PubRank

Quan Chen

Author PubWeight™ 206.11‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The diploid genome sequence of an Asian individual. Nature 2008 46.29
2 Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 2012 20.08
3 A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Science 2002 9.59
4 Comparative isoschizomer profiling of cytosine methylation: the HELP assay. Genome Res 2006 5.99
5 The DNA methylome of human peripheral blood mononuclear cells. PLoS Biol 2010 4.25
6 CD44 is of functional importance for colorectal cancer stem cells. Clin Cancer Res 2008 3.40
7 Low-level expression of microRNAs let-7d and miR-205 are prognostic markers of head and neck squamous cell carcinoma. Am J Pathol 2009 2.57
8 Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells. Nat Cell Biol 2012 2.56
9 Whole genome DNA methylation analysis based on high throughput sequencing technology. Methods 2010 2.17
10 Objective assessment of deformable image registration in radiotherapy: a multi-institution study. Med Phys 2008 2.15
11 Single base-resolution methylome of the silkworm reveals a sparse epigenomic map. Nat Biotechnol 2010 2.03
12 Exome sequencing reveals mutations in TRPV3 as a cause of Olmsted syndrome. Am J Hum Genet 2012 1.91
13 Parkin ubiquitinates Drp1 for proteasome-dependent degradation: implication of dysregulated mitochondrial dynamics in Parkinson disease. J Biol Chem 2011 1.75
14 An analytical pipeline for genomic representations used for cytosine methylation studies. Bioinformatics 2008 1.64
15 Deformable registration of the planning image (kVCT) and the daily images (MVCT) for adaptive radiation therapy. Phys Med Biol 2006 1.58
16 Essential role of the voltage-dependent anion channel (VDAC) in mitochondrial permeability transition pore opening and cytochrome c release induced by arsenic trioxide. Oncogene 2004 1.57
17 The Bcl-2 homology domain 3 mimetic gossypol induces both Beclin 1-dependent and Beclin 1-independent cytoprotective autophagy in cancer cells. J Biol Chem 2010 1.55
18 Whole-genome sequencing of giant pandas provides insights into demographic history and local adaptation. Nat Genet 2012 1.43
19 Gossypol induces Bax/Bak-independent activation of apoptosis and cytochrome c release via a conformational change in Bcl-2. FASEB J 2006 1.40
20 Elastographic measurement of the area and volume of thermal lesions resulting from radiofrequency ablation: pathologic correlation. AJR Am J Roentgenol 2003 1.39
21 Beclin 1 cleavage by caspase-3 inactivates autophagy and promotes apoptosis. Protein Cell 2010 1.32
22 A systems biology understanding of the synergistic effects of arsenic sulfide and Imatinib in BCR/ABL-associated leukemia. Proc Natl Acad Sci U S A 2009 1.32
23 Superoxide flashes: early mitochondrial signals for oxidative stress-induced apoptosis. J Biol Chem 2011 1.31
24 A simple fixed-point approach to invert a deformation field. Med Phys 2008 1.28
25 Cysteine 62 of Bax is critical for its conformational activation and its proapoptotic activity in response to H2O2-induced apoptosis. J Biol Chem 2008 1.25
26 Automatic re-contouring in 4D radiotherapy. Phys Med Biol 2006 1.25
27 Refinement of glucagon-like peptide 1 docking to its intact receptor using mid-region photolabile probes and molecular modeling. J Biol Chem 2011 1.22
28 Fine mapping of a region of chromosome 11q13 reveals multiple independent loci associated with risk of prostate cancer. Hum Mol Genet 2011 1.17
29 Depression and associated factors in internal migrant workers in China. J Affect Disord 2011 1.13
30 Identification of the protein-protein contact site and interaction mode of human VDAC1 with Bcl-2 family proteins. Biochem Biophys Res Commun 2003 1.11
31 Central role of mitofusin 2 in autophagosome-lysosome fusion in cardiomyocytes. J Biol Chem 2012 1.10
32 Selenite induces redox-dependent Bax activation and apoptosis in colorectal cancer cells. Free Radic Biol Med 2009 1.08
