|
1
|
Cardiovascular effects of systemic nitric oxide synthase inhibition with asymmetrical dimethylarginine in humans.
|
Circulation
|
2003
|
2.12
|
|
2
|
Asymmetric dimethylarginine in response to recombinant tissue-type plasminogen activator and erythropoietin in acute stroke.
|
Stroke
|
2013
|
2.07
|
|
3
|
Asymmetric dimethylarginine and progression of chronic kidney disease: the mild to moderate kidney disease study.
|
J Am Soc Nephrol
|
2005
|
2.00
|
|
4
|
ADMA increases arterial stiffness and decreases cerebral blood flow in humans.
|
Stroke
|
2006
|
1.88
|
|
5
|
ADMA and oxidative stress are responsible for endothelial dysfunction in hyperhomocyst(e)inemia: effects of L-arginine and B vitamins.
|
Cardiovasc Res
|
2003
|
1.78
|
|
6
|
Marked increase of asymmetric dimethylarginine in patients with incipient primary chronic renal disease.
|
J Am Soc Nephrol
|
2002
|
1.70
|
|
7
|
Asymmetric dimethylarginine, blood pressure, and renal perfusion in elderly subjects.
|
Circulation
|
2003
|
1.63
|
|
8
|
Pharmacokinetics and total elimination of meropenem and vancomycin in intensive care unit patients undergoing extended daily dialysis.
|
Crit Care Med
|
2006
|
1.51
|
|
9
|
Asymmetrical dimethylarginine in idiopathic pulmonary arterial hypertension.
|
Arterioscler Thromb Vasc Biol
|
2005
|
1.32
|
|
10
|
Circulating angiopoietin-2 levels increase with progress of chronic kidney disease.
|
Nephrol Dial Transplant
|
2010
|
1.08
|
|
11
|
Fast and efficient determination of arginine, symmetric dimethylarginine, and asymmetric dimethylarginine in biological fluids by hydrophilic-interaction liquid chromatography-electrospray tandem mass spectrometry.
|
Clin Chem
|
2005
|
1.00
|
|
12
|
Elevated plasma asymmetric dimethyl-L-arginine levels are linked to endothelial progenitor cell depletion and carotid atherosclerosis in rheumatoid arthritis.
|
Arthritis Rheum
|
2007
|
0.99
|
|
13
|
Efficacy profiles of daptomycin for treatment of invasive and noninvasive pulmonary infections with Streptococcus pneumoniae.
|
Antimicrob Agents Chemother
|
2009
|
0.98
|
|
14
|
Therapeutic serum concentrations of daptomycin after intraperitoneal administration in a patient with peritoneal dialysis-associated peritonitis.
|
J Antimicrob Chemother
|
2010
|
0.95
|
|
15
|
The impact of rapid atrial pacing on ADMA and endothelial NOS.
|
Int J Cardiol
|
2010
|
0.92
|
|
16
|
Simultaneous detection of arginine, asymmetric dimethylarginine, symmetric dimethylarginine and citrulline in human plasma and urine applying liquid chromatography-mass spectrometry with very straightforward sample preparation.
|
J Chromatogr B Analyt Technol Biomed Life Sci
|
2003
|
0.90
|
|
17
|
Endothelial dysfunction in patients with peripheral arterial disease and chronic hyperhomocysteinemia: potential role of ADMA.
|
Vasc Med
|
2004
|
0.90
|
|
18
|
Effect of telmisartan on nitric oxide--asymmetrical dimethylarginine system: role of angiotensin II type 1 receptor gamma and peroxisome proliferator activated receptor gamma signaling during endothelial aging.
|
Hypertension
|
2008
|
0.90
|
|
19
|
Esomeprazole-induced rhabdomyolysis in a patient with heart failure.
|
Intensive Care Med
|
2010
|
0.89
|
|
20
|
Validated high performance liquid chromatography-UV detection method for the determination of daptomycin in human plasma.
