| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin.
|
Nat Med
|
2007
|
5.18
|
|
2
|
Sustained dystrophin expression induced by peptide-conjugated morpholino oligomers in the muscles of mdx mice.
|
Mol Ther
|
2008
|
2.69
|
|
3
|
On T2* magnetic resonance and cardiac iron.
|
Circulation
|
2011
|
2.33
|
|
4
|
Hemoglobin H disease: not necessarily a benign disorder.
|
Blood
|
2002
|
1.91
|
|
5
|
A genome-wide association identified the common genetic variants influence disease severity in beta0-thalassemia/hemoglobin E.
|
Hum Genet
|
2010
|
1.75
|
|
6
|
T-type calcium channel blockade improves survival and cardiovascular function in thalassemic mice.
|
Eur J Haematol
|
2012
|
1.61
|
|
7
|
Targeted modification of a human beta-globin locus BAC clone using GET Recombination and an I-Scei counterselection cassette.
|
Genomics
|
2003
|
1.58
|
|
8
|
Platelet inhibition by nitrite is dependent on erythrocytes and deoxygenation.
|
PLoS One
|
2012
|
1.23
|
|
9
|
RNA repair restores hemoglobin expression in IVS2-654 thalassemic mice.
|
Proc Natl Acad Sci U S A
|
2009
|
1.21
|
|
10
|
International reproducibility of single breathhold T2* MR for cardiac and liver iron assessment among five thalassemia centers.
|
J Magn Reson Imaging
|
2010
|
1.14
|
|
11
|
Repair of a splicing defect in erythroid cells from patients with beta-thalassemia/HbE disorder.
|
Mol Ther
|
2002
|
1.11
|
|
12
|
A scoring system for the classification of beta-thalassemia/Hb E disease severity.
|
Am J Hematol
|
2008
|
1.04
|
|
13
|
Flow cytometric quantitation of red blood cell vesicles in thalassemia.
|
Cytometry B Clin Cytom
|
2004
|
1.03
|
|
14
|
Increased circulating activated endothelial cells, vascular endothelial growth factor, and tumor necrosis factor in thalassemia.
|
Am J Hematol
|
2002
|
1.03
|
|
15
|
Restoration of human beta-globin gene expression in murine and human IVS2-654 thalassemic erythroid cells by free uptake of antisense oligonucleotides.
|
Mol Pharmacol
|
2002
|
1.02
|
|
16
|
Parallel assessment of globin lentiviral transfer in induced pluripotent stem cells and adult hematopoietic stem cells derived from the same transplanted β-thalassemia patient.
|
Stem Cells
|
2013
|
1.01
|
|
17
|
T-type calcium channel as a portal of iron uptake into cardiomyocytes of beta-thalassemic mice.
|
Eur J Haematol
|
2010
|
0.98
|
|
18
|
A humanized BAC transgenic/knockout mouse model for HbE/beta-thalassemia.
|
Genomics
|
2006
|
0.97
|
|
19
|
Iron chelation therapy in thalassemia major: a systematic review with meta-analyses of 1520 patients included on randomized clinical trials.
|
Blood Cells Mol Dis
|
2011
|
0.95
|
|
20
|
Activated platelet-derived microparticles in thalassaemia.
|
Br J Haematol
|
2007
|
0.95
|
|
21
|
Fetal globin gene inducers: novel agents and new potential.
|
Ann N Y Acad Sci
|
2010
|
0.95
|
|
22
|
Clinical trial of deferiprone iron chelation therapy in beta-thalassaemia/haemoglobin E patients in Thailand.
|
Br J Haematol
|
2003
|
0.94
|
|
23
|
Prevalence and clinical significance of hepatitis C virus infection in Thai patients with thalassemia.
|
Int J Hematol
|
2003
|
0.93
|
|
24
|
Improvement in oxidative stress and antioxidant parameters in beta-thalassemia/Hb E patients treated with curcuminoids.
|
Clin Biochem
|
2009
|
0.93
|
|
25
|
Iron metabolism in heterozygotes for hemoglobin E (HbE), alpha-thalassemia 1, or beta-thalassemia and in compound heterozygotes for HbE/beta-thalassemia.
|
Am J Clin Nutr
|
2008
|
0.92
|
|
26
|
Antitumor activity and mechanism of action of the iron chelator, Dp44mT, against leukemic cells.
|
Am J Hematol
|
2009
|
0.92
|
|
27
|
UGT1A6 genotype-related pharmacokinetics of deferiprone (L1) in healthy volunteers.