33 As4S4 targets RING-type E3 ligase c-CBL to induce degradation of BCR-ABL in chronic myelogenous leukemia. Proc Natl Acad Sci U S A 2010 1.07
34 Interactions between genetic variants in the adiponectin, adiponectin receptor 1 and environmental factors on the risk of colorectal cancer. PLoS One 2011 1.07
35 PGC-1 beta-regulated mitochondrial biogenesis and function in myotubes is mediated by NRF-1 and ERR alpha. Mitochondrion 2010 1.07
36 Initial clinical experience imaging scatterer size and strain in thyroid nodules. J Ultrasound Med 2006 1.06
37 CD44-positive cancer stem cells expressing cellular prion protein contribute to metastatic capacity in colorectal cancer. Cancer Res 2013 1.05
38 Proteolytic cleavage of cyclin E leads to inactivation of associated kinase activity and amplification of apoptosis in hematopoietic cells. Mol Cell Biol 2002 1.05
39 Mice deficient in Epg5 exhibit selective neuronal vulnerability to degeneration. J Cell Biol 2013 1.05
40 Noise reduction using spatial-angular compounding for elastography. IEEE Trans Ultrason Ferroelectr Freq Control 2004 1.03
41 Molecular signaling toward mitophagy and its physiological significance. Exp Cell Res 2013 1.03
42 Recombinant M. smegmatis vaccine targeted delivering IL-12/GLS into macrophages can induce specific cellular immunity against M. tuberculosis in BALB/c mice. Vaccine 2006 1.01
43 Parkin regulates paclitaxel sensitivity in breast cancer via a microtubule-dependent mechanism. J Pathol 2009 1.00
44 Morphine induces Beclin 1- and ATG5-dependent autophagy in human neuroblastoma SH-SY5Y cells and in the rat hippocampus. Autophagy 2010 1.00
45 Arsenic trioxide (As(2)O(3)) induces apoptosis through activation of Bax in hematopoietic cells. Oncogene 2005 0.99
46 A study on permeability transition pore opening and cytochrome c release from mitochondria, induced by caspase-3 in vitro. FEBS Lett 2002 0.99
47 Appoptosin is a novel pro-apoptotic protein and mediates cell death in neurodegeneration. J Neurosci 2012 0.99
48 Identification of genes regulated by Wnt/beta-catenin pathway and involved in apoptosis via microarray analysis. BMC Cancer 2006 0.98
49 RNF185, a novel mitochondrial ubiquitin E3 ligase, regulates autophagy through interaction with BNIP1. PLoS One 2011 0.98
50 Mechanical stretch induces mitochondria-dependent apoptosis in neonatal rat cardiomyocytes and G2/M accumulation in cardiac fibroblasts. Cell Res 2004 0.98
51 Reciprocal interactions between tumor-associated macrophages and CD44-positive cancer cells via osteopontin/CD44 promote tumorigenicity in colorectal cancer. Clin Cancer Res 2012 0.97
52 One-step on-column affinity refolding purification and functional analysis of recombinant human VDAC1. Biochem Biophys Res Commun 2003 0.96
53 The histone deacetylase inhibitor LBH589 inhibits expression of mitotic genes causing G2/M arrest and cell death in head and neck squamous cell carcinoma cell lines. J Pathol 2009 0.96
54 A novel-designed Escherichia coli for the production of various polyhydroxyalkanoates from inexpensive substrate mixture. Appl Microbiol Biotechnol 2007 0.94
55 Loss-of-function mutations in HOXC13 cause pure hair and nail ectodermal dysplasia. Am J Hum Genet 2012 0.94
56 Redox status of thioredoxin-1 (TRX1) determines the sensitivity of human liver carcinoma cells (HepG2) to arsenic trioxide-induced cell death. Cell Res 2008 0.94
57 Attenuation estimations using envelope echo data: analysis and simulations. Ultrasound Med Biol 2006 0.94
58 Elastographic versus x-ray CT imaging of radio frequency ablation coagulations: an in vitro study. Med Phys 2004 0.93
59 Efficient gamma index calculation using fast Euclidean distance transform. Phys Med Biol 2009 0.93
60 Hypoxia activation of mitophagy and its role in disease pathogenesis. Antioxid Redox Signal 2015 0.93
61 Nitric oxide signaling in stretch-induced apoptosis of neonatal rat cardiomyocytes. FASEB J 2006 0.92
62 Spatial-angular compounding for elastography using beam steering on linear array transducers. Med Phys 2006 0.92