|
J Chromatogr B Analyt Technol Biomed Life Sci
|
2008
|
0.89
|
|
21
|
Paradoxical effect of L-arginine: acceleration of endothelial cell senescence.
|
Biochem Biophys Res Commun
|
2009
|
0.89
|
|
22
|
Symmetrical dimethylarginine outperforms CKD-EPI and MDRD-derived eGFR for the assessment of renal function in patients with adult congenital heart disease.
|
Kidney Blood Press Res
|
2010
|
0.88
|
|
23
|
Erythropoietin increases asymmetric dimethylarginine in endothelial cells: role of dimethylarginine dimethylaminohydrolase.
|
J Am Soc Nephrol
|
2005
|
0.88
|
|
24
|
Chromatographic-mass spectrometric methods for the quantification of L-arginine and its methylated metabolites in biological fluids.
|
J Chromatogr B Analyt Technol Biomed Life Sci
|
2006
|
0.87
|
|
25
|
Unilateral nephrectomy causes an abrupt increase in inflammatory mediators and a simultaneous decrease in plasma ADMA: a study in living kidney donors.
|
Am J Physiol Renal Physiol
|
2011
|
0.87
|
|
26
|
SDMA is an early marker of change in GFR after living-related kidney donation.
|
Nephrol Dial Transplant
|
2010
|
0.87
|
|
27
|
Determination of asymmetric dimethylarginine: liquid chromatography-mass spectrometry or ELISA?
|
Clin Chem
|
2005
|
0.86
|
|
28
|
Endothelial dysfunction of the peripheral vascular bed in the acute phase after ischemic stroke.
|
Cerebrovasc Dis
|
2011
|
0.86
|
|
29
|
Asymmetric dimethylarginine: a cardiovascular risk factor in renal disease?
|
Kidney Int Suppl
|
2003
|
0.86
|
|
30
|
Decreased meropenem levels in Intensive Care Unit patients with augmented renal clearance: benefit of therapeutic drug monitoring.
|
Int J Antimicrob Agents
|
2012
|
0.86
|
|
31
|
Asymmetrical dimethylarginine--more sensitive than NT-proBNP to diagnose heart failure in adults with congenital heart disease.
|
PLoS One
|
2012
|
0.85
|
|
32
|
Endogenous nitric oxide synthesis inhibitor asymmetric dimethyl L-arginine accelerates endothelial cell senescence.
|
Arterioscler Thromb Vasc Biol
|
2004
|
0.85
|
|
33
|
Determination of arginine and asymmetric dimethylarginine (ADMA) in human plasma by liquid chromatography/mass spectrometry with the isotope dilution technique.
|
J Mass Spectrom
|
2004
|
0.84
|
|
34
|
Plasma levels of asymmetric dimethylarginine in premature neonates: its possible involvement in developmental programming of chronic diseases.
|
Acta Paediatr
|
2008
|
0.84
|
|
35
|
Quantification of L-arginine, asymmetric dimethylarginine and symmetric dimethylarginine in human plasma: a step improvement in precision by stable isotope dilution mass spectrometry.
|
J Chromatogr B Analyt Technol Biomed Life Sci
|
2012
|
0.84
|
|
36
|
Birth by cesarean section is associated with elevated neonatal plasma levels of dimethylarginines.
|
Pediatr Int
|
2012
|
0.83
|
|
37
|
Physiologic and pathophysiologic role of calpain: implications for the occurrence of atrial fibrillation.
|
Cardiovasc Ther
|
2010
|
0.83
|
|
38
|
Nontraditional atherosclerotic risk factors and extent of coronary atherosclerosis in patients with combined impaired fasting glucose and impaired glucose tolerance.
|
Metabolism
|
2007
|
0.83
|
|
39
|
Stent placement in patients with coronary heart disease decreases plasma levels of the endogenous nitric oxide synthase inhibitor ADMA.
|
Int J Mol Med
|
2009
|
0.82
|
|
40
|
Asymmetric dimethylarginine may mediate increased heat pain threshold in experimental chronic kidney disease.