|
Br J Clin Pharmacol
|
2008
|
0.90
|
|
28
|
Molecular analysis of beta-thalassemia in South Vietnam.
|
Am J Hematol
|
2002
|
0.90
|
|
29
|
Hydroxyurea responses and fetal hemoglobin induction in beta-thalassemia/HbE patients' peripheral blood erythroid cell culture.
|
Ann Hematol
|
2006
|
0.90
|
|
30
|
Calibration of myocardial T2 and T1 against iron concentration.
|
J Cardiovasc Magn Reson
|
2014
|
0.88
|
|
31
|
Early detection of cardiac involvement in thalassemia: From bench to bedside perspective.
|
World J Cardiol
|
2013
|
0.88
|
|
32
|
Genetic modifiers in hemoglobinopathies.
|
Curr Mol Med
|
2008
|
0.87
|
|
33
|
Increased erythropoiesis of beta-thalassaemia/Hb E proerythroblasts is mediated by high basal levels of ERK1/2 activation.
|
Br J Haematol
|
2009
|
0.87
|
|
34
|
A humanized mouse model for a common beta0-thalassemia mutation.
|
Genomics
|
2005
|
0.87
|
|
35
|
Accumulation of lipid peroxidation-derived DNA lesions in iron-overloaded thalassemic mouse livers: comparison with levels in the lymphocytes of thalassemia patients.
|
Int J Cancer
|
2009
|
0.87
|
|
36
|
Heart rate variability in beta-thalassemia patients.
|
Eur J Haematol
|
2009
|
0.86
|
|
37
|
Increased oxidative metabolism is associated with erythroid precursor expansion in β0-thalassaemia/Hb E disease.
|
Blood Cells Mol Dis
|
2011
|
0.86
|
|
38
|
BET bromodomain inhibition rescues erythropoietin differentiation of human erythroleukemia cell line UT7.
|
Biochem Biophys Res Commun
|
2012
|
0.84
|
|
39
|
Quantitative determination of ortho- and meta-tyrosine as biomarkers of protein oxidative damage in beta-thalassemia.
|
Redox Rep
|
2007
|
0.84
|
|
40
|
Enhanced activation of autophagy in β-thalassemia/Hb E erythroblasts during erythropoiesis.
|
Ann Hematol
|
2011
|
0.84
|
|
41
|
Effect of Tumor Necrosis Factor-Alpha on Erythropoietin and Erythropoietin Receptor-Induced Erythroid Progenitor Cell Proliferation in β-Thalassemia/Hemoglobin E Patients.
|
Turk J Haematol
|
2015
|
0.84
|
|
42
|
Genetic modifiers of Hb E/beta0 thalassemia identified by a two-stage genome-wide association study.
|
BMC Med Genet
|
2010
|
0.84
|
|
43
|
Multicenter study of the molecular basis of thalassemia intermedia in different ethnic populations.
|
Hemoglobin
|
2007
|
0.84
|
|
44
|
Impaired bone formation and osteopenia in heterozygous β(IVSII-654) knockin thalassemic mice.
|
Histochem Cell Biol
|
2011
|
0.84
|
|
45
|
In vivo and in vitro studies of fetal hemoglobin induction by hydroxyurea in beta-thalassemia/hemoglobin E patients.
|
Exp Hematol
|
2005
|
0.83
|
|
46
|
Association of SNP in exon 1 of HBS1L with hemoglobin F level in beta0-thalassemia/hemoglobin E.
|
Int J Hematol
|
2008
|
0.83
|
|
47
|
Coinheritance of the different copy numbers of alpha-globin gene modifies severity of beta-thalassemia/Hb E disease.
|
Ann Hematol
|
2007
|
0.83
|
|
48
|
Hemin: a possible cause of oxidative stress in blood circulation of beta-thalassemia/hemoglobin E disease.
|
Free Radic Res
|
2003
|
0.83
|
|
49
|
Heart rate variability in beta-thalassemic mice.
|
Int J Cardiol
|
2006
|
0.82
|
|
50
|
Increased urinary 1,N6-ethenodeoxyadenosine and 3,N4-ethenodeoxycytidine excretion in thalassemia patients: markers for lipid peroxidation-induced DNA damage.
|
Free Radic Biol Med
|
2008
|
0.82
|
|
51
|
Insertion of common mutations into the human beta-globin locus using GET Recombination and an EcoRI endonuclease counterselection cassette.
|
J Biotechnol
|
2003
|
0.82
|
|
52
|
Cold exposure down-regulates zebrafish hematopoiesis.