63 Parkin deficiency contributes to pancreatic tumorigenesis by inducing spindle multipolarity and misorientation. Cell Cycle 2013 0.91
64 Caveolin-1 negatively regulates TRAIL-induced apoptosis in human hepatocarcinoma cells. Biochem Biophys Res Commun 2008 0.91
65 Targeted expression of uncoupling protein 2 to mouse liver increases the susceptibility to lipopolysaccharide/galactosamine-induced acute liver injury. Hepatology 2009 0.91
66 G-protein β2 subunit interacts with mitofusin 1 to regulate mitochondrial fusion. Nat Commun 2010 0.91
67 Ultrasound attenuation imaging using compound acquisition and processing. Ultrason Imaging 2003 0.90
68 Natural diterpenoid compound elevates expression of Bim protein, which interacts with antiapoptotic protein Bcl-2, converting it to proapoptotic Bax-like molecule. J Biol Chem 2011 0.90
69 Dysregulation of mitochondrial calcium signaling and superoxide flashes cause mitochondrial genomic DNA damage in Huntington disease. J Biol Chem 2012 0.90
70 Establishment of a human colorectal cancer cell line P6C with stem cell properties and resistance to chemotherapeutic drugs. Acta Pharmacol Sin 2013 0.90
71 Finite element analysis of tissue deformation with a radiofrequency ablation electrode for strain imaging. IEEE Trans Ultrason Ferroelectr Freq Control 2007 0.89
72 Drp1 is dispensable for mitochondria biogenesis in induction to pluripotency but required for differentiation of embryonic stem cells. Stem Cells Dev 2014 0.89
73 Solution structure of human SUMO-3 C47S and its binding surface for Ubc9. Biochemistry 2005 0.88
74 Mitochondrial outer-membrane E3 ligase MUL1 ubiquitinates ULK1 and regulates selenite-induced mitophagy. Autophagy 2015 0.88
75 Structure-based design of peptides against G3BP with cytotoxicity on tumor cells. J Chem Inf Model 2010 0.87
76 Caspase cleavage of cytochrome c1 disrupts mitochondrial function and enhances cytochrome c release. Cell Res 2011 0.87
77 Role of Ca2+ signaling in initiation of stretch-induced apoptosis in neonatal heart cells. Biochem Biophys Res Commun 2003 0.87
78 microRNA-34a promotes DNA damage and mitotic catastrophe. Cell Cycle 2013 0.87
79 The Ultrasonix 500RP: a commercial ultrasound research interface. IEEE Trans Ultrason Ferroelectr Freq Control 2006 0.87
80 Correlation of ultrasonic scatterer size estimates for the statistical analysis and optimization of angular compounding. J Acoust Soc Am 2004 0.87
81 Identification of a novel family of BRAF(V600E) inhibitors. J Med Chem 2012 0.85
82 Uncoupling protein 2 protects testicular germ cells from hyperthermia-induced apoptosis. Biochem Biophys Res Commun 2007 0.85
83 The molecular mechanism studies of chirality effect of PHA-739358 on Aurora kinase A by molecular dynamics simulation and free energy calculations. J Comput Aided Mol Des 2011 0.85
84 Site-specific molecular signatures predict aggressive disease in HNSCC. Head Neck Pathol 2008 0.84
85 Effect of various dissolution systems on the molecular weight of regenerated silk fibroin. Biomacromolecules 2012 0.84
86 Involvement of death receptor signaling in mechanical stretch-induced cardiomyocyte apoptosis. Life Sci 2005 0.84
87 Interesting structural and dynamical behaviors exhibited by the AF-6 PDZ domain upon Bcr peptide binding. Biochemistry 2007 0.84
88 Detection of hypermethylated vimentin in urine of patients with colorectal cancer. J Mol Diagn 2012 0.84
89 The role of Akt on arsenic trioxide suppression of 3T3-L1 preadipocyte differentiation. Cell Res 2005 0.84
90 Cobalt-catalyzed chemoselective insertion of alkene into the ortho C-H bond of benzamide. J Am Chem Soc 2011 0.83
91 [Effects of ginseng total saponin on traumatic brain edema of rats]. Zhongguo Zhong Xi Yi Jie He Za Zhi 2012 0.83
92 Dynamic tomotherapy delivery. Med Phys 2011 0.83
93 Real-time motion-adaptive-optimization (MAO) in TomoTherapy. Phys Med Biol 2009 0.82
94 Relationship between telomerase activity and its subunit expression and inhibitory effect of antisense hTR on pancreatic carcinoma. World J Gastroenterol 2003 0.81
