Published in Cancer Sci on January 19, 2010
Phase II study of alisertib, a selective Aurora A kinase inhibitor, in relapsed and refractory aggressive B- and T-cell non-Hodgkin lymphomas. J Clin Oncol (2013) 2.46
The investigational Aurora kinase A inhibitor MLN8237 induces defects in cell viability and cell-cycle progression in malignant bladder cancer cells in vitro and in vivo. Clin Cancer Res (2013) 1.62
Efficacy of novel histone deacetylase inhibitor, AR42, in a mouse model of, human T-lymphotropic virus type 1 adult T cell lymphoma. Leuk Res (2011) 1.53
Aurora kinase inhibitors as anticancer molecules. Biochim Biophys Acta (2010) 1.33
Aurora A inhibitor (MLN8237) plus vincristine plus rituximab is synthetic lethal and a potential curative therapy in aggressive B-cell non-Hodgkin lymphoma. Clin Cancer Res (2012) 1.17
Development of o-chlorophenyl substituted pyrimidines as exceptionally potent aurora kinase inhibitors. J Med Chem (2012) 1.09
Inhibition of mitotic Aurora kinase A by alisertib induces apoptosis and autophagy of human gastric cancer AGS and NCI-N78 cells. Drug Des Devel Ther (2015) 0.99
The JAK inhibitor AZD1480 regulates proliferation and immunity in Hodgkin lymphoma. Blood Cancer J (2011) 0.93
A functional cooperativity between Aurora A kinase and LIM kinase1: implication in the mitotic process. Cell Cycle (2012) 0.91
Investigational Aurora A kinase inhibitor alisertib (MLN8237) as an enteric-coated tablet formulation in non-hematologic malignancies: phase 1 dose-escalation study. Invest New Drugs (2014) 0.90
Alisertib, an Aurora kinase A inhibitor, induces apoptosis and autophagy but inhibits epithelial to mesenchymal transition in human epithelial ovarian cancer cells. Drug Des Devel Ther (2015) 0.84
Multimodal effects of small molecule ROCK and LIMK inhibitors on mitosis, and their implication as anti-leukemia agents. PLoS One (2014) 0.83
Aurora A Kinase Inhibition Selectively Synergizes with Histone Deacetylase Inhibitor through Cytokinesis Failure in T-cell Lymphoma. Clin Cancer Res (2015) 0.81
Issues in interpreting the in vivo activity of Aurora-A. Expert Opin Ther Targets (2014) 0.80
Identification of novel compounds that enhance colon cancer cell sensitivity to inflammatory apoptotic ligands. Cancer Biol Ther (2013) 0.78
Phase 1 study of the investigational Aurora A kinase inhibitor alisertib (MLN8237) in East Asian cancer patients: pharmacokinetics and recommended phase 2 dose. Invest New Drugs (2015) 0.78
A SILAC-based proteomics elicits the molecular interactome of alisertib (MLN8237) in human erythroleukemia K562 cells. Am J Transl Res (2015) 0.77
Novel immunotherapy for adult T-cell leukemia/lymphoma: Targeting aurora kinase A. Oncoimmunology (2016) 0.75
Cucurbitacin B exerts anti-cancer activities in human multiple myeloma cells in vitro and in vivo by modulating multiple cellular pathways. Oncotarget (2017) 0.75
Retracted Inhibition of constitutively active Jak-Stat pathway suppresses cell growth of human T-cell leukemia virus type 1-infected T-cell lines and primary adult T-cell leukemia cells. Retrovirology (2006) 1.60
Retracted NF-kappaB activation by Helicobacter pylori requires Akt-mediated phosphorylation of p65. BMC Microbiol (2009) 1.59
Lack of nucleophosmin mutation in patients with myelodysplastic syndrome and acute myeloid leukemia with chromosome 5 abnormalities. Leuk Lymphoma (2007) 1.59
Methylation analysis of the adenomatous polyposis coli (APC) gene in adult T-cell leukemia/lymphoma. Leuk Res (2005) 1.56
Contrast-enhanced harmonic endoscopic ultrasonography in the differential diagnosis of gallbladder wall thickening. Dig Dis Sci (2014) 1.55
Structural dynamics of cereal mitochondrial genomes as revealed by complete nucleotide sequencing of the wheat mitochondrial genome. Nucleic Acids Res (2005) 1.55
Physically discrete beta-lactamase-type thioesterase catalyzes product release in atrochrysone synthesis by iterative type I polyketide synthase. Chem Biol (2009) 1.48
Retracted Molecular characterization of Legionella pneumophila-induced interleukin-8 expression in T cells. BMC Microbiol (2010) 1.46
Transcriptional activation of survivin through the NF-kappaB pathway by human T-cell leukemia virus type I tax. Int J Cancer (2005) 1.46