|
Biochem Biophys Res Commun
|
2010
|
0.82
|
|
53
|
A mechanism of ineffective erythropoiesis in β-thalassemia/Hb E disease.
|
Haematologica
|
2009
|
0.82
|
|
54
|
Insight into the peopling of Mainland Southeast Asia from Thai population genetic structure.
|
PLoS One
|
2013
|
0.82
|
|
55
|
Differential plasma proteome profiles of mild versus severe β-thalassemia/Hb E.
|
Ann Hematol
|
2012
|
0.81
|
|
56
|
Characterizations and proteome analysis of platelet-free plasma-derived microparticles in β-thalassemia/hemoglobin E patients.
|
J Proteomics
|
2012
|
0.81
|
|
57
|
Pharmacokinetics of deferiprone in patients with β-thalassaemia: impact of splenectomy and iron status.
|
Clin Pharmacokinet
|
2011
|
0.81
|
|
58
|
Expression of microRNA-451 in normal and thalassemic erythropoiesis.
|
Ann Hematol
|
2010
|
0.81
|
|
59
|
Imbalanced globin chain synthesis determines erythroid cell pathology in thalassemic mice.
|
Haematologica
|
2009
|
0.81
|
|
60
|
Genetic analysis of candidate modifier polymorphisms in Hb E-beta 0-thalassemia patients.
|
Ann N Y Acad Sci
|
2005
|
0.80
|
|
61
|
Mitochondrial calcium uniporter blocker prevents cardiac mitochondrial dysfunction induced by iron overload in thalassemic mice.
|
Biometals
|
2012
|
0.80
|
|
62
|
Iron-chelating and free-radical scavenging activities of microwave-processed green tea in iron overload.
|
Hemoglobin
|
2006
|
0.80
|
|
63
|
Effects of combined UDP-glucuronosyltransferase (UGT) 1A1*28 and 1A6*2 on paracetamol pharmacokinetics in beta-thalassemia/HbE.
|
Pharmacology
|
2006
|
0.80
|
|
64
|
Comparison of pharmacokinetics and urinary iron excretion of two single doses of deferiprone in β-thalassemia/hemoglobin E patients.
|
Pharmacology
|
2012
|
0.80
|
|
65
|
Calcium channels and iron uptake into the heart.
|
World J Cardiol
|
2011
|
0.80
|
|
66
|
Cytokine-induced apoptosis of beta-thalassemia/hemoglobin E erythroid progenitor cells via nitric oxide-mediated process in vitro.
|
Acta Haematol
|
2011
|
0.80
|
|
67
|
Pharmaco/ferrokinetic-related pro-oxidant activity of deferiprone in beta-thalassemia.
|
Free Radic Res
|
2009
|
0.79
|
|
68
|
In vitro antimicrobial activity of volatile organic compounds from Muscodor crispans against the pathogenic oomycete Pythium insidiosum.
|
Southeast Asian J Trop Med Public Health
|
2012
|
0.79
|
|
69
|
Rapid diagnosis of alpha-thalassemia by melting curve analysis.
|
J Mol Diagn
|
2010
|
0.79
|
|
70
|
Enhanced erythroid cell differentiation in hypoxic condition is in part contributed by miR-210.
|
Blood Cells Mol Dis
|
2013
|
0.79
|
|
71
|
Molecular analysis of globin gene expression in different thalassaemia disorders: individual variation of β(E) pre-mRNA splicing determine disease severity.
|
Br J Haematol
|
2011
|
0.79
|
|
72
|
Glutathione redox system in β -thalassemia/Hb E patients.
|
ScientificWorldJournal
|
2013
|
0.79
|
|
73
|
An in vivo model for analysis of developmental erythropoiesis and globin gene regulation.
|
FASEB J
|
2014
|
0.78
|
|
74
|
Molecular screening of the Hbs Constant Spring (codon 142, TAA>CAA, α2) and Paksé (codon 142, TAA>TAT, α2) mutations in Thailand.
|
Hemoglobin
|
2010
|
0.78
|
|
75
|
The effects of vitamin E on platelet activity in beta-thalassaemia patients.
|
Br J Haematol
|
2003
|
0.78
|
|
76
|
Rescued mice with Hb E transgene-developed red cell changes similar to human beta-thalassemia/HbE disease.
|
Ann N Y Acad Sci
|
2005
|
0.78
|
|
77
|
Quantitative analysis of Hb Bart's in cord blood by capillary electrophoresis system.
