PubRank

Edward M Rubin

Author PubWeight™ 433.79‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Initial sequencing and comparative analysis of the mouse genome. Nature 2002 96.15
2 Comparative metagenomics of microbial communities. Science 2005 25.88
3 Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Nature 2004 24.40
4 Community structure and metabolism through reconstruction of microbial genomes from the environment. Nature 2004 20.20
5 ChIP-seq accurately predicts tissue-specific activity of enhancers. Nature 2009 18.38
6 A phylogeny-driven genomic encyclopaedia of Bacteria and Archaea. Nature 2009 15.06
7 VISTA: computational tools for comparative genomics. Nucleic Acids Res 2004 13.52
8 In vivo enhancer analysis of human conserved non-coding sequences. Nature 2006 10.60
9 Phylogenetic shadowing of primate sequences to find functional regions of the human genome. Science 2003 9.93
10 Scanning human gene deserts for long-range enhancers. Science 2003 9.75
11 Insights into the phylogeny and coding potential of microbial dark matter. Nature 2013 8.55
12 Sequencing and analysis of Neanderthal genomic DNA. Science 2006 8.06
13 Metagenomics: DNA sequencing of environmental samples. Nat Rev Genet 2005 7.65
14 Metagenomic and functional analysis of hindgut microbiota of a wood-feeding higher termite. Nature 2007 7.42
15 rVista for comparative sequence-based discovery of functional transcription factor binding sites. Genome Res 2002 7.33
16 Metagenomic discovery of biomass-degrading genes and genomes from cow rumen. Science 2011 6.93
17 Genomic views of distant-acting enhancers. Nature 2009 6.27
18 A distal enhancer and an ultraconserved exon are derived from a novel retroposon. Nature 2006 5.98
19 Genome sequencing and analysis of the biomass-degrading fungus Trichoderma reesei (syn. Hypocrea jecorina). Nat Biotechnol 2008 5.38
20 Symbiosis insights through metagenomic analysis of a microbial consortium. Nature 2006 5.04
21 Deletion of ultraconserved elements yields viable mice. PLoS Biol 2007 4.81
22 Genome-wide experimental determination of barriers to horizontal gene transfer. Science 2007 4.37
23 ChIP-Seq identification of weakly conserved heart enhancers. Nat Genet 2010 4.32
24 Close sequence comparisons are sufficient to identify human cis-regulatory elements. Genome Res 2006 3.92
25 Accelerated evolution of conserved noncoding sequences in humans. Science 2006 3.87
26 Human-specific gain of function in a developmental enhancer. Science 2008 3.84
27 Metagenomic analysis of a permafrost microbial community reveals a rapid response to thaw. Nature 2011 3.80
28 Targeted deletion of the 9p21 non-coding coronary artery disease risk interval in mice. Nature 2010 3.77
29 Ultraconservation identifies a small subset of extremely constrained developmental enhancers. Nat Genet 2008 3.55
30 Comparative genomics at the vertebrate extremes. Nat Rev Genet 2004 3.50
31 Genomic sequencing of Pleistocene cave bears. Science 2005 3.40
32 Improving the coverage of the cyanobacterial phylum using diversity-driven genome sequencing. Proc Natl Acad Sci U S A 2012 3.26
33 Two independent apolipoprotein A5 haplotypes influence human plasma triglyceride levels. Hum Mol Genet 2002 2.71
34 Large-scale discovery of enhancers from human heart tissue. Nat Genet 2011 2.70
35 Megabase deletions of gene deserts result in viable mice. Nature 2004 2.68
36 Automated whole-genome multiple alignment of rat, mouse, and human. Genome Res 2004 2.64
37 Genomic deletion of a long-range bone enhancer misregulates sclerostin in Van Buchem disease. Genome Res 2005 2.61
38 A regulatory SNP causes a human genetic disease by creating a new transcriptional promoter. Science 2006 2.58
39 Metagenome, metatranscriptome and single-cell sequencing reveal microbial response to Deepwater Horizon oil spill. ISME J 2012 2.45
40 A high-resolution enhancer atlas of the developing telencephalon. Cell 2013 2.34
41 The Ter mutation in the dead end gene causes germ cell loss and testicular germ cell tumours. Nature 2005 2.29
42 The DNA sequence and biology of human chromosome 19. Nature 2004 2.29
43 Relative contribution of variation within the APOC3/A4/A5 gene cluster in determining plasma triglycerides. Hum Mol Genet 2002 2.27
44 Fine tuning of craniofacial morphology by distant-acting enhancers. Science 2013 2.16
45 Endothelial lipase is a major determinant of HDL level. J Clin Invest 2003 2.12
46 Apolipoprotein A-V deficiency results in marked hypertriglyceridemia attributable to decreased lipolysis of triglyceride-rich lipoproteins and removal of their remnants. Arterioscler Thromb Vasc Biol 2005 2.06
47 Phylo-VISTA: interactive visualization of multiple DNA sequence alignments. Bioinformatics 2004 1.97
48 Apolipoprotein A5, a newly identified gene that affects plasma triglyceride levels in humans and mice. Arterioscler Thromb Vasc Biol 2002 1.90
49 The airborne metagenome in an indoor urban environment. PLoS One 2008 1.81
50 Identification of ancient remains through genomic sequencing. Genome Res 2008 1.72
51 Metagenomic insights into evolution of a heavy metal-contaminated groundwater microbial community. ISME J 2010 1.71
52 The DNA sequence and comparative analysis of human chromosome 5. Nature 2004 1.62
53 Tenascin-X deficiency mimics Ehlers-Danlos syndrome in mice through alteration of collagen deposition. Nat Genet 2002 1.60