95 Repetitive ischemic preconditioning attenuates inflammatory reaction and brain damage after focal cerebral ischemia in rats: involvement of PI3K/Akt and ERK1/2 signaling pathway. J Mol Neurosci 2014 0.81
96 Threonine 32 (Thr32) of FoxO3 is critical for TGF-β-induced apoptosis via Bim in hepatocarcinoma cells. Protein Cell 2014 0.81
97 Therapeutic gene expression in transduced mesenchymal stem cells can be monitored using a reporter gene. Nucl Med Biol 2012 0.80
98 Multi-patterned dynamics of mitochondrial fission and fusion in a living cell. PLoS One 2012 0.80
99 Disruption of Smad5 gene induces mitochondria-dependent apoptosis in cardiomyocytes. Exp Cell Res 2005 0.80
100 Human Bop is a novel BH3-only member of the Bcl-2 protein family. Protein Cell 2012 0.79
101 Treatment planning to improve delivery accuracy and patient throughput in helical tomotherapy. Int J Radiat Oncol Biol Phys 2009 0.78
102 Pathway engineering results the altered polyhydroxyalkanoates composition in recombinant Escherichia coli. N Biotechnol 2010 0.78
103 Optimization of angular and frequency compounding in ultrasonic attenuation estimations. J Acoust Soc Am 2005 0.78
104 Osteopontin, a possible modulator of cancer stem cells and their malignant niche. Oncoimmunology 2013 0.78
105 A diterpenoid derivate compound targets selenocysteine of thioredoxin reductases and induces Bax/Bak-independent apoptosis. Free Radic Biol Med 2013 0.78
106 Remarkably reduced expression of FoxO3a in metaplastic colorectum, primary colorectal cancer and liver metastasis. J Huazhong Univ Sci Technolog Med Sci 2013 0.78
107 6-hydroximino-4-aza-A-homo-cholest-3-one and related analogue as a potent inducer of apoptosis in cancer cells. Steroids 2012 0.78
108 Parallel/Opposed: IMRT QA using treatment log files is superior to conventional measurement-based method. J Appl Clin Med Phys 2015 0.78
109 Effects of MTHFR genetic polymorphisms on toxicity and clinical response of irinotecan-based chemotherapy in patients with colorectal cancer. Genet Test Mol Biomarkers 2014 0.77
110 Arsenic induces caspase- and mitochondria-mediated apoptosis in Saccharomyces cerevisiae. FEMS Yeast Res 2007 0.77
111 A general solution for catheter position effects for strain estimation in intravascular elastography. Ultrasound Med Biol 2005 0.77
112 Theoretical analysis of the thread effect in helical TomoTherapy. Med Phys 2011 0.77
113 Ultrasonic noninvasive temperature estimation using echoshift gradient maps: simulation results. Ultrason Imaging 2005 0.77
114 Adaptive fractionation therapy: I. Basic concept and strategy. Phys Med Biol 2008 0.77
115 Multiple gene dysfunctions lead to high cancer-susceptibility: evidences from a whole-exome sequencing study. Am J Cancer Res 2011 0.77
116 Shear bond strength of two adhesives to bovine dentin contaminated with various astringents. Am J Dent 2015 0.77
117 Cytotoxic activities of new jadomycin derivatives. J Antibiot (Tokyo) 2005 0.77
118 Evaluation of tomotherapy MVCT image enhancement program for tumor volume delineation. J Appl Clin Med Phys 2011 0.77
119 Adaptive fractionation therapy: II. Biological effective dose. Phys Med Biol 2008 0.77
120 [Therapeutic effects of DNA vaccines in a murine model of Mycobacterium tuberculosis infection]. Zhonghua Jie He He Hu Xi Za Zhi 2005 0.76
121 [The estimation of protective efficacy of the fusion gene vaccine encoding tubercle antigen 85B and MPT64 in mice challenged with Mycobacterium tuberculosis]. Zhonghua Yi Xue Za Zhi 2004 0.76
122 Compact molten globule-like state of hUBF HMG Box1 at extremely low pH. Biochim Biophys Acta 2005 0.76
123 [A study of the protective effect of the DNA vaccine encoding tubercle antigen 85B with MPT64 in mice challenged with Mycobacterium tuberculosis]. Zhonghua Jie He He Hu Xi Za Zhi 2004 0.76
124 Phenylarsine oxide induces apoptosis in Bax- and Bak-deficient cells through upregulation of Bim. Clin Cancer Res 2011 0.76