|
Nephrol Dial Transplant
|
2011
|
0.81
|
|
41
|
In vivo evidence that Agxt2 can regulate plasma levels of dimethylarginines in mice.
|
Biochem Biophys Res Commun
|
2012
|
0.81
|
|
42
|
Determination of levetiracetam in human plasma with minimal sample pretreatment.
|
J Chromatogr B Analyt Technol Biomed Life Sci
|
2005
|
0.81
|
|
43
|
Hypercholesterolemia impairs basal nitric oxide synthase turnover rate: a study investigating the conversion of L-[guanidino-(15)N(2)]-arginine to (15)N-labeled nitrate by gas chromatography--mass spectrometry.
|
Nitric Oxide
|
2004
|
0.81
|
|
44
|
Detection and quantification of α-keto-δ-(N(G),N(G)-dimethylguanidino)valeric acid: a metabolite of asymmetric dimethylarginine.
|
Anal Biochem
|
2011
|
0.81
|
|
45
|
Determination of micafungin and anidulafungin in human plasma: UV- or mass spectrometric quantification?
|
J Chromatogr B Analyt Technol Biomed Life Sci
|
2011
|
0.80
|
|
46
|
L-arginine metabolism in early-onset and late-onset pre-eclamptic pregnancies.
|
Scand J Clin Lab Invest
|
2013
|
0.80
|
|
47
|
Effect of L-arginine on asymmetric dimethylarginine (ADMA) or homocysteine-accelerated endothelial cell aging.
|
Biochem Biophys Res Commun
|
2006
|
0.80
|
|
48
|
Plasma asymmetric dimethylarginine is related to anticitrullinated protein antibodies in rheumatoid arthritis of short duration.
|
Metabolism
|
2009
|
0.80
|
|
49
|
Determination of ornithine in human plasma by hydrophilic interaction chromatography-tandem mass spectrometry.
|
J Chromatogr B Analyt Technol Biomed Life Sci
|
2007
|
0.79
|
|
50
|
Asymmetric dimethylarginine predicts appropriate implantable cardioverter-defibrillator intervention in patients with left ventricular dysfunction.
|
Europace
|
2011
|
0.79
|
|
51
|
Association of dimethylarginines and mediators of inflammation after acute ischemic stroke.
|
J Neuroinflammation
|
2012
|
0.79
|
|
52
|
Red wine decreases asymmetric dimethylarginine via SIRT1 induction in human endothelial cells.
|
Biochem Biophys Res Commun
|
2009
|
0.79
|
|
53
|
Pharmacokinetics of moxifloxacin in patients with severe sepsis or septic shock.
|
Intensive Care Med
|
2010
|
0.79
|
|
54
|
L-Arginine, ADMA, SDMA, creatinine, MDRD formula: detour to renal function testing.
|
J Nephrol
|
2008
|
0.79
|
|
55
|
Determination of cerebrospinal fluid concentrations of arginine and dimethylarginines in patients with subarachnoid haemorrhage.
|
J Neurosci Methods
|
2007
|
0.79
|
|
56
|
Fenofibrate increases the L-arginine:ADMA ratio by increase of L-arginine concentration but has no effect on ADMA concentration.
|
Atherosclerosis
|
2004
|
0.78
|
|
57
|
Effect of chronic elevated asymmetric dimethylarginine (ADMA) levels on granulopoiesis.
|
Ann Hematol
|
2012
|
0.78
|
|
58
|
Effects of stent implementation on plasma levels of asymmetric dimethylarginine in patients with or without ST-segment elevation acute myocardial infarction.
|
Int J Mol Med
|
2010
|
0.78
|
|
59
|
Treatment with niacin lowers ADMA.
|
Atherosclerosis
|
2005
|
0.78
|
|
60
|
Symmetrical dimethylarginine is superior to NT-proBNP for detecting systemic ventricular dysfunction in adults after atrial repair for transposition of the great arteries.