54 In vivo characterization of a vertebrate ultraconserved enhancer. Genomics 2005 1.49
55 Mapping cis-regulatory domains in the human genome using multi-species conservation of synteny. Hum Mol Genet 2005 1.49
56 The sequence and analysis of duplication-rich human chromosome 16. Nature 2004 1.38
57 Apolipoprotein A5, a crucial determinant of plasma triglyceride levels, is highly responsive to peroxisome proliferator-activated receptor alpha activators. J Biol Chem 2003 1.31
58 Characterization of the dog Agouti gene and a nonagoutimutation in German Shepherd Dogs. Mamm Genome 2004 1.28
59 Functional autonomy of distant-acting human enhancers. Genomics 2009 1.25
60 Sequencing of multiple clostridial genomes related to biomass conversion and biofuel production. J Bacteriol 2010 1.25
61 Exploiting human--fish genome comparisons for deciphering gene regulation. Hum Mol Genet 2004 1.25
62 Transgenic mouse in vivo library of human Down syndrome critical region 1: association between DYRK1A overexpression, brain development abnormalities, and cell cycle protein alteration. J Neuropathol Exp Neurol 2004 1.20
63 A vast collection of microbial genes that are toxic to bacteria. Genome Res 2012 1.19
64 Linkage and association between distinct variants of the APOA1/C3/A4/A5 gene cluster and familial combined hyperlipidemia. Arterioscler Thromb Vasc Biol 2003 1.17
65 Haplotype analysis of the apolipoprotein gene cluster on human chromosome 11. Genomics 2004 1.17
66 Intraspecies sequence comparisons for annotating genomes. Genome Res 2004 1.15
67 Genome-wide nucleosome map and cytosine methylation levels of an ancient human genome. Genome Res 2013 1.12
68 Comparative genomic tools and databases: providing insights into the human genome. J Clin Invest 2003 1.10
69 Detection of weakly conserved ancestral mammalian regulatory sequences by primate comparisons. Genome Biol 2007 1.08
70 Basal chromatin modification at the IL-4 gene in helper T cells. J Immunol 2003 1.05
71 Insulin-mediated down-regulation of apolipoprotein A5 gene expression through the phosphatidylinositol 3-kinase pathway: role of upstream stimulatory factor. Mol Cell Biol 2005 1.02
72 Genetic variation responsible for mouse strain differences in integrin alpha 2 expression is associated with altered platelet responses to collagen. Blood 2004 1.01
73 Application of sequence-based methods in human microbial ecology. Genome Res 2006 1.01
74 Mouse strain-specific differences in vascular wall gene expression and their relationship to vascular disease. Arterioscler Thromb Vasc Biol 2004 0.99
75 Paraoxonase 1 overexpression in mice and its effect on high-density lipoproteins. Biochem Biophys Res Commun 2002 0.94
76 Primate-specific evolution of an LDLR enhancer. Genome Biol 2006 0.94
77 Apolipoprotein A-I and the molecular variant apoA-I(Milano): evaluation of the antiatherogenic effects in knock-in mouse model. Atherosclerosis 2005 0.93
78 Paleontology. New tricks with old bones. Science 2008 0.93
79 HDLs in apoA-I transgenic Abca1 knockout mice are remodeled normally in plasma but are hypercatabolized by the kidney. J Lipid Res 2005 0.93
80 Identification of a novel enhancer of brain expression near the apoE gene cluster by comparative genomics. Biochim Biophys Acta 2004 0.93
81 Analysis of apolipoprotein A5, c3, and plasma triglyceride concentrations in genetically engineered mice. Arterioscler Thromb Vasc Biol 2004 0.92
82 Comparative genomic analysis reveals a distant liver enhancer upstream of the COUP-TFII gene. Mamm Genome 2005 0.91
83 Haplotypes in the APOA1-C3-A4-A5 gene cluster affect plasma lipids in both humans and baboons. Hum Mol Genet 2004 0.91
84 Phylogenomically guided identification of industrially relevant GH1 β-glucosidases through DNA synthesis and nanostructure-initiator mass spectrometry. ACS Chem Biol 2014 0.88
85 Comparative genomics reveals functional transcriptional control sequences in the Prop1 gene. Mamm Genome 2007 0.87
86 Functional annotation of mouse mutations in embryonic stem cells by use of expression profiling. Mamm Genome 2004 0.84
87 Genetic determinants of sensitivity to beryllium in mice. J Immunotoxicol 2009 0.83
88 Targeted replacement of mouse apolipoprotein A-I with human ApoA-I or the mutant ApoA-IMilano. Evidence of APOA-IM impaired hepatic secretion. J Biol Chem 2002 0.80
89 Regulation of the expression of the apolipoprotein(a) gene: evidence for a regulatory role of the 5' distal apolipoprotein(a) transcription control region enhancer in yeast artificial chromosome transgenic mice. Arterioscler Thromb Vasc Biol 2003 0.80
90 SNPs in putative regulatory regions identified by human mouse comparative sequencing and transcription factor binding site data. Mamm Genome 2002 0.79
91 High-throughput in vitro glycoside hydrolase (HIGH) screening for enzyme discovery. Angew Chem Int Ed Engl 2011 0.79
92 Human apoB contributes to increased serum total apo(a) level in LPA transgenic mice. Lipids Health Dis 2004 0.78
93 Convergent evolution in primates and an insectivore. Genomics 2004 0.76
94 New cerebellar phenotypes in YAC transgenic mouse in vivo library of human Down syndrome critical region-1. Biochem Biophys Res Commun 2007 0.76
95 Expression profiling and comparative sequence derived insights into lipid metabolism. Curr Opin Lipidol 2002 0.75