125 ITGB4-associated junctional epidermolysis bullosa without pylori atresia but profound genito-urinary involvement. Acta Derm Venereol 2015 0.76
126 Structural basis of specific binding between Aurora A and TPX2 by molecular dynamics simulations. J Chem Inf Model 2011 0.76
127 Protective effects of combined Mycobacterium bovis BCG and interleukin-12 vaccination on airway inflammation in a murine model of allergic asthma. Clin Invest Med 2010 0.76
128 Investigation into the regulation mechanisms of TRAIL apoptosis pathway by mathematical modeling. Acta Biochim Biophys Sin (Shanghai) 2010 0.75
129 Dosimetric feasibility of stereotactic body radiation therapy as an alternative to brachytherapy for definitive treatment of medically inoperable early stage endometrial cancer. Radiat Oncol 2014 0.75
130 Multiscale quantum mechanics/electromagnetics simulation for electronic devices. Phys Chem Chem Phys 2011 0.75
131 [HPLC fingerprint study on Chaenomelis fructus and comparative study on different processed products]. Zhong Yao Cai 2013 0.75
132 Cochlioquinone derivatives with apoptosis-inducing effects on HCT116 colon cancer cells from the phytopathogenic fungus Bipolaris luttrellii L439. Chem Biodivers 2014 0.75
133 [Mechanism and influence of silencing TGM1 gene by siRNA on cell cycle distribution of keratinocytes]. Zhonghua Yi Xue Za Zhi 2014 0.75
134 [Construction and expression of the eukaryotic coexpression plasmid containing Ag85B gene of Mycobacterium tuberculosis and IL-12 gene]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2004 0.75
135 Autophagy researchers. Autophagy 2013 0.75
136 Harmonic ultrasound fields through layered liquid media. IEEE Trans Ultrason Ferroelectr Freq Control 2004 0.75
137 A virtual source model for Monte Carlo simulation of helical tomotherapy. J Appl Clin Med Phys 2015 0.75
138 3D dose verification using tomotherapy CT detector array. Int J Radiat Oncol Biol Phys 2011 0.75
139 [Immunogenicity of DNA vaccine encoding fusion protein of Mycobacterium tuberculosis Ag85B and MPT64]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2003 0.75
140 Real-time respiration monitoring using the radiotherapy treatment beam and four-dimensional computed tomography (4DCT)--a conceptual study. Phys Med Biol 2006 0.75
141 [Efficient polyhydroxybutyrate production from cheap resources by recombinant Escherichia coli]. Sheng Wu Gong Cheng Xue Bao 2010 0.75
142 Brittle fracture in associative polymers: the case of ionomer melts. Soft Matter 2016 0.75
143 Exome sequencing reveals mutation in GJA1 as a cause of keratoderma-hypotrichosis-leukonychia totalis syndrome. Hum Mol Genet 2015 0.75
144 Identification of myb genes in Euplotes aediculatus may indicate an early evolutionary process. Gene 2013 0.75
145 Flow imaging of fluids in porous media by magnetization prepared centric-scan SPRITE. J Magn Reson 2008 0.75
146 [Analysis of quality variation and genetic diversity of Desmodium styracifolium from different provenances]. Zhongguo Zhong Yao Za Zhi 2013 0.75
147 Incremental truncation of PHA synthases results in altered product specificity. Enzyme Microb Technol 2012 0.75
148 [The apoptosis-inducing activity of human selenoprotein P shorter isoform]. Zhonghua Zhong Liu Za Zhi 2004 0.75
149 Engineered photoactivatable genetic switches based on the bacterium phage T7 RNA polymerase. ACS Synth Biol 2016 0.75
150 Quantitative discrimination of water and hydrocarbons in porous media by magnetization prepared centric-scan SPRITE. J Magn Reson 2007 0.75
151 Preparation of azafullerene derivatives from fullerene-mixed peroxides and single crystal X-ray structures of azafulleroid and azafullerene. J Am Chem Soc 2008 0.75
152 [Establishment of a lung cancer A549 cell line stable over-expressing integrin linked kinase protein and its biological activity]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2012 0.75
153 [Construction of a siRNA plasmid for knockdown of coronin-1]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2010 0.75