1
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Network organization of the human autophagy system.
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Nature
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2010
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11.38
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2
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A tissue-specific atlas of mouse protein phosphorylation and expression.
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Cell
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2010
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8.65
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3
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Systematic and quantitative assessment of the ubiquitin-modified proteome.
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Mol Cell
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2011
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7.30
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4
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Cancer proliferation gene discovery through functional genomics.
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Science
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2008
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5.41
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5
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Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair.
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Cell
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2009
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5.41
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6
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Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities.
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Nature
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2007
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4.14
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7
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Structure of a Fbw7-Skp1-cyclin E complex: multisite-phosphorylated substrate recognition by SCF ubiquitin ligases.
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Mol Cell
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2007
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3.97
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8
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Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
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Nature
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2013
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3.57
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9
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A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair.
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Mol Cell
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2010
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3.51
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10
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Evolutionary predictions of binding surfaces and interactions.
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Curr Opin Struct Biol
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2002
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3.43
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11
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The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.
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Mol Cell Biol
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2011
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3.01
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12
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The structure of ClpB: a molecular chaperone that rescues proteins from an aggregated state.
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Cell
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2003
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2.89
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13
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An accurate, sensitive, and scalable method to identify functional sites in protein structures.
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J Mol Biol
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2003
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2.87
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14
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Structural clusters of evolutionary trace residues are statistically significant and common in proteins.
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J Mol Biol
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2002
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2.50
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15
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The SIOD disorder protein SMARCAL1 is an RPA-interacting protein involved in replication fork restart.
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Genes Dev
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2009
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2.44
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16
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Defining human ERAD networks through an integrative mapping strategy.
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Nat Cell Biol
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2011
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2.28
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17
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A functional genomic screen identifies a role for TAO1 kinase in spindle-checkpoint signalling.
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Nat Cell Biol
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2007
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2.00
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18
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A large-scale method to measure absolute protein phosphorylation stoichiometries.
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Nat Methods
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2011
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1.87
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19
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A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling.
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Science
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2011
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1.79
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20
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The tumor suppressor CYLD regulates entry into mitosis.
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Proc Natl Acad Sci U S A
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2007
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1.61
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21
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Genome-wide siRNA screen identifies SMCX, EP400, and Brd4 as E2-dependent regulators of human papillomavirus oncogene expression.
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Proc Natl Acad Sci U S A
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2010
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1.57
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22
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Characterization of retinal guanylate cyclase-activating protein 3 (GCAP3) from zebrafish to man.
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Eur J Neurosci
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2002
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1.52
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23
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DNA unwinding by ASCC3 helicase is coupled to ALKBH3-dependent DNA alkylation repair and cancer cell proliferation.
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Mol Cell
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2011
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1.51
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24
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A genome-wide camptothecin sensitivity screen identifies a mammalian MMS22L-NFKBIL2 complex required for genomic stability.
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Mol Cell
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2010
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1.50
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25
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Correct interpretation of comprehensive phosphorylation dynamics requires normalization by protein expression changes.
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Mol Cell Proteomics
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2011
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1.47
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26
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An OBSL1-Cul7Fbxw8 ubiquitin ligase signaling mechanism regulates Golgi morphology and dendrite patterning.
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PLoS Biol
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2011
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1.40
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27
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Evaluation of HCD- and CID-type fragmentation within their respective detection platforms for murine phosphoproteomics.
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Mol Cell Proteomics
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2011
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1.39
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28
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Systematic identification of interactions between host cell proteins and E7 oncoproteins from diverse human papillomaviruses.
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Proc Natl Acad Sci U S A
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2012
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1.33
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29
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M phase phosphorylation of the epigenetic regulator UHRF1 regulates its physical association with the deubiquitylase USP7 and stability.
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Proc Natl Acad Sci U S A
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2012
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1.32
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30
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An FTS/Hook/p107(FHIP) complex interacts with and promotes endosomal clustering by the homotypic vacuolar protein sorting complex.
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Mol Biol Cell
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2008
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1.14
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31
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Cutaneous β-human papillomavirus E6 proteins bind Mastermind-like coactivators and repress Notch signaling.
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Proc Natl Acad Sci U S A
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2012
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1.09
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32
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Identification and proteomic analysis of distinct UBE3A/E6AP protein complexes.
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Mol Cell Biol
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2012
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1.03
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33
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NCoR1 mediates papillomavirus E8;E2C transcriptional repression.
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J Virol
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2010
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1.02
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34
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Alternative ubiquitin activation/conjugation cascades interact with N-end rule ubiquitin ligases to control degradation of RGS proteins.
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Mol Cell
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2011
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0.98
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35
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The histone demethylase LSD1/KDM1A promotes the DNA damage response.
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J Cell Biol
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2013
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0.96
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36
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The ClpB/Hsp104 molecular chaperone-a protein disaggregating machine.
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J Struct Biol
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2004
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0.93
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37
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Evolutionary traces of functional surfaces along G protein signaling pathway.
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Methods Enzymol
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2002
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0.89
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38
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Acceleration of key reactions as a strategy to elucidate the rate-limiting chemistry underlying phototransduction inactivation.
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Invest Ophthalmol Vis Sci
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2003
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0.81
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39
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Computational and biochemical identification of a nuclear pore complex binding site on the nuclear transport carrier NTF2.
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J Mol Biol
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2004
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0.81
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