus involving the esophagus with IgG antibodies to desmoglein 3 and IgA antibodies to desmoglein 1. J Am Acad Dermatol 2006 0.75
118 Serum antioxidant levels in Yusho victims over 30 years after the accidental poisoning of polychlorinated biphenyls in Nagasaki, Japan. Toxicol Ind Health 2003 0.75
119 Effective oral psoralen plus ultraviolet a therapy for digital ulcers with revascularization in systemic sclerosis. Acta Derm Venereol 2014 0.75
120 Reply: To PMID 22770266. J Allergy Clin Immunol 2013 0.75
121 Massive cutaneous follicular lymphoid hyperplasia in a patient with the Sjögren syndrome: 7-year follow-up and immunohistochemical study. Rheumatol Int 2006 0.75
122 Evaluation of the clinical safety and efficacy of a newly developed 308-nm excimer lamp for vitiligo vulgaris. J Dermatol 2011 0.75
123 Case of tuberous sclerosis complex complicated by mosaic localized neurofibromatosis type 1. J Dermatol 2013 0.75
124 [Examination of "areas cutanea" in Yusho patients]. Fukuoka Igaku Zasshi 2003 0.75
125 Olecranon Osteomyelitis Caused by Mycobacterium chelonae. Intern Med 2016 0.75
126 Two cases of refractory discoid lupus erythematosus successfully treated with topical tocoretinate. Dermatol Online J 2011 0.75
127 Eosinophil infiltration in three patients with generalized atrophic benign epidermolysis bullosa from a Japanese family: molecular genetic and immunohistochemical studies. J Hum Genet 2005 0.75
128 Non-pigmenting fixed drug eruption caused by an over-the-counter non-steroidal anti-inflammatory drug: drug-specific CD8+ T lymphocytes identified in peripheral blood. Eur J Dermatol 2012 0.75
129 Spontaneous IL-8 production by CD4(+), CD7(+) leukemia cells in erythrodermic Sézary syndrome. Leuk Lymphoma 2002 0.75
130 Consumption of the epidermis in acral lentiginous melanoma. J Cutan Pathol 2012 0.75
131 Successful treatment with regimen of intravenous gamma globulin and cyclophosphamide for dermatomyositis accompanied by interstitial pneumonia, opportunistic infection and steroid psychosis. Allergol Int 2006 0.75
132 Role of macrophage infiltration in successful repigmentation in a new periphery-spreading vitiligo lesion in a male Japanese patient. J Dermatol 2013 0.75
133 Clinical implications of leukocytapheresis using a centrifugal cell separator for steroid-resistant pyoderma gangrenosum associated with inflammatory bowel disease. J Dermatol 2010 0.75
134 Allergic contact dermatitis induced by rosemary leaf extract in a cleansing gel. J Dermatol 2005 0.75
135 Allergic contact dermatitis due to external bone lengthener. J Dermatol 2009 0.75
136 Repigmentation of leukoderma in a piebald patient associated with a novel c-KIT gene mutation, G592E, of the tyrosine kinase domain. J Dermatol Sci 2011 0.75
137 [Hypersensitivity reactions to multiple drugs during the course of hairy cell leukemia treated with 2-chlorodeoxyadenosine]. Arerugi 2006 0.75
138 Blaschkitis-like eruptions with hypodontia and low IκB kinase gamma expression. J Dermatol 2012 0.75
139 Stage III melanoma treated with chemotherapy after surgery during the second trimester of pregnancy. Arch Dermatol 2009 0.75
140 Topical cholesterol treatment ameliorates hapten-evoked cutaneous hypersensitivity by sustaining expression of 11β-HSD1 in epidermis. Exp Dermatol 2014 0.75
141 Loss of heterozygosity on chromosome 9q22.3 in microdissected basal cell carcinomas around the Semipalatinsk Nuclear Testing Site, Kazakhstan. Hum Pathol 2004 0.75
142 Etanercept is safely used for treating psoriatic arthritis in a patient complicated with type 1 hereditary angioedema. Mod Rheumatol 2012 0.75
143 Severe scoliosis associated with the WNT10A mutation. J Dermatol 2015 0.75