|
Ann Hematol
|
2010
|
0.78
|
|
78
|
Paraoxonase and platelet-activating factor acetylhydrolase activities in lipoproteins of beta-thalassemia/hemoglobin E patients.
|
Clin Chem Lab Med
|
2007
|
0.77
|
|
79
|
Proteomic analysis of hemoglobin H-constant spring (Hb H-CS) erythroblasts.
|
Blood Cells Mol Dis
|
2011
|
0.77
|
|
80
|
Rapid diagnosis of thalassemias and other hemoglobinopathies by capillary electrophoresis system.
|
Transl Res
|
2008
|
0.77
|
|
81
|
Molecular basis and hematological features of hemoglobin variants in Southern Thailand.
|
Int J Hematol
|
2010
|
0.77
|
|
82
|
The signaling pathways of erythropoietin and interferon-gamma differ in preventing the apoptosis of mature erythroid progenitor cells.
|
Int J Hematol
|
2003
|
0.77
|
|
83
|
Noninvasive prenatal diagnosis for hemoglobin Bart's hydrops fetalis.
|
Int J Hematol
|
2005
|
0.77
|
|
84
|
Two cases of compound heterozygosity for Hb Hekinan [alpha27(B8)Glu-->Asp (alpha1)] and alpha-thalassemia in Thailand.
|
Hemoglobin
|
2004
|
0.77
|
|
85
|
Genotypes and phenotypes of thalassemia: A discussion.
|
Ann N Y Acad Sci
|
2005
|
0.77
|
|
86
|
Elevated F2-isoprostanes in thalassemic patients.
|
Free Radic Biol Med
|
2007
|
0.77
|
|
87
|
Phenotypic characterization of circulating CD4/CD8 T-lymphocytes in β-thalassemia patients.
|
Asian Pac J Allergy Immunol
|
2014
|
0.76
|
|
88
|
Characterisation of a novel oral iron chelator: 1-(N-Acetyl-6-Aminohexyl)-3-Hydroxy-2-Methylpyridin-4-one.
|
J Pharm Pharmacol
|
2015
|
0.76
|
|
89
|
Association between promoter and coding region mutations of UDP-glucuronosyltransferase 1A1 and beta-thalassemia/Hb E with cholelithiasis.
|
Eur J Haematol
|
2007
|
0.76
|
|
90
|
Ferric iron uptake into cardiomyocytes of β-thalassemic mice is not through calcium channels.
|
Drug Chem Toxicol
|
2012
|
0.76
|
|
91
|
Nitric oxide and caspase 3 mediated cytokine induced apoptosis in acute leukemia.
|
Asian Pac J Allergy Immunol
|
2011
|
0.76
|
|
92
|
Hb Siam [alpha15(A13)Gly-->Arg (alpha1) (GGT-->CGT)] is a typical alpha chain hemoglobinopathy without an alpha-thalassemic effect.
|
Hemoglobin
|
2002
|
0.76
|
|
93
|
Effect of coenzyme Q10 as an antioxidant in beta-thalassemia/Hb E patients.
|
Biofactors
|
2005
|
0.76
|
|
94
|
Cardiomyocyte ultrastructural damage in β-thalassaemic mice.
|
Int J Exp Pathol
|
2013
|
0.76
|
|
95
|
Role of interleukin-3 and signaling pathways on beta-thalassemia/HbE erythroid progenitor cell in culture.
|
Southeast Asian J Trop Med Public Health
|
2007
|
0.76
|
|
96
|
Role of curcuminoids in ameliorating oxidative modification in β-thalassemia/Hb E plasma proteome.
|
J Nutr Biochem
|
2012
|
0.76
|
|
97
|
Insertion of modifications in the beta-globin locus using GET recombination with single-stranded oligonucleotides and denatured PCR fragments.
|
Mol Biotechnol
|
2003
|
0.75
|
|
98
|
Inhibition of alpha-globin gene expression by RNAi.
|
Biochem Biophys Res Commun
|
2008
|
0.75
|
|
99
|
Correction: Hemoglobin E Prevalence among Ethnic Groups Residing in Malaria-Endemic Areas of Northern Thailand and Its Lack of Association with Plasmodium falciparum Invasion In Vitro.
|
PLoS One
|
2016
|
0.75
|
|
100
|
A reduced curcuminoid analog as a novel inducer of fetal hemoglobin.
|
Ann Hematol
|
2012
|
0.75
|
|
101
|
Clinical severity of β-thalassaemia/Hb E disease is associated with differential activities of the calpain-calpastatin proteolytic system.