Scheloribatid mites as the source of pumiliotoxins in dendrobatid frogs. J Chem Ecol (2005) 1.22
Photoreceptor synaptic protein HRG4 (UNC119) interacts with ARL2 via a putative conserved domain. FEBS Lett (2003) 1.18
Rapid tumor formation of human T-cell leukemia virus type 1-infected cell lines in novel NOD-SCID/gammac(null) mice: suppression by an inhibitor against NF-kappaB. J Virol (2003) 1.14
Molecular requirements for T cell recognition of N-myristoylated peptides derived from the simian immunodeficiency virus Nef protein. J Virol (2012) 1.14
Marker-assisted pyramiding of brown planthopper (Nilaparvata lugens Stål) resistance genes Bph1 and Bph2 on rice chromosome 12. Hereditas (2004) 1.12
Phenylpropanoid amides of serotonin accumulate in witches' broom diseased bamboo. Phytochemistry (2003) 1.11
Esophagectomy: is it necessary after chemoradiotherapy for a locally advanced T4 esophageal cancer? Prospective nonrandomized trial comparing chemoradiotherapy with surgery versus without surgery. World J Surg (2005) 1.07
Accumulation of HDMBOA-Glc is induced by biotic stresses prior to the release of MBOA in maize leaves. Phytochemistry (2004) 1.07
Novel quantitative perfusion analysis with contrast-enhanced harmonic EUS for differentiation of autoimmune pancreatitis from pancreatic carcinoma. Scand J Gastroenterol (2012) 1.04
Targeted inactivation of synaptic HRG4 (UNC119) causes dysfunction in the distal photoreceptor and slow retinal degeneration, revealing a new function. Exp Eye Res (2006) 1.02
Retracted Curcumin (diferuloylmethane) inhibits constitutive active NF-kappaB, leading to suppression of cell growth of human T-cell leukemia virus type I-infected T-cell lines and primary adult T-cell leukemia cells. Int J Cancer (2006) 1.02
Possible involvement of aryl hydrocarbon receptor (AhR) in adult T-cell leukemia (ATL) leukemogenesis: constitutive activation of AhR in ATL. Biochem Biophys Res Commun (2003) 1.00
Anti-adult T-cell leukemia effects of brown algae fucoxanthin and its deacetylated product, fucoxanthinol. Int J Cancer (2008) 1.00
Retracted Dengue virus-induced apoptosis in hepatic cells is partly mediated by Apo2 ligand/tumour necrosis factor-related apoptosis-inducing ligand. J Gen Virol (2005) 1.00
Tax-independent constitutive IkappaB kinase activation in adult T-cell leukemia cells. Neoplasia (2004) 0.99
Efficient intervention of growth and infiltration of primary adult T-cell leukemia cells by an HIV protease inhibitor, ritonavir. Blood (2005) 0.99
Microarray CGH analyses of chromosomal 20q deletions in patients with hematopoietic malignancies. Cancer Genet (2012) 0.99
The Kaposi's sarcoma-associated herpesvirus K-bZIP protein represses transforming growth factor beta signaling through interaction with CREB-binding protein. Oncogene (2004) 0.99
Fucoidan extracted from Cladosiphon okamuranus Tokida induces apoptosis of human T-cell leukemia virus type 1-infected T-cell lines and primary adult T-cell leukemia cells. Nutr Cancer (2005) 0.97
Retracted Activation of hypoxia-inducible factor 1 in human T-cell leukaemia virus type 1-infected cell lines and primary adult T-cell leukaemia cells. Biochem J (2007) 0.96
Fatty acid amides, previously identified in caterpillars, found in the cricket Teleogryllus taiwanemma and fruit fly Drosophila melanogaster larvae. J Chem Ecol (2007) 0.96
Human T-cell leukemia virus type I-mediated repression of PDZ-LIM domain-containing protein 2 involves DNA methylation but independent of the viral oncoprotein tax. Neoplasia (2009) 0.96
Recent change of the antigenicity and genotype of Japanese encephalitis viruses distributed on Okinawa Island, Japan. Am J Trop Med Hyg (2007) 0.95
Human T-cell leukemia virus type 1 Tax oncoprotein induces and interacts with a multi-PDZ domain protein, MAGI-3. Virology (2004) 0.95
An HIV protease inhibitor, ritonavir targets the nuclear factor-kappaB and inhibits the tumor growth and infiltration of EBV-positive lymphoblastoid B cells. Int J Cancer (2009) 0.93
An unsaturated aliphatic alcohol as a natural ligand for a mouse odorant receptor. Nat Chem Biol (2013) 0.93
Gene expression profile and pathogenicity of biofilm-forming Prevotella intermedia strain 17. BMC Microbiol (2009) 0.93
Fucoidan therapy decreases the proviral load in patients with human T-lymphotropic virus type-1-associated neurological disease. Antivir Ther (2011) 0.92