144 Eosinophilic pyoderma gangrenosum with pulmonary and oral lesions preceded by eosinophilic pneumonia: Unrecognized syndromic manifestations? Eur J Dermatol 2011 0.75
145 Alopecia universalis associated with Zumbusch-type generalized pustular psoriasis. Dermatology 2002 0.75
146 Intractable wounds caused by pyoderma gangrenosum in a patient with critical limb ischemia treated with cyclosporine and adjuvant sympathectomy. Dermatol Surg 2009 0.75
147 Suplatast tosilate inhibits eosinophil production and recruitment into the skin in murine contact sensitivity. Clin Immunol 2003 0.75
148 Idiopathic pure sudomotor failure responding to oral antihistamine with sweating activities. Acta Derm Venereol 2014 0.75
149 Case of Behçet's disease complicated by oculomotor nerve palsy associated with internal carotid artery-posterior communicating artery aneurysm. J Dermatol 2015 0.75
150 Superimposed linear psoriasis. J Dermatol 2010 0.75
151 Systemic sclerosis with sarcoidosis: case report and review of the published work. J Dermatol 2014 0.75
152 Severe rosacea with prominent Demodex folliculorum in a patient with HIV. J Dermatol 2014 0.75
153 Positive link between STAT3 activation and Th17 cell infiltration to the lesional skin in vitiligo vulgaris. J Dermatol Sci 2012 0.75
154 Dissociate expression of tuberous sclerosis complex 1 product hamartin in a skin and pulmonary lesion of a tuberous sclerosis complex. Hum Pathol 2008 0.75
155 [Case of urticaria due to cochineal dye in red-colored diet]. Arerugi 2007 0.75
156 Suplatast/tacrolimus combination therapy for refractory facial erythema in adult patients with atopic dermatitis: a meta-analysis study. Allergol Int 2007 0.75
157 [NFkappaB decoy DNA for treatment of atopic dermatitis]. Nihon Rinsho 2005 0.75
158 Seven cases of vitiligo complicated by atopic dermatitis: suggestive new spectrum of autoimmune vitiligo. Eur J Dermatol 2012 0.75
159 A Male Patient with Humoral Hypercalcemia of Malignancy (HHM) with Leukocytosis Caused by Cutaneous Squamous Cell Carcinoma Resulting from Recessive Dystrophic Epidermolysis Bullosa. Clin Pediatr Endocrinol 2011 0.75
160 An extremely rare case of Merkel cell carcinoma metastasized to the duodenum. Eur J Dermatol 2012 0.75
161 Lichen aureus responding to topical tacrolimus treatment. J Dermatol 2010 0.75
162 Acute generalized exanthematous pustulosis induced by topical diphenhydramine. Eur J Dermatol 2012 0.75
163 Pro-inflammatory cytokine IL-1alpha potential for tissue repair in chemically and mechanically induced injury in cultured human keratinocytes. J Dermatol Sci 2004 0.75
164 [Diagnostic approach based on physiopathology. 3. Atopic dermatitis]. Nihon Naika Gakkai Zasshi 2004 0.75
165 Histamine Modulates Sweating and Affects Clinical Manifestations of Atopic Dermatitis. Curr Probl Dermatol 2016 0.75
166 Lichen planus-type chronic graft-versus-host disease complicated by mucous membrane pemphigoid with positive anti-BP180/230 and scleroderma-related autoantibodies followed by reduced regulatory T cell frequency. Eur J Dermatol 2012 0.75
167 Hepatitis C-related mixed type vitiligo in a patient with Ivemark syndrome. J Dermatol 2014 0.75
168 Systemic lymphadenopathy with systemic sclerosis and Sjögren's syndrome: a case report. J Dermatol 2012 0.75
169 Heat-inductible turbidity precipitates in plasma samples of livedo reticularis with summer ulceration: hypothesis for abnormal coagulation in summer. Thromb Haemost 2005 0.75
170 Topical glucocorticoid augments scratching behaviour in dinitrofluorobenzene-sensitized mice by the induction of substance P. Exp Dermatol 2004 0.75
171 Does drug-induced hypersensitivity syndrome elicit bullous pemphigoid? Allergol Int 2008 0.75
172 Development of necrotising fasciitis in a patient treated for rheumatoid arthritis with tocilizumab. Acta Derm Venereol 2015 0.75