|
PLoS One
|
2012
|
0.75
|
|
102
|
The reduction of cholesteryl linoleate in lipoproteins: an index of clinical severity in beta-thalassemia/Hb E.
|
Clin Chem Lab Med
|
2006
|
0.75
|
|
103
|
Genetic polymorphisms and implications for human diseases.
|
J Med Assoc Thai
|
2007
|
0.75
|
|
104
|
p53 and nitric oxide are involved in cytokine-induced apoptosis in Kasumi-1 and Molt-4 Leukemics cells.
|
Asian Pac J Allergy Immunol
|
2014
|
0.75
|
|
105
|
Chicken egg yolk antibodies specific for the gamma chain of human hemoglobin for diagnosis of thalassemia.
|
Int J Hematol
|
2006
|
0.75
|
|
106
|
Molecular mechanism of beta-thalassaemia caused by 22-bp duplication.
|
Ann Hematol
|
2008
|
0.75
|
|
107
|
Molecular mechanism of high hemoglobin F production in Southeast Asian-type hereditary persistence of fetal hemoglobin.
|
Int J Hematol
|
2006
|
0.75
|
|
108
|
Single nucleotide polymorphisms and haplotypes of protein C and protein S genes in the Thai population.
|
Blood Coagul Fibrinolysis
|
2006
|
0.75
|
|
109
|
Phenotypic comparison of four thalassemia model mice reconstructed from cryo-banked embryos.
|
Acta Biol Hung
|
2013
|
0.75
|
|
110
|
Modification of platelet shape change parameter by oxidized lipoprotein from beta-thalassemia/Hemoglobin E.
|
J Med Assoc Thai
|
2009
|
0.75
|
|
111
|
Labdane diterpenes from the aerial parts of Curcuma comosa enhance fetal hemoglobin production in an erythroid cell line.
|
J Nat Prod
|
2010
|
0.75
|
|
112
|
Report on the proceedings of the 15th International Conference on Oral Chelation (ICOC) in the Treatment of Thalassemia and Other Diseases at Taichung, Taiwan, April 22-26, 2005.
|
Hemoglobin
|
2006
|
0.75
|
|
113
|
A pharmacokinetic study of paracetamol in Thai beta-thalassemia/HbE patients.
|
Eur J Clin Pharmacol
|
2006
|
0.75
|
|
114
|
Double heterozygosity for Hb Pyrgos [beta83(EF7)Gly-->Asp] and Hb E [beta26(B8)Glu-->Lys] found in association with alpha-thalassemia.
|
Hemoglobin
|
2002
|
0.75
|
|
115
|
Effect of human beta-globin bacterial artificial chromosome transgenesis on embryo cryopreservation in mouse models.
|
Reprod Fertil Dev
|
2010
|
0.75
|
|
116
|
Hb Kodaira II [beta146(HC3)His --> Gln] detected in Thailand.
|
Hemoglobin
|
2003
|
0.75
|
|
117
|
Hb Kurosaki [alpha7(A5)Lys -->Glu (AAG --> GAG)]: an alpha2-globin gene mutation found in Thailand.
|
Hemoglobin
|
2005
|
0.75
|
|
118
|
Decreased nitrite levels in erythrocytes of children with β-thalassemia/hemoglobin E.
|
Nitric Oxide
|
2013
|
0.75
|
|
119
|
Effects of Iron Chelators on Pulmonary Iron Overload and Oxidative Stress in β-Thalassemic Mice.
|
Pharmacology
|
2015
|
0.75
|
|
120
|
Expression of betaE and gamma-globin genes in infants heterozygous for hemoglobin E and double heterozygous for hemoglobin E and alpha-thalassemia.
|
Haematologica
|
2007
|
0.75
|
|
121
|
Platelet activation and platelet-leukocyte interaction in β-thalassemia/hemoglobin E patients with marked nucleated erythrocytosis.
|
Ann Hematol
|
2012
|
0.75
|
|
122
|
Lipid fluidity at different regions in LDL and HDL of beta-thalassemia/Hb E patients.
|
Biochem Biophys Res Commun
|
2006
|
0.75
|
|
123
|
Characterization of a novel deletion causing (deltabeta)0-thalassemia in a Thai family.
|
Am J Hematol
|
2007
|
0.75
|
|
124
|
Vitamin E supplement improves erythrocyte membrane fluidity of thalassemia: an ESR spin labeling study.
|
J Med Assoc Thai
|
2012
|
0.75
|
|
125
|
pHCR: a parallel haplotype configuration reduction algorithm for haplotype interaction analysis.
|
J Hum Genet
|
2009
|
0.75
|