Retracted Overexpression of caveolin-1 in adult T-cell leukemia. Blood (2010) 0.92
Fatty acid-amino acid conjugates diversification in lepidopteran caterpillars. J Chem Ecol (2010) 0.92
Fucoxanthin and its deacetylated product, fucoxanthinol, induce apoptosis of primary effusion lymphomas. Cancer Lett (2011) 0.92
Retracted Curcumin suppresses constitutive activation of AP-1 by downregulation of JunD protein in HTLV-1-infected T-cell lines. Leuk Res (2005) 0.90
Phosphorylated c-Jun and Fra-1 induce matrix metalloproteinase-1 and thereby regulate invasion activity of 143B osteosarcoma cells. Biochim Biophys Acta (2011) 0.90
Retracted Helicobacter pylori induces CCL20 expression. Infect Immun (2007) 0.90
Activation of AID by human T-cell leukemia virus Tax oncoprotein and the possible role of its constitutive expression in ATL genesis. Carcinogenesis (2010) 0.90
Long-term outcome following imatinib therapy for chronic myelogenous leukemia, with assessment of dosage and blood levels: the JALSG CML202 study. Cancer Sci (2012) 0.89
MicroRNA miR-146a is induced by HTLV-1 tax and increases the growth of HTLV-1-infected T-cells. Int J Cancer (2009) 0.89
Head and neck infections caused by Streptococcus milleri group: an analysis of 17 cases. Auris Nasus Larynx (2005) 0.89
T1 squamous cell carcinoma of the esophagus: long-term outcomes and prognostic factors after esophagectomy. Ann Surg Oncol (2014) 0.89
Retracted Overexpression of Aurora A by loss of CHFR gene expression increases the growth and survival of HTLV-1-infected T cells through enhanced NF-kappaB activity. Int J Cancer (2009) 0.88
Genome size variation in diploid and tetraploid wild wheats. AoB Plants (2010) 0.88
Antitumor activity and macrophage nitric oxide producing action of medicinal herb, Crassocephalum crepidioides. BMC Complement Altern Med (2012) 0.88
Retracted Curcumin targets Akt cell survival signaling pathway in HTLV-I-infected T-cell lines. Cancer Sci (2006) 0.88
Second-line combination chemotherapy with docetaxel for cisplatin-pretreated refractory metastatic esophageal cancer: a preliminary report of initial experience. Chemotherapy (2007) 0.87
Targeting Bcl-2 family proteins in adult T-cell leukemia/lymphoma: in vitro and in vivo effects of the novel Bcl-2 family inhibitor ABT-737. Cancer Lett (2011) 0.87
Effects of hippuristanol, an inhibitor of eIF4A, on adult T-cell leukemia. Biochem Pharmacol (2011) 0.87
Bisphosphonate incadronate inhibits growth of human T-cell leukaemia virus type I-infected T-cell lines and primary adult T-cell leukaemia cells by interfering with the mevalonate pathway. Br J Haematol (2007) 0.86
Retracted Human T-cell leukemia virus type 1 tax dysregulates beta-catenin signaling. J Virol (2006) 0.86
Larval feeding stimulants for a rutaceae-feeding swallowtail butterfly, Papilio xuthus L. in Citrus unshiu leaves. J Chem Ecol (2011) 0.86
Retracted Resistance to Apo2 ligand (Apo2L)/tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis and constitutive expression of Apo2L/TRAIL in human T-cell leukemia virus type 1-infected T-cell lines. J Virol (2005) 0.86
Cutting edge: T cells monitor N-myristoylation of the Nef protein in simian immunodeficiency virus-infected monkeys. J Immunol (2011) 0.86
Mechanisms of Legionella pneumophila-induced interleukin-8 expression in human lung epithelial cells. BMC Microbiol (2007) 0.85
Retracted Helicobacter pylori-induced interleukin-12 p40 expression. Infect Immun (2009) 0.85
Cytotoxic effects of fucoidan nanoparticles against osteosarcoma. Mar Drugs (2013) 0.84
Heavily melanotic perivascular epithelioid clear cell tumor of the kidney. Pathol Int (2004) 0.84
Identification of astigmatid mites using the second internal transcribed spacer (ITS2) region and its application for phylogenetic study. Exp Appl Acarol (2005) 0.84
Active role of fatty acid amino acid conjugates in nitrogen metabolism in Spodoptera litura larvae. Proc Natl Acad Sci U S A (2008) 0.84
Higher serum uric acid and lipoprotein(a) are correlated with coronary spasm. Heart Vessels (2013) 0.84
Aberrant methylation and decreased expression of the RIZ1 gene are frequent in adult acute lymphoblastic leukemia of T-cell phenotype. Leuk Lymphoma (2012) 0.83