|
Int J Cardiol
|
2013
|
0.78
|
|
61
|
Effects of coronary revascularization with or without cardiopulmonary bypass on plasma levels of asymmetric dimethylarginine.
|
Coron Artery Dis
|
2011
|
0.77
|
|
62
|
Identification and quantification of the atypical metabolite ornithine-lactam in human plasma by liquid chromatography-tandem mass spectrometry (LC-MS/MS).
|
J Chromatogr B Analyt Technol Biomed Life Sci
|
2009
|
0.77
|
|
63
|
Enantioselective quantification of omeprazole and its main metabolites in human serum by chiral HPLC-atmospheric pressure photoionization tandem mass spectrometry.
|
J Chromatogr B Analyt Technol Biomed Life Sci
|
2007
|
0.77
|
|
64
|
Cellular and molecular mechanisms of tissue protection by lipophilic calcium channel blockers.
|
FASEB J
|
2006
|
0.77
|
|
65
|
The effects of G-CSF-induced mobilization of progenitor cells are limited by ADMA.
|
Int J Cardiol
|
2009
|
0.77
|
|
66
|
Concentration of moxifloxacin in serum and human aqueous humor following a single 400 mg oral dose.
|
J Cataract Refract Surg
|
2007
|
0.77
|
|
67
|
Opposite associations of plasma homoarginine and ornithine with arginine in healthy children and adolescents.
|
Int J Mol Sci
|
2013
|
0.76
|
|
68
|
Probing AGXT2 enzyme activity in mouse tissue by applying stable isotope-labeled asymmetric dimethyl arginine as substrate.
|
J Mass Spectrom
|
2012
|
0.76
|
|
69
|
Omeprazole-induced cough in a patient with gastroesophageal reflux disease.
|
Eur J Gastroenterol Hepatol
|
2010
|
0.76
|
|
70
|
Associations between endogenous dimethylarginines and renal function in healthy children and adolescents.
|
Int J Mol Sci
|
2012
|
0.76
|
|
71
|
Improved method for the determination of cyclic guanosine monophosphate (cGMP) in human plasma by LC-MS/MS.
|
J Chromatogr B Analyt Technol Biomed Life Sci
|
2009
|
0.76
|
|
72
|
Functional changes in the ageing kidney: is there a role for asymmetric dimethylarginine?
|
Nephrol Dial Transplant
|
2003
|
0.76
|
|
73
|
Tetraparesis associated with colchicine is probably due to inhibition by verapamil of the P-glycoprotein efflux pump in the blood-brain barrier.
|
BMJ
|
2005
|
0.75
|
|
74
|
Methotrexate treatment and mortality in rheumatoid arthritis.
|
Lancet
|
2002
|
0.75
|
|
75
|
Recurrent seizures in a levetiracetam-treated patient after subarachnoid hemorrhage: a matter of enhanced renal function?
|
Epilepsy Behav
|
2012
|
0.75
|
|
76
|
Pharmacokinetics and dose recommendations of Niaspan® in chronic kidney disease and dialysis patients.
|
Nephrol Dial Transplant
|
2010
|
0.75
|
|
77
|
Elevated plasma asymmetric dimethyl-L-arginine in a patient with Gordon syndrome.
|
Nephrol Dial Transplant
|
2006
|
0.75
|
|
78
|
Procedure-related pulmonary hypertension in patients with hepatocellular carcinoma undergoing percutaneous ethanol injection--role of ethanol, hemolysis, asymmetric dimethylarginine, and the nitric oxide system.
|
Crit Care Med
|
2009
|
0.75
|
|
79
|
Aortic thrombus and pulmonary embolism in a patient with hyperhomocysteinemia.
|
Nat Clin Pract Cardiovasc Med
|
2006
|
0.75
|
|
80
|
Valproic acid-induced myopathy in a patient with schizoaffective disorder.
|
J Clin Psychopharmacol
|
2009
|
0.75
|