Retracted Transactivation of CCL20 gene by Epstein-Barr virus latent membrane protein 1. Br J Haematol (2006) 0.83
A novel mutation in the OPA1 gene in a Japanese patient with optic atrophy. Am J Ophthalmol (2003) 0.83
Painless acute pancreatitis associated with sorafenib treatment: a case report. Med Oncol (2010) 0.83
Retracted Inhibition of heat shock protein-90 modulates multiple functions required for survival of human T-cell leukemia virus type I-infected T-cell lines and adult T-cell leukemia cells. Int J Cancer (2007) 0.83
Human T-cell leukemia virus type 1 tax transactivates the matrix metalloproteinase 7 gene via JunD/AP-1 signaling. Biochim Biophys Acta (2011) 0.83
Potential role of natural killer cells in controlling growth and infiltration of AIDS-associated primary effusion lymphoma cells. Cancer Sci (2006) 0.83
Relationship among human papillomavirus infection, p16(INK4a), p53 and NF-κB activation in penile cancer from northern Thailand. Oncol Lett (2010) 0.82
Absolute configuration of volicitin from the regurgitant of lepidopteran caterpillars and biological activity of volicitin-related compounds. Biosci Biotechnol Biochem (2006) 0.82
Multiple gammac-receptor expression in adult T-cell leukemia. Eur J Haematol (2002) 0.82
Human T cell leukemia virus type I-infected patients with Hashimoto's thyroiditis and Graves' disease. J Clin Endocrinol Metab (2005) 0.82
[A case of retroperitoneal malignant fibrous histiocytoma with marked response to concurrent cisplatin and radiation therapy: a case report]. Hinyokika Kiyo (2007) 0.82
Changes in retinal synaptic proteins in the transgenic model expressing a mutant HRG4 (UNC119). Invest Ophthalmol Vis Sci (2002) 0.82
Ultraweak photon emission from herbivory-injured maize plants. Naturwissenschaften (2005) 0.82
In vitro biosynthesis of volicitin in Spodoptera litura. Insect Biochem Mol Biol (2005) 0.82
A hemiterpene glucoside as a probing deterrent of the bean aphid, Megoura crassicauda, from a non-host vetch, Vicia hirsuta. Phytochemistry (2006) 0.82
Genealogical use of chloroplast DNA variation for intraspecific studies of Aegilops tauschii Coss. Theor Appl Genet (2005) 0.82
Species-specific glucosylation of DIMBOA in larvae of the rice Armyworm. Biosci Biotechnol Biochem (2009) 0.82
Efficient incorporation of unsaturated fatty acids into volicitin-related compounds in Spodoptera litura (Lepidoptera: Noctuidae). Biosci Biotechnol Biochem (2007) 0.81
Anti-tumor activity of fucoidan is mediated by nitric oxide released from macrophages. Int J Oncol (2011) 0.81
Four cases of advanced renal cell carcinoma with pancreatic metastasis successfully treated with radiation therapy. Int J Clin Oncol (2009) 0.81
Genotyping of the Q locus in wheat by a simple PCR-RFLP method. Genes Genet Syst (2009) 0.81
Anticancer effects of marine carotenoids, fucoxanthin and its deacetylated product, fucoxanthinol, on osteosarcoma. Int J Oncol (2013) 0.81
Pathogenesis of Metastatic Calcification and Acute Pancreatitis in Adult T-Cell Leukemia under Hypercalcemic State. Leuk Res Treatment (2011) 0.81
Induction of allergic contact dermatitis by astigmatid mite-derived monoterpene, alpha-acaridial. Biochem Biophys Res Commun (2008) 0.81
Identification of crinosterol from astigamatid mites. Insect Biochem Mol Biol (2007) 0.81
Retracted A modified version of galectin-9 suppresses cell growth and induces apoptosis of human T-cell leukemia virus type I-infected T-cell lines. Int J Cancer (2007) 0.81
Retracted Transactivation of the ICAM-1 gene by CD30 in Hodgkin's lymphoma. Int J Cancer (2006) 0.81
Matrix metalloproteinase-9 and vascular endothelial growth factor: a possible link in adult T-cell leukaemia cell invasion. Br J Haematol (2002) 0.81
Legionella pneumophila infection induces programmed cell death, caspase activation, and release of high-mobility group box 1 protein in A549 alveolar epithelial cells: inhibition by methyl prednisolone. Respir Res (2008) 0.81
Expression of the c-Met proto-oncogene and its possible involvement in liver invasion in adult T-cell leukemia. Clin Cancer Res (2003) 0.81
Retracted Aurora kinase inhibitor AZD1152 negatively affects the growth and survival of HTLV-1-infected T lymphocytes in vitro. Int J Cancer (2010) 0.81
A novel mutation of the OPA1 gene in a Japanese family with optic atrophy type 1. Jpn J Ophthalmol (2002) 0.80